Partial conversion of Hansenula polymorpha amine oxidase into a "plant" amine oxidase: Implications for copper chemistry and mechanism

Biochemistry

Volumn 46, Issue 38, 2007, Pages 10817-10827

  Welford, Richard W D ^a,b   Lam, Angel ^a   Mirica, Liviu M ^a   Klinman, Judith P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER AMINE OXIDASES (CAO); COPPER CHEMISTRY; ELECTRON TRANSFER; EUKARYOTIC SOURCES;

CHARGE TRANSFER; LIGANDS; PROTEINS; REDUCTION; SUBSTRATES;

ENZYME KINETICS;

AMINE; AMINE OXIDASE (FLAVIN CONTAINING); COPPER; COPPER AMINE OXIDASE; OXYGEN; SEMIQUINONE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ELECTRON TRANSPORT; ENZYME MECHANISM; HANSENULA POLYMORPHA; POINT MUTATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; REDUCTION;

AMINE OXIDASE (COPPER-CONTAINING); AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BENZOQUINONES; BINDING SITES; CATALYSIS; COPPER; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTRON TRANSPORT; KINETICS; METALLOPROTEINS; MODELS, CHEMICAL; MONOAMINE OXIDASE; OXIDATION-REDUCTION; OXYGEN; PICHIA; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EUKARYOTA; PICHIA ANGUSTA;

EID: 34648825035     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700943r     Document Type: Article

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