Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 22, 2007, Pages 9393-9398

  Piaggio, Eliane ^a,b   Mars, Lennart T ^a,b   Cassan, Cécile ^a,b   Cabarrocas, Julie ^a,b   Hofstätter, Maria ^c   Desbois, Sabine ^a,b   Bergereau, Emilie ^a,b   Rötzschke, Olaf ^c   Falk, Kirsten ^c   Liblau, Roland S ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Autoimmunity immune tolerance; Foxp3; Immunotherapy; Regulatory T cells

Indexed keywords

EPITOPE; HEMAGGLUTININ; HEMAGGLUTININ[107-119]; INSULIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; COVALENT BOND; DIABETES MELLITUS; DRUG EFFICACY; HELPER CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOTHERAPY; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; ANIMAL; CELL LINE; CHEMISTRY; DISEASE MODEL; DRUG EFFECT; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; PATHOLOGY; SENSITIVITY AND SPECIFICITY; TRANSGENIC MOUSE;

MUS; RATTUS;

ANIMALS; CELL LINE; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; EPITOPES, T-LYMPHOCYTE; HEMAGGLUTININS; IMMUNE TOLERANCE; MICE; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; SENSITIVITY AND SPECIFICITY; T-LYMPHOCYTES;

EID: 34547223059     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0610423104     Document Type: Article

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