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We previously synthesized the E-rings through the aldol reactionlmetathesis sequence.However, the stereoselectivity of the previous route was modest.
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34547831643
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note
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The numbering of compounds in Schemes 1 and 2 corresponds to that of CTX1B (1).
-
-
-
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45
-
-
34547825415
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-
note
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The numbering of compounds in Scheme 3 corresponds to that of CTX3C (2).
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55
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34547825412
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2 was not present as the additive, the yield of 21 was significantly decreased.
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60
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84986437005
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