Mutations at critical N-glycosylation sites reduce tyrosinase activity by altering folding and quality control

Journal of Biological Chemistry

Volumn 275, Issue 11, 2000, Pages 8169-8175

  Branza Nichita, Norica ^a,b   Negroiu, Gabriela ^a   Petrescu, Andrei J ^a,b   Garman, Elspeth F ^b   Platt, Fran M ^b   Wormald, Mark R ^b   Dwek, Raymond A ^b   Petrescu, Stefana M ^a,b  

^a INSTITUTE OF BIOCHEMISTRY OF THE ROMANIAN ACADEMY   (Romania)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MONOPHENOL MONOOXYGENASE;

ANIMAL CELL; ARTICLE; BINDING SITE; ENZYME ACTIVITY; ENZYME SYNTHESIS; GENE MUTATION; GLYCOSYLATION; NONHUMAN; PIGMENT DISORDER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING;

ANIMALIA; MAMMALIA;

ANIMALS; CALCIUM-BINDING PROTEINS; CALNEXIN; CHO CELLS; COPPER; CRICETINAE; GLYCOPROTEINS; GLYCOSYLATION; METALLOPROTEINS; MICE; MOLECULAR CHAPERONES; MONOPHENOL MONOOXYGENASE; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 0034677754     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.11.8169     Document Type: Article

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