Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia

Journal of Biological Chemistry

Volumn 282, Issue 27, 2007, Pages 19762-19772

  Rydziel, Sheila ^a   Stadmeyer, Lisa ^a   Zanotti, Stefano ^a   Durant, Deena ^a   Smerdel Ramoya, Anna ^a   Canalis, Ernesto ^a,b  

^a SAINT FRANCIS HOSPITAL AND MEDICAL CENTER   (United States)

^b UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; ENZYME ACTIVITY; ENZYME INHIBITION; OSTEOBLASTS; TISSUE;

HUMAN OSTEOCALCIN PROMOTERS; OSTEOBLASTIC CELLS; OSTEOBLASTOGENESIS; OSTEOPENIA;

PROTEINS;

ALKALINE PHOSPHATASE; BETA CATENIN; BONE MORPHOGENETIC PROTEIN 2; CONNECTIVE TISSUE GROWTH FACTOR; GLUTATHIONE TRANSFERASE; MESSENGER RNA; NOTCH RECEPTOR; OSTEOCALCIN; RETROVIRUS VECTOR; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BONE DEVELOPMENT; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOPLASM; ENZYME ACTIVITY; FEMALE; GENE OVEREXPRESSION; LYMPHOCYTE TRANSFORMATION; MALE; MOUSE; NEPHROBLASTOMA; NONHUMAN; OSTEOPENIA; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STROMA; TRANSGENIC MOUSE;

ALKALINE PHOSPHATASE; ANIMALS; BONE DISEASES, METABOLIC; BONE MORPHOGENETIC PROTEINS; CELL LINE; FEMALE; GENE EXPRESSION; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, TRANSGENIC; OSTEOCALCIN; OSTEOGENESIS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEINS;

CYTOMEGALOVIRUS; MURINAE; MUS MUSCULUS;

EID: 34547104029     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700212200     Document Type: Article

References (70)

1. Bianco, P., and Gehron, R. P. (2000) J. Clin. Investig. 105, 1663-1668
2. Canalis, E., Economides, A. N., and Gazzerro, E. (2003) Endocr. Rev. 24, 218-235
3. Thies, R. S., Bauduy, M., Ashton, B. A., Kurtzberg, L., Wozney, J. M., and Rosen, V. (1992) Endocrinology 130, 1318-1324
4. Ghosh-Choudhury, N., Harris, M. A., Feng, J. Q., Mundy, G. R., and Harris, S. E. (1994) Crit. Rev. Eukaryot. Gene Expr. 4, 345-355
5. Miyazono, K. (1999) Bone 25, 91-93
6. Nohe, A., Keating, E., Knaus, P., and Petersen, N. O. (2004) Cell. Signal. 16, 291-299
7. Nohe, A., Hassel, S., Ehrlich, M., Neubauer, F., Sebald, W., Henis, Y. I., and Knaus, P. (2002) J. Biol. Chem. 277, 5330-5338
8. Lai, C. F., and Cheng, S. L. (2002) J. Biol. Chem. 277, 15514-15522
9. Krishnan, V., Bryant, H. U., and MacDougald, O. A. (2006) J. Clin. Investig. 116, 1202-1209
10. Westendorf, J. J., Kahler, R. A., and Schroeder, T. M. (2004) Gene (Amst.) 341, 19-39
11. Wodarz, A., and Nusse, R. (1998) Annu. Rev. Cell Dev. Biol. 14, 59-88
12. Yanagita, M. (2005) Cytokine Growth Factor Rev. 16, 309-317
13. Winkler, D. G., Sutherland, M. S., Ojala, E., Turcott, E., Geoghegan, J. C., Shpektor, D., Skonier, J. E., Yu, C., and Latham, J. A. (2005) J. Biol. Chem. 280, 2498-2502
14. Li, X., Zhang, Y., Kang, H., Liu, W., Liu, P., Zhang, J., Harris, S. E., and Wu, D. (2005) J. Biol. Chem. 280, 19883-19887
15. Laurikkala, J., Kassai, Y., Pakkasjarvi, L., Thesleff, I., and Itoh, N. (2003) Dev. Biol. 264, 91-105
16. Morvan, F., Boulukos, K., Clement-Lacroix, P., Roman, R. S., Suc-Royer, I., Vayssiere, B., Ammann, P., Martin, P., Pinho, S., Pognonec, P., Mollat, P., Niehrs, C., Baron, R., and Rawadi, G. (2006) J. Bone Miner. Res. 21, 934-945
17. Brigstock, D. R. (2003) J. Endocrinol. 178, 169-175
18. Brigstock, D. R., Goldschmeding, R., Katsube, K. I., Lam, S. C., Lau, L. F., Lyons, K., Naus, C., Perbal, B., Riser, B., Takigawa, M., and Yeger, H. (2003) Mol. Pathol. 56, 127-128
19. Garcia, A. J., Coffinier, C., Larrain, J., Oelgeschlager, M., and De Robertis, E. M. (2002) Gene (Amst.) 287, 39-47
20. Abreu, J. G., Ketpura, N. I., Reversade, B., and De Robertis, E. M. (2002) Nat. Cell Biol. 4, 599-604
21. Mercurio, S., Latinkic, B., Itasaki, N., Krumlauf, R., and Smith, J. C. (2004) Development 131, 2137-2147
22. Latinkic, B. V., Mercurio, S., Bennett, B., Hirst, E. M., Xu, Q., Lau, L. F., Mohun, T. J., and Smith, J. C. (2003) Development 130, 2429-2441
23. Joliot, V., Martinerie, C., Dambrine, G., Plassiart, G., Brisac, M., Crochet, J., and Perbal, B. (1992) Mol. Cell. Biol. 12, 10-21
24. Lafont, J., Jacques, C., Dreau, G. L., Calhabeu, F., Thibout, H., Dubois, C., Berenbaum, F., Laurent, M., and Martinerie, C. (2005) J. Bone Miner. Res. 20, 2213-2223
25. Sakamoto, K., Yamaguchi, S., Ando, R., Miyawaki, A., Kabasawa, Y., Takagi, M., Li, C. L., Perbal, B., and Katsube, K. (2002) J. Biol. Chem. 277, 29399-29405
26. Lin, C. G., Chen, C. C., Leu, S. J., Grzeszkiewicz, T. M., and Lau, L. F. (2005) J. Biol. Chem. 280, 8229-8237
27. Gellhaus, A., Dong, X., Propson, S., Maass, K., Klein-Hitpass, L., Kibschull, M., Traub, O., Willecke, K., Perbal, B., Lye, S. J., and Winterhager, E. (2004) J. Biol. Chem. 279, 36931-36942
28. Lecanda, F., Warlow, P. M., Sheikh, S., Furlan, F., Steinberg, T. H., and Civitelli, R. (2000) J. Cell Biol. 151, 931-944
29. Sciaudone, M., Gazzerro, E., Priest, L., Delany, A. M., and Canalis, E. (2003) Endocrinology 144, 5631-5639
30. Dahl, L. K. (1952) Proc. Soc. Exp. Biol. Med. 80, 474-479
31. Nazarenko, I., Lowe, B., Darfler, M., Ikonomi, P., Schuster, D., and Rashtchian, A. (2002) Nucleic Acids Res. 30, e37
32. Nazarenko, I., Pires, R., Lowe, B., Obaidy, M., and Rashtchian, A. (2002) Nucleic Acids Res. 30, 2089-2195
33. Lian, J., Stewart, C., Puchacz, E., Mackowiak, S., Shalhoub, V., Collart, D., Zambetti, G., and Stein, G. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 1143-1147
34. Tso, J. Y., Sun, X. H., Kao, T. H., Reece, K. S., and Wu, R. (1985) Nucleic Acids Res. 13, 2485-2502
35. Laemmli, U. K. (1970) Nature 227, 680-685
36. Su, B. Y., Cai, W. Q., Zhang, C. G., Martinez, V., Lombet, A., and Perbal, B. (2001) Mol. Pathol. 54, 184-191
37. Schreiber, E., Matthias, P., Muller, M. M., and Schaffner, W. (1989) Nucleic Acids Res. 17, 6419
38. Gazzerro, E., Pereira, R. C., Jorgetti, V., Olson, S., Economides, A. N., and Canalis, E. (2005) Endocrinology 146, 655-665
39. Persson, U., Izumi, H., Souchelnytskyi, S., Itoh, S., Grimsby, S., Engstrom, U., Heldin, C. H., Funa, K., and ten Dijke, P. (1998) FEBS Lett. 434, 83-87
40. Ishisaki, A., Yamato, K., Hashimoto, S., Nakao, A., Tamaki, K., Nonaka, K., ten Dijke, P., Sugino, H., and Nishihara, T. (1999) J. Biol. Chem. 274, 13637-13642
41. Deregowski, V., Gazzerro, E., Priest, L., Rydziel, S., and Canalis, E. (2006) J. Biol. Chem. 281, 6203-6210
42. Young, C. S., Kitamura, M., Hardy, S., and Kitajewski, J. (1998) Mol. Cell. Biol. 18, 2474-2485
43. Zhao, M., Qiao, M., Harris, S. E., Oyajobi, B. O., Mundy, G. R., and Chen, D. (2004) J. Biol. Chem. 279, 12854-12859
44. Zawel, L., Dai, J. L., Buckhaults, P., Zhou, S., Kinzler, K. W., Vogelstein, B., and Kern, S. E. (1998) Mol. Cell 1, 611-617
45. Billiard, J., Way, D. S., Seestaller-Wehr, L. M., Moran, R. A., Mangine, A., and Bodine, P. V. (2005) Mol. Endocrinol. 19, 90-101
46. Nam, Y., Sliz, P., Song, L., Aster, J. C., and Blacklow, S. C. (2006) Cell 124, 973-983
47. Wilson, J. J., and Kovall, R. A. (2006) Cell 124, 985-996
48. Strobl, L. J., Hofelmayr, H., Stein, C., Marschall, G., Brielmeier, M., Laux, G., Bornkamm, G. W., and Zimber-Strobl, U. (1997) Immunobiology 198, 299-306
49. Lardelli, M., and Lendahl, U. (1993) Exp. Cell Res. 204, 364-372
50. Hagen, T., Di, D. E., Culbert, A. A., and Reith, A. D. (2002) J. Biol. Chem. 277, 23330-23335
51. Tian, G., Ghanekar, S. V., Aharony, D., Shenvi, A. B., Jacobs, R. T., Liu, X., and Greenberg, B. D. (2003) J. Biol. Chem. 278, 28968-28975
52. Sims, N. A., White, C. P., Sunn, K. L., Thomas, G. P., Drummond, M. L., Morrison, N. A., Eisman, J. A., and Gardiner, E. M. (1997) Mol. Endocrinol. 11, 1695-1708
53. Parfitt, A. M., Drezner, M. K., Glorieux, F. H., Kanis, J. A., Malluche, H., Meunier, P. J., Ott, S. M., and Recker, R. R. (1987) J. Bone Miner. Res. 2, 595-610
54. Kretzschmar, M., Doody, J., and Massague, J. (1997) Nature 389, 618-622
55. Osyczka, A. M., and Leboy, P. S. (2005) Endocrinology 146, 3428-3437
56. May, P., Reddy, Y. K., and Herz, J. (2002) J. Biol. Chem. 277, 18736-18743
57. Gazzerro, E., Rydziel, S., and Canalis, E. (1999) Endocrinology 140, 562-567
58. Harris, S. E., Sabatini, M., Harris, M. A., Feng, J. Q., Wozney, J., and Mundy, G. R. (1994) J. Bone Miner. Res. 9, 389-394
59. Pereira, R. C., Rydziel, S., and Canalis, E. (2000) J. Cell. Physiol. 182, 239-246
60. Frenkel, B., Capparelli, C., Van Auken, M., Baran, D., Bryan, J., Stein, J. L., Stein, G. S., and Lian, J. B. (1997) Endocrinology 138, 2109-2116
61. Parisi, M. S., Gazzerro, E., Rydziel, S., and Canalis, E. (2006) Bone 38, 671-677
62. Liu, Z., Tang, Y., Qiu, T., Cao, X., and Clemens, T. L. (2006) J. Biol. Chem. 281, 17156-17163
63. Gazzerro, E., Deregowski, V., Vaira, S., and Canalis, E. (2005) Endocrinology 146, 3875-3882
64. Ross, J. J., Shimmi, O., Vilmos, P., Petryk, A., Kim, H., Gaudenz, K., Hermanson, S., Ekker, S. C., O'Connor, M. B., and Marsh, J. L. (2001) Nature 410, 479-483
65. Chang, C., Holtzman, D. A., Chau, S., Chickering, T., Woolf, E. A., Holmgren, L. M., Bodorova, J., Gearing, D. P., Holmes, W. E., and Brivanlou, A. H. (2001) Nature 410, 483-487
66. Nosaka, T., Morita, S., Kitamura, H., Nakajima, H., Shibata, F., Morikawa, Y., Kataoka, Y., Ebihara, Y., Kawashima, T., Itoh, T., Ozaki, K., Senba, E., Tsuji, K., Makishima, F., Yoshida, N., and Kitamura, T. (2003) Mol. Cell. Biol. 23, 2969-2980
67. Gazzerro, E., Deregowski, V., Stadmeyer, L., Gale, N. W., Economides, A. N., and Canalis, E. (2006) Bone 39, 1252-1260
68. Si, W., Kang, Q., Luu, H. H., Park, J. K., Luo, Q., Song, W. X., Jiang, W., Luo, X., Li, X., Yin, H., Montag, A. G., Haydon, R. C., and He, T. C. (2006) Mol. Cell. Biol. 26, 2955-2964
69. Calhabeu, F., Lafont, J., Le, D. G., Laurent, M., Kazazian, C., Schaeffer, L., Martinerie, C., and Dubois, C. (2006) Exp. Cell Res. 312, 1876-1889
70. Holmen, S. L., Zylstra, C. R., Mukherjee, A., Sigler, R. E., Faugere, M. C., Bouxsein, M. L., Deng, L., Clemens, T. L., and Williams, B. O. (2005) J. Biol. Chem. 280, 21162-21168