-
1
-
-
0033832073
-
Guanylyl cyclases and signaling by cyclic GMP
-
Lucas, K.A. et al. Guanylyl cyclases and signaling by cyclic GMP. Pharmacol. Rev. 52, 375-414 (2000).
-
(2000)
Pharmacol. Rev
, vol.52
, pp. 375-414
-
-
Lucas, K.A.1
-
2
-
-
0034665151
-
Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP
-
Shailubhai, K. et al. Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP. Cancer Res. 60, 5151-5157 (2000).
-
(2000)
Cancer Res
, vol.60
, pp. 5151-5157
-
-
Shailubhai, K.1
-
3
-
-
0345701291
-
Bacterial enterotoxins are associated with resistance to colon cancer
-
Pitari, G.M. et al. Bacterial enterotoxins are associated with resistance to colon cancer. Proc. Natl. Acad. Sci. USA 100, 2695-2699 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2695-2699
-
-
Pitari, G.M.1
-
4
-
-
0035300437
-
Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays
-
Notterman, D.A., Alon, U., Sierk, A.J. & Levine, A.J. Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays. Cancer Res. 61, 3124-3130 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 3124-3130
-
-
Notterman, D.A.1
Alon, U.2
Sierk, A.J.3
Levine, A.J.4
-
5
-
-
0034709572
-
Expression of guanylin is downregulated in mouse and human intestinal adenomas
-
Steinbrecher, K.A. et al. Expression of guanylin is downregulated in mouse and human intestinal adenomas. Biochem. Biophys. Res. Commun. 273, 225-230 (2000).
-
(2000)
Biochem. Biophys. Res. Commun
, vol.273
, pp. 225-230
-
-
Steinbrecher, K.A.1
-
6
-
-
0030962307
-
Gene expression profiles in normal and cancer cells
-
Zhang, L. et al. Gene expression profiles in normal and cancer cells. Science 276, 1268-1272 (1997).
-
(1997)
Science
, vol.276
, pp. 1268-1272
-
-
Zhang, L.1
-
7
-
-
85050704900
-
Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity
-
in press
-
Li, P. et al. Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity. Gastroenterology (in press).
-
Gastroenterology
-
-
Li, P.1
-
8
-
-
33748070507
-
A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer
-
Schulz, S. et al. A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer. Clin. Cancer Res. 12, 4545-4552 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 4545-4552
-
-
Schulz, S.1
-
9
-
-
0025641727
-
Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt
-
Potten, C.S. & Loeffler, M. Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development 110, 1001-1020 (1990).
-
(1990)
Development
, vol.110
, pp. 1001-1020
-
-
Potten, C.S.1
Loeffler, M.2
-
10
-
-
0034096436
-
Stem cells: The intestinal stem cell as a paradigm
-
Bach, S.P., Renehan, A.G. & Potten, C.S. Stem cells: the intestinal stem cell as a paradigm. Carcinogenesis 21, 469-476 (2000).
-
(2000)
Carcinogenesis
, vol.21
, pp. 469-476
-
-
Bach, S.P.1
Renehan, A.G.2
Potten, C.S.3
-
11
-
-
0036898023
-
Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation
-
Steinbrecher, K.A., Wowk, S.A., Rudolph, J.A., Witte, D.P. & Cohen, M.B. Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation. Am. J. Pathol. 161, 2169-2178 (2002).
-
(2002)
Am. J. Pathol
, vol.161
, pp. 2169-2178
-
-
Steinbrecher, K.A.1
Wowk, S.A.2
Rudolph, J.A.3
Witte, D.P.4
Cohen, M.B.5
-
12
-
-
0035824487
-
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
-
Yang, Q., Bermingham, N.A., Finegold, M.J. & Zoghbi, H.Y. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294, 2155-2158 (2001).
-
(2001)
Science
, vol.294
, pp. 2155-2158
-
-
Yang, Q.1
Bermingham, N.A.2
Finegold, M.J.3
Zoghbi, H.Y.4
-
13
-
-
0031906877
-
Guanylin mRNA expression in human intestine and colorectal adenocarcinoma
-
Cohen, M.B., Hawkins, J.A. & Witte, D.P. Guanylin mRNA expression in human intestine and colorectal adenocarcinoma. Lab. Invest. 78, 101-108 (1998).
-
(1998)
Lab. Invest
, vol.78
, pp. 101-108
-
-
Cohen, M.B.1
Hawkins, J.A.2
Witte, D.P.3
-
14
-
-
33846501510
-
Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells
-
Chung, S., Dzeja, P.P., Faustino, R.S., Perez-Terzic, C., Behfar, A. & Terzic, A. Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells. Nat. Clin. Pract. Cardiovasc. Med. 4(suppl. 1): S60-S67 (2007).
-
(2007)
Nat. Clin. Pract. Cardiovasc. Med
, vol.4
, Issue.SUPPL. 1
-
-
Chung, S.1
Dzeja, P.P.2
Faustino, R.S.3
Perez-Terzic, C.4
Behfar, A.5
Terzic, A.6
-
15
-
-
33746141018
-
Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine
-
Gassler, N. et al. Molecular characterisation of non-absorptive and absorptive enterocytes in human small intestine. Gut 55, 1084-1089 (2006).
-
(2006)
Gut
, vol.55
, pp. 1084-1089
-
-
Gassler, N.1
-
16
-
-
0016793387
-
A region of mitochondrial division in the epithelium of the small intestine of the rat
-
Jeynes, B.J. & Altmann, G.G. A region of mitochondrial division in the epithelium of the small intestine of the rat. Anat. Rec. 182, 289-296 (1975).
-
(1975)
Anat. Rec
, vol.182
, pp. 289-296
-
-
Jeynes, B.J.1
Altmann, G.G.2
-
17
-
-
33746906633
-
Mitochondria in cancer
-
Kroemer, G. Mitochondria in cancer. Oncogene 25, 4630-4632 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 4630-4632
-
-
Kroemer, G.1
-
18
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. On the origin of cancer cells. Science 123, 309-314 (1956).
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
19
-
-
0346880067
-
Nitric oxide signaling: Systems integration of oxygen balance in defense of cell integrity
-
Gong, L., Pitari, G.M., Schulz, S. & Waldman, S.A. Nitric oxide signaling: systems integration of oxygen balance in defense of cell integrity. Curr. Opin. Hematol. 11, 7-14 (2004).
-
(2004)
Curr. Opin. Hematol
, vol.11
, pp. 7-14
-
-
Gong, L.1
Pitari, G.M.2
Schulz, S.3
Waldman, S.A.4
-
20
-
-
0347579845
-
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
-
Nisoli, E. et al. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 299, 896-899 (2003).
-
(2003)
Science
, vol.299
, pp. 896-899
-
-
Nisoli, E.1
-
21
-
-
0345827613
-
Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism
-
Ruiz-Stewart, I. et al. Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism. Proc. Natl. Acad. Sci. USA 101, 37-42 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 37-42
-
-
Ruiz-Stewart, I.1
-
23
-
-
33846129453
-
ANP signaling inhibits TGF-beta-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells
-
Li, P. et al. ANP signaling inhibits TGF-beta-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells. J. Appl. Physiol. 102, 390-398 (2007).
-
(2007)
J. Appl. Physiol
, vol.102
, pp. 390-398
-
-
Li, P.1
-
24
-
-
18344372831
-
Cyclins and cdks in development and cancer: A perspective
-
Deshpande, A., Sicinski, P. & Hinds, P.W. Cyclins and cdks in development and cancer: a perspective. Oncogene 24, 2909-2915 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 2909-2915
-
-
Deshpande, A.1
Sicinski, P.2
Hinds, P.W.3
-
25
-
-
9244239811
-
G1 cell-cycle control and cancer
-
Massague, J. G1 cell-cycle control and cancer. Nature 432, 298-306 (2004).
-
(2004)
Nature
, vol.432
, pp. 298-306
-
-
Massague, J.1
-
26
-
-
20144374299
-
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice
-
Sakatani, T. et al. Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science 307, 1976-1978 (2005).
-
(2005)
Science
, vol.307
, pp. 1976-1978
-
-
Sakatani, T.1
-
27
-
-
0035863515
-
Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal
-
Yang, W.C. et al. Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal. Cancer Res. 61, 565-569 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 565-569
-
-
Yang, W.C.1
-
28
-
-
0034933794
-
Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells
-
Pitari, G.M., Di Guglielmo, M.D., Park, J., Schulz, S. & Waldman, S.A. Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells. Proc. Natl. Acad. Sci. USA 98, 7846-7851 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7846-7851
-
-
Pitari, G.M.1
Di Guglielmo, M.D.2
Park, J.3
Schulz, S.4
Waldman, S.A.5
-
29
-
-
0344826531
-
Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice
-
Aoki, K., Tamai, Y., Horiike, S., Oshima, M. & Taketo, M.M. Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice. Nat. Genet. 35, 323-330 (2003).
-
(2003)
Nat. Genet
, vol.35
, pp. 323-330
-
-
Aoki, K.1
Tamai, Y.2
Horiike, S.3
Oshima, M.4
Taketo, M.M.5
-
30
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan, M.B. & Bartek, J. Cell-cycle checkpoints and cancer. Nature 432, 316-323 (2004).
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
31
-
-
0033575920
-
Deregulated cyclin E induces chromosome instability
-
Spruck, C.H., Won, K.A. & Reed, S.I. Deregulated cyclin E induces chromosome instability. Nature 401, 297-300 (1999).
-
(1999)
Nature
, vol.401
, pp. 297-300
-
-
Spruck, C.H.1
Won, K.A.2
Reed, S.I.3
-
32
-
-
33746879141
-
Glycolysis inhibition for anticancer treatment
-
Pelicano, H., Martin, D.S., Xu, R.H. & Huang, P. Glycolysis inhibition for anticancer treatment. Oncogene 25, 4633-4646 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 4633-4646
-
-
Pelicano, H.1
Martin, D.S.2
Xu, R.H.3
Huang, P.4
-
33
-
-
0034682801
-
Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I
-
Smolenski, A., Poller, W., Walter, U. & Lohmann, S.M. Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I. J. Biol. Chem. 275, 25723-25732 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 25723-25732
-
-
Smolenski, A.1
Poller, W.2
Walter, U.3
Lohmann, S.M.4
-
34
-
-
0036690669
-
Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G
-
Deguchi, A., Soh, J.W., Li, H., Pamukcu, R., Thompson, W.J. & Weinstein, I.B. Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G. Mol. Cancer Ther. 1, 803-809 (2002).
-
(2002)
Mol. Cancer Ther
, vol.1
, pp. 803-809
-
-
Deguchi, A.1
Soh, J.W.2
Li, H.3
Pamukcu, R.4
Thompson, W.J.5
Weinstein, I.B.6
-
35
-
-
4043115604
-
Lamellipodial versus filopodial mode of the actin nanomachinery: Pivotal role of the filament barbed end
-
Mejillano, M.R., Kojima, S., Applewhite, D.A., Gertler, F.B., Svitkina, T.M. & Borisy, G.G. Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end. Cell 118, 363-373 (2004).
-
(2004)
Cell
, vol.118
, pp. 363-373
-
-
Mejillano, M.R.1
Kojima, S.2
Applewhite, D.A.3
Gertler, F.B.4
Svitkina, T.M.5
Borisy, G.G.6
-
36
-
-
0034613254
-
Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin
-
Harbeck, B., Huttelmaier, S., Schluter, K., Jockusch, B.M. & Illenberger, S. Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin. J. Biol. Chem. 275, 30817-30825 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 30817-30825
-
-
Harbeck, B.1
Huttelmaier, S.2
Schluter, K.3
Jockusch, B.M.4
Illenberger, S.5
-
37
-
-
33645669923
-
Tumor epithelial cell matrix metalloproteinase-9 is a target for antimetastatic therapy in colorectal cancer
-
Lubbe, W.J. et al. Tumor epithelial cell matrix metalloproteinase-9 is a target for antimetastatic therapy in colorectal cancer. Clin. Cancer Res. 12, 1876-1882 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 1876-1882
-
-
Lubbe, W.J.1
-
38
-
-
0029856172
-
Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues
-
Carrithers, S.L. et al. Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues. Proc. Natl. Acad. Sci. USA 93, 14827-14832 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14827-14832
-
-
Carrithers, S.L.1
-
39
-
-
0036188562
-
In vivo imaging of human colon cancer xenografts in immunodeficient mice using a guanylyl cyclase C - specific ligand
-
Wolfe, H.R. et al. In vivo imaging of human colon cancer xenografts in immunodeficient mice using a guanylyl cyclase C - specific ligand. J. Nucl. Med. 43, 392-399 (2002).
-
(2002)
J. Nucl. Med
, vol.43
, pp. 392-399
-
-
Wolfe, H.R.1
-
40
-
-
28244432560
-
Interruption of homologous desensitization in cyclic guanosine 3′,5′-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins
-
Pitari, G.M., Baksh, R.I., Harris, D.M., Li, P., Kazerounian, S. & Waldman, S.A. Interruption of homologous desensitization in cyclic guanosine 3′,5′-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins. Cancer Res. 65, 11129-11135 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 11129-11135
-
-
Pitari, G.M.1
Baksh, R.I.2
Harris, D.M.3
Li, P.4
Kazerounian, S.5
Waldman, S.A.6
-
41
-
-
34548677817
-
Mucosally-restricted antigens as novel immunological targets for anti-tumor therapy
-
Snook, A., Stafford, B., Eisenlohr, L., Rothstein, J. & Waldman, S. Mucosally-restricted antigens as novel immunological targets for anti-tumor therapy. Biomarkers Med. 1, 187-202 (2007).
-
(2007)
Biomarkers Med
, vol.1
, pp. 187-202
-
-
Snook, A.1
Stafford, B.2
Eisenlohr, L.3
Rothstein, J.4
Waldman, S.5
-
42
-
-
33645969296
-
Bile acids induce ectopic expression of intestinal guanylyl cyclase C through nuclear factor-kappaB and Cdx2 in human esophageal cells
-
Debruyne, P.R. et al. Bile acids induce ectopic expression of intestinal guanylyl cyclase C through nuclear factor-kappaB and Cdx2 in human esophageal cells. Gastroenterology 130, 1191-1206 (2006).
-
(2006)
Gastroenterology
, vol.130
, pp. 1191-1206
-
-
Debruyne, P.R.1
|