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Volumn 32, Issue 9, 2007, Pages 1876-1887

The effects of the preferential 5-HT2A agonist psilocybin on prepulse inhibition of startle in healthy human volunteers depend on interstimulus interval

Author keywords

5 HT1A; 5 HT2A; PPI; Psilocybin; Serotonin; Startle

Indexed keywords

PLACEBO; PSILOCYBINE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR;

EID: 34547882413     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301324     Document Type: Article
Times cited : (133)

References (69)
  • 1
    • 0015362013 scopus 로고
    • Lysergic acid diethylamide and serotonin: Direct action on serotonin-containing neurons in rat brain
    • Aghajanian GK, Haigler HJ, Bloom FE (1972). Lysergic acid diethylamide and serotonin: direct action on serotonin-containing neurons in rat brain. Life Sci 11: 615-622.
    • (1972) Life Sci , vol.11 , pp. 615-622
    • Aghajanian, G.K.1    Haigler, H.J.2    Bloom, F.E.3
  • 2
    • 0034055690 scopus 로고    scopus 로고
    • Serotonin model of schizophrenia: Emerging role of glutamate mechanisms
    • Aghajanian GK, Marek GJ (2000). Serotonin model of schizophrenia: emerging role of glutamate mechanisms. Brain Res Rev 31: 302-312.
    • (2000) Brain Res Rev , vol.31 , pp. 302-312
    • Aghajanian, G.K.1    Marek, G.J.2
  • 3
    • 0025924342 scopus 로고
    • 5-Hydroxytryptamine2 and 5-hydroxytryptamine 1A receptors mediate opposing responses on membrane excitability in rat association cortex
    • Araneda R, Andrade R (1991). 5-Hydroxytryptamine2 and 5-hydroxytryptamine 1A receptors mediate opposing responses on membrane excitability in rat association cortex. Neuroscience 40: 399-412.
    • (1991) Neuroscience , vol.40 , pp. 399-412
    • Araneda, R.1    Andrade, R.2
  • 4
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: Normal subjects, patient groups, and pharmacological studies
    • Braff DL, Geyer MA, Swerdlow NR (2001). Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berlin) 156: 234-258.
    • (2001) Psychopharmacology (Berlin) , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 5
    • 0026581360 scopus 로고
    • Gating and habituation of the startle reflex in schizophrenic patients
    • Braff DL, Grillon C, Geyer MA (1992). Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry 49: 206-215.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 206-215
    • Braff, D.L.1    Grillon, C.2    Geyer, M.A.3
  • 7
    • 0027490265 scopus 로고
    • Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder
    • Cadenhead KS, Geyer MA, Braff DL (1993). Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder. Am J Psychiatry 150: 1862-1869.
    • (1993) Am J Psychiatry , vol.150 , pp. 1862-1869
    • Cadenhead, K.S.1    Geyer, M.A.2    Braff, D.L.3
  • 8
    • 0033961241 scopus 로고    scopus 로고
    • Sensory gating deficits assessed by the P50 event-related potential in subjects with schizotypal personality disorder
    • Cadenhead KS, Light GA, Geyer MA, Braff DL (2000). Sensory gating deficits assessed by the P50 event-related potential in subjects with schizotypal personality disorder. Am J Psychiatry 157: 55-59.
    • (2000) Am J Psychiatry , vol.157 , pp. 55-59
    • Cadenhead, K.S.1    Light, G.A.2    Geyer, M.A.3    Braff, D.L.4
  • 9
    • 0034917565 scopus 로고    scopus 로고
    • Non-monotonic dependency of PPI on temporal parameters: Differential alteration by ketamine and MK-801 as opposed to apomorphine and DOI
    • Canal NM, Gourevitch R, Sandner G (2001). Non-monotonic dependency of PPI on temporal parameters: differential alteration by ketamine and MK-801 as opposed to apomorphine and DOI. Psychopharmacology 156: 169-176.
    • (2001) Psychopharmacology , vol.156 , pp. 169-176
    • Canal, N.M.1    Gourevitch, R.2    Sandner, G.3
  • 10
    • 0017639946 scopus 로고
    • Psilocybin: Biphasic dose-response effects on the acoustic startle reflex in the rat
    • Davis M, Walters JK (1977). Psilocybin: biphasic dose-response effects on the acoustic startle reflex in the rat. Pharmacol Biochem Behav 6: 427-431.
    • (1977) Pharmacol Biochem Behav , vol.6 , pp. 427-431
    • Davis, M.1    Walters, J.K.2
  • 12
    • 0001758110 scopus 로고
    • Psychological aspects of altered states of consciousness of the LSD type: Measurements of their basic dimensions and prediction of individual differences
    • Pletscher A, Ladewig D eds, Parthenon Publishing: New York. pp
    • Dittrich A (1994). Psychological aspects of altered states of consciousness of the LSD type: measurements of their basic dimensions and prediction of individual differences. In: Pletscher A, Ladewig D (eds). 50 Years of LSD. Current Status and Perspectives of Hallucinogens. Parthenon Publishing: New York. pp 101-118.
    • (1994) 50 Years of LSD. Current Status and Perspectives of Hallucinogens , pp. 101-118
    • Dittrich, A.1
  • 13
    • 0031824265 scopus 로고    scopus 로고
    • The standardized psychometric assessment of altered states of consciousness (ASCs) in humans
    • Dittrich A (1998). The standardized psychometric assessment of altered states of consciousness (ASCs) in humans. Pharmacopsychiat 31: 80-84.
    • (1998) Pharmacopsychiat , vol.31 , pp. 80-84
    • Dittrich, A.1
  • 14
    • 0001288904 scopus 로고
    • International study on altered states of consciousness (ISASC). Summary of the results
    • Dittrich A, von Arx S, Staub S (1985). International study on altered states of consciousness (ISASC). Summary of the results. Germ J Psych 9: 319-339.
    • (1985) Germ J Psych , vol.9 , pp. 319-339
    • Dittrich, A.1    von Arx, S.2    Staub, S.3
  • 15
    • 0034073387 scopus 로고    scopus 로고
    • Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice
    • Dulawa SC, Scearce-Levie KA, Hen R, Geyer MA (2000). Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice. Psychopharmacology 149: 306-312.
    • (2000) Psychopharmacology , vol.149 , pp. 306-312
    • Dulawa, S.C.1    Scearce-Levie, K.A.2    Hen, R.3    Geyer, M.A.4
  • 17
    • 0031824264 scopus 로고    scopus 로고
    • Behavioral studies of hallucinogenic drugs in animals: Implications for schizophrenia research
    • Geyer MA (1998). Behavioral studies of hallucinogenic drugs in animals: implications for schizophrenia research. Pharmacopsychiatry 31: 73-79.
    • (1998) Pharmacopsychiatry , vol.31 , pp. 73-79
    • Geyer, M.A.1
  • 18
    • 0023600009 scopus 로고
    • Startle habituation and sensorimotor gating in schizophrenia and related animal models
    • Geyer MA, Braff DL (1987). Startle habituation and sensorimotor gating in schizophrenia and related animal models. Schizophr Bull 13: 643-668.
    • (1987) Schizophr Bull , vol.13 , pp. 643-668
    • Geyer, M.A.1    Braff, D.L.2
  • 19
    • 0034917841 scopus 로고    scopus 로고
    • Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: A decade in review
    • Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR (2001). Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berlin) 156: 117-154.
    • (2001) Psychopharmacology (Berlin) , vol.156 , pp. 117-154
    • Geyer, M.A.1    Krebs-Thomson, K.2    Braff, D.L.3    Swerdlow, N.R.4
  • 20
    • 0036929065 scopus 로고    scopus 로고
    • Mouse genetic models for prepulse inhibition: An early review
    • Geyer MA, McIlwain KL, Paylor R (2002). Mouse genetic models for prepulse inhibition: an early review. Mol Psychiatry 7: 1039-1053.
    • (2002) Mol Psychiatry , vol.7 , pp. 1039-1053
    • Geyer, M.A.1    McIlwain, K.L.2    Paylor, R.3
  • 21
    • 0025038706 scopus 로고
    • Startle response models of sensorimotor gating and habituation deficits in schizophrenia
    • Geyer MA, Swerdlow NR, Mansbach RS, Braff DL (1990). Startle response models of sensorimotor gating and habituation deficits in schizophrenia. Brain Res Bull 25: 485-498.
    • (1990) Brain Res Bull , vol.25 , pp. 485-498
    • Geyer, M.A.1    Swerdlow, N.R.2    Mansbach, R.S.3    Braff, D.L.4
  • 23
    • 0031773867 scopus 로고    scopus 로고
    • Effects of the hallucinogen psilocybin on habituation and prepulse inhibition of the startle reflex in humans
    • Gouzoulis-Mayfrank E, Heekeren K, Thelen B, Lindenblatt H, Kovar KA, Sass H et al (1998b). Effects of the hallucinogen psilocybin on habituation and prepulse inhibition of the startle reflex in humans. Behav Pharmacol 9: 561-566.
    • (1998) Behav Pharmacol , vol.9 , pp. 561-566
    • Gouzoulis-Mayfrank, E.1    Heekeren, K.2    Thelen, B.3    Lindenblatt, H.4    Kovar, K.A.5    Sass, H.6
  • 24
    • 0016504948 scopus 로고
    • The more or less startling effects of weak prestimuli
    • Graham FK (1975). The more or less startling effects of weak prestimuli. Psychophysiology 12: 238-248.
    • (1975) Psychophysiology , vol.12 , pp. 238-248
    • Graham, F.K.1
  • 25
    • 0016040187 scopus 로고
    • Lysergic acid diethylamide and serotonin: A comparison of effects on serotonergic neurons and neurons receiving a serotonergic input
    • Haigler HJ, Aghajanian GK (1974). Lysergic acid diethylamide and serotonin: a comparison of effects on serotonergic neurons and neurons receiving a serotonergic input. J Pharmac Exp Ther 188: 688-699.
    • (1974) J Pharmac Exp Ther , vol.188 , pp. 688-699
    • Haigler, H.J.1    Aghajanian, G.K.2
  • 26
    • 1642273671 scopus 로고    scopus 로고
    • Acute psychological and physiological effects of psilocybin in healthy humans: A double-blind, placebo-controlled dose-effect study
    • Hasler F, Grimberg U, Benz MA, Huber T, Vollenweider FX (2004). Acute psychological and physiological effects of psilocybin in healthy humans: a double-blind, placebo-controlled dose-effect study. Psychopharmacology 172: 145-156.
    • (2004) Psychopharmacology , vol.172 , pp. 145-156
    • Hasler, F.1    Grimberg, U.2    Benz, M.A.3    Huber, T.4    Vollenweider, F.X.5
  • 27
    • 0028838730 scopus 로고
    • Prepulse inhibition of acoustic startle, a measure of sensorimotor gating: Effects of antipsychotics and other agents in rats
    • Johansson C, Jackson DM, Zhang J, Svensson L (1995). Prepulse inhibition of acoustic startle, a measure of sensorimotor gating: effects of antipsychotics and other agents in rats. Pharmacol Biochem Behav 52: 649-654.
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 649-654
    • Johansson, C.1    Jackson, D.M.2    Zhang, J.3    Svensson, L.4
  • 29
    • 0036019541 scopus 로고    scopus 로고
    • Effects of typical and atypical antipsychotics on prepulse inhibition in schizophrenia: A critical evaluation of current evidence and directions for future research
    • Kumari V, Sharma T (2002). Effects of typical and atypical antipsychotics on prepulse inhibition in schizophrenia: a critical evaluation of current evidence and directions for future research. Psychopharmacology 162: 97-101.
    • (2002) Psychopharmacology , vol.162 , pp. 97-101
    • Kumari, V.1    Sharma, T.2
  • 30
    • 0034085394 scopus 로고    scopus 로고
    • Prepulse inhibition of the startle response in men with schizophrenia: Effects of age of onset of illness, symptoms, and medication
    • Kumari V, Soni W, Mathew VM, Sharma T (2000). Prepulse inhibition of the startle response in men with schizophrenia: effects of age of onset of illness, symptoms, and medication. Arch Gen Psychiatry 57: 609-614.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 609-614
    • Kumari, V.1    Soni, W.2    Mathew, V.M.3    Sharma, T.4
  • 31
    • 0037770351 scopus 로고    scopus 로고
    • Deficits in prepulse inhibition and habituation in never-medicated, first-episode Schizophrenia
    • Ludewig K, Geyer MA, Vollenweider FX (2003a). Deficits in prepulse inhibition and habituation in never-medicated, first-episode Schizophrenia. Biol Psychiatry 54: 121-128.
    • (2003) Biol Psychiatry , vol.54 , pp. 121-128
    • Ludewig, K.1    Geyer, M.A.2    Vollenweider, F.X.3
  • 32
    • 33748750215 scopus 로고    scopus 로고
    • Prepulse inhibition and habituation in first-episode schizophrenia
    • Ludewig K, Geyer MA, Vollenweider FX (2003b). Prepulse inhibition and habituation in first-episode schizophrenia. Biol Psychiatry 53: 118S.
    • (2003) Biol Psychiatry , vol.53
    • Ludewig, K.1    Geyer, M.A.2    Vollenweider, F.X.3
  • 33
    • 0030434487 scopus 로고    scopus 로고
    • LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex
    • Marek GJ, Aghajanian GK (1996). LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex. J Pharmac Exp Ther 278: 1373-1382.
    • (1996) J Pharmac Exp Ther , vol.278 , pp. 1373-1382
    • Marek, G.J.1    Aghajanian, G.K.2
  • 34
    • 0035894871 scopus 로고    scopus 로고
    • Control of serotonergic function in medial prefrontal cortex by serotonin-2A receptors through a glutamate-dependent mechanism
    • Martin-Ruiz R, Puig MV, Celada P, Shapiro DA, Roth BL, Mengod G et al (2001). Control of serotonergic function in medial prefrontal cortex by serotonin-2A receptors through a glutamate-dependent mechanism. J Neurosci 21: 9856-9866.
    • (2001) J Neurosci , vol.21 , pp. 9856-9866
    • Martin-Ruiz, R.1    Puig, M.V.2    Celada, P.3    Shapiro, D.A.4    Roth, B.L.5    Mengod, G.6
  • 35
    • 0013578406 scopus 로고
    • Disorders of attention and perception in early schizophrenia
    • McGhie A, Chapman J (1961). Disorders of attention and perception in early schizophrenia. Br J Med Psychol 34: 103-116.
    • (1961) Br J Med Psychol , vol.34 , pp. 103-116
    • McGhie, A.1    Chapman, J.2
  • 36
    • 0025255521 scopus 로고
    • Differential interactions of indolealkylamines with 5-hydroxytrypamine receptor subtypes
    • McKenna DJ, Repke DB, Peroutka SJ (1990). Differential interactions of indolealkylamines with 5-hydroxytrypamine receptor subtypes. Neuropharmacology 29: 193-198.
    • (1990) Neuropharmacology , vol.29 , pp. 193-198
    • McKenna, D.J.1    Repke, D.B.2    Peroutka, S.J.3
  • 37
    • 13244258251 scopus 로고    scopus 로고
    • Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis - a longitudinal study
    • Meincke U, Mörth D, Voss T, Thelen B, Geyer MA, Gouzoulis-Mayfrank E (2004). Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis - a longitudinal study. Eur Arch Psychiatry Clin Neuosci 254: 415-421.
    • (2004) Eur Arch Psychiatry Clin Neuosci , vol.254 , pp. 415-421
    • Meincke, U.1    Mörth, D.2    Voss, T.3    Thelen, B.4    Geyer, M.A.5    Gouzoulis-Mayfrank, E.6
  • 38
    • 0026357347 scopus 로고
    • Effects of antipsychotic drugs on serotonin receptors
    • Meltzer HY, Nash JF (1991). Effects of antipsychotic drugs on serotonin receptors. Pharmacol Rev 43: 587-604.
    • (1991) Pharmacol Rev , vol.43 , pp. 587-604
    • Meltzer, H.Y.1    Nash, J.F.2
  • 40
    • 34547876078 scopus 로고    scopus 로고
    • Three paper-and-pencil tests for speed of information processing: Psychometric properties and correlations with intelligence
    • Neubauer AC, Knorr E (2006). Three paper-and-pencil tests for speed of information processing: Psychometric properties and correlations with intelligence. Intelligence 126: 123-151.
    • (2006) Intelligence , vol.126 , pp. 123-151
    • Neubauer, A.C.1    Knorr, E.2
  • 41
    • 0021304003 scopus 로고
    • Information processing and attentional functioning in the developmental course of schizophrenic disorders
    • Nuechterlein KH, Dawson ME (1984). Information processing and attentional functioning in the developmental course of schizophrenic disorders. Schizophr Bull 10: 160-203.
    • (1984) Schizophr Bull , vol.10 , pp. 160-203
    • Nuechterlein, K.H.1    Dawson, M.E.2
  • 42
    • 0027942724 scopus 로고
    • Informationprocessing abnormalities as neuropsychological vulnerability indicators for schizophrenia
    • Nuechterlein KH, Dawson ME, Green MF (1994). Informationprocessing abnormalities as neuropsychological vulnerability indicators for schizophrenia. Acta Psychiatr Scand 384(Suppl): 71-79.
    • (1994) Acta Psychiatr Scand , vol.384 , Issue.SUPPL. , pp. 71-79
    • Nuechterlein, K.H.1    Dawson, M.E.2    Green, M.F.3
  • 43
    • 0029930333 scopus 로고    scopus 로고
    • 5-HT modulation of auditory and visual sensorimotor gating: II. Effects of the 5-HT2A antagonist MDL 100 907 on disruption of sound and light prepulse inhibition produced by 5-HT agonists in Wistar rats
    • Padich RA, McCloskey TC, Kehne JH (1996). 5-HT modulation of auditory and visual sensorimotor gating: II. Effects of the 5-HT2A antagonist MDL 100 907 on disruption of sound and light prepulse inhibition produced by 5-HT agonists in Wistar rats. Psychopharmacology (Berlin) 124: 107-116.
    • (1996) Psychopharmacology (Berlin) , vol.124 , pp. 107-116
    • Padich, R.A.1    McCloskey, T.C.2    Kehne, J.H.3
  • 45
    • 0028265092 scopus 로고
    • Information-processing deficits and thought disorder in schizophrenia
    • Perry W, Braff DL (1994). Information-processing deficits and thought disorder in schizophrenia. Am J Psychiatry 151: 363-367.
    • (1994) Am J Psychiatry , vol.151 , pp. 363-367
    • Perry, W.1    Braff, D.L.2
  • 46
    • 0033048833 scopus 로고    scopus 로고
    • Sensomotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients
    • Perry W, Geyer MA, Braff DL (1999). Sensomotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients. Arch Gen Psychiatry 56: 227-281.
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 227-281
    • Perry, W.1    Geyer, M.A.2    Braff, D.L.3
  • 47
    • 0035884094 scopus 로고    scopus 로고
    • Sensorimotor gating deficits in bipolar disorder patients with acute psychotic mania
    • Perry W, Minassian A, Feifel D, Braff DL (2001). Sensorimotor gating deficits in bipolar disorder patients with acute psychotic mania. Biol Psychiatry 50: 418-424.
    • (2001) Biol Psychiatry , vol.50 , pp. 418-424
    • Perry, W.1    Minassian, A.2    Feifel, D.3    Braff, D.L.4
  • 48
    • 33644611674 scopus 로고    scopus 로고
    • Sensorimotor gating and habituation of the startle response in schizophrenic patients randomly treated with amisulpride or olanzapine
    • Quednow BB, Wagner M, Westheide J, Beckmann K, Bliesener N, Maier W et al (2006). Sensorimotor gating and habituation of the startle response in schizophrenic patients randomly treated with amisulpride or olanzapine. Biol Psychiatry 59: 536-545.
    • (2006) Biol Psychiatry , vol.59 , pp. 536-545
    • Quednow, B.B.1    Wagner, M.2    Westheide, J.3    Beckmann, K.4    Bliesener, N.5    Maier, W.6
  • 49
    • 0036942585 scopus 로고    scopus 로고
    • Effects of ayahuasca on sensory and sensorimotor gating in humans as measured by P50 suppression and prepulse inhibition of the startle reflex, respectively
    • Riba J, Rodriguez-Fornells A, Barbanoj MJ (2002). Effects of ayahuasca on sensory and sensorimotor gating in humans as measured by P50 suppression and prepulse inhibition of the startle reflex, respectively. Psychopharmacology (Berlin) 165: 18-28.
    • (2002) Psychopharmacology (Berlin) , vol.165 , pp. 18-28
    • Riba, J.1    Rodriguez-Fornells, A.2    Barbanoj, M.J.3
  • 50
    • 3142704173 scopus 로고    scopus 로고
    • Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders
    • Roth BL, Hanizavareh SM, Blum AE (2004). Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders. Psychopharmacology 174: 17-24.
    • (2004) Psychopharmacology , vol.174 , pp. 17-24
    • Roth, B.L.1    Hanizavareh, S.M.2    Blum, A.E.3
  • 51
    • 0033871171 scopus 로고    scopus 로고
    • Automatic and controlled attentional processes in startle eyeblink modification: Effects of habituation of the prepulse
    • Schell AM, Wynn JK, Dawson ME, Sinaii N, Niebala CB (2000). Automatic and controlled attentional processes in startle eyeblink modification: effects of habituation of the prepulse. Psychophysiology 37: 409-417.
    • (2000) Psychophysiology , vol.37 , pp. 409-417
    • Schell, A.M.1    Wynn, J.K.2    Dawson, M.E.3    Sinaii, N.4    Niebala, C.B.5
  • 52
    • 0028244826 scopus 로고
    • Multiple serotonin receptor subtypes modulate prepulse inhibition of the startle response in rats
    • Sipes TE, Geyer MA (1994). Multiple serotonin receptor subtypes modulate prepulse inhibition of the startle response in rats. Neuropharmacology 33: 441-448.
    • (1994) Neuropharmacology , vol.33 , pp. 441-448
    • Sipes, T.E.1    Geyer, M.A.2
  • 53
    • 0028791321 scopus 로고
    • DOI disruption of prepulse inhibition of startle in the rat is mediated by 5-HT2A and not by 5-HT2C receptors
    • Sipes TE, Geyer MA (1995). DOI disruption of prepulse inhibition of startle in the rat is mediated by 5-HT2A and not by 5-HT2C receptors. Behav Pharmacol 6: 839-842.
    • (1995) Behav Pharmacol , vol.6 , pp. 839-842
    • Sipes, T.E.1    Geyer, M.A.2
  • 54
    • 0030750579 scopus 로고    scopus 로고
    • DOI disrupts prepulse inhibition of startle in rats via 5-HT2A receptors in the ventral pallidum
    • Sipes TE, Geyer MA (1997). DOI disrupts prepulse inhibition of startle in rats via 5-HT2A receptors in the ventral pallidum. Brain Res 761: 97-104.
    • (1997) Brain Res , vol.761 , pp. 97-104
    • Sipes, T.E.1    Geyer, M.A.2
  • 56
    • 34547854282 scopus 로고    scopus 로고
    • StatSoft Inc, 2005, STATISTICA data analysis software system, version 7.1, OK
    • StatSoft Inc. (2005). STATISTICA (data analysis software system), version 7.1 www.statsoft.com. Tulsa, OK.
  • 57
    • 0033938877 scopus 로고    scopus 로고
    • Animal models of deficient sensorimotor gating: What we know, what we think we know, and what we hope to know soon
    • Swerdlow NR, Braff DL, Geyer MA (2000). Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon. Behav Pharmacol 11: 185-204.
    • (2000) Behav Pharmacol , vol.11 , pp. 185-204
    • Swerdlow, N.R.1    Braff, D.L.2    Geyer, M.A.3
  • 58
    • 0028371468 scopus 로고
    • Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients
    • Swerdlow NR, Braff DL, Taaid N, Geyer MA (1994). Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch Gen Psychiatry 51: 139-154.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 139-154
    • Swerdlow, N.R.1    Braff, D.L.2    Taaid, N.3    Geyer, M.A.4
  • 59
    • 0031720755 scopus 로고    scopus 로고
    • Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia
    • Swerdlow NR, Geyer MA (1998). Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr Bull 24: 285-301.
    • (1998) Schizophr Bull , vol.24 , pp. 285-301
    • Swerdlow, N.R.1    Geyer, M.A.2
  • 60
    • 0034927844 scopus 로고    scopus 로고
    • Neural circuit regulation of prepulse inhibition of startle in the rat: Current knowledge and future challenges
    • Swerdlow NR, Geyer MA, Braff DL (2001). Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berlin) 156: 194-215.
    • (2001) Psychopharmacology (Berlin) , vol.156 , pp. 194-215
    • Swerdlow, N.R.1    Geyer, M.A.2    Braff, D.L.3
  • 61
    • 0031568885 scopus 로고    scopus 로고
    • Changes in sensorimotor inhibition across the menstrual cycle: Implications for neuropsychiatric disorders
    • Swerdlow NR, Hartman PL, Auerbach PP (1996). Changes in sensorimotor inhibition across the menstrual cycle: implications for neuropsychiatric disorders. Biol Psychiatry 41: 452-460.
    • (1996) Biol Psychiatry , vol.41 , pp. 452-460
    • Swerdlow, N.R.1    Hartman, P.L.2    Auerbach, P.P.3
  • 62
    • 0031855523 scopus 로고    scopus 로고
    • Advances and pathophysiological models of hallucinogen drug actions in humans: A preamble to schizophrenia research
    • Vollenweider FX (1998). Advances and pathophysiological models of hallucinogen drug actions in humans: a preamble to schizophrenia research. Pharmacopsychiatry 31: 92-103.
    • (1998) Pharmacopsychiatry , vol.31 , pp. 92-103
    • Vollenweider, F.X.1
  • 63
    • 0842277272 scopus 로고    scopus 로고
    • Brain mechanisms of hallucinogens and entactogens
    • Vollenweider FX (2001). Brain mechanisms of hallucinogens and entactogens. Dialog Clin Neurosci 3: 265-279.
    • (2001) Dialog Clin Neurosci , vol.3 , pp. 265-279
    • Vollenweider, F.X.1
  • 64
    • 0031783570 scopus 로고    scopus 로고
    • Psychological and cardiovascular effects and short-term sequelae of MDMA ('Ecstasy') on MDMA-naive healthy volunteers
    • Vollenweider FX, Gamma A, Liechti ME, Huber T (1998). Psychological and cardiovascular effects and short-term sequelae of MDMA ('Ecstasy') on MDMA-naive healthy volunteers. Neuropsychopharmacology 19: 241-251.
    • (1998) Neuropsychopharmacology , vol.19 , pp. 241-251
    • Vollenweider, F.X.1    Gamma, A.2    Liechti, M.E.3    Huber, T.4
  • 65
    • 0035891880 scopus 로고    scopus 로고
    • A systems model of altered consciousness: Integrating natural and drug-induced psychoses
    • Vollenweider FX, Geyer MA (2001). A systems model of altered consciousness: Integrating natural and drug-induced psychoses. Brain Res Bull 56: 495-507.
    • (2001) Brain Res Bull , vol.56 , pp. 495-507
    • Vollenweider, F.X.1    Geyer, M.A.2
  • 66
    • 0030916849 scopus 로고    scopus 로고
    • Positron emission tomography and fluorodeoxyglucose studies of metabolic hyperfrontality and psychopathology in the psilocybin model of psychosis
    • Vollenweider FX, Leenders KL, Scharfetter C, Maguire P, Stadelmann O, Angst J (1997). Positron emission tomography and fluorodeoxyglucose studies of metabolic hyperfrontality and psychopathology in the psilocybin model of psychosis. Neuropsychopharmacology 16: 357-372.
    • (1997) Neuropsychopharmacology , vol.16 , pp. 357-372
    • Vollenweider, F.X.1    Leenders, K.L.2    Scharfetter, C.3    Maguire, P.4    Stadelmann, O.5    Angst, J.6
  • 67
    • 0032924820 scopus 로고    scopus 로고
    • Opposite effects of 3,4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans
    • Vollenweider FX, Remensberger S, Hell D, Geyer MA (1999a). Opposite effects of 3,4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans. Psychopharmacology 143: 365-372.
    • (1999) Psychopharmacology , vol.143 , pp. 365-372
    • Vollenweider, F.X.1    Remensberger, S.2    Hell, D.3    Geyer, M.A.4
  • 68
    • 0033136980 scopus 로고    scopus 로고
    • 5-HT modulation of dopamine release in basal ganglia in psilocybin-induced psychosis in man: A PET study with [11C]raclopride
    • Vollenweider FX, Vontobel P, Hell D, Leenders KL (1999b). 5-HT modulation of dopamine release in basal ganglia in psilocybin-induced psychosis in man: A PET study with [11C]raclopride. Neuropsychopharmacology 20: 424-433.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 424-433
    • Vollenweider, F.X.1    Vontobel, P.2    Hell, D.3    Leenders, K.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.