Tumor necrosis factor-α modulates effects of aryl hydrocarbon receptor ligands on cell proliferation and expression of cytochrome P450 enzymes in rat liver "Stem-Like" cells

Toxicological Sciences

Volumn 99, Issue 1, 2007, Pages 79-89

  Umannová, Lenka ^a,b   Zatloukalová, Jiřina ^a   Machala, Miroslav ^b   Krčmář, Pavel ^b   Májková, Zuzana ^c,d   Hennig, Bernhard ^c,d   Kozubík, Alois ^a,e   Vondráček, Jan ^a,b  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^c UNIVERSITY OF KENTUCKY   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

^e MASARYK UNIVERSITY   (Czech Republic)

Author keywords

Aryl hydrocarbon receptor; Cell proliferation; Dioxin; Polychlorinated biphenyl; Tumor necrosis factor a; Xenobiotic metabolizing enzymes

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3,3',4,4',5 PENTACHLOROBIPHENYL; AROMATIC HYDROCARBON RECEPTOR; CYCLIN A; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGAND; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL DISRUPTION; CELL PROLIFERATION; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVATION; IN VITRO STUDY; LIVER CARCINOGENESIS; LIVER CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; STEM CELL;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CARCINOGENS; CELL PROLIFERATION; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG INTERACTIONS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIGANDS; LIVER; POLYCHLORINATED BIPHENYLS; RATS; RATS, INBRED F344; RECEPTORS, ARYL HYDROCARBON; STEM CELLS; TETRACHLORODIBENZODIOXIN; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 34547912858     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm149     Document Type: Article

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