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Volumn 22, Issue 7, 2007, Pages 1882-1890

Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauci-immune glomerulonephritis

Author keywords

BMP 7 antagonist; Crescentic glomerulonephritis; Epithelial mesenchymal transition (EMT); Gremlin; Smad; TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BINDING PROTEIN; CD68 ANTIGEN; CONNECTIVE TISSUE GROWTH FACTOR; CYCLINE; CYTOKERATIN; GREMLIN; MESSENGER RNA; OSTEOGENIC PROTEIN 1; SMAD2 PROTEIN; SYNAPTOPODIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 34547851691     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfm145     Document Type: Article
Times cited : (47)

References (20)
  • 1
    • 0034708483 scopus 로고    scopus 로고
    • Biosynthesis, post-translation modification, and functional characterization of Drm/Gremlin
    • Topol LZ, Bardot B, Zhang Q et al. Biosynthesis, post-translation modification, and functional characterization of Drm/Gremlin J Biol Chem 2000; 275: 8785-8793
    • (2000) J Biol Chem , vol.275 , pp. 8785-8793
    • Topol, L.Z.1    Bardot, B.2    Zhang, Q.3
  • 2
    • 33745435247 scopus 로고    scopus 로고
    • Recapitulation of embryological programmes in renal fibrosis The importance of epithelial cell plasticity and developmental genes
    • Roxburgh SA, Murphy M, Pollock CA, Brazil DF Recapitulation of embryological programmes in renal fibrosis The importance of epithelial cell plasticity and developmental genes. Nephron Physiol 2006; 103: 139-148
    • (2006) Nephron Physiol , vol.103 , pp. 139-148
    • Roxburgh, S.A.1    Murphy, M.2    Pollock, C.A.3    Brazil, D.F.4
  • 3
    • 0034616419 scopus 로고    scopus 로고
    • IHG-2, a mesangia cell gene induced by high glucose, is human gremlin. Regulation by extracellular glucose concentration, cyclic mechanical strair and transforming growth factor-beta 1
    • McMahon R, Murphy M, Clarkson M et al. IHG-2, a mesangia cell gene induced by high glucose, is human gremlin. Regulation by extracellular glucose concentration, cyclic mechanical strair and transforming growth factor-beta 1. J Biol Chem 2000; 275: 9901-9904
    • (2000) J Biol Chem , vol.275 , pp. 9901-9904
    • McMahon, R.1    Murphy, M.2    Clarkson, M.3
  • 4
    • 20444364531 scopus 로고    scopus 로고
    • Expression of gremlin, BMP antagonist, in human diabetic nephropathy
    • Dolan V, Murphy M, Sadlier D et al. Expression of gremlin, BMP antagonist, in human diabetic nephropathy. Am Kidney Dis 2005; 45: 1034-1039
    • (2005) Am Kidney Dis , vol.45 , pp. 1034-1039
    • Dolan, V.1    Murphy, M.2    Sadlier, D.3
  • 5
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112: 1776-1784
    • (2003) J Clin Invest , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 6
    • 33644864525 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 and the kidney: Current concepts and open questions
    • Zeisberg M. Bone morphogenic protein-7 and the kidney: Current concepts and open questions. Nephrol Dial Transplant 2006; 21: 568-573
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 568-573
    • Zeisberg, M.1
  • 7
    • 0032738399 scopus 로고    scopus 로고
    • Glomerular epithelial-myofibroblast transdifferentiation in the evolution of glomerular crescent formation
    • Ng Y-Y, Fan J-M, Mu W et al. Glomerular epithelial-myofibroblast transdifferentiation in the evolution of glomerular crescent formation. Nephrol Dial Transplant 1999; 14: 2860-2872
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 2860-2872
    • Y-Y, N.1    Fan, J.-M.2    Mu, W.3
  • 8
    • 0036373785 scopus 로고    scopus 로고
    • Mechanisms and kinetics of Bowman's epithelial-myofibroblast transdifferentiation in the formation of glomerular crescents
    • Fujigaki Y, Sun DF, Fujimoto T et al. Mechanisms and kinetics of Bowman's epithelial-myofibroblast transdifferentiation in the formation of glomerular crescents. Nephron 2002; 92: 203-212
    • (2002) Nephron , vol.92 , pp. 203-212
    • Fujigaki, Y.1    Sun, D.F.2    Fujimoto, T.3
  • 9
    • 0041883687 scopus 로고    scopus 로고
    • Glomerular epithelial-mesenchymal transdifferentiation in Pauci-immune crescentic glomerunephritis
    • Bariéty J, Hill GS, Mandet Ch et al. Glomerular epithelial-mesenchymal transdifferentiation in Pauci-immune crescentic glomerunephritis. Nephrol Dial Transplant 2003; 18: 1777-1784
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 1777-1784
    • Bariéty, J.1    Hill, G.S.2    Mandet, C.3
  • 10
    • 0033995738 scopus 로고    scopus 로고
    • Overexpression of chemokines, fibrogenic cytokines and myofibroblasts in human membranous nephropathy
    • Mezzano S, Droguett A, Burgos ME et al. Overexpression of chemokines, fibrogenic cytokines and myofibroblasts in human membranous nephropathy. Kidney Int 2000; 57: 147-158
    • (2000) Kidney Int , vol.57 , pp. 147-158
    • Mezzano, S.1    Droguett, A.2    Burgos, M.E.3
  • 11
    • 0036387022 scopus 로고    scopus 로고
    • Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-β-induced fibronectin in mesangial cells
    • Isono M, Chen Sh, Hong SW et al. Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-β-induced fibronectin in mesangial cells. Bioch Bioph Res Comm 2002; 296: 1356-1365
    • (2002) Bioch Bioph Res Comm , vol.296 , pp. 1356-1365
    • Isono, M.1    Chen, S.2    Hong, S.W.3
  • 12
    • 0034740805 scopus 로고    scopus 로고
    • Tubular NFkβ and AP-1 activation in human proteinuric renal disease
    • Mezzano S, Barda M, Droguett A et al. Tubular NFkβ and AP-1 activation in human proteinuric renal disease. Kidney Int 2001; 60: 1366-1377
    • (2001) Kidney Int , vol.60 , pp. 1366-1377
    • Mezzano, S.1    Barda, M.2    Droguett, A.3
  • 13
    • 0347993932 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in renal fibro-genesis: Pathologic significance, molecular mechanism and therapeutic intervention
    • Liu Y. Epithelial to mesenchymal transition in renal fibro-genesis: pathologic significance, molecular mechanism and therapeutic intervention. J Am Soc Nephrol 2004; 15: 1-12
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1-12
    • Liu, Y.1
  • 14
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H et al. BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 2003; 9: 964-968
    • (2003) Nat Med , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3
  • 15
    • 0034758712 scopus 로고    scopus 로고
    • Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy
    • Wang Sh-N, Lapage J, Hirschberg R. Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy. J Am Soc Nephrol 2001; 12: 2392-2399
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2392-2399
    • Wang, S.-N.1    Lapage, J.2    Hirschberg, R.3
  • 16
    • 0036786834 scopus 로고    scopus 로고
    • TGF-β signaling in renal disease
    • Bottinger E, Bitzer M. TGF-β signaling in renal disease. J Am Soc Nephrol 2002, 13: 2600-2610
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2600-2610
    • Bottinger, E.1    Bitzer, M.2
  • 17
    • 0036841123 scopus 로고    scopus 로고
    • Inhibitory Smads and TGF-β Signaling in glomerular cells
    • Schiffer M, Schiffer LE, Gupta A et al. Inhibitory Smads and TGF-β Signaling in glomerular cells. J Am Soc Nephrol 2002; 13: 2657-5666
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2657-5666
    • Schiffer, M.1    Schiffer, L.E.2    Gupta, A.3
  • 18
    • 2342512104 scopus 로고    scopus 로고
    • Role of connective tissue growth factor in renal tubular epithelial-myofibroblast transdifferentiation and extracellular matrix accumulation in vitro
    • Zhang Ch, Men GX, Zhu Zh et al. Role of connective tissue growth factor in renal tubular epithelial-myofibroblast transdifferentiation and extracellular matrix accumulation in vitro. Life Sciences 2004; 75: 367-379
    • (2004) Life Sciences , vol.75 , pp. 367-379
    • Zhang, C.1    Men, G.X.2    Zhu, Z.3
  • 19
    • 0031959237 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor in human renal fibrosis
    • Ito Y, Aten J, Bende R et al. Expression of connective tissue growth factor in human renal fibrosis. Kidney Int 1998; 53: 853-861
    • (1998) Kidney Int , vol.53 , pp. 853-861
    • Ito, Y.1    Aten, J.2    Bende, R.3
  • 20
    • 0242581407 scopus 로고    scopus 로고
    • Connective tissue growth factor participates in scar formation of crescentic glomerulonephritis
    • Kanemoto K, Usui J, Tomari SH et al. Connective tissue growth factor participates in scar formation of crescentic glomerulonephritis. Lab Invest 2003; 83: 161-1625
    • (2003) Lab Invest , vol.83 , pp. 161-1625
    • Kanemoto, K.1    Usui, J.2    Tomari, S.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.