Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2

Biochemistry

Volumn 46, Issue 30, 2007, Pages 8725-8733

  Zhao, Bin ^a   Lamb, David C ^b   Lei, Li ^a   Kelly, Steven L ^b   Yuan, Hang ^a   Hachey, David L ^a   Waterman, Michael R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING MODES; CONJUGATED PIGMENTS; DELETERIOUS EFFECTS; FLAVIOLIN SUBSTRATES;

BINDING ENERGY; CATALYST ACTIVITY; MOLAR MASS; PIGMENTS; SUBSTRATES; X RAY CRYSTALLOGRAPHY;

PROTEINS;

CYTOCHROME P450 158A1; CYTOCHROME P450 158A2; CYTOCHROME P450 ISOENZYME; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE STUDY; DIMERIZATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; STEREOSPECIFICITY; STREPTOMYCES COELICOLOR; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; BINDING SITES; CARBON-CARBON DOUBLE BOND ISOMERASES; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; DIMERIZATION; MODELS, MOLECULAR; NAPHTHOQUINONES; OXIDATION-REDUCTION; PIGMENTS, BIOLOGICAL; PROTEIN CONFORMATION; STREPTOMYCES COELICOLOR; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); STREPTOMYCES COELICOLOR;

EID: 34547634418     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7006959     Document Type: Article

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