echinus, required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases

BMC Developmental Biology

Volumn 7, Issue , 2007, Pages

  Copeland, Jeffrey M ^a   Bosdet, Ian ^b   Freeman, J Douglas ^b   Guo, Ming ^c   Gorski, Sharon M ^b   Hay, Bruce A ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALSENILIN; CASPASE; ECHINUS PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HEAD INVOLUTION DEFECTIVE PROTEIN; NOTCH RECEPTOR; PROTEIN; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; CYSTEINE PROTEINASE; DROSOPHILA PROTEIN; ECHINUS PROTEIN, DROSOPHILA; ISOPROTEIN; PROTEINASE; UBIQUITIN; UBIQUITIN SPECIFIC PROTEASE; UBIQUITIN-SPECIFIC PROTEASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL SELECTION; DROSOPHILA; GENE FREQUENCY; INSECT; NONHUMAN; RETINA; ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; APOPTOSIS; CELL LINEAGE; CHEMISTRY; CYTOLOGY; DNA SEQUENCE; DROSOPHILA MELANOGASTER; EYE; FEMALE; GENE EXPRESSION; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MOLECULAR GENETICS; MUTATION; NICK END LABELING; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SCANNING ELECTRON MICROSCOPY; SEQUENCE HOMOLOGY; ULTRASTRUCTURE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CELL LINEAGE; CYSTEINE ENDOPEPTIDASES; DNA, COMPLEMENTARY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDOPEPTIDASES; EYE; FEMALE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN ISOFORMS; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN;

EID: 34548154740     PISSN: None     EISSN: 1471213X     Source Type: Journal    
DOI: 10.1186/1471-213X-7-82     Document Type: Article

References (86)

1. The emergence of order in the Drosophila pupal retina. RL Cagan DF Ready, Dev Biol 1989 136 2 346 362 10.1016/0012-1606(89)90261-3 2511048
2. Cell death in normal and rough eye mutants of Drosophila. T Wolff DF Ready, Develop 1991 113 825 839
3. Caspase-dependent cell death in Drosophila. BA Hay M Guo, Annu Rev Cell Dev Biol 2006 22 623 650 10.1146/annurev.cellbio.21.012804.093845 16842034
4. Caspase activation, inhibition, and reactivation. Y Shi, Protein Science 2004 13 1979 1987 10.1110/ps.04789804 15273300
5. The Drosophila caspase DRONC is regulated by DIAP1. P Meier J Silke SJ Leevers GI Evan, Embo J 2000 19 4 598 611 10675329 10.1093/emboj/19.4.598
6. The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM. CJ Hawkins SJ Yoo EP Peterson SL Wang SY Vernooy BA Hay, J Biol Chem 2000 275 35 27084 27093 10825159
7. The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila. SK Chew F Akdemir P Chen WJ Lu K Mills T Daish S Kumar A Rodriguez JM Abrams, Developmental Cell 2004 7 897 907 10.1016/j.devcel.2004.09. 016 15572131
8. Drosophila caspase Dronc is required for specific developmental cell death pathways and stress-induced apoptosis. TJ Daish K Mills S Kumar, Developmental Cell 2004 7 909 915 10.1016/j.devcel.2004.09.018 15572132
9. The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila. D Xu Y Li M Arcaro M Lackey A Bergmann, Development 2005 132 2125 2134 10.1242/dev.01790 15800001
10. A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye. SY Yu SJ Yoo L Yang C Zapata A Srinivasan BA Hay, Development 2002 129 3269 3278 12070100
11. The effector caspases drICE and dcp-1 have partially overlapping functions in the apoptotic pathway in Drosophila. D Xu Y Wang R Willecke Z Chen T Ding A Bergmann, Cell Death Differ 2006 13 1697 1706 10.1038/sj.cdd.4401920 16645642
12. The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process. I Muro DL Berry JR Huh CH Chen H Huang JH Seoul SJ Yoo M Guo EH Baehrecke BA Hay, Development 2006 133 3305 3315 10.1242/dev.02495 16887831
13. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. SL Wang CJ Hawkins SJ Yoo HA Muller BA Hay, Cell 1999 98 4 453 463 10.1016/S0092-8674(00)81974-1 10481910
14. A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1. CJ Hawkins SL Wang BA Hay, Proc Natl Acad Sci U S A 1999 96 6 2885 2890 10077606 10.1073/pnas.96.6.2885
15. The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. R Wilson L Goyal M Ditzel A Zachariou DA Baker J Agapite H Steller P Meier, Nature Cell Biology 2002 4 6 445 450 10.1038/ncb799 12021771
16. Molecular mechanisms of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination. J Chai N Yan JR Huh JW Wu W Li BA Hay Y Shi, Nature Structural Biology 2003 10 892 898 10.1038/nsb989 14517550
17. IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding. A Zachariou T Tenev L Goyal J Agapite H Steller P Meier, EMBO J 2003 22 6642 6652 14657035 10.1093/emboj/cdg617
18. Molecular mechanisms of Drice inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim. N Yan JW Wu J Chai W Li Y Shi, Nature Structural and Molecular Biology 2004 11 420 428 10.1038/nsmb764
19. IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms. T Tenev A Zachariou R Wilson M Ditzel P Meier, Nature Cell Biology 2005 7 70 77 10.1038/ncb1204 15580265
20. Genetic control of programmed cell death in Drosophila. K White ME Grether JM Abrams L Young K Farrell H Steller, Science 1994 264 5159 677 683 10.1126/science.8171319 8171319
21. The head involution defective gene of Drosophila melanogaster functions in programmed cell death. ME Grether JM Abrams J Agapite K White H Steller, Genes Dev 1995 9 14 1694 1708 10.1101/gad.9.14.1694 7622034
22. grim, a novel cell death gene in Drosophila. P Chen W Nordstrom B Gish JM Abrams, Genes Dev 1996 10 14 1773 1782 10.1101/gad.10.14.1773 8698237
23. The Damage-Responsive Drosophila Gene sickle Encodes a Novel IAP Binding Protein Similar to but Distinct from reaper, grim, and hid. A Christich S Kauppila P Chen N Sogame SI Ho JM Abrams, Curr Biol 2002 12 2 137 140 10.1016/S0960-9822(01)00658-3 11818065
24. sickle, a Novel Drosophila Death Gene in the reaper/hid/grim Region, Encodes an IAP-Inhibitory Protein. SM Srinivasula P Datta M Kobayashi JW Wu M Fujioka R Hegde Z Zhang R Mukattash T Fernandes-Alnemri Y Shi JB Jaynes ES Alnemri, Curr Biol 2002 12 2 125 130 10.1016/S0960-9822(01)00657-1 11818063
25. Drosophila sickle Is a Novel grim-reaper Cell Death Activator. JP Wing JS Karres JL Ogdahl L Zhou LM Schwartz JR Nambu, Curr Biol 2002 12 2 131 135 10.1016/S0960-9822(01)00664-9 11818064
26. Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1. T Tenev A Zachariou R Wilson A Paul P Meier, Embo J 2002 21 19 5118 5129 12356728 10.1093/emboj/cdf530
27. Ras promotes cell survival in Drosophila by downregulating hid expression. P Kurada K White, Cell 1998 95 3 319 329 10.1016/S0092-8674(00) 81764-X 9814703
28. Apoptosis inducers Hid, Rpr and Grim negatively regulate levels of the caspase inhibitor DIAP1 by distinct mechanisms. SJ Yoo JR Huh I Muro H Yu L Wang SL Wang RMR Feldman RJ Clem HAJ Muller BA Hay, Nature Cell Biol 2002 4 416 424 10.1038/ncb793 12021767
29. Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1. R Hays L Wickline R Cagan, Nature Cell Biology 2002 4 6 425 431 10.1038/ncb794 12021768
30. Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition. CL Holley MR Olson DA Colon-Ramos S Kornbluth, Nature Cell Biol 2002 4 439 444 10.1038/ncb798 12021770
31. Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1. [erratum appears in Nat Cell Biol 2002 Jul;4(7):546.]. HD Ryoo A Bergmann H Gonen A Ciechanover H Steller, Nature Cell Biology 2002 4 6 432 438 10.1038/ncb795 12021769
32. Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis. JP Wing BA Schreader T Yokokura Y Wang PS Andrews N Huseinovic CK Dong JL Ogdahl LM Schwartz K White JR Nambu, Nat Cell Biol 2002 4 6 451 456 10.1038/ncb800 12021772
33. Reaper is regulated by IAP-mediated ubiquitination. MR Olson CL Holley SJ Yoo JR Huh BA Hay S Kornbluth, J Biol Chem 2002 278 4028 4034 10.1074/jbc.M209734200 12446669
34. Grim stimulates DIAP1 poly-ubiquitination by binding to UbcD1. SJ Yoo, Mol Cells 2005 20 446 451 16404163
35. The irregular chiasm C-roughest locus of Drosophila, which affects axonal projections and programmed cell death, encodes a novel immunoglobulin-like protein. RGP Ramos GL Igloi B Lichte U Baumann D Maier T Schneider JH Brandstatter A Frohlich KF Fischbach, Genes Dev 1993 7 2533 2547 10.1101/gad.7.12b.2533 7503814
36. Delta and Notch promote correct localization of IrreC-rst. SM Gorski C Baker Brachmann SB Tanenbaum RL Cagan, Cell Death and Differentiation 2000 7 1011 1013 10.1038/sj.cdd.4400742
37. Preferential adhesion mediated by Hibris and Roughest regulates morphogenesis and patterning in the Drosophila eye. S Bao R Cagan, Developmental Cell 2005 8 925 935 10.1016/j.devcel.2005.03.011 15935781
38. IrreC/rst-mediated cell sorting during Drosophila pupal eye development depends on proper localization of DE-cadherin. NA Grzeschik E Knust, Development 2005 132 2035 2045 10.1242/dev.01800 15788453
39. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. M Freeman, Cell 1996 87 651 660 10.1016/S0092-8674(00)81385-9 8929534
40. Local induction of patterning and programmed cell death in the developing Drosophila retina. DT Miller RL Cagan, Development 1998 125 2327 2335 9584131
41. The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling. A Bergmann J Agapite K McCall H Steller, Cell 1998 95 3 331 341 10.1016/S0092-8674(00)81765-1 9814704
42. Distinct monoubiquitin signals in receptor endocytosis. I Dikic, Trends in Biochemical Sciences 2003 28 598 604 10.1016/j.tibs.2003.09.005 14607090
43. The roles of receptor and ligand endocytosis in regulating Notch signaling. R Le Borgne A Bardin F Schweisguth, Development 2005 132 1751 1762 10.1242/dev.01789 15790962
44. Lozenge directly activates argos and klumpfuss to regulate programmed cell death. J Wildonger A Sosinsky B Honig RS Mann, Genes and Development 2005 19 1034 1039 10.1101/gad.1298105
45. Mutations in lozenge and D-Pax2 invoke ectopic patterned cell death in the developing Drosophila eye using distinct mechanisms. NA Siddall KJ Behan J Crew R. TL Cheung JA Fair P Batterham JA Pollock, Dev Genes Evol 2003 213 107 119 12690448
46. Lozenge is expressed in pluripotent precursor cells and patterns multiple cell types in the Drosophila eye through the control of cell-specific transcription factors. GV Flores A Daga HR Kalhor U Banerjee, Development 1998 125 3681 3687 9716533
47. klumpfuss regulates cell death in the Drosophila retina. JC Rusconi JL Fink R Cagan, Mechanisms of Development 2004 121 537 546 10.1016/j.mod.2004.04. 008 15172685
48. The genome of Drosophila melanogaster. DL Lindsley GG Zimm, San Diego, Academic Press 1992
49. Reorganization of membrane contacts prior to apoptosis in the Drosophila retina: the role of the IrreC-rst protein. C Reiter T Schimansky Z Nie KF Fischbach, Development 1996 122 6 1931 1940 8674431
50. Expression of baculovirus P35 prevents cell death in Drosophila. BA Hay T Wolff GM Rubin, Development 1994 120 8 2121 2129 7925015
51. Patterning the fly eye: the role of apoptosis. C Baker Brachmann RL Cagan, Trends in Genetics 2003 19 91 96 10.1016/S0168-9525(02)00041-0 12547518
52. FlyBase. http://flybase.bio.indiana.edu/reports/FBgn0000542.html
53. An analysis of transvection at the yellow locus of Drosophila melanogaster. JR Morris J Chen ST Filandrinos RC Dunn R Fisk PK Geyer C Wu, Genetics 1999 151 633 651 9927457
54. Biological function of unannotated transcription during the early development of Drosophila melanogaster. JR Manak S Dike V Sementchenko P Kapranov F Biemar J Long J Cheng I Bell S Ghosh A Piccolboni TR Gingeras, Nature Genetics 2006 38 1151 1158 10.1038/ng1875 16951679
55. Rhodopsin formation in Drosophila is dependent on the PINTA retinoid-binding protein. T Wang C Montell, J Neurosci 2005 25 5187 5194 10.1523/JNEUROSCI.0995-05.2005 15917458
56. The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells. K Moses MC Ellis GM Rubin, Nature 1989 340 531 536 10.1038/340531a0 2770860
57. Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein. MC Ellis EM O'Neill GM Rubin, Development 1993 119 3 855 865 8187644
58. Mechanism and function of deubiquitinating enzymes. AY Amerik M Hochstrasser, Biochemica et Biophysica Acta 2004 1695 189 207
59. A genomic and functional inventory of deubiquitinating enzymes. SMB Nijman MPA Luna-Vargas A Velds TR Brummelkamp AMG Dirac TK Sixma R Bernards, Cell 2005 123 773 786 10.1016/j.cell.2005.11.007 16325574
60. >Crystal Structure of a UBP-Family Deubiquitinating Enzyme in Isolation and in Complex with Ubiquitin Aldehyde. M Hu P Li M Li W Li T Yao J-W Wu W Gu RE Cohen Y Shi, Cell 2002 111 1041 1054 10.1016/S0092-8674(02)01199-6 12507430
61. Stucture and mechanisms of the proteosome-associated deubiquitinating enzyme USP14. M Hu P Li L Song PD Jeffrey TA Chernova WD Wilkinson RE Cohen Y Shi, EMBO J 2005 24 3747 3756 16211010 10.1038/sj.emboj.7600832
62. Ubiquitin-specific proteases of Saccharomyces cerevisiae: Cloning of UBP2 and UBP3, and functional analysis of the UBP family. RT Baker JW Tobias A Varshavsky, J Biol Chem 1992 267 23364 23375 1429680
63. Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene. Y Huang RT Baker JA Fischer-Vise, Science 1995 270 1828 1831 10.1126/science.270.5243.1828 8525378
64. Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. V Quesada A Diaz-Perales A Gutierrez-Fernandez C Garabaya S Cal C Lopez-Otin, BBRC 2004 314 54 62 14715245
65. Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae. AY Amerik SJ Li M Hochstrasser, Biol Chem 2000 381 981 992 10.1515/BC.2000.121 11076031
66. UBP43 (USP18) specifically removes ISG15 from conjugated proteins. MP Malakhov OA Malakhova KI Kim KJ Ritchie DE Zhang, J Biol Chem 2002 277 9976 9981 10.1074/jbc.M109078200 11788588
67. Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins. L Gong T Kamitani S Millas ET Yeh, J Biol Chem 2000 275 14212 14216 10.1074/jbc.275.19.14212 10799498
68. UBPY: A growth-regulated human ubiquitin isopeptidase. S Naviglio C Mattecucci B Matoskova T Nagase N Nomura PP Di Fiore GF Draetta, EMBO J 1998 17 3241 3250 9628861 10.1093/emboj/17.12.3241
69. Regulation of the G1 to S transition by the ubiquitin pathway. LM DeSalle M Pagano, FEBS Lett 2001 490 179 189 10.1016/S0014-5793(01)02121-4 11223033
70. Protease degradomics: a new challenge for proteomics. C Lopez-Otin CM Overall, Nat Rev Mol Cell Biol 2002 3 509 519 10.1038/nrm858 12094217
71. Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. M Li D Chen A Shiloh J Luo AY Nikolaev J Qin W Gu, Nature 2002 416 648 653 10.1038/nature737 11923872
72. UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. OA Malakhova KI Kim JK Luo W Zou KGS Kumar SY Fuchs K Shuai DE Zhang, EMBO J 2006 25 2358 2367 16710296 10.1038/sj.emboj.7601149
73. RNAi Triggered by Symmetrically Transcribed Transgenes in Drosophila melanogaster. E Giordano R Rendina I Peluso M Furia, Genetics 2002 160 2 637 648 11861567
74. Klumpfuss, a Drosophila gene encoding a member of the EGR family of transcription factors, is involved in bristle and leg development. T Klein JA Campos-Ortega, Development 1997 124 3123 3134 9272953
75. The Drosophila microRNA mir-14 suppresses cell death and is required for normal fat metabolism. P Xu SY Vernooy M Guo BA Hay, Current Biology 2003 13 790 795 10.1016/S0960-9822(03)00250-1 12725740
76. The Drosophila Inhibitor of Apoptosis DIAP2 is required for the innate immune response to Gram-negative bacterial infection, and can be negatively regulated by IAP-binding proteins of the Reaper/Hid/Grim family. JR Huh I Foe CH Chen M Guo JM Park BA Hay, J Biol Chem 2006 282 2056 2068 10.1074/jbc. M608051200 17068333
77. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death. BA Hay DA Wassarman GM Rubin, Cell 1995 83 7 1253 1262 10.1016/0092-8674(95)90150-7 8548811
78. Drosophila Bruce can potently suppress Rpr- and Grim-dependent but not Hid-dependent cell death. SY Vernooy V Chow J Su K Verbrugghe J Yang S Cole MR Olson BA Hay, Curr Biol 2002 12 1164 1168 10.1016/S0960-9822(02)00935-1 12121627
79. TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development. Y Takatsu M Nakamura M Stapleton MC Danos K Matsumoto MB O'Connor H Shibuya N Ueno, Mol Cell Biol 2000 20 3015 3026 10757786 10.1128/MCB.20.9.3015- 3026.2000
80. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. D Tautz C Pfeifle, Chromosoma 1989 98 2 81 85 10.1007/BF00291041 2476281
81. Effect on eye development of dominant mutations in Drosophila homologue of the EGF receptor. NE Baker GM Rubin, Nature 1989 340 150 153 10.1038/340150a0 2500601
82. Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila. AM Lesokhin SY Yu J Katz NE Baker, Dev Biol 1999 205 129 144 10.1006/dbio.1998.9121 9882502
83. Regulation of EGF receptor signaling establishes pattern across the developing Drosophila retina. SA Spencer PA Powell DT Miller RL Cagan, Development 1998 125 4777 4790 9806926
84. Notch activity in neural cells triggered by a mutant allele with altered glycosylation. Y Li L Li KD Irvine NE Baker, Development 2003 130 2829 2840 10.1242/dev.00498 12756168
85. Temperature-sensitive mutations of the Notch locus in Drosophila melanogaster. DL Shellenbarger JD Mohler, Genetics 1975 81 143 162 812766
86. Notch is required for successive cell decisions in the developing Drosophila retina. RL Cagan DF Ready, Genes & Dev 1989 3 1099 1112 10.1101/gad.3.8.1099 2792755