Attenuating 5α-pregnane-3α-ol-20-one formation in the hippocampus of female rats increases pentylenetetrazole-induced seizures

Epilepsy and Behavior

Volumn 6, Issue 2, 2005, Pages 140-146

  Rhodes, Madeline E ^a   Frye, Cheryl A ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

3 ,5 THP; 5 Reductase; Animal model; Epilepsy; Finasteride; Progesterone

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ALCOHOL; BETA CYCLODEXTRIN; FINASTERIDE; GESTAGEN; PENTETRAZOLE; PROGESTERONE; SESAME SEED OIL; DEOXYCORTICOSTERONE; DRUG DERIVATIVE; ENZYME INHIBITOR; TETRAHYDRODEOXYCORTICOSTERONE;

ANALYSIS OF VARIANCE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ANTICONVULSANT THERAPY; ARTICLE; ATTENUATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG METABOLISM; FEMALE; FREQUENCY ANALYSIS; HIPPOCAMPUS; HORMONE DETERMINATION; LATENT PERIOD; NONHUMAN; OVARIECTOMY; PROGESTERONE BLOOD LEVEL; PROGESTERONE METABOLISM; PROGESTERONE SYNTHESIS; RADIOIMMUNOASSAY; RAT; TONIC SEIZURE; ANIMAL; BLOOD; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DRUG ADMINISTRATION ROUTE; DRUG EFFECT; DRUG INTERACTION; LONG EVANS RAT; METABOLISM; METHODOLOGY; SEIZURE;

ANIMALS; BEHAVIOR, ANIMAL; DESOXYCORTICOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; DRUG INTERACTIONS; ENZYME INHIBITORS; FEMALE; FINASTERIDE; HIPPOCAMPUS; OVARIECTOMY; PENTYLENETETRAZOLE; PROGESTERONE; RADIOIMMUNOASSAY; RATS; RATS, LONG-EVANS; SEIZURES;

EID: 13844275584     PISSN: 15255050     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yebeh.2004.11.019     Document Type: Article

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