A permissive function of phosphoinositide 3-kinase in Ras activation mediated by inhibition of GTPase-activating proteins

Current Biology

Volumn 10, Issue 19, 2000, Pages 1225-1228

  Rubio, Ignacio ^a   Wetzker, Reinhard ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034609756     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00731-4     Document Type: Article

References (15)

1. Cell cycle·dependent activation of Ras
2. Stimulation of p21 ras upon T-cell activation
3. Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C
4. Involvement of Ras and Raf in the G(i)-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase
5. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by ras
6. Insulin-induced p21ras activation does not require protein kinase C, but a protein sensitive to phenylarsine oxide
7. Regulation of rasGTP loading and ras-raf association in neonatal rat ventricular myocytes by G protein-coupled receptor agonista and phorbol ester
8. Synthesis of phosphatidylinositol 3,4,5-trisphosphate in permeabilised neutrophils regulated by receptors and G-proteins
9. Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells
10. Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of lys-802, a residue involved in the phosphate transfer reaction
11. Phosphatidylinositol 3kinase mediates epidermal growth factor-induced activation of the c-jun N-terminal kinase signaling pathway
12. Role of phosphoinositide 3-kinase in activation of Ras and mitogen-activated protein kinase by epidermal growth factor
13. Linkage of G protein-coupled receptors to the mapk signaling pathway through PI 3-kinase γ
14. Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase
15. Phosphatidylinositol-3-OH kinase as a direct target of ras