Association between diencephalic thyroliberin and arterial blood pressure in agouti-yellow and ob/ob mice may be mediated by leptin

Metabolism: Clinical and Experimental

Volumn 56, Issue 10, 2007, Pages 1439-1443

  Burgueño, Adriana L ^a   Landa, Maria S ^a   Schuman, Mariano L ^a   Alvarez, Azucena L ^a   Carabelli, Julieta ^a   García, Silvia I ^a   Pirola, Carlos J ^a  

^a INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CATECHOLAMINE; LEPTIN; PROTIRELIN; SMALL INTERFERING RNA; THYROID HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DIENCEPHALON; HYPERLEPTINEMIA; HYPERTENSION; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYMPATHETIC TONE; THYROID HORMONE BLOOD LEVEL;

ANIMALS; BLOOD PRESSURE; BODY WEIGHT; DIENCEPHALON; EATING; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; THYROTROPIN; THYROTROPIN-RELEASING HORMONE; THYROXINE; TRIIODOTHYRONINE;

EID: 34548681008     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2007.06.008     Document Type: Article

References (31)

1. Zhang Y., Proenca R., Maffei M., et al. Positional cloning of the mouse obese gene and its human homologue. Nature 372 (1994) 425-432
2. Considine R.V., Sinha M.K., Heiman M.L., et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334 (1996) 292-295
3. Maffei M., Halaas J., Ravussin E., et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1 (1995) 1155-1161
4. Bouret S.G., Draper S.J., and Simerly R.B. Trophic action of leptin on hypothalamic neurons that regulate feeding. Science 304 (2004) 108-110
5. Bouret S.G., and Simerly R.B. Minireview: leptin and development of hypothalamic feeding circuits. Endocrinology 145 (2004) 2621-2626
6. Zigman J.M., and Elmquist J.K. Minireview: from anorexia to obesity-the yin and yang of body weight control. Endocrinology 144 (2003) 3749-3756
7. Voisey J., and Van D.A. Agouti: from mouse to man, from skin to fat. Pigment Cell Res 15 (2002) 10-18
8. Lechan R.M., and Fekete C. Chapter 12: the TRH neuron: a hypothalamic integrator of energy metabolism. Prog Brain Res 153C (2006) 209-235
9. Chen M., Celik A., Georgeson K.E., et al. Molecular basis of melanocortin-4 receptor for AGRP inverse agonism. Regul Pept 136 (2006) 40-49
10. Ahima R.S., Prabakaran D., Mantzoros C., et al. Role of leptin in the neuroendocrine response to fasting. Nature 382 (1996) 250-252
11. Harris M., Aschkenasi C., Elias C.F., et al. Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling. J Clin Invest 107 (2001) 111-120
12. Nillni E.A., Vaslet C., Harris M., et al. Leptin regulates prothyrotropin-releasing hormone biosynthesis. Evidence for direct and indirect pathways. J Biol Chem 275 (2000) 36124-36133
13. Perello M., Stuart R.C., and Nillni E.A. The role of intracerebroventricular administration of leptin in the stimulation of prothyrotropin releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology 147 (2006) 3296-3306
14. Sarkar S., Legradi G., and Lechan R.M. Intracerebroventricular administration of alpha-melanocyte stimulating hormone increases phosphorylation of CREB in TRH- and CRH-producing neurons of the hypothalamic paraventricular nucleus. Brain Res 945 (2002) 50-59
15. Sanchez V.C., Goldstein J., Stuart R.C., et al. Regulation of hypothalamic prohormone convertases 1 and 2 and effects on processing of prothyrotropin-releasing hormone. J Clin Invest 114 (2004) 357-369
16. Brownstein M.J., Palkovits M., Saavedra J.M., et al. Thyrotropin-releasing hormone in specific nuclei of rat brain. Science 185 (1974) 267-269
17. Garcia S.I., Porto P.I., Alvarez A.L., et al. Central overexpression of the TRH precursor gene induces hypertension in rats: antisense reversal. Hypertension 30 (1997) 759-766
18. Garcia S.I., and Pirola C.J. Thyrotropin-releasing hormone in cardiovascular pathophysiology. Regul Pept 128 (2005) 239-246
19. Mark A.L., Shaffer R.A., Correia M.L., et al. Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice. J Hypertens 17 (1999) 1949-1953
20. Aizawa-Abe M., Ogawa Y., Masuzaki H., et al. Pathophysiological role of leptin in obesity-related hypertension. J Clin Invest 105 (2000) 1243-1252
21. Harris R.B., Zhou J., Redmann Jr. S.M., et al. A leptin dose-response study in obese (ob/ob) and lean (+/?) mice. Endocrinology 139 (1998) 8-19
22. Garcia S.I., Dabsys S.M., Santajuliana D., et al. Interaction between thyrotrophin-releasing hormone and the muscarinic cholinergic system in rat brain. J Endocrinol 134 (1992) 215-219
23. Landa M.S., Schuman M.L., Burgueno A., et al. SiRNA-mediated silencing of the diencephalic thyrotropin-releasing hormone precursor gene decreases the arterial blood pressure in the obese agouti mice. Front Biosci 12 (2007) 3431-3435
24. Knight W.D., Swoap S.J., Parsons A.D., et al. Central thyrotropin-releasing hormone infusion opposes cardiovascular and metabolic suppression during caloric restriction. Neuroendocrinology 83 (2006) 69-76
25. Mattila J., and Bunag R.D. Sympathomimetic pressor responses to thyrotropin-releasing hormone in rats. Am J Physiol 251 (1986) H86-H92
26. Landa M.S., Garcia S.I., Schuman M.L., et al. Knocking down the diencephalic thyrotropin-releasing hormone precursor gene normalizes obesity-induced hypertension in the rat. Am J Physiol Endocrinol Metab 292 (2007) E1388-E1394
27. Alexander K., Nikodemova M., Kucerova J., et al. Colchicine treatment differently affects releasable thyrotropin-releasing hormone (TRH) pools in the hypothalamic paraventricular nucleus (PVN) and the median eminence (ME). Cell Mol Neurobiol 25 (2005) 681-695
28. Garcia S.I., Dabsys S.M., Martinez V.N., et al. Thyrotropin-releasing hormone hyperactivity in the preoptic area of spontaneously hypertensive rats. Hypertension 26 (1995) 1105-1110
29. Garcia S.I., Alvarez A.L., Porto P.I., et al. Antisense inhibition of thyrotropin-releasing hormone reduces arterial blood pressure in spontaneously hypertensive rats. Hypertension 37 (2001) 365-370
30. Garcia S.I., Landa M.S., Porto P.I., et al. Thyrotropin-releasing hormone decreases leptin and mediates the leptin-induced pressor effect. Hypertension 39 (2002) 491-495
31. Overton J.M., and Williams T.D. Behavioral and physiologic responses to caloric restriction in mice. Physiol Behav 81 (2004) 749-754