Molecular docking and spatial coarse graining simulations as tools to investigate substrate recognition, enhancer binding and conformational transitions in indoleamine-2,3-dioxygenase (IDO)

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1774, Issue 8, 2007, Pages 1058-1068

  Macchiarulo, Antonio ^a   Nuti, Roberto ^a   Bellocchi, Daniele ^a   Camaioni, Emidio ^a   Pellicciari, Roberto ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Docking; Enhancer; IDO; Spatial coarse graining simulation; Substrate recognition

Indexed keywords

INDOLEAMINE 2,3 DIOXYGENASE;

ARTICLE; CONFORMATIONAL TRANSITION; ELECTRICITY; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE; MOLECULAR DOCKING; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN MOTIF; SIMULATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID MOTIFS; ANIMALS; CATALYTIC DOMAIN; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; KYNURENINE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; SOFTWARE; SUBSTRATE SPECIFICITY; TRYPTOPHAN;

EID: 34547435173     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2007.06.007     Document Type: Article

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