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Obesity in childhood and cardiovascular risk
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A recent review of trends and predictors of obesity and the metabolic syndrome in children
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Burke V. Obesity in childhood and cardiovascular risk. Clin Exp Pharmacol Physiol 2006; 33:831-837. A recent review of trends and predictors of obesity and the metabolic syndrome in children.
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Clin Exp Pharmacol Physiol
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Burke, V.1
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Pediatric obesity and insulin resistance: Chronic disease risk and implications for treatment beyond body weight
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Cruz ML, Shaibi GQ, Weigensberg MJ, et al. Pediatric obesity and insulin resistance: chronic disease risk and implications for treatment beyond body weight. Annu Rev Nutr 2005; 25:435-468.
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Kaufan FR. Obesity and type 2 diabetes in children and youth. Curr Opin Endocrinol Diabetes 2006; 13:332-337. A recent review of the literature on type 2 diabetes in children, risk factors, diagnosis and management.
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Kaufan FR. Obesity and type 2 diabetes in children and youth. Curr Opin Endocrinol Diabetes 2006; 13:332-337. A recent review of the literature on type 2 diabetes in children, risk factors, diagnosis and management.
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de Onis M, Garza C, Onyango AW, Borghiz E. Comparison of the WHO Child Growth Standards and the CDC 2000 Growth Charts. J Nutr 2007; 137:144-148. A comparison of child growth using the Centers for Disease Control and Prevention and recent WHO growth charts highlights the growth curve standard in determining changing rates of growth in infancy.
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de Onis M, Garza C, Onyango AW, Borghiz E. Comparison of the WHO Child Growth Standards and the CDC 2000 Growth Charts. J Nutr 2007; 137:144-148. A comparison of child growth using the Centers for Disease Control and Prevention and recent WHO growth charts highlights the growth curve standard in determining changing rates of growth in infancy.
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5
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33750604987
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Obesity and inflammation in children
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A comprehensive recent review on obesity-related inflammation in children
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Schwarzenberg SJ, Sinaiko AR. Obesity and inflammation in children. Paediatr Resp Rev 2006; 7:239-246. A comprehensive recent review on obesity-related inflammation in children.
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Paediatr Resp Rev
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Schwarzenberg, S.J.1
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Frayn KN, Fielding BA, Karpe F. Adipose tissue fatty acid metabolism and cardiovascular disease. Curr Opin Lipidol 2005; 16:409-415.
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Frayn, K.N.1
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Singhal A. Nutritional interventions in infancy and childhood for prevention of atherosclerosis and the metabolic syndrome. In: Lucas A, Sampson HA (Eds.), Primary prevention in by nutrition intervention in infancy and childhood. Nestle Nutr Workshop Ser Pediatr Program 2006; 57:15-30. A recent review of the childhood origins of atherosclerosis, metabolic syndrome in childhood, and the concept of the early origins of adult disease.
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Singhal A. Nutritional interventions in infancy and childhood for prevention of atherosclerosis and the metabolic syndrome. In: Lucas A, Sampson HA (Eds.), Primary prevention in by nutrition intervention in infancy and childhood. Nestle Nutr Workshop Ser Pediatr Program 2006; 57:15-30. A recent review of the childhood origins of atherosclerosis, metabolic syndrome in childhood, and the concept of the early origins of adult disease.
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9
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33644848054
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Obesity and inflammation: Evidence for an elementary lesion
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This recent paper provides histological evidence of early adipocyte degeneration, macrophage accumulation and inflammation in the adipose tissue of obese children
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Sbarbati A, Osculati F, Silvagni D, et al. Obesity and inflammation: evidence for an elementary lesion. Pediatrics 2006; 117:220-223. This recent paper provides histological evidence of early adipocyte degeneration, macrophage accumulation and inflammation in the adipose tissue of obese children.
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Pediatrics
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Sbarbati, A.1
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Atabek ME, Pirgon O, Kivrak AS. Evidence for association between insulin resistance and premature carotid atherosclereosis in childhood obesity. Pediatr Res 2007; 61:345-349. This recent study shows the inverse assocaiton between carotid intima media thickness and measures of insulin sensitivity, but not traditional lipid risk factors or homocysteine in 50 obese children.
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Atabek ME, Pirgon O, Kivrak AS. Evidence for association between insulin resistance and premature carotid atherosclereosis in childhood obesity. Pediatr Res 2007; 61:345-349. This recent study shows the inverse assocaiton between carotid intima media thickness and measures of insulin sensitivity, but not traditional lipid risk factors or homocysteine in 50 obese children.
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11
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34248998173
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Development of insulin-resistance and its relation to diet in the obese child
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Canete R, Gil-Campos M, Aguilera CM, Gil A. Development of insulin-resistance and its relation to diet in the obese child. Eur J Nutr 2007; In press.
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Eur J Nutr
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Canete, R.1
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Gil, A.4
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12
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A pro-inflammatory state is detectable in obese children and is accompanied by functional and morphological vascular changes
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Kapiotis S, Holzer G, Schaller G, et al. A pro-inflammatory state is detectable in obese children and is accompanied by functional and morphological vascular changes. Arterioscler Thromb Vasc Biol 2006; 26:2541-2546.
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Kapiotis, S.1
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33847006604
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Review: Peroxisome proliferator-activated receptor γ and adipose tissue-understanding obesity-related changes in regulation of lipid and glucose metabolism
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A comprehensive, authoritative review on PPARγ in adipose tissue and the potential beneficial role of PPARγ activiation in regulating the secretion of adipokines and NEFAs from adipocytes and inflammatory mediators from macrophages
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Sharma AM, Staels B. Review: peroxisome proliferator-activated receptor γ and adipose tissue-understanding obesity-related changes in regulation of lipid and glucose metabolism. J Endocrinol Metab 2007; 92:386-395. A comprehensive, authoritative review on PPARγ in adipose tissue and the potential beneficial role of PPARγ activiation in regulating the secretion of adipokines and NEFAs from adipocytes and inflammatory mediators from macrophages.
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J Endocrinol Metab
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Sharma, A.M.1
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Trayhurn P. Adipocyte biology. Obesity Rev 2007; 8:41-44.
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Fain JN. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity primarily due to nonfat cells. Vitamin Horm 2006; 74:44-47.
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Fain, J.N.1
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Roles of skeletal muscle and peroxisome proliferator-activated receptors in the development and treatment of obesity
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A recent review of PPARs focusing particularly on the role of skeletal muscle in lipid metabolism
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Lopez-Soriano J, Chiellini C, Maffei M, et al. Roles of skeletal muscle and peroxisome proliferator-activated receptors in the development and treatment of obesity. Endocrine Rev 2006; 27:318-329. A recent review of PPARs focusing particularly on the role of skeletal muscle in lipid metabolism.
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Lopez-Soriano, J.1
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Intermuscular adipose tissue rivals visceral adipose tissue in independent associations with cardiovascular risk
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24 April, E-pub ahead of print. doi:10.1038/sj.ijo.0803621. This recent study showed that intramuscular adipose tissue is independently inversely related to fasting glucose, after controlling for adipose tissue in other sites
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Yim JE, Heshka S, Albu J, et al. Intermuscular adipose tissue rivals visceral adipose tissue in independent associations with cardiovascular risk. Int J Obes (Lond) 24 April 2007; E-pub ahead of print. doi:10.1038/sj.ijo.0803621. This recent study showed that intramuscular adipose tissue is independently inversely related to fasting glucose, after controlling for adipose tissue in other sites.
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Int J Obes (Lond)
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Yim, J.E.1
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34548331575
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Truncal fat in relation to total body fat: Influences of age, sex, ethnicity and fatness
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24 April, E-pub ahead of print. doi:10.1038/sj.ijo.0803624. A recent study demonstrating the effect of ethnicity on truncal fat accumulation
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Wu CH, Heshka S, Wang J, et al. Truncal fat in relation to total body fat: influences of age, sex, ethnicity and fatness. Int J Obes (Lond) 24 April 2007; E-pub ahead of print. doi:10.1038/sj.ijo.0803624. A recent study demonstrating the effect of ethnicity on truncal fat accumulation.
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Int J Obes (Lond)
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Wu, C.H.1
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19
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Innis SM. Perinatal biochemistry and physiology of long chain polyunsaturated fatty acids. J Pediatr 2003; 143 (Suppl 4):S1-S8.
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A recent review of the effects of maternal dietary fatty acids on essential fatty acid transfer to the infant before and after birth
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Innis SM. Human milk: maternal dietary lipids and infant development. Proc Br Nutr Soc 2007; 66:397-404. A recent review of the effects of maternal dietary fatty acids on essential fatty acid transfer to the infant before and after birth.
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Innis, S.M.1
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Goyens PL, Spiker ME, Zock PL, et al. Compartmental modeling to quantify alphalinolenic acid and conversion after longer term intake of multiple tracer boluses. J Lipid Res 2005; 46:1474-1483.
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Hussein N, Ah-Sing E, Wilkinson P, et al. Long-chain conversion of [IBC] linoleic acid and alpha linolenic acid in response to marked changes in other dietary intake in men. J Lipid Res 2005; 64:42-50.
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Liou A, King DJ, Zibrik D, Innis SM. Decreasing linoleic acid with constant alpha linoleic acid in dietary fats increases (n-3) polyunsaturated fatty acids in plasma phospholipids in healthy men. J Nutr 2007; 137:1-8. This randomized dietary intervention showed that decreasing linolenic acid intakes do not influence circulating arachidonic acid, but increases EPA.
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Liou A, King DJ, Zibrik D, Innis SM. Decreasing linoleic acid with constant alpha linoleic acid in dietary fats increases (n-3) polyunsaturated fatty acids in plasma phospholipids in healthy men. J Nutr 2007; 137:1-8. This randomized dietary intervention showed that decreasing linolenic acid intakes do not influence circulating arachidonic acid, but increases EPA.
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N-3 Polyunsaturated fatty acids, inflammation, and inflammatory disease
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Elias SL, Innis SM. Newborn infant plasma transconjugated linoleic, n-6 and n-3 fatty acids are related to maternal plasma fatty acids, length of gestation and birth weight and length. Am J Clin Nutr 2001; 73:804-814.
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Lombardo YB, Chicco AG. Effect of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans. A review. J Nutr Biochem 2006; 17:1-13. A recent review of studies on the effects of n-3 fatty acids from fish oil on high fat and sucrose-induced change in adipose and skeletal muscle, focusing on dyslipidemia, glucose homeostasis and insulin resistance.
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