Metabolic and ionic coupling factors in amino acid-stimulated insulin release in pancreatic β-HC9 cells

American Journal of Physiology - Endocrinology and Metabolism

Volumn 292, Issue 6, 2007, Pages

  Doliba, Nicolai M ^a,c   Wehrli, Suzanne L ^b   Vatamaniuk, Marko Z ^a   Qin, Wei ^a   Buettger, Carol W ^a   Collins, Heather W ^a   Matschinsky, Franz M ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Amino acids; Energy metabolism; Mitochondria; Oxygen consumption; Sodium

Indexed keywords

2 AMINO 2 NORBORNANECARBOXYLIC ACID; ADENOSINE DIPHOSPHATE MAGNESIUM; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE MAGNESIUM; AGAROSE; AMINO ACID; ASPARTIC ACID; CREATINE PHOSPHATE; CYCLIC AMP; DIAZOXIDE; GLUCOSE; GLUTAMATE AMMONIA LIGASE; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; GLUTAMINE; INSULIN; ISOBUTYLMETHYLXANTHINE; METHIONINE SULFOXIMINE; NORBORNANE DERIVATIVE; OXYGEN; PHOSPHATE; PHOSPHODIESTERASE INHIBITOR; PHOSPHORUS 31; POTASSIUM CHANNEL; PROTON; SODIUM 23; SODIUM ION; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; COUPLING FACTOR; ENERGY METABOLISM; INSULIN RELEASE; MOUSE STRAIN; OXYGEN CONSUMPTION; PANCREAS ISLET BETA CELL; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RESPIROMETRY;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ANIMALS; CELL LINE; CYCLIC AMP; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; GLUCOSE; GLUTAMINE; HYDROGEN-ION CONCENTRATION; INSULIN; INSULIN-SECRETING CELLS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; OXYGEN CONSUMPTION; PHOSPHATES; PHOSPHORYLATION; POTASSIUM CHANNELS; SODIUM; TIME FACTORS;

EID: 34447569494     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00282.2006     Document Type: Article

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