Green tea polyphenol extract regulates the expression of genes involved in glucose uptake and insulin signaling in rats fed a high fructose diet

Journal of Agricultural and Food Chemistry

Volumn 55, Issue 15, 2007, Pages 6372-6378

  Cao, Heping ^a   Hininger Favier, Isabelle ^b   Kelly, Meghan A ^a   Benaraba, Rachida ^b   Dawson, Harry D ^a   Coves, Sara ^c   Roussel, Anne M ^b   Anderson, Richard A ^a  

^a BELTSVILLE HUMAN NUTRITION RESEARCH CENTER   (United States)

^b UNIV GRENOBLE ALPES   (France)

^c UNILEVER RESEARCH   (United Kingdom)

Author keywords

Diabetes; Fructose rich diet; Glucose transporter; Green tea; Insulin signaling pathway; Obesity; Polyphenol extract, rat

Indexed keywords

FLAVONOID; GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; MESSENGER RNA; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOLS; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; POLYMERASE CHAIN REACTION; RAT; SIGNAL TRANSDUCTION; TEA; WISTAR RAT;

ANIMALS; FLAVONOIDS; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; INSULIN; MALE; PHENOLS; PLANT EXTRACTS; POLYMERASE CHAIN REACTION; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; TEA;

ANIMALIA; RATTUS;

EID: 34547730995     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf070695o     Document Type: Article

References (52)

1. Dandona, P.; Aljada, A.; Bandyopadhyay, A. Inflammation: The link between insulin resistance, obesity and diabetes. Trends Immunol. 2004, 25, 4-7.
2. Eckel, R. H.; Grundy, S. M.; Zimmet, P. Z. The metabolic syndrome. Lancet 2005, 365, 1415-1428.
3. Hotamisligil, G. S. Inflammation and metabolic disorders. Nature 2006, 444, 860-867.
4. Stumvoll, M.; Goldstein, B. J.; van Haeften, T. W. Type 2 diabetes: Principles of pathogenesis and therapy. Lancet 2005, 365, 1333-1346.
5. Greenberg, A. S.; Obin, M. S. Obesity and the role of adipose tissue in inflammation and metabolism. Am. J. Clin. Nutr. 2006, 83, 461S-465S.
6. Carter, J. S.; Pugh, J. A.; Monterrosa, A. Non-insulin-dependent diabetes mellitus in minorities in the United States. Ann. Intern. Med. 1996, 125, 221-232.
7. Gross, L. S.; Li, L.; Ford, E. S.; Liu, S. Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: An ecologic assessment. Am. J. Clin. Nutr. 2004, 79, 774-779.
8. Gray, A. M.; Flatt, P. R. Pancreatic and extra-pancreatic effects of the traditional anti-diabetic plant, Medicago sativa (lucerne). Br. J. Nutr. 1997, 78, 325-334.
9. Dixon, R. A.; Xie, D. Y.; Sharma, S. B. Proanthocyanidins - A final frontier in flavonoid research? New Phytol. 2005, 165, 9-28.
10. Prior, R. L.; Gu, L. Occurrence and biological significance of proanthocyanidins in the American diet. Phytochemistry 2005, 66, 2264-2280.
11. Yang, C. S.; Landau, J. M.; Huang, M. T.; Newmark, H. L. Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu. Rev. Nutr. 2001, 21, 381-406.
12. McKay, D. L.; Blumberg, J. B. The role of tea in human health: an update. J. Am. Coll. Nutr. 2002, 21, 1-13.
13. Rodriguez, S. K.; Guo, W.; Liu, L.; Band, M. A.; Paulson, E. K.; Meydani, M. Green tea catechin, epigallocatechin-3-gallate, inhibits vascular endothelial growth factor angiogenic signaling by disrupting the formation of a receptor complex. Int. J. Cancer 2006, 118, 1635-1644.
14. Kao, Y. H.; Chang, H. H.; Lee, M. J.; Chen, C. L. Tea, obesity, and diabetes. Mol. Nutr. Food Res. 2006, 50, 188-210.
15. Wolfram, S.; Wang, Y.; Thielecke, F. Anti-obesity effects of green tea: From bedside to bench. Mol. Nutr. Food Res. 2006, 50, 176-187.
16. Anderson, R. A.; Polansky, M. M. Tea enhances insulin activity. J. Agric. Food Chem. 2002, 50, 7182-7186.
17. Broadhurst, C. L.; Polansky, M. M.; Anderson, R. A. Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J. Agric. Food Chem. 2000, 48, 849-852.
18. Wu, L. Y.; Juan, C. C.; Ho, L. T.; Hsu, Y. P.; Hwang, L. S. Effect of green tea supplementation on insulin sensitivity in Sprague-Dawley rats. J. Agric. Food Chem. 2004, 52, 643-648.
19. Li, C.; Allen, A.; Kwagh, J.; Doliba, N. M.; Qin, W.; Najafi, H.; Collins, H. W.; Matschinsky, F. M.; Stanley, C. A.; Smith, T. J. Green tea polyphenols modulate insulin secretion by inhibiting glutamate dehydrogenase. J. Biol. Chem. 2006, 281, 10214-10221.
20. Anton, S.; Melville, L.; Rena, G. Epigallocatechin gallate (EGCG) mimics insulin action on the transcription factor FOXOIa and elicits cellular responses in the presence and absence of insulin. Cell Signal. 2007, 19, 378-383.
21. Cao, H.; Polansky, M. M.; Blackshear, P. J.; Anderson, R. A. Insulin and cinnamon polyphenols increase the amount of insulin receptor b, glucose transporter 4, and anti-inflammatory protein tristetraprolin in mouse 3T3-L1 adipocytes [abstract]. FASEB J. 2006, 20, A93.
22. Cao, H.; Kelly, M. A.; Kari, F.; Dawson, H. D.; Urban, J. F., Jr.; Coves, S.; Roussel, A. M.; Anderson, R. A. Green tea increases anti-inflammatory tristetraprolin and decreases proinflammatory tumor necrosis factor mRNA levels in rats. J. Inflammation (London) 2007, 4, 1.
23. Lai, W. S.; Stumpo, D. J.; Blackshear, P. J. Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein. J. Biol. Chem. 1990, 265, 16556-16563.
24. Ryu, O. H.; Lee, J.; Lee, K. W.; Kim, H. Y.; Seo, J. A.; Kim, S. G.; Kim, N. H.; Baik, S. H.; Choi, D. S.; Choi, K. M. Effects of green tea consumption on inflammation, insulin resistance and pulse wave velocity in type 2 diabetes patients. Diabetes Res. Clin. Pract. 2006, 71, 356-358.
25. Faure, P.; Rossini, E.; Wiernsperger, N.; Richard, M. J.; Favier, A.; Halimi, S. An insulin sensitiver improves the free radical defense system potential and insulin sensitivity in high fructose-fed rats. Diabetes 1999, 48, 353-357.
26. Wu, L. Y.; Juan, C. C.; Hwang, L. S.; Hsu, Y. P.; Ho, P. H.; Ho, L. T. Green tea supplementation ameliorates insulin resistance and increases glucose transporter IV content in a fructose-fed rat model. Eur. J. Nutr. 2004, 43, 116-124.
27. Cao, H.; Polansky, M. M.; Anderson, R. A. Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes. Arch. Biochem. Biophys. 2007, 459, 214-222.
28. Shepherd, P. R.; Kahn, B. B. Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus. N. Engl. J. Med. 1999, 341, 248-257.
29. Taha, C.; Klip, A. The insulin signaling pathway. J. Membr. Biol. 1999, 169, 1-12.
30. Anderson, R. A.; Hininger, I.; Coves, S.; Roussel, A. M. Tea increases insulin sensitivity and decreases oxidative stress in rats with metabolic syndrome (abstract). Proceedings of the 18th International Congress of Nutrition, 19-23 September 2005, Durban, South Africa; p 1.3.1.
31. Dawson, H. D.; Beshah, E.; Nishi, S.; Solano-Aguilar, G.; Morimoto, M.; Zhao, A.; Madden, K. B.; Ledbetter, T. K.; Dubey, J. P.; Shea-Donohue, T.; Lunney, J. K.; Urban, J. F., Jr. Localized multigene expression patterns support an evolving Th1/Th2-like paradigm in response to infections with Toxoplasma gondii and Ascaris suum. Infect. Immun. 2005, 73, 1116-1128.
32. Livak, K. J.; Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001, 25, 402-408.
33. Khan, A.; Safdar, M.; li Khan, M. M.; Khattak, K. N.; Anderson, R. A. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003, 26, 3215-3218.
34. Anderson, R. A.; Broadhurst, C. L.; Polansky, M. M.; Schmidt, W. F.; Khan, A.; Flanagan, V. P. Schoene, N. W.; Graves, D. J. Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity. J. Agric. Food Chem. 2004, 52, 65-70.
35. Jarvill-Taylor, K. J.; Anderson, R. A.; Graves, D. J. A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J. Am. Coll Nutr. 2001, 20, 327-336.
36. Imparl-Radosevich, J.; Deas, S.; Polansky, M. M.; Baedke, D. A.; Ingebritsen, T. S.; Anderson, R. A.; Graves, D. J. Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: Implications for cinnamon regulation of insulin signalling. Horm. Res. 1998, 50, 177-182.
37. Qin, B.; Nagasaki, M.; Ren, M.; Bajotto, G.; Oshtda, Y.; Sato, Y. Cinnamon extract (traditional herb) potentiates in vivo insulin-regulated glucose utilization via enhancing insulin signaling in rats. Diabetes Res. Clin. Pract. 2003, 62, 139-148.
38. Anton, S.; Melville, L.; Rena, G. Epigallocatechin gallate (EGCG) mimics insulin action on the transcription factor FOXOIa and elicits cellular responses in the presence and absence of insulin. Cell Signal. 2007, 19, 378-383.
39. Li, R. W.; Douglas, T. D.; Maiyoh, G. K.; Adeli, K.; Theriault, A. G. Green tea leaf extract improves lipid and glucose homeostasis in a fructose-fed insulin-resistant hamster model. J. Ethnopharmacol. 2006, 104, 24-31.
40. Garvey, W. T.; Maianu, L.; Huecksteadt, T. P.; Birnbaum, M. J.; Molina, J. M.; Ciaraldi, T. P. Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity. J. Clin. Invest. 1991, 87, 1072-1081.
41. Valverde, A. M.; Navarro, P.; Teruel, T.; Conejo, R.; Benito, M.; Lorenzo, M. Insulin and insulin-like growth factor I up-regulate GLUT4 gene expression in fetal brown adipocytes, in a phosphoinositide 3-kinase-dependent manner. Biochem. J. 1999, 337, 397-405.
42. Hernandez, R.; Teruel, T.; Lorenzo, M. Insulin and dexamethasone induce GLUT4 gene expression in foetal brown adipocytes: Synergistic effect through CCAAT/enhancer-binding protein alpha. Biochem. J. 2003, 372, 617-624.
43. Yu, Z. W.; Buren, J.; Enerback, S.; Nilsson, E.; Samuelsson, L.; Eriksson, J. W. Insulin can enhance GLUT4 gene expression in 3T3-F442A cells and this effect is mimicked by vanadate but counteracted by cAMP and high glucose - Potential implications for insulin resistance. Biochim. Biophys. Acta 2001, 1535, 174-185.
44. Frame, S.; Cohen, P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 2001, 359, 1-16.
45. Cao, H. Expression, purification, and biochemical characterization of the antiinflammatory tristetraprolin: A zinc-dependent mRNA binding protein affected by posttranslational modifications. Biochemistry 2004, 43, 13724-13738.
46. Carballo, E.; Cao, H.; Lai, W. S.; Kennington, E. A.; Campbell, D.; Blackshear, P. J. Decreased sensitivity of tristetraprolin-deficient cells to p38 inhibitors suggests the involvement of tristetraprolin in the p38 signaling pathway. J. Biol. Chem. 2001, 276, 42580-42587.
47. Cao, H.; Deterding, L. J.; Venable, J. D.; Kennington, E. A.; Yates, J. R., III; Tomer, K. B.; Blackshear, P. J. Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. Biochem. J. 2006, 394, 285-297.
48. Blackshear, P. J. Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover. Biochem. Soc. Trans. 2002, 30, 945-952.
49. Anderson, P.; Phillips, K.; Stoecklin, G.; Kedersha, N. Post-transcriptional regulation of proinflammatory proteins. J. Leukocyte Biol. 2004, 76, 42-47.
50. Carballo, E.; Lai, W. S.; Blackshear, P. J. Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin. Science 1998, 281, 1001-1005.
51. Carballo, E.; Lai, W. S.; Blackshear, P. J. Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA dead-enylation and stability. Blood 2000, 95, 1891-1899.
52. Kim, W.; Khil, L. Y.; Clark, R.; Bok, S. H.; Kim, E. E.; Lee, S.; Jun, H. S.; Yoon, J. W. Naphthalenemethyl ester derivative of dihydroxyhydrocinnamic acid, a component of cinnamon, increases glucose disposal by enhancing translocation of glucose transporter 4. Diabetologia 2006, 49, 2437-2448.