Mechanistic studies on the intramolecular one-electron transfer between the two flavins in the human endothelial NOS reductase domain

Archives of Biochemistry and Biophysics

Volumn 465, Issue 1, 2007, Pages 254-265

  Nishino, Yoshitaka ^a   Yamamoto, Keita ^a,c   Kimura, Shigenobu ^a,b   Kikuchi, Akihiro ^c   Shiro, Yoshitsugu ^a,c   Iyanagi, Takashi ^a,c  

^a UNIVERSITY OF HYOGO   (Japan)

^b IBARAKI UNIVERSITY   (Japan)

^c RIKEN SPring 8 Center   (Japan)

Author keywords

Calmodulin; FAD FMN family; Flavin enzyme; Flavin neutral semiquinone; Human eNOS reductase domain; Intramolecular one electron transfer; Phosphorylation

Indexed keywords

CALCIUM ION; CALMODULIN; CYTOCHROME C; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FERRICYANIDE; FLAVINE ADENINE NUCLEOTIDE; FLAVINE MONONUCLEOTIDE; MENADIONE; OXYGEN; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SEMIQUINONE;

ARTICLE; CATALYSIS; ELECTRON TRANSPORT; ENDOTHELIUM CELL; ENZYME ACTIVITY; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

COMPUTER SIMULATION; ELECTRON TRANSPORT; FLAVINS; MODELS, CHEMICAL; NITRIC OXIDE SYNTHASE TYPE III; OXIDATION-REDUCTION; OXIDOREDUCTASES; PROTEIN STRUCTURE, TERTIARY;

EID: 34548025392     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2007.05.021     Document Type: Article

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