Up- and down-regulation of the mechano-gated K2P channel TREK-1 by PIP2 and other membrane phospholipids

Pflugers Archiv European Journal of Physiology

Volumn 455, Issue 1, 2007, Pages 97-103

  Chemin, Jean ^a   Patel, Amanda Jane ^b   Duprat, Fabrice ^b   Sachs, Frederick ^c   Lazdunski, Michel ^b   Honore, Eric ^b  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c UNIVERSITY AT BUFFALO   (United States)

Author keywords

Acidosis; Arachidonic acid; KCNK; PIP2; Poly lysine; Stretch

Indexed keywords

ARACHIDONIC ACID; DIACYLGLYCEROL; ION CHANNEL; MEMBRANE PHOSPHOLIPID; PHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POLYLYSINE; POTASSIUM CHANNEL;

ACIDOSIS; ANIMAL TISSUE; CELL COMPARTMENTALIZATION; CELLULAR DISTRIBUTION; CHANNEL GATING; CONTROLLED STUDY; DOWN REGULATION; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; REVIEW; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DOWN-REGULATION; ELECTROPHYSIOLOGY; FEMALE; GENETIC VECTORS; HIPPOCAMPUS; ION CHANNEL GATING; NEURONS; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOLIPIDS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PREGNANCY; RATS; SEMLIKI FOREST VIRUS; UP-REGULATION;

EID: 34548660057     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0250-2     Document Type: Review

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