메뉴 건너뛰기




Volumn 28, Issue 10, 2007, Pages 1082-1090

Antenatal Dexamethasone Treatment Leads to Changes in Gene Expression in a Murine Late Placenta

Author keywords

Antenatal steroids; Dexamethasone; Fetal growth; Microarrays; Placental gene expression

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 11BETA HYDROXYSTEROID DEHYDROGENASE 1; AQUAPORIN 5; BONE MORPHOGENETIC PROTEIN 4; COLONY STIMULATING FACTOR 1; COMPLEMENT COMPONENT C3; CYCLIN A2; CYCLIN B1; CYCLIN D2; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN F; CYCLINE; CYTOKERATIN 14; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR RECEPTOR; FATTY ACID TRANSPORTER; FATTY ACID TRANSPORTER 6; M PHASE PROTEIN KINASE; MATRILYSIN; PROTEIN KINASE; SODIUM CHLORIDE; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; THYROTROPIN RECEPTOR; TRYPTOPHAN HYDROXYLASE; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 34548412178     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2007.04.002     Document Type: Article
Times cited : (59)

References (52)
  • 1
    • 84921431375 scopus 로고    scopus 로고
    • Prophylactic corticosteroids for preterm birth
    • CD000065
    • Crowley P. Prophylactic corticosteroids for preterm birth. Cochrane Database Syst Rev (2000) CD000065
    • (2000) Cochrane Database Syst Rev
    • Crowley, P.1
  • 2
    • 0036231896 scopus 로고    scopus 로고
    • ACOG committee opinion: antenatal corticosteroid therapy for fetal maturation
    • Committee on Obstetric P. ACOG committee opinion: antenatal corticosteroid therapy for fetal maturation. Obstet Gynecol 99 (2002) 871-873
    • (2002) Obstet Gynecol , vol.99 , pp. 871-873
    • Committee on Obstetric, P.1
  • 3
    • 0029062607 scopus 로고
    • Antenatal steroids are associated with less need for blood pressure support in extremely premature infants
    • Moise A.A., Wearden M.E., Kozinetz C.A., Gest A.L., Welty S.E., and Hansen T.N. Antenatal steroids are associated with less need for blood pressure support in extremely premature infants. Pediatrics 95 (1995) 845-850
    • (1995) Pediatrics , vol.95 , pp. 845-850
    • Moise, A.A.1    Wearden, M.E.2    Kozinetz, C.A.3    Gest, A.L.4    Welty, S.E.5    Hansen, T.N.6
  • 4
    • 0034218286 scopus 로고    scopus 로고
    • Antenatal corticosteroids and outcome at 14 years of age in children with birth weight less than 1501 grams
    • Doyle L.W., Ford G.W., Rickards A.L., Kelly E.A., Davis N.M., Callanan C., et al. Antenatal corticosteroids and outcome at 14 years of age in children with birth weight less than 1501 grams. Pediatrics 106 (2000) E2
    • (2000) Pediatrics , vol.106
    • Doyle, L.W.1    Ford, G.W.2    Rickards, A.L.3    Kelly, E.A.4    Davis, N.M.5    Callanan, C.6
  • 5
    • 0034984413 scopus 로고    scopus 로고
    • Effects of antenatal corticosteroid administration on mortality and long-term morbidity in early preterm, growth-restricted infants
    • Schaap A.H., Wolf H., Bruinse H.W., Smolders-De Haas H., Van Ertbruggen I., and Treffers P.E. Effects of antenatal corticosteroid administration on mortality and long-term morbidity in early preterm, growth-restricted infants. Obstet Gynecol 97 (2001) 954-960
    • (2001) Obstet Gynecol , vol.97 , pp. 954-960
    • Schaap, A.H.1    Wolf, H.2    Bruinse, H.W.3    Smolders-De Haas, H.4    Van Ertbruggen, I.5    Treffers, P.E.6
  • 6
    • 0035130204 scopus 로고    scopus 로고
    • The effect of multidose antenatal betamethasone on maternal and infant outcomes
    • Thorp J.A., Jones A.M., Hunt C., and Clark R. The effect of multidose antenatal betamethasone on maternal and infant outcomes. Am J Obstet Gynecol 184 (2001) 196-202
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 196-202
    • Thorp, J.A.1    Jones, A.M.2    Hunt, C.3    Clark, R.4
  • 7
    • 0034830158 scopus 로고    scopus 로고
    • Multiple courses of antenatal steroids: risks and benefits
    • Walfisch A., Hallak M., and Mazor M. Multiple courses of antenatal steroids: risks and benefits. Obstet Gynecol 98 (2001) 491-497
    • (2001) Obstet Gynecol , vol.98 , pp. 491-497
    • Walfisch, A.1    Hallak, M.2    Mazor, M.3
  • 8
    • 0035740401 scopus 로고    scopus 로고
    • Antenatal glucocorticoids and growth: single versus multiple doses in animal and human studies
    • Newnham J.P., and Moss T.J. Antenatal glucocorticoids and growth: single versus multiple doses in animal and human studies. Semin Neonatol 6 (2001) 285-292
    • (2001) Semin Neonatol , vol.6 , pp. 285-292
    • Newnham, J.P.1    Moss, T.J.2
  • 9
    • 1442305206 scopus 로고    scopus 로고
    • Single versus weekly courses of antenatal corticosteroids in preterm premature rupture of membranes
    • Lee M.J., Davies J., Guinn D., Sullivan L., Atkinson M.W., McGregor S., et al. Single versus weekly courses of antenatal corticosteroids in preterm premature rupture of membranes. Obstet Gynecol 103 (2004) 274-281
    • (2004) Obstet Gynecol , vol.103 , pp. 274-281
    • Lee, M.J.1    Davies, J.2    Guinn, D.3    Sullivan, L.4    Atkinson, M.W.5    McGregor, S.6
  • 10
    • 0036147455 scopus 로고    scopus 로고
    • Does antenatal corticosteroid therapy affect birth weight and head circumference?
    • Thorp J.A., Jones P.G., Knox E., and Clark R.H. Does antenatal corticosteroid therapy affect birth weight and head circumference?. Obstet Gynecol 99 (2002) 101-108
    • (2002) Obstet Gynecol , vol.99 , pp. 101-108
    • Thorp, J.A.1    Jones, P.G.2    Knox, E.3    Clark, R.H.4
  • 11
    • 4043178535 scopus 로고    scopus 로고
    • Two-year infant neurodevelopmental outcome after single or multiple antenatal courses of corticosteroids to prevent complications of prematurity
    • Spinillo A., Viazzo F., Colleoni R., Chiara A., Maria Cerbo R., et al. Two-year infant neurodevelopmental outcome after single or multiple antenatal courses of corticosteroids to prevent complications of prematurity. Am J Obstet Gynecol 191 (2004) 217-224
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 217-224
    • Spinillo, A.1    Viazzo, F.2    Colleoni, R.3    Chiara, A.4    Maria Cerbo, R.5
  • 12
    • 6044247523 scopus 로고    scopus 로고
    • Glucocorticoid exposure in late gestation in the rat permanently programs gender-specific differences in adult cardiovascular and metabolic physiology
    • O'Regan D., Kenyon C.J., Seckl J.R., and Holmes M.C. Glucocorticoid exposure in late gestation in the rat permanently programs gender-specific differences in adult cardiovascular and metabolic physiology. Am J Physiol Endocrinol Metab 287 (2004) E863-E870
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • O'Regan, D.1    Kenyon, C.J.2    Seckl, J.R.3    Holmes, M.C.4
  • 13
    • 0030940457 scopus 로고    scopus 로고
    • Placental 11 beta-hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure
    • Benediktsson R., Calder A.A., Edwards C.R., and Seckl J.R. Placental 11 beta-hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure. Clin Endocrinol (Oxf) 46 (1997) 161-166
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 161-166
    • Benediktsson, R.1    Calder, A.A.2    Edwards, C.R.3    Seckl, J.R.4
  • 14
    • 0242720030 scopus 로고    scopus 로고
    • Glucocorticoid metabolism and reproduction: a tale of two enzymes
    • Michael A.E., Thurston L.M., and Rae M.T. Glucocorticoid metabolism and reproduction: a tale of two enzymes. Reproduction 126 (2003) 425-441
    • (2003) Reproduction , vol.126 , pp. 425-441
    • Michael, A.E.1    Thurston, L.M.2    Rae, M.T.3
  • 15
    • 0036882139 scopus 로고    scopus 로고
    • 11beta-hydroxysteroid dehydrogenase types 1 and 2: an important pharmacokinetic determinant for the activity of synthetic mineralo- and glucocorticoids
    • Diederich S., Eigendorff E., Burkhardt P., Quinkler M., Bumke-Vogt C., Rochel M., et al. 11beta-hydroxysteroid dehydrogenase types 1 and 2: an important pharmacokinetic determinant for the activity of synthetic mineralo- and glucocorticoids. J Clin Endocrinol Metab 87 (2002) 5695-5701
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5695-5701
    • Diederich, S.1    Eigendorff, E.2    Burkhardt, P.3    Quinkler, M.4    Bumke-Vogt, C.5    Rochel, M.6
  • 16
    • 0028986997 scopus 로고
    • Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis
    • Stewart P.M., Rogerson F.M., and Mason J.I. Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis. J Clin Endocrinol Metab 80 (1995) 885-890
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 885-890
    • Stewart, P.M.1    Rogerson, F.M.2    Mason, J.I.3
  • 17
    • 4043077286 scopus 로고    scopus 로고
    • 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response
    • Tomlinson J.W., Walker E.A., Bujalska I.J., Draper N., Lavery G.G., Cooper M.S., et al. 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Rev 25 (2004) 831-866
    • (2004) Endocr Rev , vol.25 , pp. 831-866
    • Tomlinson, J.W.1    Walker, E.A.2    Bujalska, I.J.3    Draper, N.4    Lavery, G.G.5    Cooper, M.S.6
  • 19
    • 8844256235 scopus 로고    scopus 로고
    • Steroid hormone synthesis in pregnancy
    • Kallen C.B. Steroid hormone synthesis in pregnancy. Obstet Gynecol Clin North Am 31 (2004) 795-816
    • (2004) Obstet Gynecol Clin North Am , vol.31 , pp. 795-816
    • Kallen, C.B.1
  • 20
    • 18844362084 scopus 로고    scopus 로고
    • Dexamethasone-induced intrauterine growth restriction impacts the placental prolactin family, insulin-like growth factor-II and the Akt signaling pathway
    • Ain R., Canham L.N., and Soares M.J. Dexamethasone-induced intrauterine growth restriction impacts the placental prolactin family, insulin-like growth factor-II and the Akt signaling pathway. J Endocrinol 185 (2005) 253-263
    • (2005) J Endocrinol , vol.185 , pp. 253-263
    • Ain, R.1    Canham, L.N.2    Soares, M.J.3
  • 22
    • 0033693329 scopus 로고    scopus 로고
    • Apoptosis in rat placenta is zone-dependent and stimulated by glucocorticoids
    • Waddell B.J., Hisheh S., Dharmarajan A.M., and Burton P.J. Apoptosis in rat placenta is zone-dependent and stimulated by glucocorticoids. Biol Reprod 63 (2000) 1913-1917
    • (2000) Biol Reprod , vol.63 , pp. 1913-1917
    • Waddell, B.J.1    Hisheh, S.2    Dharmarajan, A.M.3    Burton, P.J.4
  • 24
    • 29244448340 scopus 로고    scopus 로고
    • Microarray data analysis: from disarray to consolidation and consensus
    • Allison D.B., Cui X., Page G.P., and Sabripour M. Microarray data analysis: from disarray to consolidation and consensus. Nat Rev Genet 7 (2006) 55-65
    • (2006) Nat Rev Genet , vol.7 , pp. 55-65
    • Allison, D.B.1    Cui, X.2    Page, G.P.3    Sabripour, M.4
  • 25
    • 12344270322 scopus 로고    scopus 로고
    • Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes
    • de Kok J.B., Roelofs R.W., Giesendorf B.A., Pennings J.L., Waas E.T., Feuth T., et al. Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes. Lab Invest 85 (2005) 154-159
    • (2005) Lab Invest , vol.85 , pp. 154-159
    • de Kok, J.B.1    Roelofs, R.W.2    Giesendorf, B.A.3    Pennings, J.L.4    Waas, E.T.5    Feuth, T.6
  • 26
    • 29644435407 scopus 로고    scopus 로고
    • Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2)
    • Srinivas S.R., Gopal E., Zhuang L., Itagaki S., Martin P.M., Fei Y.J., et al. Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2). Biochem J 392 (2005) 655-664
    • (2005) Biochem J , vol.392 , pp. 655-664
    • Srinivas, S.R.1    Gopal, E.2    Zhuang, L.3    Itagaki, S.4    Martin, P.M.5    Fei, Y.J.6
  • 27
    • 0037987795 scopus 로고    scopus 로고
    • Antenatal corticosteroids-current thinking
    • Crowley P. Antenatal corticosteroids-current thinking. Bjog 110 Suppl. 20 (2003) 77-78
    • (2003) Bjog , vol.110 , Issue.SUPPL. 20 , pp. 77-78
    • Crowley, P.1
  • 28
    • 0038687179 scopus 로고    scopus 로고
    • Repeated courses of antenatal corticosteroids: is it justified?
    • Leung T.N., Lam P.M., Ng P.C., and Lau T.K. Repeated courses of antenatal corticosteroids: is it justified?. Acta Obstet Gynecol Scand 82 (2003) 589-596
    • (2003) Acta Obstet Gynecol Scand , vol.82 , pp. 589-596
    • Leung, T.N.1    Lam, P.M.2    Ng, P.C.3    Lau, T.K.4
  • 30
    • 0022621357 scopus 로고
    • Effects of antenatal steroid therapy on mortality and morbidity in very low birth weight infants
    • Doyle L.W., Kitchen W.H., Ford G.W., Rickards A.L., Lissenden J.V., and Ryan M.M. Effects of antenatal steroid therapy on mortality and morbidity in very low birth weight infants. J Pediatr 108 (1986) 287-292
    • (1986) J Pediatr , vol.108 , pp. 287-292
    • Doyle, L.W.1    Kitchen, W.H.2    Ford, G.W.3    Rickards, A.L.4    Lissenden, J.V.5    Ryan, M.M.6
  • 31
    • 0036260989 scopus 로고    scopus 로고
    • Long-term cognitive benefits of antenatal corticosteroids for prematurely born children with cranial ultrasound abnormalities
    • Arad I., Durkin M.S., Hinton V.J., Kuhn L., Chiriboga C., Kuban K., et al. Long-term cognitive benefits of antenatal corticosteroids for prematurely born children with cranial ultrasound abnormalities. Am J Obstet Gynecol 186 (2002) 818-825
    • (2002) Am J Obstet Gynecol , vol.186 , pp. 818-825
    • Arad, I.1    Durkin, M.S.2    Hinton, V.J.3    Kuhn, L.4    Chiriboga, C.5    Kuban, K.6
  • 32
    • 0842281793 scopus 로고    scopus 로고
    • Effects of three courses of maternally administered dexamethasone at 0.7, 0.75, and 0.8 of gestation on prenatal and postnatal growth in sheep
    • Kutzler M.A., Ruane E.K., Coksaygan T., Vincent S.E., and Nathanielsz P.W. Effects of three courses of maternally administered dexamethasone at 0.7, 0.75, and 0.8 of gestation on prenatal and postnatal growth in sheep. Pediatrics 113 (2004) 313-319
    • (2004) Pediatrics , vol.113 , pp. 313-319
    • Kutzler, M.A.1    Ruane, E.K.2    Coksaygan, T.3    Vincent, S.E.4    Nathanielsz, P.W.5
  • 33
    • 16244379220 scopus 로고    scopus 로고
    • Developmental consequences of antenatal dexamethasone treatment in nonhuman primates
    • Coe C.L., and Lubach G.R. Developmental consequences of antenatal dexamethasone treatment in nonhuman primates. Neurosci Biobehav Rev 29 (2005) 227-235
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 227-235
    • Coe, C.L.1    Lubach, G.R.2
  • 36
    • 10344226154 scopus 로고    scopus 로고
    • Prenatal glucocorticoids and long-term programming
    • Seckl J.R. Prenatal glucocorticoids and long-term programming. Eur J Endocrinol 151 Suppl. 3 (2004) U49-U62
    • (2004) Eur J Endocrinol , vol.151 , Issue.SUPPL. 3
    • Seckl, J.R.1
  • 37
    • 0036365762 scopus 로고    scopus 로고
    • Comparative developmental anatomy of the murine and human definitive placentae
    • Georgiades P., Ferguson-Smith A.C., and Burton G.J. Comparative developmental anatomy of the murine and human definitive placentae. Placenta 23 (2002) 3-19
    • (2002) Placenta , vol.23 , pp. 3-19
    • Georgiades, P.1    Ferguson-Smith, A.C.2    Burton, G.J.3
  • 38
    • 0017337578 scopus 로고
    • In vitro metabolism of prednisolone, dexamethasone, betamethasone, and cortisol by the human placenta
    • Blanford A.T., and Murphy B.E. In vitro metabolism of prednisolone, dexamethasone, betamethasone, and cortisol by the human placenta. Am J Obstet Gynecol 127 (1977) 264-267
    • (1977) Am J Obstet Gynecol , vol.127 , pp. 264-267
    • Blanford, A.T.1    Murphy, B.E.2
  • 41
    • 0037224484 scopus 로고    scopus 로고
    • Nongenomic actions of steroid hormones
    • Losel R., and Wehling M. Nongenomic actions of steroid hormones. Nat Rev Mol Cell Biol 4 (2003) 46-56
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 46-56
    • Losel, R.1    Wehling, M.2
  • 42
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the cell cycle: cyclins revisited
    • Murray A.W. Recycling the cell cycle: cyclins revisited. Cell 116 (2004) 221-234
    • (2004) Cell , vol.116 , pp. 221-234
    • Murray, A.W.1
  • 43
    • 30944440763 scopus 로고    scopus 로고
    • Cyclins: roles in mitogenic signaling and oncogenic transformation
    • Musgrove E.A. Cyclins: roles in mitogenic signaling and oncogenic transformation. Growth Factors 24 (2006) 13-19
    • (2006) Growth Factors , vol.24 , pp. 13-19
    • Musgrove, E.A.1
  • 44
    • 27144522561 scopus 로고    scopus 로고
    • Uteroplacental insufficiency alters hepatic expression, phosphorylation, and activity of the glucocorticoid receptor in fetal IUGR rats
    • Baserga M., Hale M.A., McKnight R.A., Yu X., Callaway C.W., and Lane R.H. Uteroplacental insufficiency alters hepatic expression, phosphorylation, and activity of the glucocorticoid receptor in fetal IUGR rats. Am J Physiol Regul Integr Comp Physiol 289 (2005) R1348-R1353
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289
    • Baserga, M.1    Hale, M.A.2    McKnight, R.A.3    Yu, X.4    Callaway, C.W.5    Lane, R.H.6
  • 45
    • 1542344329 scopus 로고    scopus 로고
    • Cyclin F disruption compromises placental development and affects normal cell cycle execution
    • Tetzlaff M.T., Bai C., Finegold M., Wilson J., Harper J.W., Mahon K.A., et al. Cyclin F disruption compromises placental development and affects normal cell cycle execution. Mol Cell Biol 24 (2004) 2487-2498
    • (2004) Mol Cell Biol , vol.24 , pp. 2487-2498
    • Tetzlaff, M.T.1    Bai, C.2    Finegold, M.3    Wilson, J.4    Harper, J.W.5    Mahon, K.A.6
  • 46
    • 28844503868 scopus 로고    scopus 로고
    • The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy
    • Straszewski-Chavez S.L., Abrahams V.M., and Mor G. The role of apoptosis in the regulation of trophoblast survival and differentiation during pregnancy. Endocr Rev 26 (2005) 877-897
    • (2005) Endocr Rev , vol.26 , pp. 877-897
    • Straszewski-Chavez, S.L.1    Abrahams, V.M.2    Mor, G.3
  • 47
    • 33644799024 scopus 로고    scopus 로고
    • Signal transduction pathways involved in oxidative stress-induced intestinal epithelial cell apoptosis
    • Zhou Y., Wang Q., Evers B.M., and Chung D.H. Signal transduction pathways involved in oxidative stress-induced intestinal epithelial cell apoptosis. Pediatr Res 58 (2005) 1192-1197
    • (2005) Pediatr Res , vol.58 , pp. 1192-1197
    • Zhou, Y.1    Wang, Q.2    Evers, B.M.3    Chung, D.H.4
  • 48
    • 0035065666 scopus 로고    scopus 로고
    • Early growth retardation induced by excessive exposure to glucocorticoids in utero selectively increases cardiac GLUT1 protein expression and Akt/protein kinase B activity in adulthood
    • Langdown M.L., Holness M.J., and Sugden M.C. Early growth retardation induced by excessive exposure to glucocorticoids in utero selectively increases cardiac GLUT1 protein expression and Akt/protein kinase B activity in adulthood. J Endocrinol 169 (2001) 11-22
    • (2001) J Endocrinol , vol.169 , pp. 11-22
    • Langdown, M.L.1    Holness, M.J.2    Sugden, M.C.3
  • 49
    • 0035798592 scopus 로고    scopus 로고
    • Aquaporin-5 dependent fluid secretion in airway submucosal glands
    • Song Y., and Verkman A.S. Aquaporin-5 dependent fluid secretion in airway submucosal glands. J Biol Chem 276 (2001) 41288-41292
    • (2001) J Biol Chem , vol.276 , pp. 41288-41292
    • Song, Y.1    Verkman, A.S.2
  • 50
    • 18844405152 scopus 로고    scopus 로고
    • 5-HT in systemic hypertension: foe, friend or fantasy?
    • Watts S.W. 5-HT in systemic hypertension: foe, friend or fantasy?. Clin Sci (Lond) 108 (2005) 399-412
    • (2005) Clin Sci (Lond) , vol.108 , pp. 399-412
    • Watts, S.W.1
  • 51
    • 25844526295 scopus 로고    scopus 로고
    • Fluoxetine during pregnancy: impact on fetal development
    • Morrison J.L., Riggs K.W., and Rurak D.W. Fluoxetine during pregnancy: impact on fetal development. Reprod Fertil Dev 17 (2005) 641-650
    • (2005) Reprod Fertil Dev , vol.17 , pp. 641-650
    • Morrison, J.L.1    Riggs, K.W.2    Rurak, D.W.3
  • 52
    • 33646530739 scopus 로고    scopus 로고
    • Prenatal programming of hepatocyte nuclear factor 4alpha in the rat: a key mechanism in the 'fetal origins of hyperglycaemia'?
    • Nyirenda M.J., Dean S., Lyons V., Chapman K.E., and Seckl J.R. Prenatal programming of hepatocyte nuclear factor 4alpha in the rat: a key mechanism in the 'fetal origins of hyperglycaemia'?. Diabetologia 49 (2006) 1412-1420
    • (2006) Diabetologia , vol.49 , pp. 1412-1420
    • Nyirenda, M.J.1    Dean, S.2    Lyons, V.3    Chapman, K.E.4    Seckl, J.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.