The novel antiepileptic agent RWJ-333369-A, but not its analog RWJ-333369, reduces regional cerebral edema without affecting neurobehavioral outcome or cell death following experimental traumatic brain injury

Restorative Neurology and Neuroscience

Volumn 25, Issue 2, 2007, Pages 77-90

  Keck, Carrie A ^a   Thompson, Hilaire J ^a,b,g   Pitkänen, Asla ^c,d   LeBold, David G ^a   Morales, Diego M ^a,e   Plevy, Jamie B ^a   Puri, Rishi ^a   Zhao, Boyu ^f   Dichter, Marc ^a   McIntosh, Tracy K ^a,e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d KUOPIO UNIVERSITY HOSPITAL   (Finland)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^g Box 357266 ^*  (United States)

Author keywords

Antiepileptic drugs (AEDs); Brain swelling; Head injury; Neuroprotection; Post traumatic epilepsy

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMIC ACID 2 (2 CHLOROPHENYL) 2 HYDROXYETHYL ESTER; RWJ 333369 A; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN EDEMA; CELL DEATH; COGNITION; CONTROLLED STUDY; DRUG EFFICACY; HEMISPHERE; HIPPOCAMPUS; LEARNING; MALE; MOTOR PERFORMANCE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RANDOMIZATION; RAT; TRAUMATIC BRAIN INJURY;

ANIMALS; ANTICONVULSANTS; BEHAVIOR, ANIMAL; BRAIN EDEMA; BRAIN INJURIES; CARBAMATES; CELL DEATH; COGNITION; MALE; MAZE LEARNING; MOTOR ACTIVITY; NERVOUS SYSTEM; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; SWIMMING;

EID: 34548092162     PISSN: 09226028     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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