Overexpression of chemokines, fibrogenic cytokines, and myofibroblasts in human membranous nephropathy

Kidney International

Volumn 57, Issue 1, 2000, Pages 147-158

  Mezzano, Sergio A ^a,b   Droguett, M Alejandra ^a,b   Burgos, M Eugenia ^a,b   Ardiles, Leopoldo G ^a,b   Aros, Claudio A ^a,b   Caorsi, Italo ^a,b   Egido, Jesús ^a,b  

^a UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Growth factors; Idiopathic membranous nephropathy; Monocyte chemoattractant protein 1; Osteopontin; Proteinuria

Indexed keywords

ALPHA ACTIN; CD4 ANTIGEN; CD68 ANTIGEN; CD8 ANTIGEN; CHEMOKINE; CYTOKINE; GROWTH FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPONTIN; PLATELET DERIVED GROWTH FACTOR BB; RANTES; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; CELL ACTIVATION; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; INFLAMMATION; KIDNEY BIOPSY; KIDNEY TUBULE; MALE; MEMBRANOUS GLOMERULONEPHRITIS; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEINURIA; T LYMPHOCYTE ACTIVATION;

EID: 0033995738     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00830.x     Document Type: Article

References (43)

1. 1. Remuzzi G, Ruggenenti P, Begnini A: Understanding the nature of renal disease progression. Kidney Int 51:2-15, 1997
2. 2. Gansevoort RT, Navis GJ, Wapstra FH, De Jong PE, De Zeeuw D: Proteinuria and progression of renal disease: Therapeutic implications. Curr Opin Nephrol Hypertens 6:133-140, 1997
3. 3. Jungers P, Hannedouche T, Itakura Y, Albouze G, Descamps-Latscha B, Mann NK: Progression rate to end-stage renal failure in non diabetic kidney diseases: A multivariate analysis of determinant factors. Nephrol Dial Transplant 10:1353-1360, 1995
4. 4. The Gisen Group (Gruppo Italiano Di Studi Epidemiologici In Nefrologia): Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non diabetic nephropathy. Lancet 349:1857-1863, 1997
5. 5. Bohle A, Wehrmann M, MacKensen-Haen S, Gise HV, Mickeler E, Xiao TC, Muller C, Muller GA: Pathogenesis of chronic renal failure in primary glomerulonephritis. Nephrol Dial Transplant S 3:4-12, 1994
6. 6. Wehrmann M, Bohle A, Bogenschutz O, Eissele R, Freislederer A, Ohlschlegel C, Schumm G, Batz C, Gartner H-V: Long term prognosis of chronic idiopathic membranous glomerulonephritis. Clin Nephrol 31:67-76, 1989
7. 7. MacKensen-Haen R, Eissele R, Bohle A: Contribution on the correlation between morphometric parameters gained from the renal cortex and renal function in IgA nephritis. Lab Invest 59:239-244, 1988
8. 8. MacKensen-Haen S, Bohle A, Christensen J, Wehrmann M, Kendziorra H, Kokot F: The consequences for renal function of widening of the interstitium and changes in the tubular epithelium of renal cortex and outer medulla in various renal diseases. Clin Nephrol 37:70-77, 1992
9. 9. Nath KA: Tubulointerstitial disease as a major determinant of progressive renal injury. Am J Kidney Dis 20:1-17, 1992
10. 10. Eddy AA, Giachelli CM, McCulloch L, Liu E: Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria. Kidney Int 47:1546-1557, 1995
11. 11. Wang Y, Chen J, Chen L, Tay Y-C, Rangan GK, Harris DCH: Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein. J Am Soc Nephrol 8:1537-1545, 1997
12. 12. Abbate M, Zoja C, Corna D, Capitano M, Bertani T, Remuzzi G: In progressive nephropathies, overload of tubular cells with filtered proteins translates glomerular permeability dysfunction into cellular signals of interstitial inflammation. J Am Soc Nephrol 9:1213-1224, 1998
13. 13. Ong AC, Fine LG: Tubular-derived growth factors and cytokines in the pathogenesis of tubulointerstitial fibrosis: Implications for human renal disease progression. Am J Kidney Dis 23:205-209, 1994
14. 14. Eddy AA, McCulloch L, Adams J, Liu E: Interstitial nephritis induced by protein-overload proteinuria. Am J Pathol 135:719-733, 1989
15. 15. Heeger P, Wolf G, Meyers C, Sun MJ, O'Farrell SC, Krensky AM, Neilson EG: Isolation and characterization of cDNA from renal tubular epithelium encoding murine RANTES. Kidney Int 41:220-225, 1992
16. 16. Border WA, Noble NA: TGF-β in kidney fibrosis: A target for gene therapy. Kidney Int 51:1388-1396, 1997
17. 17. Desmoulière A, Geinoz A, Gabbiani F, Gabbiani G: Transforming growth factor-β1 induces α-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 122:103-111, 1993
18. 18. Tang WW, Ulich TR, Lacey DL, Hill DC, Qi M, Kaufman SA, Van Gy Tarpley JE, Yee JS: Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis. Am J Pathol 148:1169-1180, 1996
19. 19. Okada H, Strutz F, Danoff TM, Neilson EG: Possible pathogenesis of renal fibrosis. Kidney Int 49(Suppl 54):S37-S38, 1996
20. 20. Wasserstein AG: Membranous glomerulonephritis. J Am Soc Nephrol 8:664-674, 1997
21. 21. Reichert LJ, Koene RA, Wetzels JF: Prognostic factors in idiopathic membranous nephropathy. Am J Kidney Dis 31:1-11, 1998
22. 22. Grandaliano G, Gesualdo L, Ranieri E, Monno R, Montinaro V, Marra F, Schena FP: Monocyte chemotactic peptide-1 expression in acute and chronic human nephritides: A pathogenetic role in interstitial monocytes recruitment. J Am Soc Nephrol 7:906-913, 1996
23. 23. Pichler R, Giachelli CM, Lombardi D, Pippin J, Gordon K, Alpers CE, Schwartz SM, Johnson RJ: Tubulointerstitial disease in glomerulonephritis: Potential role of osteopontin (uropontin). Am J Pathol 144:915-926, 1994
24. 24. Lloyd C, Gutierrez-Ramos JC: The role of chemokines in tissue inflammation and autoimmunity in renal diseases. Curr Opin Nephrol Hypertens 7:281-287, 1998
25. 25. Giachelli CM, Schwartz SM, Liaw L: Molecular and cellular biology of osteopontin: Potential role in cardiovascular disease. Trends Cardiovasc Med 5:88-95, 1995
26. 26. Schlondorff D, Nelson PJ, Luckow B, Banas B: Chemokines and renal disease. Kidney Int 51:610-621, 1997
27. 27. Gesualdo L, Grandaliano G, Ranieri E, Monno R, Montinaro V, Manno C, Schena FP: Monocyte recruitment in cryoglobulinemic membranoproliferative glomerulonephritis: A pathogenic role for monocyte chemotactic peptide-1. Kidney Int 51:155-163, 1997
28. 28. Prodjosudjadi W, Gerritsma JS, Vanes LA, Daha MR, Brujin JA: Monocyte chemoattractant protein-1 in normal and diseased human kidneys: An immunohistochemical analysis. Clin Nephrol 44:148-155, 1995
29. 29. Wada T, Yokoyama H, Su S-B, Mukaida N, Iwano M, Dohi K, Takahashi Y, Sasaki T, Furuichi K, Segawa C, Hisada I, Ohta S, Takasawa K, Kobayashi K-I, Matsushima K: Monitoring urinary levels of monocyte chemotactic and activating factor reflects disease activity of lupus nephritis. Kidney Int 49:761-767, 1996
30. 30. Cockwell P, Howie AJ, Adu D, Savage CO: In situ analysis of C-C chemokine mRNA in human glomerulonephritis. Kidney Int 54:827-836, 1998
31. 31. Remuzzi G, Zoja C, Gagliardini E, Corna D, Abbate M, Begnini A: Combining an antiproteinuric approach with mycophenolate mofetil fully suppresses progressive nephropathy of experimental animals. J Am Soc Nephrol 10:1542-1549, 1999
32. 32. Risdon RA, Sloper JC, De Wardener HE: Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. Lancet 2:363-366, 1968
33. 33. Schainuck LI, Stricker GE, Cutler RE, Benditt EP: Structural-functional correlations in renal disease. II. The correlations. Hum Pathol 1:631-641, 1970
34. 34. Yamamoto T, Noble NA, Miller DE, Border WA: Sustained expression of TGF-β1 underlies development of progressive kidney fibrosis. Kidney Int 45:916-927, 1994
35. 35. Gabbiani G: The biology of the myofibroblast. Kidney Int 41:530-532, 1992
36. 36. Tang WW, Van Gy Qim: Myofibroblast and α1 (III) collagen expression in experimental tubulointerstitial nephritis. Kidney Int 51:926-931, 1997
37. 37. Stein-Oakley AN, Maguire JA, Dowling J, Perry G, Thomson NM: Altered expression of fibrogenic growth factors in IgA nephropathy and focal and segmental glomerulosclerosis. Kidney Int 51:195-204, 1997
38. 38. Ito J, Aten J, Bende RJ, Oemar BS, Rabelink TJ, Weening JJ, Glodschmeding R: Expression of connective tissue growth factor in human renal fibrosis. Kidney Int 53:853-861, 1998
39. 39. Roberts IS, Burrows C, Shanks JH, Venning M, McWilliam LJ: Interstitial myofibroblasts: Predictors of progression in membranous nephropathy. J Clin Pathol 50:123-127, 1997
40. 40. Alpers CE, Hudkins KL, Floege J, Johnson RJ: Human renal cortical interstitial cells with some features of smooth muscle cells participate in tubulointerstitial and crescentic glomerular injury. J Am Soc Nephrol 5:201-210, 1994
41. 41. Goumenos DS, Brown CB, Shortland JEL, Nahas AM: Myofibroblasts, predictors of progression of mesangial IgA nephropathy? Nephrol Dial Transplant 9:1418-1425, 1994
42. 42. Kliem V, Johnson RJ, Alpers CE, Yoshimura A, Couser WG, Koch KM, Floege J: Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats. Kidney Int 49:666-678, 1996
43. 43. Diamond JR, Van Goor H, Ding G, Engelmyer E: Myofibroblasts in experimental hydronephrosis. Am J Pathol 146:121-129, 1995