A three-dimensional model of mammalian tyrosinase active site accounting for loss of function mutations

Pigment Cell Research

Volumn 20, Issue 5, 2007, Pages 394-401

  Schweikardt, Thorsten ^a   Olivares, Concepción ^b   Solano, Francisco ^b   Jaenicke, Elmar ^a   García Borrón, José Carlos ^b   Decker, Heinz ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF MURCIA   (Spain)

Author keywords

Albinism; Mammalian; Melanogenesis; Mutation; Structure; Tyrosinase

Indexed keywords

COPPER; HISTIDINE; HYDROXYL GROUP; IMIDAZOLE; MONOPHENOL MONOOXYGENASE; OXYGEN; PEPTIDE; PHENYLALANINE; SULFIDE;

ALBINISM; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA HELIX; ELECTROPHORESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME MECHANISM; ENZYME STRUCTURE; HUMAN; HUMAN CELL; MAMMAL; METAL BINDING; MUTATIONAL ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOCHEMISTRY; HISTIDINE; HUMANS; MELANINS; MICE; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MONOPHENOL MONOOXYGENASE; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENYLALANINE; STREPTOMYCES;

MAMMALIA;

EID: 34548558789     PISSN: 08935785     EISSN: 16000749     Source Type: Journal    
DOI: 10.1111/j.1600-0749.2007.00405.x     Document Type: Article

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