Type II NADH:menaquinone oxidoreductase of Mycobacterium tuberculosis

Infectious Disorders - Drug Targets

Volumn 7, Issue 2, 2007, Pages 169-181

  Teh, J S ^a,b   Yano, T ^c   Rubin, H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Tokyo Institute of Technology ^*  (United States)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Dormancy; Drug; Inhibition; Mycobacteria; NADH; Oxidoreductase; Phenothiazine; Tuberculosis

Indexed keywords

1 (6 BROMO 2 METHOXY 3 QUINOLINYL) 4 DIMETHYLAMINO 2 (1 NAPHTHYL) 1 PHENYL 2 BUTANOL; CHLORPROMAZINE; DESIPRAMINE; ETHIONAMIDE; FUMARATE REDUCTASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE; ISONIAZID; METRONIDAZOLE; NITRATE REDUCTASE; OXOGLUTARATE DEHYDROGENASE; PENICILLIN G; PHENOTHIAZINE DERIVATIVE; PROMAZINE; PROMETHAZINE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PYRAZINAMIDE; PYRUVATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (MENAQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; RIFABUTIN; RIFAMPICIN; ROTENONE; STREPTOMYCIN; THIORIDAZINE; TRIFLUOPERAZINE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIAL GENOME; BACTERIAL METABOLISM; BACTERIAL STRAIN; BACTERIAL SURVIVAL; DRUG EFFICACY; DRUG POTENCY; DRUG POTENTIATION; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IC 50; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATIVE STRESS; PATIENT COMPLIANCE; RESPIRATORY CHAIN; REVIEW; SURVIVAL TIME; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; DRUG RESISTANCE, BACTERIAL; ELECTRON TRANSPORT; ENZYME INHIBITORS; ETHIONAMIDE; ISONIAZID; MYCOBACTERIUM TUBERCULOSIS; PHENOTHIAZINES; QUINONE REDUCTASES;

EID: 34547127139     PISSN: 18715265     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152607781001781     Document Type: Review

References (93)

1. Gandhi, N.R.; Moll, A.; Sturm, A.W.; Pawinski, R.; Govender, T.; Lalloo, U.; Zeller, K.; Andrews, J.; Friedland, G. Lancet, 2006, 368, 1575.
2. Kristiansen, J. E.; Vergmann, B. APMIS, 1986, 94, 393.
3. Molnar, J.; Beladi, I.; Foldes, I., Zentbl. Bakteriol. Parasitenkd. Infektkrankh. Hyg. Abt., 1977, 239, 521.
4. Weinstein E.A.; Yano, T.; Li, L.S.; Avarbock, D.; Avarbock, A.; Helm, D.; McColm, A.A.; Duncan, K.; Lonsdale, J.T.; Rubin, H. Proc. Natl. Acad. Sci U. S. A., 2005, 102, 4548.
5. Aziz, M.A.; Wright, A.; Laszlo, A.; De Muynck, A.; Portaels, F.; Van Deun, A.; Wells, C.; Nunn, P.; Blanc, L.; Raviglione, M.; WHO/IUATLD. Lancet, 2006, 368, 2142.
6. Centers for Disease Control and Prevention (CDC). MMWR Morb. Mortal. Wkly. Rep., 2006, 55, 301.
7. Centers for Disease Control and Prevention (CDC). MMWR. Morb. Mortal. Wkly. Rep., 2007, 56, 250.
8. Cole, S.T.; Brosch, R.; Parkhill, J.; Garnier, T.; Churcher, C.; Harris, D.; Gordon, S.V.; Eiglmeier, K.; Gas, S.; Barry, C.E. 3rd. Tekaia, F.; Badcock, K.; Basham, D.; Brown, D.; Chillingworth, T.; Connor, R.; Davies, R.; Devlin, K.; Feltwell, T.; Gentles, S.; Hamlin, N.; Holroyd, S.; Hornsby, T.; Jagels, K.; Krogh, A.; McLean, J.; Moule, S.; Murphy, L.; Oliver, K.; Osborne, J.; Quail, M.A.; Rajandream, M.A.; Rogers, J.; Rutter, S.; Seeger, K.; Skelton, J.; Squares, R.; Squares, S.; Sulston, J.E.; Taylor, K.; Whitehead, S.; Barrell, B.G. Nature, 1998, 393, 537.
9. Melo, A.M.; Bandeiras, T.M.; Teixeira, M. Microbiol. Mol. Biol. Rev., 2004, 68, 603.
10. Pereira, M.M.; Santana, M.; Teixeira, M. Biochim. Biophys. Acta., 2001, 1505, 185.
11. Cypionka, H. Annu. Rev. Microbiol., 2000, 54, 827.
12. Stenmark, P.; Nordlund, P. FEBS Lett., 2003, 552, 189.
13. Kana, B.D.; Weinstein, E.A.; Avarbock, D.; Dawes, S.S.; Rubin, H.; Mizrahi, V. J. Bacteriol., 2001, 183, 7076.
14. Matsoso, L.G.; Kana, B.D.; Crellin, P.K.; Lea-Smith, D.J.; Pelosi, A.; Powell, D.; Dawes, S.S.; Rubin, H.; Coppel, R.L.; Mizrahi, V. J. Bacteriol., 2005, 187, 6300.
15. Ferguson-Miller, S.; Babcock, G.T. Chem. Rev., 1996, 96, 2889.
16. Sone, N.; Nagata, K.; Kojima, H.; Tajima, J.; Kodera, Y.; Kanamaru, T.; Noguchi, S.; Sakamoto, J., Biochim. Biophys. Acta., 2001, 1503, 279.
17. Sassetti, C.M.; Boyd, D.H.; Rubin, E.J. Mol. Microbiol., 2003, 48, 77.
18. Collins, M.D.; Shah, H.N.; Minnikin, D.E. J. Appl. Bacteriol., 1980, 48, 277.
19. Jones, C.W.; Poole, R.K. Method Microbiol., 1985, 18, 285.
20. Lorence, R.M.; Koland, J.G.; Gennis, R.B. Biochemistry, 1986, 25, 2314.
21. Winstedt, L.; Yoshida, K.; Fujita, Y.; von Wachenfeldt, C. J. Bacteriol., 1998, 180, 6571.
22. Shi, L.; Sohaskey, C.D.; Kana, B.D.; Dawes, S.; North, R.J.; Mizrahi, V.; Gennaro, M.L. Proc. Natl. Acad. Sci. USA, 2005, 102, 15629.
23. Sohaskey, C.D.; Wayne, L.G. J. Bacteriol., 2003, 185, 7247.
24. Aly, S.; Wagner, K.; Keller, C.; Malm, S.; Malzan, A.; Brandau, S.; Bange, F.C.; Ehlers, S. J. Pathol., 2006, 210, 298.
25. Tsai, M.C.; Chakravarty, S.; Zhu, G.; Xu, J.; Tanaka, K.; Koch, C.; Tufariello, J.; Flynn, J.; Chan, J. Cell Microbiol., 2006, 2, 218
26. Botha, T.; Ryffel, B. Immunology, 2002, 107, 350.
27. Flynn, J.L.; Scanga, C.A.; Tanaka, K.E.; Chan, J. J. Immunol., 1998, 160, 1796.
28. Chan, J.; Tanaka, K.; Carroll, D.; Flynn, J.; Bloom, B.R. Infect. Immun., 1995, 63, 736.
29. Choi, H.S.; Rai, P.R.; Chu, H.W.; Cool, C.; Chan, E.D. Am. J. Respir. Crit. Care Med., 2002, 166, 178.
30. Brown, G.C.; Borutaite, V. Biochem. Soc. Symp., 1999, 66, 17.
31. Garland, P.B.; Downie, J.A.; Haddock, B.A. Biochem. J., 1975, 152, 547.
32. McKinney, J.D.; Honer zu Bentrup, K.; Munoz-Elias, E.J.; Miczak, A.; Chen, B.; Chan, W.T.; Swenson, D.; Sacchettini, J.C.; Jacobs, W.R. Jr,; Russell, D.G. Nature, 2000, 406, 735.
33. Boshoff, H.I.; Barry, C.E.3rd. Nat. Rev. Microbiol., 2005, 3, 70.
34. Wayne, L.G.; Sramek, H.A. Antimicrob. Agents Chemother., 1994, 38, 2054.
35. Betts, J.C.; Lukey, P.T.; Robb, L.C.; McAdam, R.A.; Duncan, K. Mol. Microbiol., 2002, 43, 717.
36. Dahl, J.L.; Kraus, C.N.; Boshoff, H.I.; Doan, B.; Foley, K.; Avarbock, D.; Kaplan, G.; Mizrahi, V.; Rubin, H.; Barry, C.E.3rd. Proc. Natl. Acad. Sci. U. S. A., 2003, 100, 10026.
37. Schnappinger, D.; Ehrt, S.; Voskuil, M.I.; Liu, Y.; Mangan, J.A.; Monahan, I.M.; Dolganov, G.; Efron, B.; Butcher, P.D.; Nathan, C.; Schoolnik, G.K. J. Exp. Med., 2003, 198, 693.
38. Wayne, L.G.; Sohaskey, C.D. Annu. Rev. Microbiol., 2001, 55, 139.
39. Sherman, D.R.; Voskuil, M.; Schnappinger, D.; Liao, R.; Harrell, M.I.; Schoolnik, G.K. Proc. Natl. Acad. Sci. U. S. A., 2001, 98, 7534.
40. Wisedchaisri, G.; Wu, M.; Rice, A.E.; Roberts, D.M.; Sherman, D.R.; Hol, W.G. J. Mol. Biol., 2005, 354, 630.
41. Reed, M.B.; Gagneux, S.; Deriemer, K.; Small, P.M.; Barry, C.E. 3rd. J. Bacteriol., 2007, [Epub ahead of print].
42. Park, H.D.; Guinn, K.M.; Harrell, M.I.; Liao, R.; Voskuil, M.I.; Tompa, M.; Schoolnik, G.K.; Sherman, D.R. Mol. Microbiol., 2003, 48, 833.
43. Kendall, S.L.; Movahedzadeh, F.; Rison, S.C.; Wernisch, L.; Parish, T.; Duncan, K.; Betts, J.C.; Stoker, N.G. Tuberculosis, 2004, 84, 247.
44. Yuan, Y.; Crane, D.D.; Simpson, R.M.; Zhu, Y.Q.; Hickey, M.J.; Sherman, D.R.; Barry, C.E. 3rd. Proc. Natl. Acad. Sci. U S. A., 1998, 95, 9578.
45. Yuan, Y.; Crane, D.D.; Barry, C.E. 3rd. J. Bacteriol., 1996, 178, 4484.
46. Bagchi, G.; Chauhan, S.; Sharma, D.; Tyagi, J.S. Microbiology, 2005, 151, 4045.
47. Voskuil, M.I.; Schnappinger, D.; Visconti, K.C.; Harrell, M.I.; Dolganov, G.M.; Sherman, D.R.; Schoolnik, G.K. J. Exp. Med., 2003, 198, 705.
48. Boon, C.; Dick, T. J. Bacteriol., 2002, 184, 6760.
49. Roberts, D.M.; Liao, R.P.; Wisedchaisri, G.; Hol, W.G.; Sherman, D.R. J. Biol. Chem., 2004, 279, 23082.
50. Gilles-Gonzalez, M.A.; Ditta, G.S.; Helinski, D.R. Nature, 1991, 350, 170.
51. Georgellis, D.; Kwon, O.; Lin, E.C. Science, 2001, 292, 2314.
52. JONES, M.G.; Bickar, D.; Wilson, M.T.; Brunori, M.; Colosimo, A.;Sarti, P. Biochem. J., 1984, 220, 57.
53. Wilson, M.T.; Antonini, G.; Malatesta, F.; Sarti, P.; Brunori, M. J. Biol. Chem., 1994, 269, 24114.
54. Antunes, F.; Boveris, A.; Cadenas, E. Proc. Natl. Acad. Sci. U S. A., 2004, 101, 16774.
55. O'Toole, R.; Smeulders, M.J.; Blokpoel, M.C.; Kay, E.J.; Lougheed, K.; Williams, H.D. J. Bacteriol., 2003, 185, 1543.
56. McAdam, R.A.; Quan, S.; Smith, D.A.; Bardarov, S.; Betts, J.C.; Cook, F.C.; Hooker, E.U.; Lewis, A.P.; Woollard, P.; Everett, M.J.; Lukey, P.T.; Bancroft G.J.; Jacobs, W.R. Jr.; Duncan, K. Microbiology, 2002, 148, 2975.
57. Miesel, L.; Weisbrod, T.R.; Marcinkeviciene, J.A.; Bittman, R.; Jacobs, W.R. Jr. J. Bacteriol., 1998, 180, 2459.
58. Pereira, M.M.; Bandeiras, T.M.; Fernandes, A.S.; Lemos, R.S.; Melo, A.M.; Teixeira, M. J. Bioenerg. Biomembr., 2004, 36, 93.
59. Yano, T.; Li, L.S.; Weinstein, E.; Teh, J.S.; Rubin, H. J. Biol. Chem., 2006, 281, 11456.
60. Bjorklof, K.; Zickermann, V.; Finel, M. FEBS Lett., 2000, 467, 105.
61. Jaworowski, A.; Mayo, G.; Shaw, D.C.; Campbell, H.D.; Young, I.G. Biochemistry, 1981, 20, 3621.
62. Nantapong, N.; Otofuji, A.; Migita, C.T.; Adachi, O.; Toyama, H.; Matsushita, K. Biosci. Biotechnol. Biochem., 2005, 69, 149.
63. Brito, J.A.; Bandeiras, T.M.; Teixeira, M.; Vonrhein, C.; Archer, M. Biochim. Biophys. Acta., 2006, 1764, 842.
64. Cohn, D.L.; Bustreo, F.; Raviglione, M.C. Clin. Infect. Dis., 1997, 24, S121.
65. Vilcheze, C.; Weisbrod, T.R.; Chen, B.; Kremer, L.; Hazbon, M.H.; Wang, F.; Alland, D.; Sacchettini, J.C.; Jacobs, W.R., Jr. Antimicrob. Agents Chemother., 2005, 49, 708.
66. Lee, A.S.; Teo, A.S.; Wong, S.Y. Antimicrob. Agents Chemother., 2001, 45, 2157.
67. Hazbon, M.H.; Brimacombe, M.; Bobadilla del Valle, M.; Cavatore, M.; Guerrero, M.I.; Varma-Basil, M.; Billman-Jacobe, H.; Lavender, C.; Fyfe, J.; Garcia-Garcia, L.; Leon, C.I.; Bose, M.; Chaves, F.; Murray, M.; Eisenach, K.D.; Sifuentes-Osornio, J.; Cave, M.D.; Ponce de Leon, A.; Alland, D. Antimicrob. Agents Chemother., 2006, 50, 2640.
68. Zhang, Y.; Heym, B.; Allen, B.; Young, D.; Cole, S. Nature, 1992, 358, 591.
69. Leonardo, M.R.; Dailly, Y.; Clark, D.P. J. Bacteriol., 1996, 178, 6013.
70. Harrison, D.E.; Chance, B. Appl. Microbiol., 1970, 19, 446.
71. Guo, H.; Seet, Q.; Denkin, S.; Parsons, L.; Zhang, Y. J. Med. Microbiol., 2006, 55, 1527.
72. Ramaswamy, S.V.; Reich, R.; Dou, S.J.; Jasperse, L.; Pan, X.; Wanger, A.; Quitugua, T.; Graviss,.E.A. Antimicrob. Agents Chemother., 2003, 47, 1241.
73. Boshoff, H.I.; Myers, T.G.; Copp, B.R.; McNeil, M.R.; Wilson, M.A.; Barry, C.E. 3rd. J. Biol. Chem., 2004, 279, 40174.
74. Cabusora, L.; Sutton, E.; Fulmer, A.; Forst, C.V. Bioinformatics, 2005, 21, 2898.
75. Vilcheze, C.; Wang, F.; Arai, M.; Hazbon, M.H.; Colangeli, R.; Kremer, L.; Weisbrod, T.R.; Alland, D.; Sacchettini, J.C.; Jacobs, W.R. Jr. Nat. Med., 2006, 12, 1027.
76. Cardoso, R.F.; Cardoso, M.A.; Leite, C.Q.; Sato, D.N.; Mamizuka, E.M.; Hirata, R.D.; Mello, F.F.; Hirata, M.H. Mem. Inst. Oswaldo Cruz., 2007, 102, 59.
77. Pleasure, H. Psychiatr. Q., 1956, 30, 23.
78. Fisher, R.A.; Teller, E. Dis. Chest, 1959, 35, 134.
79. Ratnakar, P.; Murthy, P.S. FEMS Microbiol. Lett., 1992, 76, 73.
80. Amaral, L.; Kristiansen, J.E.; Abebe, L.S.; Millett, W. J. Antimicrob. Chemother., 2001, 47, 505.
81. Gadre, D.V.; Talwar, V.; Gupta, H. C.; Murthy, P.S. Int. Clin. Psychopharmacol., 1998, 13, 129.
82. Ordway, D.; Viveiros, M.; Leandro, C.; Bettencourt, R.; Almeida, J.; Martins, M.; Kristiansen, J.E.; Molnar, J.; Amaral, L. Antimicrob. Agents Chemother., 2003, 47, 917.
83. Bettencourt, M.V.; Bosne-David, S.; Amaral, L. Int. J. Antimicrob. Agents., 2000, 16, 69.
84. Amaral, L.; Kristiansen, J.E.; Abebe, L.S.; Millett, W. J. Antimicrob. Chemother., 1996, 38, 1049.
85. Crowle, A.J.; Douvas, G.S.; May, M.H. Chemotherapy, 1992, 38, 410.
86. Reddy, M. V.; Nadadhur, G.; Gangadharam, P.R.J. J. Antimicrob. Chemother., 1996, 37, 196.
87. Katoch, V.M.; Saxena, N.; Shivannavar, C.T.; Sharma, V.D.; Katoch, K.; Sharma, R.K.; Murthy, P.S. FEMS Immunol. Med. Microbiol., 1998, 20, 99.
88. British Thoracic Society. Br. J. Dis. Chest., 1984, 78, 330.
89. Zhang, Y.; Wade, M.M.; Scorpio, A.; Zhang, H.; Sun, Z. J. Antimicrob. Chemother., 2003, 52, 790.
90. Xie, Z.; Siddiqi, N.; Rubin, E.J. Antimicrob. Agents Chemother., 2005, 49, 4778.
91. Wu, M.; Xu, L.G.; Li, X.; Zhai, Z.; Shu, H.B. J. Biol. Chem., 2002, 277, 25617.
92. Wu, M.; Xu, L.G.; Su, T.; Tian, Y.; Zhai, Z.; Shu, H.B. Oncogene, 2004, 23, 6815.
93. Andries, K.; Verhasselt, P.; Guillemont, J.; Gohlmann, H.W.; Neefs, J.M.; Winkler, H.; Van Gestel, J.; Timmerman, P.; Zhu, M.; Lee, E.; Williams, P.; de Chaffoy, D.; Huitric, E.; Hoffner, S.; Cambau, E.; Truffot-Pernot, C.; Lounis, N.; Jarlier, V. Science, 2005, 307, 223.