-
1
-
-
0036262319
-
International Union of Pharmacology. XXVIII. Proteinase-activated receptors
-
Hollenberg M D, Compton S J. International Union of Pharmacology. XXVIII. Proteinase-activated receptors. Pharmacol Rev 2002: 54: 203-217.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 203-217
-
-
Hollenberg, M.D.1
Compton, S.J.2
-
2
-
-
13444249470
-
Proteinase-activated receptors: Transducers of proteinase-mediated signaling in inflammation and immune response
-
Steinhoff M, Buddenkotte J, Shpacovitch V et al. Proteinase-activated receptors: Transducers of proteinase-mediated signaling in inflammation and immune response. Endocr Rev 2005: 26: 1-43.
-
(2005)
Endocr Rev
, vol.26
, pp. 1-43
-
-
Steinhoff, M.1
Buddenkotte, J.2
Shpacovitch, V.3
-
3
-
-
15444346942
-
Interactions of mast cell tryptase with thrombin receptors and PAR-2
-
Molino M, Barnathan E S, Numerof R et al. Interactions of mast cell tryptase with thrombin receptors and PAR-2. J Biol Chem 1997: 272: 4043-4049.
-
(1997)
J Biol Chem
, vol.272
, pp. 4043-4049
-
-
Molino, M.1
Barnathan, E.S.2
Numerof, R.3
-
4
-
-
0029113121
-
Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2
-
Nystedt S, Emilsson K, Larsson A K, Strombeck B, Sundelin J. Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. Eur J Biochem 1995: 232: 84-89.
-
(1995)
Eur J Biochem
, vol.232
, pp. 84-89
-
-
Nystedt, S.1
Emilsson, K.2
Larsson, A.K.3
Strombeck, B.4
Sundelin, J.5
-
5
-
-
0032508557
-
Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis
-
Lourbakos A, Chinni C, Thompson P et al. Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis. FEBS Lett 1998: 435: 45-48.
-
(1998)
FEBS Lett
, vol.435
, pp. 45-48
-
-
Lourbakos, A.1
Chinni, C.2
Thompson, P.3
-
6
-
-
0035879347
-
Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells
-
Sun G, Stacey M A, Schmidt M, Mori L, Mattoli S. Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells. J Immunol 2001: 167: 1014-1021.
-
(2001)
J Immunol
, vol.167
, pp. 1014-1021
-
-
Sun, G.1
Stacey, M.A.2
Schmidt, M.3
Mori, L.4
Mattoli, S.5
-
7
-
-
0037797300
-
Neutrophil serine proteinases activate human nonepithelial cells to produce inflammatory cytokines through protease-activated receptor 2
-
Uehara A, Muramoto K, Takada H, Sugawara S. Neutrophil serine proteinases activate human nonepithelial cells to produce inflammatory cytokines through protease-activated receptor 2. J Immunol 2003: 170: 5690-5696.
-
(2003)
J Immunol
, vol.170
, pp. 5690-5696
-
-
Uehara, A.1
Muramoto, K.2
Takada, H.3
Sugawara, S.4
-
8
-
-
0032814121
-
Proteinase-activated receptor-2 in human skin: Tissue distribution and activation of keratinocytes by mast cell tryptase
-
Steinhoff M, Corvera C U, Thoma M S et al. Proteinase-activated receptor-2 in human skin: Tissue distribution and activation of keratinocytes by mast cell tryptase. Exp Dermatol 1999: 8: 282-294.
-
(1999)
Exp Dermatol
, vol.8
, pp. 282-294
-
-
Steinhoff, M.1
Corvera, C.U.2
Thoma, M.S.3
-
9
-
-
0035575784
-
Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2
-
Miike S, McWilliam A S, Kita H. Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2. J Immunol 2001: 167: 6615-6622.
-
(2001)
J Immunol
, vol.167
, pp. 6615-6622
-
-
Miike, S.1
McWilliam, A.S.2
Kita, H.3
-
10
-
-
0141816690
-
Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells
-
Colognato R, Slupsky J R, Jendrach M, Burysek L, Syrovets T, Simmet T. Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells. Blood 2003: 102: 2645-2652.
-
(2003)
Blood
, vol.102
, pp. 2645-2652
-
-
Colognato, R.1
Slupsky, J.R.2
Jendrach, M.3
Burysek, L.4
Syrovets, T.5
Simmet, T.6
-
11
-
-
0030987215
-
Proteinase-activated receptor-2: Expression by human neutrophils
-
Howells G L, Macey M G, Chinni C et al. Proteinase-activated receptor-2: expression by human neutrophils. J Cell Sci 1997: 110: 881-887.
-
(1997)
J Cell Sci
, vol.110
, pp. 881-887
-
-
Howells, G.L.1
Macey, M.G.2
Chinni, C.3
-
12
-
-
33645019672
-
Functional characterization and expression analysis of the proteinase-activated receptor-2 in human cutaneous mast cells
-
Moormann C, Artuc M, Pohl E et al. Functional characterization and expression analysis of the proteinase-activated receptor-2 in human cutaneous mast cells. J Invest Dermatol 2006: 126: 746-755.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 746-755
-
-
Moormann, C.1
Artuc, M.2
Pohl, E.3
-
13
-
-
28444491902
-
The status quo and quo vadis of mast cells
-
Maurer M, Metz M. The status quo and quo vadis of mast cells. Exp Dermatol 2005: 14: 923-929.
-
(2005)
Exp Dermatol
, vol.14
, pp. 923-929
-
-
Maurer, M.1
Metz, M.2
-
14
-
-
0036485026
-
Pathophysiology of pruritus in atopic dermatitis: An overview
-
Stander S, Steinhoff M. Pathophysiology of pruritus in atopic dermatitis: An overview. Exp Dermatol 2002: 11: 12-24.
-
(2002)
Exp Dermatol
, vol.11
, pp. 12-24
-
-
Stander, S.1
Steinhoff, M.2
-
15
-
-
1642279517
-
Protease-activated receptors: Contribution to physiology and disease
-
Ossovskaya V S, Bunnett N W. Protease-activated receptors: Contribution to physiology and disease. Physiol Rev 2004: 84: 579-621.
-
(2004)
Physiol Rev
, vol.84
, pp. 579-621
-
-
Ossovskaya, V.S.1
Bunnett, N.W.2
-
16
-
-
33344473933
-
Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis
-
Noorbakhsh F, Tsutsui S, Vergnolle N et al. Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis. J Exp Med 2006: 203: 425-435.
-
(2006)
J Exp Med
, vol.203
, pp. 425-435
-
-
Noorbakhsh, F.1
Tsutsui, S.2
Vergnolle, N.3
-
17
-
-
0141817942
-
Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo
-
Seeliger S, Derian C K, Vergnolle N et al. Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo. FASEB J 2003: 17: 1871-1885.
-
(2003)
FASEB J
, vol.17
, pp. 1871-1885
-
-
Seeliger, S.1
Derian, C.K.2
Vergnolle, N.3
-
18
-
-
0036840959
-
Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway
-
Schmidlin F, Amadesi S, Dabbagh K et al. Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway. J Immunol 2002: 169: 5315-5321.
-
(2002)
J Immunol
, vol.169
, pp. 5315-5321
-
-
Schmidlin, F.1
Amadesi, S.2
Dabbagh, K.3
-
19
-
-
0037247658
-
Essential role for proteinase-activated receptor-2 in arthritis
-
Ferrell W R, Lockhart J C, Kelso E B et al. Essential role for proteinase-activated receptor-2 in arthritis. J Clin Invest 2003: 111: 35-41.
-
(2003)
J Clin Invest
, vol.111
, pp. 35-41
-
-
Ferrell, W.R.1
Lockhart, J.C.2
Kelso, E.B.3
-
20
-
-
0035923526
-
Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis
-
Fiorucci S, Mencarelli A, Palazzetti B et al. Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis. Proc Natl Acad Sci U S A 2001: 98: 13936-13941.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13936-13941
-
-
Fiorucci, S.1
Mencarelli, A.2
Palazzetti, B.3
-
21
-
-
2942590747
-
Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis
-
Namkung W, Han W, Luo X et al. Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis. Gastroenterology 2004: 126: 1844-1859.
-
(2004)
Gastroenterology
, vol.126
, pp. 1844-1859
-
-
Namkung, W.1
Han, W.2
Luo, X.3
-
23
-
-
33745398503
-
Innate immune defects in atopic dermatitis
-
McGirt L Y, Beck L A. Innate immune defects in atopic dermatitis. J Allergy Clin Immunol 2006: 118: 202-208.
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 202-208
-
-
McGirt, L.Y.1
Beck, L.A.2
-
24
-
-
2342495351
-
Interferon-gamma activation of polymorphonuclear neutrophil function
-
Ellis T N, Beaman B L. Interferon-gamma activation of polymorphonuclear neutrophil function. Immunology 2004: 112: 2-12.
-
(2004)
Immunology
, vol.112
, pp. 2-12
-
-
Ellis, T.N.1
Beaman, B.L.2
-
25
-
-
30144440056
-
Interferon-activated neutrophils store a TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) intracellular pool that is readily mobilizable following exposure to proinflammatory mediators
-
Cassatella M A, Huber V, Calzetti F et al. Interferon-activated neutrophils store a TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) intracellular pool that is readily mobilizable following exposure to proinflammatory mediators. J Leukoc Biol 2006: 79: 123-132.
-
(2006)
J Leukoc Biol
, vol.79
, pp. 123-132
-
-
Cassatella, M.A.1
Huber, V.2
Calzetti, F.3
-
26
-
-
0842266786
-
Interferon-gamma: An overview of signals, mechanisms and functions
-
Schroder K, Hertzog P J, Ravasi T, Hume D A. Interferon-gamma: An overview of signals, mechanisms and functions. J Leukoc Biol 2004: 75: 163-189.
-
(2004)
J Leukoc Biol
, vol.75
, pp. 163-189
-
-
Schroder, K.1
Hertzog, P.J.2
Ravasi, T.3
Hume, D.A.4
-
27
-
-
33745266148
-
Immune response modifiers-mode of action
-
Schiller M, Metze D, Luger T A, Grabbe S, Gunzer M. Immune response modifiers-mode of action. Exp Dermatol 2006: 15: 331-341.
-
(2006)
Exp Dermatol
, vol.15
, pp. 331-341
-
-
Schiller, M.1
Metze, D.2
Luger, T.A.3
Grabbe, S.4
Gunzer, M.5
-
28
-
-
0037090339
-
Clinical trials of immunomodulatory therapies in severe sepsis and septic shock
-
Vincent J L, Sun Q, Dubois M J. Clinical trials of immunomodulatory therapies in severe sepsis and septic shock. Clin Infect Dis 2002: 34: 1084-1093.
-
(2002)
Clin Infect Dis
, vol.34
, pp. 1084-1093
-
-
Vincent, J.L.1
Sun, Q.2
Dubois, M.J.3
-
29
-
-
3442880113
-
Agonists of proteinase-activated receptor-2 modulate human neutrophil cytokine secretion, expression of cell adhesion molecules, and migration within 3-D collagen lattices
-
Shpacovitch V M, Varga G, Strey A et al. Agonists of proteinase-activated receptor-2 modulate human neutrophil cytokine secretion, expression of cell adhesion molecules, and migration within 3-D collagen lattices. J Leukoc Biol 2004: 76: 388-398.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 388-398
-
-
Shpacovitch, V.M.1
Varga, G.2
Strey, A.3
-
30
-
-
0034119167
-
Neutrophils: Molecules, functions and pathophysiological aspects
-
Witko-Sarsat V, Rieu P, Descamps-Latscha B, Lesavre P, Halbwachs-Mecarelli L. Neutrophils: Molecules, functions and pathophysiological aspects. Lab Invest 2000: 80: 617-653.
-
(2000)
Lab Invest
, vol.80
, pp. 617-653
-
-
Witko-Sarsat, V.1
Rieu, P.2
Descamps-Latscha, B.3
Lesavre, P.4
Halbwachs-Mecarelli, L.5
-
32
-
-
0036174696
-
Agonists of proteinase-activated receptor 2 induce cytokine release and activation of nuclear transcription factor kappaB in human dermal microvascular endothelial cells
-
Shpacovitch V M, Brzoska T, Buddenkotte J et al. Agonists of proteinase-activated receptor 2 induce cytokine release and activation of nuclear transcription factor kappaB in human dermal microvascular endothelial cells. J Invest Dermatol 2002: 118: 380-385.
-
(2002)
J Invest Dermatol
, vol.118
, pp. 380-385
-
-
Shpacovitch, V.M.1
Brzoska, T.2
Buddenkotte, J.3
-
33
-
-
0032560576
-
Proteinase-activated receptor 2 (PAR2)-activating peptides: Identification of a receptor distinct from PAR2 that regulates intestinal transport
-
Vergnolle N, Macnaughton W K, Al-Ani B, Saifeddine M, Wallace J L, Hollenberg M D. Proteinase-activated receptor 2 (PAR2)-activating peptides: Identification of a receptor distinct from PAR2 that regulates intestinal transport. Proc Natl Acad Sci U S A 1998: 95: 7766-7771.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7766-7771
-
-
Vergnolle, N.1
Macnaughton, W.K.2
Al-Ani, B.3
Saifeddine, M.4
Wallace, J.L.5
Hollenberg, M.D.6
-
34
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
-
Bone R C, Balk R A, Cerra F B et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992: 101: 1644-1655.
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
-
35
-
-
0019979966
-
Purification of human blood monocytes by hypotonic density gradient centrifugation in Percoll
-
Feige U, Overwien B, Sorg C. Purification of human blood monocytes by hypotonic density gradient centrifugation in Percoll. J Immunol Methods 1982: 54: 309-315.
-
(1982)
J Immunol Methods
, vol.54
, pp. 309-315
-
-
Feige, U.1
Overwien, B.2
Sorg, C.3
-
36
-
-
0031041789
-
Immunosurveillance modelled in vitro: Naive and memory T cells spontaneously migrate across unstimulated microvascular endothelium
-
Rohnelt R K, Hoch G, Reiss Y, Engelhardt B. Immunosurveillance modelled in vitro: Naive and memory T cells spontaneously migrate across unstimulated microvascular endothelium. Int Immunol 1997: 9: 435-450.
-
(1997)
Int Immunol
, vol.9
, pp. 435-450
-
-
Rohnelt, R.K.1
Hoch, G.2
Reiss, Y.3
Engelhardt, B.4
-
37
-
-
0028942106
-
Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro
-
Homburg C H, de Haas M, von dem Borne A E, Verhoeven A J, Reutelingsperger C P, Roos D. Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro. Blood 1995: 85: 532-540.
-
(1995)
Blood
, vol.85
, pp. 532-540
-
-
Homburg, C.H.1
de Haas, M.2
von dem Borne, A.E.3
Verhoeven, A.J.4
Reutelingsperger, C.P.5
Roos, D.6
-
38
-
-
0026795415
-
Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products
-
Colotta F, Re F, Polentarutti N, Sozzani S, Mantovani A. Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood 1992: 80: 2012-2020.
-
(1992)
Blood
, vol.80
, pp. 2012-2020
-
-
Colotta, F.1
Re, F.2
Polentarutti, N.3
Sozzani, S.4
Mantovani, A.5
-
39
-
-
15844401726
-
The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor
-
Nystedt S, Ramakrishnan V, Sundelin J. The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor. J Biol Chem 1996: 271: 14910-14915.
-
(1996)
J Biol Chem
, vol.271
, pp. 14910-14915
-
-
Nystedt, S.1
Ramakrishnan, V.2
Sundelin, J.3
-
40
-
-
1842782996
-
Anti-inflammatory properties of pro-inflammatory interferon-gamma
-
Muhl H, Pfeilschifter J. Anti-inflammatory properties of pro-inflammatory interferon-gamma. Int Immunopharmacol 2003: 3: 1247-1255.
-
(2003)
Int Immunopharmacol
, vol.3
, pp. 1247-1255
-
-
Muhl, H.1
Pfeilschifter, J.2
-
41
-
-
0034624973
-
Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
-
Camerer E, Huang W, Coughlin S R. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci U S A 2000: 97: 5255-5260.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5255-5260
-
-
Camerer, E.1
Huang, W.2
Coughlin, S.R.3
-
42
-
-
0037013268
-
Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells
-
Camerer E, Kataoka H, Kahn M, Lease K, Coughlin S R. Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells. J Biol Chem 2002: 277: 16081-16087.
-
(2002)
J Biol Chem
, vol.277
, pp. 16081-16087
-
-
Camerer, E.1
Kataoka, H.2
Kahn, M.3
Lease, K.4
Coughlin, S.R.5
-
43
-
-
0037303494
-
Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas
-
Jin E, Fujiwara M, Pan X et al. Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas. Cancer 2003: 97: 703-713.
-
(2003)
Cancer
, vol.97
, pp. 703-713
-
-
Jin, E.1
Fujiwara, M.2
Pan, X.3
-
45
-
-
0033832306
-
Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature
-
Wagner J G, Roth R A. Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature. Pharmacol Rev 2000: 52: 349-374.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 349-374
-
-
Wagner, J.G.1
Roth, R.A.2
-
46
-
-
0028182476
-
Mechanisms of neutrophil-dependent and neutrophil-independent endothelial cell injury
-
Varani J, Ward P A. Mechanisms of neutrophil-dependent and neutrophil-independent endothelial cell injury. Biol Signals 1994: 3: 1-14.
-
(1994)
Biol Signals
, vol.3
, pp. 1-14
-
-
Varani, J.1
Ward, P.A.2
-
47
-
-
0034050430
-
Regulation of inflammatory vascular damage
-
Lentsch A B, Ward P A. Regulation of inflammatory vascular damage. J Pathol 2000: 190: 343-348.
-
(2000)
J Pathol
, vol.190
, pp. 343-348
-
-
Lentsch, A.B.1
Ward, P.A.2
-
48
-
-
0031004487
-
Apoptosis in resolution of inflammation
-
Savill J. Apoptosis in resolution of inflammation. J Leukoc Biol 1997: 61: 375-380.
-
(1997)
J Leukoc Biol
, vol.61
, pp. 375-380
-
-
Savill, J.1
-
50
-
-
0026538793
-
Increase in neutrophil Fc gamma receptor I expression following interferon gamma treatment in rheumatoid arthritis
-
Goulding N J, Knight S M, Godolphin J L, Guyre P M. Increase in neutrophil Fc gamma receptor I expression following interferon gamma treatment in rheumatoid arthritis. Ann Rheum Dis 1992: 51: 465-468.
-
(1992)
Ann Rheum Dis
, vol.51
, pp. 465-468
-
-
Goulding, N.J.1
Knight, S.M.2
Godolphin, J.L.3
Guyre, P.M.4
-
51
-
-
33646677278
-
Neutrophil CD64 is an improved indicator of infection or sepsis in emergency department patients
-
Davis B H, Olsen S H, Ahmad E, Bigelow N C. Neutrophil CD64 is an improved indicator of infection or sepsis in emergency department patients. Arch Pathol Lab Med 2006: 130: 654-661.
-
(2006)
Arch Pathol Lab Med
, vol.130
, pp. 654-661
-
-
Davis, B.H.1
Olsen, S.H.2
Ahmad, E.3
Bigelow, N.C.4
-
52
-
-
34548511690
-
Inflammation
-
In: Burns T, Breathnach S, Cox N, Griffiths C, eds. 7th edn. Oxford: Blackwell Publishing Ltd
-
Steinhoff M, Griffiths C M E, Church M K, Luger T A. Inflammation. In: Burns T, Breathnach S, Cox N, Griffiths C, eds. Rook's Textbook of Dermatology, 7th edn. Oxford: Blackwell Publishing Ltd., 2004.
-
(2004)
Rook's Textbook of Dermatology
-
-
Steinhoff, M.1
Griffiths, C.M.E.2
Church, M.K.3
Luger, T.A.4
|