Activated macrophages in HIV encephalitis and a macaque model show increased [3H](R)-PK11195 binding in a PI3-kinase-dependent manner

Neuroscience Letters

Volumn 426, Issue 2, 2007, Pages 117-122

  Venneti, Sriram ^a   Wang, Guoji ^a   Wiley, Clayton A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

HIV encephalitis; Macrophages; Peripheral benzodiazepine receptor; PI3 kinase; PK11195; SIV encephalitis

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BENZODIAZEPINE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROTOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRITIUM; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BAY REGION BINDING SITE; BINDING AFFINITY; BRAIN DEGENERATION; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ISOTOPE LABELING; LIGAND BINDING; MACACA; MACROPHAGE ACTIVATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS ENCEPHALITIS; VIRUS INFECTIVITY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANALYSIS OF VARIANCE; ANIMALS; ANTINEOPLASTIC AGENTS; AUTORADIOGRAPHY; BINDING, COMPETITIVE; BUTADIENES; CHROMONES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENCEPHALITIS; ENZYME INHIBITORS; HIV; ISOQUINOLINES; LIPOPOLYSACCHARIDES; MACACA; MACROPHAGE ACTIVATION; MORPHOLINES; NITRILES; POSITRON-EMISSION TOMOGRAPHY; SIMIAN IMMUNODEFICIENCY VIRUS; TRITIUM;

EID: 34648837112     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.08.053     Document Type: Article

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