Brain temperature fluctuations during physiological and pathological conditions

European Journal of Applied Physiology

Volumn 101, Issue 1, 2007, Pages 3-17

  Kiyatkin, Eugene A ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Addictive drugs; Brain edema; Brain metabolism; Hyperthermia; Neural activity; Neurotoxicity

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; BARBITURIC ACID DERIVATIVE; CATECHOL; METHAMPHETAMINE; NITRIC OXIDE; PENTOBARBITAL; PEROXYNITRITE; QUINONE DERIVATIVE;

ANESTHESIA INDUCTION; APOPTOSIS; BLOOD BRAIN BARRIER; BODY TEMPERATURE; BRAIN BLOOD FLOW; BRAIN DISEASE; BRAIN EDEMA; BRAIN FUNCTION; BRAIN METABOLISM; BRAIN TEMPERATURE; CELL METABOLISM; DRUG ABUSE; ENVIRONMENTAL FACTOR; HEAT TRANSFER; HUMAN; HYPERTHERMIA; MOTIVATION; NERVE CELL; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SEXUAL BEHAVIOR; SOCIAL INTERACTION; STIMULUS RESPONSE; THERMOGENESIS; THERMOREGULATION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BASAL METABOLISM; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; BRAIN; CEREBROVASCULAR CIRCULATION; COCAINE; DOPAMINE UPTAKE INHIBITORS; ENERGY TRANSFER; ENVIRONMENT; FEVER; HALLUCINOGENS; HEAT; HUMANS; LIMBIC SYSTEM; METHAMPHETAMINE;

EID: 34548222517     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-007-0450-7     Document Type: Review

References (121)

1. Abrams R, Hammel HT (1964) Hypothalamic temperature in unanesthetized albino rats during feeding and sleeping. Am J Physiol 206:641-646
2. Ali SF, Newport GD, Slikker W (1996) Methamphetamine-induced dopaminergic toxicity in mice: Role of environmental temperature and pharmacological agents. Ann NY Acad Sci 801:187-198
3. Arai H, Uto A, Ogawa Y, Sato K (1993) Effect of low temperature on glutamate-induced intracellular calcium accumulation and cell death in cultured hippocampal neurons. Neurosci Lett 163:132-134
4. Baker M, Cronin M, Mountjoy D (1976) Variability of skin temperature in the waking monkey. Am J Physiol 230:449-455
5. Berner NJ, Heller HC (1998) Does the preoptic anterior hypothalamus receive thermoafferent information? Am J Physiol 274:R9-R18
6. Blumberg MS, Mannella JA, Moltz H (1987) Hypothalamic temperature and deep body temperature during copulation in the male rat. Physiol Behav 39:367-370
7. Bohlen JG, Held JP, Sanderson MO, Patterson RP (1984) Heart rate, rate-pressure product and oxygen uptake during four sexual activities. Arch Intern Med 144:1745-1748
8. Boulant JA (2000) The role of preoptic-anterior hypothalamus in thermoregulation and fever. 31, Suppl 5:S157-S161
9. Bowyer JF, Ali S (2006) High doses of methamphetamine that cause disruption of the blood-brain barrier in limbic regions produce extensive neuronal degeneration in mouse hippocampus. Synapse 60:521-532
10. Brengelmann GL (1993) Specialized brain cooling in humans? FASEB J 7:1148-1153
11. Brown PL, Kiyatkin EA (2004) Brain hyperthermia induced by MDMA ("ecstasy"): Modulation by environmental conditions. Eur J Neurosci 20:51-58
12. Brown PL, Kiyatkin EA (2005) Fatal intra-brain heat accumulation induced by meth-amphetamine at normothermic conditions in rats. Intern J Neuroprot Neuroregen 1:86-90
13. Brown PL, Wise RA, Kiyatkin EA (2003) Brain hyperthermia is induced by methamphetamine and exacerbated by social interaction. J Neurosci 23:3924-3929
14. Burgoon PW, Boulant JA (2001) Temperature-sensitive properties of rat suprachiasmatic nucleus neurons. Am J Physiol 281:R706-R715
15. Busto R, Dietrich WD, Globus MYT, Valdes I, Scheinberg R, Ginsberg MD (1987) Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab 7:729-738
16. Cabanac M (1993) Selective brain cooling in humans: "fancy" or fact? FASEB J 7:1143-1147
17. Cadet JL, Thiriet N, Jayanthi S (2001) Involvement of free radicals in MDMA-induced neurotoxicity in mice. Ann Med Intern 152(Suppl. 3):IS57-IS59
18. Charkoudian N (2003) Skin blood flow in adult human thermoregulation: how it works, when it does not, and why? Mayo Clin Proc 78:603-612
19. Cheuvront SN, Haymes EM (2001) Thermoregulation and marathon running: biological and environmental influences. Sports Med 31:743-762
20. Crane P, Braun L, Cornford E, Cremer J, Glass J, Oldendorf M (1978) Dose-dependent reduction of glucose utilization by pentobarbital in rat brain. Stroke 9:12-18
21. Davidson C, Gow AJ, Lee TH, Ellinwood EH (2001) Methamphetamine neurotoxicity: Necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res Rev 36:1-22
22. Davis WM, Hatoum HT, Walters IW (1987) Toxicity of MDA (2,4-methylenedioxyamphetamine) considered for relevance to hazards of MDMA (ecstasy) abuse. Alcohol Drug Res 7:123-134
23. Delgado JMR, Hanai T (1966) Intracerebral temperatures in free-moving cats. Am J Physiol 211:755-769
24. Dewhirst MW, Viglianti BL, Lora-Michiels M, Hanson M, Hoopes PJ (2003) Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia. Int J Hyperthermia 19:267-294
25. Ecstasy and amphetamines. Global survey 2003. United Nations Publication, New York
26. Erikson K, Lanier W (2003) Anesthetic technique influences brain temperature, independently of core temperature, during craniotomy in cats. Anesth Analg 96:1460-1466
27. Feitelberg S, Lampl H (1935) Warmetonung der Grosshirnrinde bei Erregung und Ruhe. Functionshemmung Arch exp Path Pharmak 177:726-736
28. Fox RT, Raichle ME (1986) Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc Natl Acad Sci 83:1140-1144
29. Gerasimov V (1998) Information processing in human body. http://vadim.www.media.mit.edu/MAS862/Project.html
30. Goldfarg AN (1970) Energy cost of sexual activity. Arch Intern Med 126:526
31. Gordon CJ, Heath JE (1986) Integration and central processing in temperature regulation. Ann Rev Physiol 48:595-612
32. Gordon CJ, Watkinson WO, O'Callaghan JP, Miller DB (1991) Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat. Pharmacol Biochem Behav 38:339-344
33. Green AR, Mechan AO, Elliott JM, O'Shea E, Colado MI (2003) The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"). Pharmacol Rev 55:463-508
34. Guatteo E, Chung KK, Bowala TK, Bernardi G, Mercuri ND, Lipski J (2005) Temperature sensitivity of dopaminergic neurons of the substantia nigra pars compacta: Involvement of transient receptor potential; channels. J Neurophysiol 94:3069-3080
35. Hayward JN, Baker MA (1968) Role of cerebral arterial blood in the regulation of brain temperature in the monkey. Am J Physiol 215:389-403
36. Hodgkin AL (1967) The conduction of the nervous impulse. Liverpool University Press, Liverpool
37. Horvath TL, Warden CH, Hajos M, Lombardi A, Goglia F, Diano S (1999) Brain uncoupling protein 2: Uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers. J Neurosci 19:10417-10427
38. Ide K, Secher NH (2000) Cerebral blood flow and metabolism during exercise. Prog Neurobiol 61:397-414
39. Ide K, Schmalbruch IK, Quistorff B, Horn A, Secher NH (2000) Lactate, glucose, and oxygen uptake in human brain during recovery from maximal exercise. J Physiol 522:159-164
40. Iwagami Y (1996) Changes in ultrastructure of human cell related to certain biological responses under hyperthermic culture condition. Human Cell 9:353-366
41. James W (1892) Psychology. Briefer course. Henry Holt, New York
42. Kalant H (2001) The pharmacology and toxicology of "ecstasy" (MDMA) and related drugs. Can Med Assoc J 165:917-928
43. Katz B, Miledi R (1965) The effect of temperature on the synaptic delay at the neuromuscular junction. J Physiol 181:656-670
44. Kiyatkin EA (1988) Functional properties of presumed dopamine-containing and other ventral tegmental area neurons in conscious rats. Intern J Neurosci 42:21-43
45. Kiyatkin EA (2005) Brain hyperthermia as physiological and pathological phenomena. Brain Res Rev 50:27-56
46. Kiyatkin EA, Brown PL (2005) Brain and body temperature homeostasis during sodium pentobarbital anesthesia with and without body warming in rats. Physiol Behav 84:563-570
47. Kiyatkin EA, Mitchum R (2003) Fluctuations in brain temperatures during sexual behavior in male rats: An approach for evaluating neural activity underlying motivated behavior. Neuroscience 119:1169-1183
48. Kiyatkin EA, Stein EA (1993) Behavior-associated changes in blood pressure during heroin self-administration. Pharmacol Biochem Behav 46:561-567
49. Kiyatkin EA, Brown PL, Wise RA (2002) Brain temperature fluctuation: A reflection of functional neural activation. Eur J Neurosci 16:164-168
50. Kovalzon VM (1972) Brain temperature variations during natural sleep and arousal in white rats. Physiol Behav 10:667-670
51. Kuhn DM, Geddes TJ (2000) Molecular footprints of neurotoxic amphetamine action. Ann NY Acad Sci 914:92-103
52. Laughlin SB, de Ruyter van Steveninck RR, Anderson JC (1998) The metabolic cost of neural information. Nature Neurosci 1:36-41
53. Lee JCF, Callaway JC, Foehring RC (2005) The effects of temperature on calcium transients and Ca 2+ -dependent afterhyperpolarizations in neocortical pyramidal neurons. J Physiol 93:2012-2020
54. Lepock JR (2003) Cellular effects of hyperthermia: Relevance to the minimum dose for thermal damage. Int J Hyperthermia 19:252-266
55. Lepock JR, Cheng K-H, Al-Qysi H, Kruuv J (1983) Thermotropic lipid and protein transitions in Chinese hamster lung cell membranes: Relationship to hyperthermic cell killing. Can J Biochem Cell Biol 61:421-427
56. Lin PS, Quamo S, Ho KC, Gladding J (1991) Hyperthermia enhances the cytotoxic effects of reactive oxygen species to Chinese hamster cells and bovine endothelial cells in vitro. Radiat Med 126:43-51
57. Lucas JH, Emery DG, Wang G, Rosenberg-Schaffer LJ, Jordan RS, Gross GW (1994) In vitro investigation of the effect of nonfreezing low temperatures on leasoned and uninjured mammalian spinal neurons. J Neurotrauma 11:35-61
58. Lyson T, Jadeszko M, Mariak Z, Kochanowicz J, Lewko J (2006) Intracerebrain temperature measurements in brain death. Neurol Neurosurg Pol 40:269-275
59. Maier CM, Steinberg GK (2003) Hypothermia and cerebral ischemia. Humana Press, New York
60. Margaria R, Cretelli P, Aghemo P, Sassi G (1963) Energy cost of running. J Appl Physiol 18:367-370
61. Mariak Z, Lewko J, Luczaj J, Polocki B, White MD (1994) The relationship between directly measured human cerebral and tympanic temperatures during changes in brain temperature. Eur J Appl Physiol Occup Physiol 69:545-549
62. Mariak Z, Jadeszko M, Lewko J, Lebkowski W, Lyson T (1998) No specific brain protection against thermal stress in fever. Acta Neurochir (Wien) 140:585-590
63. Mariak Z, Lebkowski W, Lyson T, Lewko J, Piekarski P (1999) Brain temperature during craniotomy in general anesthesia. Neurol Neurochir Pol 33:1325-1327
64. Mariak Z, Lyson T, Peikarski P, Lewko J, Jadeszko M, Szydlik P (2000) Brain temperature in patients with central nervous system lesions. Neurol Neurosurg Pol 34:509-522
65. Masters WH, Johnson VE (1966) Human sexual response. Little, Brown and Co., Boston
66. McElligott JC, Melzack R (1967) Localized thermal changes evoked in the brain by visual and auditory stimulation. Exp Neurol 17:293-312
67. Mcilvoy L (2004) Comparison of brain temperature to core temperature: A review of the literature. J Neurosci Nurs 36:23-31
68. Mechan AO, O'Shea E, Elliot JM, Colado MI, Green AR (2001) A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long-term deficit in thermoregulation. Psychopharmacology 155:413-418
69. Mekjavic IB, Eiken O (2005) Contribution of thermal and nonthermal factors to the regulation of body temperature in mammals. J Appl Physiol 100:2065-2072
70. Mellergard P, Nordstrom CH (1990) Epidural temperatures and possible intracerebral temperature gradients in man. Br J Neurosurg 4:31-38
71. Michenfelder J (1988) Anesthesia and the brain: Clinical, functional and vascular correlates. Churchill Livingstone, New York
72. Mitchum R, Kiyatkin EA (2004) Brain hyperthermia and temperature fluctuations during sexual interaction in female rats. Brain Res 1000:110-122
73. Miyazawa T, Tamara A, Fukui S, Hossmann KA (2003) Effects of mild hypothermia on focal cerebral ischemia: Review of experimental studies. Neurol Res 25:457-464
74. Moriyama E (1990) Cerebral blood flow changes during localized hyperthermia. Neurol Med Chir (Tokio) 30:923-929
75. Moser E, Mathiesen L (1996) Relationships between neuronal activity and brain temperature in rats. Neuroreport 78:1876-1880
76. Moser E, Mathiesen I, Andersen P (1993) Association between brain temperature and dentate field potentials in exploring and swimming rats. Science 259:1324-1326
77. Nadel E (2003) Regulation of body temperature. In: Boron WF, Boulpaep EL (eds) Medical physiology. Saunders, Philadelphia, pp 1231-1241
78. Nagata Y, Katayama K, Manivel CJ, Song CW (2000) Changes in blood flow in locally heated intestine of rats. Int J Hyperthermia 16:159-170
79. Nakajima T, Rhee JG, Song CW, Onoyama Y (1992) Effect of a second heating on rat liver blood flow. Int J Hyperthermia 8:679-687
80. Nakashima K, Todd MM (1996) Effects of hypothermia on the rate of excitatory amino acid release after ischemic depolarization. Stroke 27:913-918
81. Nybo L, Secher NH, B. Nielson B (2002) Inadequate heat release from the human brain during prolonged exercise with hyperthermia. J Physiol 545:697-704
82. Olsen TS, Weber UJ, Kammersgaard LP (2003) Therapeutic hypothermia for acute stroke. Lancet Neurol 2:410-416
83. Oobu K (1993) Experimental studies on the effect of heating on blood flow in the tongue of golden hamsters Fukuoka Igaku Zasshi 84:497-511
84. Pederson NP, Blessing WW (2001) Cutaneous vasoconstriction contributes to hyperthermia induced by 3,4-methylenedioxymethamphetamine (ecstasy) on conscious rabbits. J Neurosci 21:8648-8654
85. Raichle ME (2003) Functional brain imaging and human brain functions J Neurosci 23:3959-3962
86. Ritchie JM (1973) Energetic aspects of nerve conduction: The relationships between heat production, electrical activity and metabolism. Prog Biophys Mol Biol 26:147-187
87. Romanovsky AA, Ivanov AI, Shimansky YP (2002) Ambient temperature for experiments in rats: A new method for determining the zone of thermal neutrality. J Appl Physiol 92:2667-2679
88. Rosomoff HL (1957) Hypothermia and cerebral varcular lesions. II. Experimental interruption followed by induction of hypothermia. Arch Neurol Psych 78:454-464
89. Rowell LB (1983) Cardiovascular aspects of human thermoregulation. Circ Res 52:367-376
90. Ruby NF, Heller HC (1996) Temperature sensitivity of the suprachiasmatic nucleus of ground squirrels and rats in vitro. J Biol Rhythms 11:126-136
91. Rumana CS, Gopinath SP, Uzura M, Valadka AB, Robertson CS (1998) Brain temperatures exceeds systemic temperatures in head-injured patients. Clin Care Med 26:562-567
92. Ryan KL, Taylor WF, Bishop VS (1997) Arterial baroreflex modulation of heat-induced vasodilation in the rabbit ear. J Appl Physiol 83:2091-2097
93. Sandoval V, Hanson GR, Fleckenstein AE (2000) Methamphetamine decreases mouse striatal dopamine transporter activity: Roles of hyperthermia and dopamine. Eur J Pharmacol 409:265-271
94. Satinoff E (1978) Neural organization and evolution of thermal regulation in mammals. Schence 201:16-22
95. Schaefer CF (1979) Possible teratogenic hyperthermia and marathon running. JAMA 241:1892
96. Schmidt-Nielsen K (1997) Animal physiology. Adaptation and environment, 5th edn, Cambridge University Press, Cambridge
97. Serota HM (1939) Temperature changes in the cortex and hypothalamus during sleep. J Neurophysiol 2:42-47
98. Serota HM, Gerard RW (1938) Localized thermal changes in cat's brain. J Neurophysiol 1:115-124
99. Sessler D (2000) Perioperative heat balance. Anesthesiology 92:578-596
100. Siesjo B (1978) Brain energy metabolism. Wiley, New York
101. Sharma HS (2006) Hyperthermia-induced brain aedema: Current status and future perspectives. Indian J Med Res 123:629-652
102. Sharma HS, Ali SF (2006) Alterations in blood-brain barrier function by morphine and methamphetamine. Ann NY Acad Sci 1074:198-224
103. Sharma HS, Hoopes PJ (2003) Hyperthermia-induced pathophysiology of the central nervous system. Int J Hyperthermia 19:325-354
104. Sharma HS, Alm P, Westman J (1998) Nitric oxide and carbon monoxide in the pathophysiology of brain functions in heat stress. Prog Brain Res 115:297-333
105. Shulman RG, Rothman DL, Behar KL, Hyder F (2004) Energetic basis of brain activity: Implications for neuroimaging. Trends Neurosci 27:489-495
106. Sokoloff L (1999) Energetics of functional activation in neural tissues. Neurochem Res 24:321-329
107. Suehiro E, Fujisawa H, Ito H, Ishikawa T, Maekawa T (1999) Brain temperature modifies glutamate neurotoxicity in vivo. J Neurotrauma 16:285-297
108. Sukstanskii AL, Yablonskiy DA (2006) Theoretical model of temperature regulation in the brain during changes in functional activity. Proc Natl Acad Sci 103:12144-12149
109. Swan H (1974) Thermoregulation and bioenergetics. Elsevier, New York
110. Thompson SM, Musakawa LM, Rince DA (1985) Temperature dependence of intrinsic membrane properties and synaptic potentials in hippocampal CA1 neurons in vitro. J Neurosci 5:817-824
111. Travis KA, Bockholt HJ, Zardetto-Smith AM, Johnson AK (1995) In vitro thermorensitivity of the midline thalamus. Brain Res 686:17-22
112. Trubel HKF, Sacolick LI, Hyder F (2006) Regional temperature changes in the brain during somatosensory stimulation, J Cereb Blood Flow Metab 26:68-78
113. Tryba AK, Ramirez J-M (2004) Hyperthermia modulates respiratory pacemaker bursting properties. J Neurophysiol 92:2844-2852
114. Uda M, Tanaka Y (1990) Arterial blood flow changes after hyperthermia on normal liver, normal brain, and normal small intestine. Gan No Rinsho 36:2362-2366
115. Vizi ES (1998) Different temperature dependence of carrier-mediated (cytoplasmic) and stimulus-evoked (exocytotic) release of transmitter: A simple method to separate the two types of release. Neurochem Int 33:359-356
116. Volgushev M, Vidyasagar TR, Chistiakova M, Eysel UT (2000) Synaptic transmission in the neocortex during reversible cooling. Neuroscience 98:9-22
117. Wass C, Cable D, Schaff H, Lanier W (1998) Anesthetic technique influences brain temperature during cardiopulmonary bypass in dogs. Ann Thorac Surg 65:454-460
118. Willis WT, Jackman MR, Bizeau ME, Pagliassotti MJ, Hazel JR (2000) Hyperthermia impairs liver mitochondrial functions. Am J Physiol 278:R1240-R1246
119. Xie T, McGann UD, Kim S, Yuan J, Ricaurte GA (2000) Effect of temperature on dopamine transporter function and intracellular accumulation of methamphetamine: Implications for methamphetamine-induced dopaminergic neurotoxicity. J Neurosci 20:7838-7845
120. Yablonskiy DA, Ackerman JH, Raichle ME (2000) Coupling between changes in human brain temperature and oxidative metabolism during prolonged visual stimulation. Proc Natl Acad Aci 97:7603-7608
121. Zhu M, Nehra D, Ackerman J, Yablonskiy DA (2004) On the role of anesthesia on the body/brain temperature differential in rats. J Thermal Biol 29:599-603