Tissue tears in the white matter after lateral fluid percussion brain injury in the rat: Relevance to human brain injury

Acta Neuropathologica

Volumn 99, Issue 2, 2000, Pages 117-124

  Graham, D I ^a   Raghupathi, R ^b   Saatman, K E ^b   Meaney, D ^c   McIntosh, T K ^b  

^a NHS GREATER GLASGOW AND CLYDE   (United Kingdom)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Lateral fluid percussion; Rat; Tissue tears; Traumatic brain injury

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; SCAR FORMATION; WHITE MATTER;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ASTROCYTES; AXONS; BRAIN; BRAIN INJURIES; CEREBRAL CORTEX; CICATRIX; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; HUMANS; MALE; NECROSIS; NERVE FIBERS, MYELINATED; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0033973418     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00007414     Document Type: Article

References (57)

1. Adams JH, Mitchell DE, Graham DI, Doyle D (1977) Diffuse brain damage of immediate impact type. Brain 100: 489-502
2. Adams JH, Graham DI, Murray LS, Scott G (1982) Diffuse axonal injury due to non-missile head injury in humans: an analysis of 45 cases. Ann Neurol 12: 557-563
3. Adams JH, Doyle D, Ford I, Gennarelli TA, Graham DI, McClellan DR (1989) Diffuse axonal injury in head injury: definition, diagnosis, and grading. Histopathology 15: 49-59
4. Blumhergs PC, Jones NR, North JB (1989) Diffuse axonal injury in head trauma. J Neurol Neurosurg Psychiatry 52: 838-841
5. Blumbergs PC, Oatey PE, Sandhu A, Thomas AC, Simpson DA (1994) Pontomedullary tear in a speedboat accident. Report of a case with MRI diagnosis. Zentralbl Neurochir 52: 89-93
6. Blumbergs PC, Scott G, Manavis J, Wainwright H, Simpson DA, McLean AJ (1994) Staining of amyloid precursor protein to study axonal damage in mild head injury. Lancet 344: 1055-1056
7. Blumbergs PC, Scott G, Manavis J, Wainwright H, Simpson DA, McLean AJ (1995) Topography of axonal injury as defined by amyloid precursor protein and the sector scoring method in mild and severe closed head injury. J Neurotrauma 12: 565-572
8. Bramlett HM, Dietrich WD, Green EJ, Busto, R (1997) Chronic histopathological consequences of fluid-percussion brain injury in rats: effects of post-traumatic hypothermia. Acta Neuropathol 93: 190-199
9. Cortez SC, McIntosh TK, Noble LJ (1989) Experimental fluid percussion brain injury: vascular disruption and neuronal and glial alterations. Brain Res 482: 271-282
10. Gean AD (1994) White matter shearing injury and brainstem injury. In: Imaging of head trauma. Raven Press, New York, pp 207-248
11. Gennarelli TA (1993) Cerebral concussion and diffuse brain injuries. In: Cooper PR (ed) Head injury, 3rd edn. Williams & Wilkins, Baltimore, pp 137-158
12. Gennarelli TA (1994) Animate models of human head injury. J Neurotrauma 11: 357-368
13. Gennurelli TA (1996) The spectrum of traumatic axonal injury. Neuropathol Appl Neurobiol 22: 509-513
14. Gennarelli TA, Thibault LE, Adams JH, Graham DI, Thompson CJ, Marcincin RP (1982) Diffuse axonal injury and traumatic coma in the primate. Ann Neurol 12: 564-574
15. Gennarelli TA, Thibault LE, Tomei G, Wiser R, Graham DI, Adams JH (1987) Directional dependence of axonal brain injury due to centroidal and non-centroidal acceleration. Proceedings of 31st Stapp Car Crash Conference Society of Automotive Engineers, pp 48-53
16. Gennarelli TA, Thibault LE, Graham DI (1998) Diffuse axonal injury: an important form of traumatic brain damage. Neuroscientist 4: 202-215
17. Gentleman S, Nash M, Sweeting CJ, Graham DI, Roberts GW (1993) β-Amyloid precursor protein (β-APP) as a marker for axonal injury after head injury. Neurosci Lett 160: 139-144
18. Gentry LR, Godersky JC, Thompson B (1988) MR imaging of head trauma: review of the distribution and radiopathologic features of traumatic lesions. Am J Neuroradiol 9: 101-110
19. Gentry LR, Godersky JC, Thompson B (1988) MR imaging of head trauma: review of the distribution and radiopathologic features of traumatic lesions. Am J Radiol 150: 664-672
20. Gentry LR, Thompson B, Godersky JC (1988) Trauma to the corpus callosum: MR features. Am J Neuroradiol 9: 1129-1138
21. Graham DI, Gennarelli TA (1997) Trauma. In: Graham DI, Lantos PL (eds) Greenfield's neuropathology, 6th edn. Arnold, London, pp 197-262
22. Grcevic N (1982) Topography and pathogenic mechanisms of lesions in "inner cerebral trauma". Rad Jun Akad Znsn Umj Od Med Nauke 402/18: 265-331
23. Hicks RR, Smith DH, Lowenstein DH, Saint Marie R, McIntosh TK (1993) Mild experimental brain injury in the rat induces cognitive deficits associated with regional neuronal loss in the hippocampus. J Neurotrauma 19: 405-414
24. Hicks R, Soares H, Smith D, McIntosh T (1996) Temporal and spatial characterization of neuronal injury following lateral fluid percussion brain injury in the cat. Acta Neuropathol 91: 236-246
25. Kalaria RN, Bhatti S, Palatinsky EA, Pennington DH. Shelton ER, Chan HW, Perry G, Lust DW (1993) Accumulation of the β-amyloid precursor protein at sites of ischemic injury in rat brain. Neuroreport 4: 211-214
26. Lewen A, Li GL, Nilsson P, Olsson Y, Hillered L (1995) Traumatic brain injury in rat produces changes of β-amyloid precursor protein immunoreaction. Neuroreport 6: 357-360
27. Lowenstein D, Thomas M, Smith D, McIntosh T (1992) Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus. J Neurosci 12: 4804-4853
28. Maxwell WL, Watt C, Graham DI, Gennarelli TA (1993) Ultrastructural evidence of axonal shearing as a result of lateral acceleration of the head in non-human primate. Acta Neuropathol 86: 136-144
29. Maxwell WL, Povlishock JT, Graham DI (1997) A mechanistic analysis of nondisruptive axonal injury: a review. J Neurotrauma 14: 419-440
30. McIntosh TK, Vink R, Noble L, Yamakami I, Fernyak S, Faden AI (1989) Traumatic brain injury in the rat: characterisation of a lateral fluid percussion model. Neuroscience 23: 233-244
31. Meaney DF, Smith DH, Shreiber DI, Bain AC, Miller RT, Ross DT, Gennarelli TA (1995) Biomechanical analysis of experimental diffuse axonal injury. J Neurotrauma 12: 689-694
32. Osborne KA, Shigeno T, Balarsky AM, Ford I, McCulloch J, Teasdale GM, Graham DI (1987) Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia. J Neurol Neurosurg Psychiatry 50: 402-410
33. Peerless SJ, Rewcastle NB (1967) Shear injuries of the brain. Can Med Assoc J 96: 577-582
34. Pierce JES, Trojanowski TQ, Graham DI, Smith DH, McIntosh TK (1996) Immunohistochemical characterisation of alterations in the distribution of amyloid precursor proteins and amyloid β-peptide following experimental brain injury in the rat. J Neurosci 16: 1083-1090
35. Pierce JES, Smith DH, Trojanowski JQ, McIntosh TK (1998) Enduring cognitive, neurobehavioral, and histopathological changes persist for up to one year following severe experimental brain injury in rats. Neuroscience 87: 359-369
36. Pileri SA, Roncador G, Ceccarelli C, Piccioli M, Briskomatis A. Sabattini E. Ascani S, Santini D, Piccaluga PP, Leone O, Damiani S, Ercolessi C, Sandri F, Pieri F, Leoncini L, Falini B (1997) Antigen retrieval techniques in immunohistochemistry: comparison of different methods. J Pathol 183: 116-123
37. Pilz P (1983) Axonal injury in head injury. Acta Neurochirurg 32 [Suppl]: 119-123
38. Pilz P, Strohecker J, Grobovschek M (1982) Survival after pontomedullary tear. J Neurol Neurosurg Psychiatry 45: 422-427
39. Povlishock JT, Christman CW (1995) The pathobiology of traumatically induced axonal injury in animals and humans: a review of current thoughts. J Neurotrauma 12: 555-564
40. Povlishock JT, Jenkins LW (1995) Are the pathobiological changes evoked by traumatic brain injury immediate and irreversible? Brain Pathol 5: 415-426
41. Povlishock JT, Erb DE, Astruc J (1992) Axonal response to traumatic brain injury: reactive axonal change, deafferentation and neuroplasticity. J Neurotrauma 9: 189-200
42. Saatman KE, Bozyczko-Coyne D, Marcy VR, Siman R, McIntosh TK (1996) Prolonged calpain-mediated spectrin breakdown occurs regionally following experimental brain injury in the rat. J Neuropathol Exp Neurol 55: 850-860
43. Saatman KE, Graham DI, McIntosh TK (1998) The neuronal cytoskeleton is at risk after mild and moderate brain injury. J Neurotrauma 15: 1047-1058
44. Schmidt RH, Grady MS (1993) Regional patterns of bloodbrain barrier breakdown following central and lateral fluid percussion injury in rodents. J Neurotrauma 10: 415-430
45. Sherriff FE, Bridges LR, Sivaloganathan S (1994) Early detection of axonal injury after head trauma using immunocytochemistry for β-amyloid precursor protein. Acta Neuropathol 87: 55-62
46. Simpson DA, Blumbergs PC, Cooler RD, Kilminster M, McLean AJ, Scott G (1989) Pontomedullary tears and other gross brainstem injuries after vehicular accidents. J Trauma 27: 1519-1525
47. Smith DH, Chen X-H, Pierce JES, Wolf JA, Trojanowski JQ, Graham DI, McIntosh TK (1997) Progressive atrophy and neuronal death for one year following brain trauma in the rat. J Neurotrauma 14: 715-727
48. Soares HD, Thomas M, Cloherty K, McIntosh TK (1992) Development of prolonged focal cerebral edema and regional cation changes following experimental brain injury in the rat. J Neurochem 58: 1845-1852
49. Soares HD, Hicks RR, Smith D, McIntosh TK (1995) Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury. J Neurosci 15: 8223-8233
50. Strich SJ (1956) Diffuse degeneration of the cerebral white matter in severe dementia following head injury. J Neurol Neurosurg Psychiatry 19: 163-185
51. Strich SJ (1961) Shearing of nerve fibres as a cause of brain damage due to head injury. Lancet II: 443-448
52. Strich SJ (1970) Lesions in the cerebral hemisphere after blunt head injury. J Clin Pathol 23 [Suppl] 4: 166-171
53. Tanno H, Nockels RP, Pitts LH, Noble LJ (1992) Breakdown of the blood-brain barrier after fluid percussion injury in the rat. Part 1. Distribution and time course of protein extravasation. J Neurotrauma 9: 21-32
54. Toulmond S, Duval D, Serrano A, Scatton B, Benavides J (1993) Biochemical and histological alternations induced by fluid percussion brain injury in the rat. Brain Res 620: 24-31
55. Yam PS, Dewar D, McCulloch J (1998) Axonal injury caused by focal cerebral ischemia in rat. J Neurotrauma 15: 441-450
56. Zimmerman RA, Larissa T, Bilaniuk LT, Gennarelli TA (1978) Computed tomography of shearing injuries of the cerebral white matter. Radiology 127: 393-396
57. Zimmerman RA, Bilaniuk LT, Hackney DB, Goldberg HI, Grossman RI (1986) Head injury: early results of comparing CT and high-field MR. Am J Neuroradiol 7: 757-764