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Volumn 7, Issue , 2007, Pages

Overexpressed TP73 induces apoptosis in medulloblastoma

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; PROTEIN P73; RNA; DNA BINDING PROTEIN; NUCLEAR PROTEIN; TP73 PROTEIN, HUMAN; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 34548354662     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-127     Document Type: Article
Times cited : (39)

References (55)
  • 2
    • 0036329571 scopus 로고    scopus 로고
    • Incidence and trends in pediatric malignancies medulloblastoma/primitive neuroectodermal tumor: A SEER update. Surveillance Epidemiology and End Results
    • 10.1002/mpo.10121 12210449
    • McNeil DE Cote TR Clegg L Rorke LB Incidence and trends in pediatric malignancies medulloblastoma/primitive neuroectodermal tumor: A SEER update. Surveillance Epidemiology and End Results Med Pediatr Oncol 2002 39 3 190-194 10.1002/mpo.10121 12210449
    • (2002) Med Pediatr Oncol , vol.39 , Issue.3 , pp. 190-194
    • McNeil, D.E.1    Cote, T.R.2    Clegg, L.3    Rorke, L.B.4
  • 3
    • 6344282578 scopus 로고    scopus 로고
    • Current treatment of medulloblastoma: Recent advances and future challenges
    • 10.1053/j.seminoncol.2004.07.009 15497120
    • Rood BR Macdonald TJ Packer RJ Current treatment of medulloblastoma: recent advances and future challenges Semin Oncol 2004 31 5 666-675 10.1053/j.seminoncol.2004.07.009 15497120
    • (2004) Semin Oncol , vol.31 , Issue.5 , pp. 666-675
    • Rood, B.R.1    Macdonald, T.J.2    Packer, R.J.3
  • 4
    • 0037222428 scopus 로고    scopus 로고
    • TP53 family members and human cancers
    • 10.1002/humu.10172 12619104
    • Benard J Douc-Rasy S Ahomadegbe JC TP53 family members and human cancers Hum Mutat 2003 21 3 182-191 10.1002/humu.10172 12619104
    • (2003) Hum Mutat , vol.21 , Issue.3 , pp. 182-191
    • Benard, J.1    Douc-Rasy, S.2    Ahomadegbe, J.C.3
  • 6
    • 0038075338 scopus 로고    scopus 로고
    • Decision making by p53: Life, death and cancer
    • 10.1038/sj.cdd.4401183 12719720
    • Oren M Decision making by p53: Life, death and cancer Cell Death Differ 2003 10 4 431-442 10.1038/sj.cdd.4401183 12719720
    • (2003) Cell Death Differ , vol.10 , Issue.4 , pp. 431-442
    • Oren, M.1
  • 9
    • 26844469719 scopus 로고    scopus 로고
    • Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus
    • 554768 15717928 10.1186/1471-2407-5-19
    • Eberhart CG Chaudhry A Daniel RW Khaki L Shah KV Gravitt PE Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus BMC Cancer 2005 5 19 554768 15717928 10.1186/1471-2407-5-19
    • (2005) BMC Cancer , vol.5 , pp. 19
    • Eberhart, C.G.1    Chaudhry, A.2    Daniel, R.W.3    Khaki, L.4    Shah, K.V.5    Gravitt, P.E.6
  • 10
    • 0035863498 scopus 로고    scopus 로고
    • Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched
    • 11212243
    • Wetmore C Eberhart DE Curran T Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched Cancer Res 2001 61 2 513-516 11212243
    • (2001) Cancer Res , vol.61 , Issue.2 , pp. 513-516
    • Wetmore, C.1    Eberhart, D.E.2    Curran, T.3
  • 11
    • 0033108219 scopus 로고    scopus 로고
    • Cytogenetics and molecular genetics of childhood brain tumors
    • 10.1215/15228517-1-2-139 11550309 1920753
    • Biegel JA Cytogenetics and molecular genetics of childhood brain tumors Neuro-oncol 1999 1 2 139-151 10.1215/15228517-1-2-139 11550309 1920753
    • (1999) Neuro-oncol , vol.1 , Issue.2 , pp. 139-151
    • Biegel, J.A.1
  • 12
    • 0036366824 scopus 로고    scopus 로고
    • Classifying the medulloblastoma: Insights from morphology and molecular genetics
    • 10.1046/j.1365-2990.2002.00419.x 12175339
    • Ellison D Classifying the medulloblastoma: Insights from morphology and molecular genetics Neuropathol Appl Neurobiol 2002 28 4 257-282 10.1046/ j.1365-2990.2002.00419.x 12175339
    • (2002) Neuropathol Appl Neurobiol , vol.28 , Issue.4 , pp. 257-282
    • Ellison, D.1
  • 14
    • 0034647718 scopus 로고    scopus 로고
    • An anti-apoptotic role for the p53 family member, p73, during developmental neuron death
    • 10.1126/science.289.5477.304 10894779
    • Pozniak CD Radinovic S Yang A McKeon F Kaplan DR Miller FD An anti-apoptotic role for the p53 family member, p73, during developmental neuron death Science 2000 289 5477 304-306 10.1126/science.289.5477.304 10894779
    • (2000) Science , vol.289 , Issue.5477 , pp. 304-306
    • Pozniak, C.D.1    Radinovic, S.2    Yang, A.3    McKeon, F.4    Kaplan, D.R.5    Miller, F.D.6
  • 15
    • 4544357676 scopus 로고    scopus 로고
    • Neuronal survival and p73/p63/p53: A family affair
    • 10.1177/1073858404263456 15359011
    • Jacobs WB Walsh GS Miller FD Neuronal survival and p73/p63/p53: A family affair Neuroscientist 2004 10 5 443-455 10.1177/1073858404263456 15359011
    • (2004) Neuroscientist , vol.10 , Issue.5 , pp. 443-455
    • Jacobs, W.B.1    Walsh, G.S.2    Miller, F.D.3
  • 16
    • 11144357549 scopus 로고    scopus 로고
    • Transdominant DeltaTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo
    • 10.1158/0008-5472.CAN-03-1060 15059898
    • Concin N Becker K Slade N Erster S Mueller-Holzner E Ulmer H Daxenbichler G Zeimet A Zeillinger R Marth C Moll UM Transdominant DeltaTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo Cancer Res 2004 64 7 2449-2460 10.1158/0008-5472.CAN-03-1060 15059898
    • (2004) Cancer Res , vol.64 , Issue.7 , pp. 2449-2460
    • Concin, N.1    Becker, K.2    Slade, N.3    Erster, S.4    Mueller-Holzner, E.5    Ulmer, H.6    Daxenbichler, G.7    Zeimet, A.8    Zeillinger, R.9    Marth, C.10    Moll, U.M.11
  • 19
    • 27644458185 scopus 로고    scopus 로고
    • Aberrant expression of DeltaNp73 in benign and malignant tumours of the prostate: Correlation with Gleason score
    • 10.1136/jcp.2005.026955 16254107
    • Guan M Chen Y Aberrant expression of DeltaNp73 in benign and malignant tumours of the prostate: Correlation with Gleason score J Clin Pathol 2005 58 11 1175-1179 10.1136/jcp.2005.026955 16254107
    • (2005) J Clin Pathol , vol.58 , Issue.11 , pp. 1175-1179
    • Guan, M.1    Chen, Y.2
  • 20
    • 0036468249 scopus 로고    scopus 로고
    • Possible oncogenic potential of DeltaNp73: A newly identified isoform of human p73
    • 11830511
    • Ishimoto O Kawahara C Enjo K Obinata M Nukiwa T Ikawa S Possible oncogenic potential of DeltaNp73: A newly identified isoform of human p73 Cancer Res 2002 62 3 636-641 11830511
    • (2002) Cancer Res , vol.62 , Issue.3 , pp. 636-641
    • Ishimoto, O.1    Kawahara, C.2    Enjo, K.3    Obinata, M.4    Nukiwa, T.5    Ikawa, S.6
  • 21
    • 0036628511 scopus 로고    scopus 로고
    • Transactivation-deficient DeltaTA-p73 acts as an oncogene
    • 12097259
    • Stiewe T Zimmermann S Frilling A Esche H Putzer BM Transactivation-deficient DeltaTA-p73 acts as an oncogene Cancer Res 2002 62 13 3598-3602 12097259
    • (2002) Cancer Res , vol.62 , Issue.13 , pp. 3598-3602
    • Stiewe, T.1    Zimmermann, S.2    Frilling, A.3    Esche, H.4    Putzer, B.M.5
  • 22
    • 0037119631 scopus 로고    scopus 로고
    • DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors
    • 10.1084/jem.20020179 12235210
    • Zaika AI Slade N Erster SH Sansome C Joseph TW Pearl M Chalas E Moll UM DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors J Exp Med 2002 196 6 765-780 10.1084/ jem.20020179 12235210
    • (2002) J Exp Med , vol.196 , Issue.6 , pp. 765-780
    • Zaika, A.I.1    Slade, N.2    Erster, S.H.3    Sansome, C.4    Joseph, T.W.5    Pearl, M.6    Chalas, E.7    Moll, U.M.8
  • 25
    • 0033108117 scopus 로고    scopus 로고
    • The treatment of malignant brain tumors in infants and very young children: An update of the Pediatric Oncology Group experience
    • 10.1215/15228517-1-2-152 11554387 1920752
    • Duffner PK Horowitz ME Krischer JP Burger PC Cohen ME Sanford RA Friedman HS Kun LE The treatment of malignant brain tumors in infants and very young children: An update of the Pediatric Oncology Group experience Neuro-oncol 1999 1 2 152-161 10.1215/15228517-1-2-152 11554387 1920752
    • (1999) Neuro-oncol , vol.1 , Issue.2 , pp. 152-161
    • Duffner, P.K.1    Horowitz, M.E.2    Krischer, J.P.3    Burger, P.C.4    Cohen, M.E.5    Sanford, R.A.6    Friedman, H.S.7    Kun, L.E.8
  • 27
    • 0035873928 scopus 로고    scopus 로고
    • Feasibility of four consecutive high-dose chemotherapy cycles with stem-cell rescue for patients with newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor after craniospinal radiotherapy: Results of a collaborative study
    • 11352962
    • Strother D Ashley D Kellie SJ Patel A Jones-Wallace D Thompson S Heideman R Benaim E Krance R Bowman L Gajjar A Feasibility of four consecutive high-dose chemotherapy cycles with stem-cell rescue for patients with newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor after craniospinal radiotherapy: Results of a collaborative study J Clin Oncol 2001 19 10 2696-2704 11352962
    • (2001) J Clin Oncol , vol.19 , Issue.10 , pp. 2696-2704
    • Strother, D.1    Ashley, D.2    Kellie, S.J.3    Patel, A.4    Jones-Wallace, D.5    Thompson, S.6    Heideman, R.7    Benaim, E.8    Krance, R.9    Bowman, L.10    Gajjar, A.11
  • 29
    • 34548340142 scopus 로고    scopus 로고
    • Sanger Center Cancer Cell Line Project
    • Sanger Center Cancer Cell Line Project http://www.sanger.ac.uk/genetics/ CGP/CellLines/
  • 30
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • 55695 11328886 10.1093/nar/29.9.e45
    • Pfaffl MW A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 2001 29 9 e45 55695 11328886 10.1093/ nar/29.9.e45
    • (2001) Nucleic Acids Res , vol.29 , Issue.9
    • Pfaffl, M.W.1
  • 34
    • 6944246205 scopus 로고    scopus 로고
    • Multiple stress signals induce p73beta accumulation
    • 1531659 15548364 10.1593/neo.04205
    • Lin KW Nam SY Toh WH Dulloo I Sabapathy K Multiple stress signals induce p73beta accumulation Neoplasia 2004 6 5 546-557 1531659 15548364 10.1593/ neo.04205
    • (2004) Neoplasia , vol.6 , Issue.5 , pp. 546-557
    • Lin, K.W.1    Nam, S.Y.2    Toh, W.H.3    Dulloo, I.4    Sabapathy, K.5
  • 35
    • 15444368415 scopus 로고    scopus 로고
    • New antibodies recognizing p73: Comparison with commercial antibodies
    • 10.1016/j.bbrc.2005.02.145 15781249
    • Sayan AE Paradisi A Vojtesek B Knight RA Melino G Candi E New antibodies recognizing p73: Comparison with commercial antibodies Biochem Biophys Res Commun 2005 330 1 186-193 10.1016/j.bbrc.2005.02.145 15781249
    • (2005) Biochem Biophys Res Commun , vol.330 , Issue.1 , pp. 186-193
    • Sayan, A.E.1    Paradisi, A.2    Vojtesek, B.3    Knight, R.A.4    Melino, G.5    Candi, E.6
  • 36
    • 34548342303 scopus 로고    scopus 로고
    • Brain Gene Expression Map
    • Brain Gene Expression Map http://www.stjudebgem.org/web/view/probe/ viewProbeDetails.php?id=2588
  • 37
    • 5644268982 scopus 로고    scopus 로고
    • Evidence that DeltaNp73 promotes neuronal survival by p53-dependent and p53-independent mechanisms
    • 10.1523/JNEUROSCI.1588-04.2004 15483136
    • Lee AF Ho DK Zanassi P Walsh GS Kaplan DR Miller FD Evidence that DeltaNp73 promotes neuronal survival by p53-dependent and p53-independent mechanisms J Neurosci 2004 24 41 9174-84 10.1523/ JNEUROSCI.1588-04.2004 15483136
    • (2004) J Neurosci , vol.24 , Issue.41 , pp. 9174-9184
    • Lee, A.F.1    Ho, D.K.2    Zanassi, P.3    Walsh, G.S.4    Kaplan, D.R.5    Miller, F.D.6
  • 39
    • 0033605725 scopus 로고    scopus 로고
    • p73 gene transcripts in human brain tumors: Overexpression and altered splicing in ependymomas
    • 10.1016/S0304-3940(99)00130-5 10213163
    • Loiseau H Arsaut J Demotes-Mainard J p73 gene transcripts in human brain tumors: Overexpression and altered splicing in ependymomas Neurosci Lett 1999 263 2-3 173-6 10.1016/S0304-3940(99)00130-5 10213163
    • (1999) Neurosci Lett , vol.263 , Issue.2-3 , pp. 173-176
    • Loiseau, H.1    Arsaut, J.2    Demotes-Mainard, J.3
  • 40
    • 0033168066 scopus 로고    scopus 로고
    • Overexpression of the wild type p73 gene in breast cancer tissues and cell lines
    • 10397274
    • Zaika AI Kovalev S Marchenko ND Moll UM Overexpression of the wild type p73 gene in breast cancer tissues and cell lines Cancer Res 1999 59 13 3257-63 10397274
    • (1999) Cancer Res , vol.59 , Issue.13 , pp. 3257-3263
    • Zaika, A.I.1    Kovalev, S.2    Marchenko, N.D.3    Moll, U.M.4
  • 41
    • 0033199166 scopus 로고    scopus 로고
    • Distinct expression patterns of the p53-homologue p73 in malignant and normal hematopoiesis assessed by a novel real-time reverse transcription-polymerase chain reaction assay and protein analysis
    • 10485463
    • Peters UR Tschan MP Kreuzer KA Baskaynak G Lass U Tobler A Fey MF Schmidt CA Distinct expression patterns of the p53-homologue p73 in malignant and normal hematopoiesis assessed by a novel real-time reverse transcription-polymerase chain reaction assay and protein analysis Cancer Res 1999 59 17 4233-6 10485463
    • (1999) Cancer Res , vol.59 , Issue.17 , pp. 4233-4236
    • Peters, U.R.1    Tschan, M.P.2    Kreuzer, K.A.3    Baskaynak, G.4    Lass, U.5    Tobler, A.6    Fey, M.F.7    Schmidt, C.A.8
  • 42
    • 0037096348 scopus 로고    scopus 로고
    • Expression of p73 and Reelin in the developing human cortex
    • 12077194
    • Meyer G Perez-Garcia CG Abraham H Caput D Expression of p73 and Reelin in the developing human cortex J Neurosci 2002 22 12 4973-86 12077194
    • (2002) J Neurosci , vol.22 , Issue.12 , pp. 4973-4986
    • Meyer, G.1    Perez-Garcia, C.G.2    Abraham, H.3    Caput, D.4
  • 43
    • 33645958875 scopus 로고    scopus 로고
    • Multiple isoforms of the tumor protein p73 are expressed in the adult human telencephalon and choroid plexus and present in the cerebrospinal fluid
    • 10.1111/j.1460-9568.2006.04750.x 16630058
    • Cabrera-Socorro A Pueyo Morlans M Suarez Sola ML Gonzalez Delgado FJ Castaneyra-Perdomo A Marin MC Meyer G Multiple isoforms of the tumor protein p73 are expressed in the adult human telencephalon and choroid plexus and present in the cerebrospinal fluid Eur J Neurosci 2006 23 8 2109-18 10.1111/j.1460-9568.2006.04750.x 16630058
    • (2006) Eur J Neurosci , vol.23 , Issue.8 , pp. 2109-2118
    • Cabrera-Socorro, A.1    Pueyo Morlans, M.2    Suarez Sola, M.L.3    Gonzalez Delgado, F.J.4    Castaneyra-Perdomo, A.5    Marin, M.C.6    Meyer, G.7
  • 46
    • 0037161921 scopus 로고    scopus 로고
    • DN-p73 is activated after DNA damage in a p53-dependent manner to regulate p53-induced cell cycle arrest
    • 10.1038/sj.onc.1205465 12032848
    • Vossio S Palescandolo E Pediconi N Moretti F Balsano C Levrero M Costanzo A DN-p73 is activated after DNA damage in a p53-dependent manner to regulate p53-induced cell cycle arrest Oncogene 2002 21 23 3796-3803 10.1038/sj.onc.1205465 12032848
    • (2002) Oncogene , vol.21 , Issue.23 , pp. 3796-3803
    • Vossio, S.1    Palescandolo, E.2    Pediconi, N.3    Moretti, F.4    Balsano, C.5    Levrero, M.6    Costanzo, A.7
  • 47
    • 33751185759 scopus 로고    scopus 로고
    • DeltaNp73: Misunderstood protein?
    • Epub 2006 Jul 14 16921261
    • Irwin MS DeltaNp73: Misunderstood protein? Cancer Biol Ther 2006 5 7 804-7 Epub 2006 Jul 14 16921261
    • (2006) Cancer Biol Ther , vol.5 , Issue.7 , pp. 804-807
    • Irwin, M.S.1
  • 48
    • 33751417425 scopus 로고    scopus 로고
    • Etoposide induces apoptosis and cell cycle arrest of neuroepithelial cells in a p53-related manner
    • 10.1016/j.ntt.2006.09.021 17095187
    • Nam C Yamauchi H Nakayama H Doi K Etoposide induces apoptosis and cell cycle arrest of neuroepithelial cells in a p53-related manner Neurotoxicol Teratol 2006 28 6 664-672 10.1016/j.ntt.2006.09.021 17095187
    • (2006) Neurotoxicol Teratol , vol.28 , Issue.6 , pp. 664-672
    • Nam, C.1    Yamauchi, H.2    Nakayama, H.3    Doi, K.4
  • 49
    • 0042674256 scopus 로고    scopus 로고
    • G2 arrest in response to topoisomerase II inhibitors: The role of p53
    • 12874009
    • Clifford B Beljin M Stark GR Taylor WR G2 arrest in response to topoisomerase II inhibitors: The role of p53 Cancer Res 2003 63 14 4074-4081 12874009
    • (2003) Cancer Res , vol.63 , Issue.14 , pp. 4074-4081
    • Clifford, B.1    Beljin, M.2    Stark, G.R.3    Taylor, W.R.4
  • 50
    • 1342343921 scopus 로고    scopus 로고
    • Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer
    • 10.1038/sj.onc.1207026 14749764
    • Attardi LD de Vries A Jacks T Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer Oncogene 2004 23 4 973-980 10.1038/sj.onc.1207026 14749764
    • (2004) Oncogene , vol.23 , Issue.4 , pp. 973-980
    • Attardi, L.D.1    de Vries, A.2    Jacks, T.3
  • 51
    • 0032951530 scopus 로고    scopus 로고
    • p73 function is inhibited by tumor-derived p53 mutants in mammalian cells
    • 116072 9891077
    • Di Como CJ Gaiddon C Prives C p73 function is inhibited by tumor-derived p53 mutants in mammalian cells Mol Cell Biol 1999 19 2 1438-1449 116072 9891077
    • (1999) Mol Cell Biol , vol.19 , Issue.2 , pp. 1438-1449
    • Di Como, C.J.1    Gaiddon, C.2    Prives, C.3
  • 53
    • 33744496269 scopus 로고    scopus 로고
    • MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis
    • Epub Feb 7 10.1182/blood-2005-07-2829 16467208
    • Lunghi P Costanzo A Salvatore L Noguera N Mazzera L Tabilio A Lo-Coco F Levrero M Bonati A MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis Blood 2006 107 11 4549-53 Epub 2006 Feb 7 10.1182/blood-2005-07-2829 16467208
    • (2006) Blood , vol.107 , Issue.11 , pp. 4549-4553
    • Lunghi, P.1    Costanzo, A.2    Salvatore, L.3    Noguera, N.4    Mazzera, L.5    Tabilio, A.6    Lo-Coco, F.7    Levrero, M.8    Bonati, A.9
  • 54
    • 0346725958 scopus 로고    scopus 로고
    • DeltaNp73beta is active in transactivation and growth suppression
    • 343790 14701724 10.1128/MCB.24.2.487-501.2004
    • Liu G Nozell S Xiao H Chen X DeltaNp73beta is active in transactivation and growth suppression Mol Cell Biol 2004 24 2 487-501 343790 14701724 10.1128/MCB.24.2.487-501.2004
    • (2004) Mol Cell Biol , vol.24 , Issue.2 , pp. 487-501
    • Liu, G.1    Nozell, S.2    Xiao, H.3    Chen, X.4
  • 55
    • 33751187878 scopus 로고    scopus 로고
    • Questioning the oncogenic role of DeltaNp73alpha in different cell lines expressing p53 or not
    • Epub 2006 Jul 28 16721041
    • Marrazzo E Marchini S Previdi S Broggini M Questioning the oncogenic role of DeltaNp73alpha in different cell lines expressing p53 or not Cancer Biol Ther 2006 5 7 794-803 Epub 2006 Jul 28 16721041
    • (2006) Cancer Biol Ther , vol.5 , Issue.7 , pp. 794-803
    • Marrazzo, E.1    Marchini, S.2    Previdi, S.3    Broggini, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.