Trithiocarbonates-Exploration of a new head group for HDAC inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 17, 2007, Pages 4746-4752

  Dehmel, Florian ^a   Ciossek, Thomas ^a   Maier, Thomas ^a   Weinbrenner, Steffen ^a   Schmidt, Beate ^a   Zoche, Martin ^a   Beckers, Thomas ^a  

^a ALTANA PHARMA AG   (Germany)

Author keywords

HDAC inhibitors; Histone deacetylase; Novel head group; Trithiocarbonates

Indexed keywords

FR 901228; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; TRITHIOCARBONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; VORINOSTAT;

ARTICLE; CUTANEOUS T CELL LYMPHOMA; DRUG ACTIVITY; DRUG POTENCY; ENZYME INHIBITION; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

CARBON; CARBONATES; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; ENZYME INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; INHIBITORY CONCENTRATION 50; LYMPHOMA, T-CELL; MODELS, CHEMICAL; MOLECULAR CONFORMATION; SKIN NEOPLASMS; ZINC;

EID: 34547549500     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.06.063     Document Type: Article

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