메뉴 건너뛰기




Volumn 289, Issue 5 52-5, 2005, Pages

Adenine nucleotide regulation in pancreatic β-cells: Modeling of ATP/ADP-Ca2+ interactions

Author keywords

Adenosine triphosphate sensitive potassium channels; Insulin; Islets; Mathematical model; Oscillations

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM CHANNEL; CALCIUM ION; GLUCOSE; INSULIN; POTASSIUM CHANNEL;

EID: 27144441359     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00595.2004     Document Type: Article
Times cited : (58)

References (73)
  • 1
    • 0035864148 scopus 로고    scopus 로고
    • 2+ oscillations and insulin secretion in pancreatic islets
    • 2+ oscillations and insulin secretion in pancreatic islets. Biochem J 353: 175-180, 2001.
    • (2001) Biochem J , vol.353 , pp. 175-180
    • Ainscow, E.K.1    Rutter, G.A.2
  • 3
    • 0033838979 scopus 로고    scopus 로고
    • The β-cell KATP channel
    • Ashcroft SJ. The β-cell KATP channel. J Membrane Biol 176: 187-206, 2000.
    • (2000) J Membrane Biol , vol.176 , pp. 187-206
    • Ashcroft, S.J.1
  • 5
    • 0036311359 scopus 로고    scopus 로고
    • Role of oscillations in membrane potential, cytoplasmic Ca2+, and metabolism for plasma insulin oscillations
    • Bergsten P. Role of oscillations in membrane potential, cytoplasmic Ca2+, and metabolism for plasma insulin oscillations. Diabetes 51: S171-S176, 2002.
    • (2002) Diabetes , vol.51
    • Bergsten, P.1
  • 6
    • 10044256230 scopus 로고    scopus 로고
    • Calcium and glycolysis mediate multiple bursting modes in pancreatic islets
    • Bertram R, Satin L, Zhang M, Smolen P, and Sherman A. Calcium and glycolysis mediate multiple bursting modes in pancreatic islets. Biophys J 87: 3074-3087, 2004.
    • (2004) Biophys J , vol.87 , pp. 3074-3087
    • Bertram, R.1    Satin, L.2    Zhang, M.3    Smolen, P.4    Sherman, A.5
  • 8
    • 77049233362 scopus 로고
    • Respiratory enzymes in oxidative phosphorylation. I. Kinetics of oxygen utilization
    • Chance B and Williams GR. Respiratory enzymes in oxidative phosphorylation. I. Kinetics of oxygen utilization. J Biol Chem 217: 383-393, 1955.
    • (1955) J Biol Chem , vol.217 , pp. 383-393
    • Chance, B.1    Williams, G.R.2
  • 9
    • 0030808053 scopus 로고    scopus 로고
    • Effects of extracellular calcium on electrical bursting and intracellular and luminal calcium oscillations in insulin secreting pancreatic β-cells
    • Chay TR. Effects of extracellular calcium on electrical bursting and intracellular and luminal calcium oscillations in insulin secreting pancreatic β-cells. Biophys J 73: 1673-1688, 1997.
    • (1997) Biophys J , vol.73 , pp. 1673-1688
    • Chay, T.R.1
  • 10
    • 0024994145 scopus 로고
    • The effect of ATP-sensitive K+ channels on the electrical burst activity and insulin secretion in pancreatic beta-cells
    • Chay TR, Kim JR, and Cook DL. The effect of ATP-sensitive K+ channels on the electrical burst activity and insulin secretion in pancreatic beta-cells. Cell Biophys 17: 11-36, 1990.
    • (1990) Cell Biophys , vol.17 , pp. 11-36
    • Chay, T.R.1    Kim, J.R.2    Cook, D.L.3
  • 11
    • 0029997476 scopus 로고    scopus 로고
    • Temporal sequence of metabolic and ionic events in glucose-stimulated clonal pancreatic beta-cells (HIT)
    • Civelek VN, Deeney JT, Kubik K, Schultz V, Tornheim K, and Corkey BE. Temporal sequence of metabolic and ionic events in glucose-stimulated clonal pancreatic beta-cells (HIT). Biochem J 315: 1015-1019, 1996.
    • (1996) Biochem J , vol.315 , pp. 1015-1019
    • Civelek, V.N.1    Deeney, J.T.2    Kubik, K.3    Schultz, V.4    Tornheim, K.5    Corkey, B.E.6
  • 12
    • 0023914251 scopus 로고
    • ATP-sensitive K+ channels in pancreatic beta-cells. Spare-channel hypothesis
    • Cook DL, Satin LS, Ashford ML, and Hales CN. ATP-sensitive K+ channels in pancreatic beta-cells. Spare-channel hypothesis. Diabetes 37: 495-498, 1988.
    • (1988) Diabetes , vol.37 , pp. 495-498
    • Cook, D.L.1    Satin, L.S.2    Ashford, M.L.3    Hales, C.N.4
  • 13
    • 0023025490 scopus 로고
    • Regulation of free and bound magnesium in rat hepatocytes and isolated mitochondria
    • Corkey BE, Duszynski J, Rich TL, Matschinsky B, and Williamson JR. Regulation of free and bound magnesium in rat hepatocytes and isolated mitochondria. J Biol Chem 261: 2567-2574, 1986.
    • (1986) J Biol Chem , vol.261 , pp. 2567-2574
    • Corkey, B.E.1    Duszynski, J.2    Rich, T.L.3    Matschinsky, B.4    Williamson, J.R.5
  • 15
    • 0037380954 scopus 로고    scopus 로고
    • An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics
    • Cortassa S, Aon MA, Marban E, Winslow RL, and O'Rourke B. An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophys J 84: 2734-2755, 2003.
    • (2003) Biophys J , vol.84 , pp. 2734-2755
    • Cortassa, S.1    Aon, M.A.2    Marban, E.3    Winslow, R.L.4    O'Rourke, B.5
  • 16
    • 0032875616 scopus 로고    scopus 로고
    • Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis
    • Davis EA, Cuesta-Munoz A, Raoul M, Buettger C, Sweet I, Moates M, Magnuson MA, and Matschinsky FM. Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis. Diabetologia 42: 1175-1186, 1999.
    • (1999) Diabetologia , vol.42 , pp. 1175-1186
    • Davis, E.A.1    Cuesta-Munoz, A.2    Raoul, M.3    Buettger, C.4    Sweet, I.5    Moates, M.6    Magnuson, M.A.7    Matschinsky, F.M.8
  • 18
    • 0032545293 scopus 로고    scopus 로고
    • The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets
    • Detimary P, Dejonghe S, Ling Z, Pipeleers D, Schuit F, and Henquin JC. The changes in adenine nucleotides measured in glucose-stimulated rodent islets occur in beta cells but not in alpha cells and are also observed in human islets. J Biol Chem 273: 33905-33908, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 33905-33908
    • Detimary, P.1    Dejonghe, S.2    Ling, Z.3    Pipeleers, D.4    Schuit, F.5    Henquin, J.C.6
  • 19
    • 0029833117 scopus 로고    scopus 로고
    • Stable and diffusible pools of nucleotides in pancreatic islet cells
    • Detimary P, Jonas JC, and Henquin JC. Stable and diffusible pools of nucleotides in pancreatic islet cells. Endocrinology 137: 4671-4676, 1996.
    • (1996) Endocrinology , vol.137 , pp. 4671-4676
    • Detimary, P.1    Jonas, J.C.2    Henquin, J.C.3
  • 20
    • 0032528285 scopus 로고    scopus 로고
    • 2+ and the ATP/ADP ratio: A feedback control mechanism in mouse pancreatic islets
    • 2+ and the ATP/ADP ratio: a feedback control mechanism in mouse pancreatic islets. Biochem J 333: 269-274, 1998.
    • (1998) Biochem J , vol.333 , pp. 269-274
    • Detimary, P.1    Gilon, P.2    Henquin, J.C.3
  • 21
    • 0037312854 scopus 로고    scopus 로고
    • Differential effects of glucose and glyburide on energetics and Na+ levels of betaHC9 cells: Nuclear magnetic resonance spectroscopy and respirometry studies
    • Doliba NM, Vatamaniuk MZ, Buettger CW, Qin W, Collins HW, Wehrli SL, Carr RD, and Matschinsky FM. Differential effects of glucose and glyburide on energetics and Na+ levels of betaHC9 cells: nuclear magnetic resonance spectroscopy and respirometry studies. Diabetes 52: 394-402, 2003.
    • (2003) Diabetes , vol.52 , pp. 394-402
    • Doliba, N.M.1    Vatamaniuk, M.Z.2    Buettger, C.W.3    Qin, W.4    Collins, H.W.5    Wehrli, S.L.6    Carr, R.D.7    Matschinsky, F.M.8
  • 23
    • 0033134115 scopus 로고    scopus 로고
    • 2+ in single pancreatic β-cells exposed to tetraethylammonium
    • 2+ in single pancreatic β-cells exposed to tetraethylammonium. Cell Calcium 25: 355-360, 1999.
    • (1999) Cell Calcium , vol.25 , pp. 355-360
    • Eberhardson, M.1    Grapengiesser, E.2
  • 24
    • 0242415358 scopus 로고    scopus 로고
    • Gating mechanism of KATP channels: Function fits form
    • Enkvetchakul D and Nichols CG. Gating mechanism of KATP channels: function fits form. J Gen Physiol 122: 471-480, 2003.
    • (2003) J Gen Physiol , vol.122 , pp. 471-480
    • Enkvetchakul, D.1    Nichols, C.G.2
  • 27
    • 3242789423 scopus 로고    scopus 로고
    • Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells
    • Fridlyand LE and Philipson LH. Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells. Diabetes 53: 1942-1948, 2004.
    • (2004) Diabetes , vol.53 , pp. 1942-1948
    • Fridlyand, L.E.1    Philipson, L.H.2
  • 28
    • 0033050631 scopus 로고    scopus 로고
    • Effect of Na/Ca exchange on plateau fraction and [Ca]i in models for bursting in pancreatic beta-cells
    • Gall D and Susa I. Effect of Na/Ca exchange on plateau fraction and [Ca]i in models for bursting in pancreatic beta-cells. Biophys J 77: 45-53, 1999.
    • (1999) Biophys J , vol.77 , pp. 45-53
    • Gall, D.1    Susa, I.2
  • 29
    • 0026333684 scopus 로고
    • The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet beta-cells in the isolated perfused rat pancreas
    • Ghosh A, Ronner P, Cheong E, Khalid P, and Matschinsky FM. The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet beta-cells in the isolated perfused rat pancreas. J Biol Chem 266: 22887-22892, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 22887-22892
    • Ghosh, A.1    Ronner, P.2    Cheong, E.3    Khalid, P.4    Matschinsky, F.M.5
  • 30
    • 0036314998 scopus 로고    scopus 로고
    • Control mechanisms of the oscillations of insulin secretion in vitro and in vivo
    • Gilon P, Ravier MA, Jonas JC, and Henquin JC. Control mechanisms of the oscillations of insulin secretion in vitro and in vivo. Diabetes 51: S144-S151, 2002.
    • (2002) Diabetes , vol.51
    • Gilon, P.1    Ravier, M.A.2    Jonas, J.C.3    Henquin, J.C.4
  • 31
    • 0036712559 scopus 로고    scopus 로고
    • Calcium-activated K+ channels of mouse beta-cells are controlled by both store and cytoplasmic Ca2+: Experimental and theoretical studies
    • Goforth PB, Bertram R, Khan FA, Zhang M, Sherman A, and Satin LS. Calcium-activated K+ channels of mouse beta-cells are controlled by both store and cytoplasmic Ca2+: experimental and theoretical studies. J Gen Physiol 120: 307-322, 2002.
    • (2002) J Gen Physiol , vol.120 , pp. 307-322
    • Goforth, P.B.1    Bertram, R.2    Khan, F.A.3    Zhang, M.4    Sherman, A.5    Satin, L.S.6
  • 33
    • 0031737867 scopus 로고    scopus 로고
    • A minimum of fuel is necessary for tolbutamide to mimic the effects of glucose on electrical activity in pancreatic beta-cells
    • Henquin JC. A minimum of fuel is necessary for tolbutamide to mimic the effects of glucose on electrical activity in pancreatic beta-cells. Endocrinology 139: 993-998, 1998.
    • (1998) Endocrinology , vol.139 , pp. 993-998
    • Henquin, J.C.1
  • 34
    • 0026649107 scopus 로고
    • Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic beta cells and HIT cells
    • Hopkins WF, Fatherazi S, Peter-Riesch B, Corkey BE, and Cook DL. Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic beta cells and HIT cells. J Membr Biol 129: 287-295, 1992.
    • (1992) J Membr Biol , vol.129 , pp. 287-295
    • Hopkins, W.F.1    Fatherazi, S.2    Peter-Riesch, B.3    Corkey, B.E.4    Cook, D.L.5
  • 35
    • 0029911186 scopus 로고    scopus 로고
    • The signal transduction function for oxidative phosphorylation is at least second order in ADP
    • Jeneson JA, Wiseman RW, Westerhoff HV, and Kushmerick MJ. The signal transduction function for oxidative phosphorylation is at least second order in ADP. J Biol Chem 271: 27995-27998, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 27995-27998
    • Jeneson, J.A.1    Wiseman, R.W.2    Westerhoff, H.V.3    Kushmerick, M.J.4
  • 40
    • 0036905897 scopus 로고    scopus 로고
    • Glucose-dependent regulation of rhythmic action potential firing in pancreatic beta-cells by K(ATP)-channel modulation
    • Kanno T, Rorsman P, and Gopel SO. Glucose-dependent regulation of rhythmic action potential firing in pancreatic beta-cells by K(ATP)-channel modulation. J Physiol 545: 501-507, 2002.
    • (2002) J Physiol , vol.545 , pp. 501-507
    • Kanno, T.1    Rorsman, P.2    Gopel, S.O.3
  • 41
    • 0033531951 scopus 로고    scopus 로고
    • Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria
    • Kennedy HJ, Pouli AE, Ainscow EK, Jouaville LS, Rizzuto R, and Rutter GA. Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria. J Biol Chem 274: 13281-13291, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 13281-13291
    • Kennedy, H.J.1    Pouli, A.E.2    Ainscow, E.K.3    Jouaville, L.S.4    Rizzuto, R.5    Rutter, G.A.6
  • 43
    • 0343415135 scopus 로고    scopus 로고
    • Parallel oscillations of intracellular calcium activity and mitochondria! membrane potential in mouse pancreatic beta-cells
    • Krippeit-Drews P, Dufer M, and Drews G. Parallel oscillations of intracellular calcium activity and mitochondria! membrane potential in mouse pancreatic beta-cells. Biochem Biophys Res Commun 267: 179-183, 2000.
    • (2000) Biochem Biophys Res Commun , vol.267 , pp. 179-183
    • Krippeit-Drews, P.1    Dufer, M.2    Drews, G.3
  • 44
    • 0027340688 scopus 로고
    • Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells
    • Larsson O, Ammala C, Bokvist K, Fredholm B, and Rorsman P. Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells. J Physiol 463: 349-365, 1993.
    • (1993) J Physiol , vol.463 , pp. 349-365
    • Larsson, O.1    Ammala, C.2    Bokvist, K.3    Fredholm, B.4    Rorsman, P.5
  • 45
    • 0035479916 scopus 로고    scopus 로고
    • i oscillations in mouse pancreatic islets
    • i oscillations in mouse pancreatic islets. Biochem Pharmacol 2: 923-928, 2001.
    • (2001) Biochem Pharmacol , vol.2 , pp. 923-928
    • Lenzen, S.1    Peckmann, T.2
  • 46
    • 27144520388 scopus 로고    scopus 로고
    • 2+ oscillations measured simultaneously in mouse pancreatic islets
    • 2+ oscillations measured simultaneously in mouse pancreatic islets. Biophys J 86, Suppl 1: 470a, 2004.
    • (2004) Biophys J , vol.86 , Issue.SUPPL. 1
    • Luciani, D.S.1    Misler, S.2    Polonsky, K.S.3
  • 48
    • 0346434160 scopus 로고    scopus 로고
    • Citrate oscillates in liver and pancreatic β-cell mitochondria and in INS-1 insulinoma cells
    • MacDonald MJ, Fahien LA, Buss JD, Hasan NM, Fallon MJ, and Kendrick MA. Citrate oscillates in liver and pancreatic β-cell mitochondria and in INS-1 insulinoma cells. J Biol Chem 278: 51894-51900, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 51894-51900
    • MacDonald, M.J.1    Fahien, L.A.2    Buss, J.D.3    Hasan, N.M.4    Fallon, M.J.5    Kendrick, M.A.6
  • 49
    • 0037532705 scopus 로고    scopus 로고
    • Glycolysis and oxidative phosphorylation as a function of cytosolic phosphorylation state and power output of the muscle cell
    • Mader A. Glycolysis and oxidative phosphorylation as a function of cytosolic phosphorylation state and power output of the muscle cell. Eur J Appl Physiol 88: 317-338, 2003.
    • (2003) Eur J Appl Physiol , vol.88 , pp. 317-338
    • Mader, A.1
  • 50
    • 0032488880 scopus 로고    scopus 로고
    • Continuous monitoring of ATP levels in leaving insulin secreting cells expressing cytosolic firefly luciferase
    • Maechler P, Wang H, and Wollheim CP. Continuous monitoring of ATP levels in leaving insulin secreting cells expressing cytosolic firefly luciferase. FEBS Lett 422: 328-332, 1998.
    • (1998) FEBS Lett , vol.422 , pp. 328-332
    • Maechler, P.1    Wang, H.2    Wollheim, C.P.3
  • 51
    • 0031958402 scopus 로고    scopus 로고
    • Model of β-cell mitochondrial calcium handling and electrical activity. I. Cytoplasmic variables
    • Magnus G and Keizer J. Model of β-cell mitochondrial calcium handling and electrical activity. I. Cytoplasmic variables. Am J Physiol Cell Physiol 274: C1158-C1173, 1998.
    • (1998) Am J Physiol Cell Physiol , vol.274
    • Magnus, G.1    Keizer, J.2
  • 52
    • 0031968809 scopus 로고    scopus 로고
    • Model of β-cell mitochondrial calcium handling and electrical activity. II. Mitochondrial variables
    • Magnus G and Keizer J. Model of β-cell mitochondrial calcium handling and electrical activity. II. Mitochondrial variables. Am J Physiol Cell Physiol 274: C1174-C1184, 1998.
    • (1998) Am J Physiol Cell Physiol , vol.274
    • Magnus, G.1    Keizer, J.2
  • 53
    • 0030067124 scopus 로고    scopus 로고
    • A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm
    • Matschinsky FM. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes 45: 223-241, 1996.
    • (1996) Diabetes , vol.45 , pp. 223-241
    • Matschinsky, F.M.1
  • 54
    • 0031892853 scopus 로고    scopus 로고
    • Pancreatic β-cell glucokinase: Closing the gap between theoretical concepts and experimental realities
    • Matschinsky FM, Glaser B, and Magnuson MA. Pancreatic β-cell glucokinase: closing the gap between theoretical concepts and experimental realities. Diabetes 47: 307-315, 1998.
    • (1998) Diabetes , vol.47 , pp. 307-315
    • Matschinsky, F.M.1    Glaser, B.2    Magnuson, M.A.3
  • 55
    • 0032792499 scopus 로고    scopus 로고
    • Characterization of glucokinase mutations associated with maturity-onset diabetes of the young type 2 (MODY-2): Different glucokinase defects lead to a common phenotype
    • Miller SP, Anand GR, Karschnia EJ, Bell GI, LaPorte DC, and Lange AJ. Characterization of glucokinase mutations associated with maturity-onset diabetes of the young type 2 (MODY-2): different glucokinase defects lead to a common phenotype. Diabetes 48: 1645-1651, 1999.
    • (1999) Diabetes , vol.48 , pp. 1645-1651
    • Miller, S.P.1    Anand, G.R.2    Karschnia, E.J.3    Bell, G.I.4    Laporte, D.C.5    Lange, A.J.6
  • 56
    • 0032757926 scopus 로고    scopus 로고
    • 2+ oscillation in pancreatic β-cells
    • 2+ oscillation in pancreatic β-cells. Jpn J Physiol 49: 353-364, 1999.
    • (1999) Jpn J Physiol , vol.49 , pp. 353-364
    • Miwa, Y.1    Imai, Y.2
  • 57
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • Petersen KF, Dufour S, Befroy D, Garcia R, and Shulman GI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350: 664-671, 2004.
    • (2004) N Engl J Med , vol.350 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 61
    • 0036064070 scopus 로고    scopus 로고
    • 2+ contributes to oscillations of the membrane potential in pancreatic beta-cells
    • 2+ contributes to oscillations of the membrane potential in pancreatic beta-cells. Diabetes 51: 376-384, 2002.
    • (2002) Diabetes , vol.51 , pp. 376-384
    • Rolland, J.F.1    Henquin, J.C.2    Gilon, P.3
  • 62
    • 0035143085 scopus 로고    scopus 로고
    • Effects of glucose and amino acids on free ADP in βHC9 insulin-secreting cells
    • Ronner P, Naumann CM, and Friel E. Effects of glucose and amino acids on free ADP in βHC9 insulin-secreting cells. Diabetes 50: 291-300, 2001.
    • (2001) Diabetes , vol.50 , pp. 291-300
    • Ronner, P.1    Naumann, C.M.2    Friel, E.3
  • 63
    • 0035570732 scopus 로고    scopus 로고
    • Nutrient-secretion coupling in the pancreatic islet beta-cell: Recent advances
    • Rutter GA. Nutrient-secretion coupling in the pancreatic islet beta-cell: recent advances. Mol Aspects Med 22: 247-284, 2001.
    • (2001) Mol Aspects Med , vol.22 , pp. 247-284
    • Rutter, G.A.1
  • 65
    • 0029784059 scopus 로고    scopus 로고
    • Contributions of modeling to understanding stimulus-secretion coupling in pancreatic β-cells
    • Sherman A. Contributions of modeling to understanding stimulus-secretion coupling in pancreatic β-cells. Am J Physiol Endocrinol Metab 271: E362-E372, 1996.
    • (1996) Am J Physiol Endocrinol Metab , vol.271
    • Sherman, A.1
  • 66
    • 0036868797 scopus 로고    scopus 로고
    • Glucose-stimulated signaling pathways in biphasic insulin secretion
    • Straub SG and Sharp GW. Glucose-stimulated signaling pathways in biphasic insulin secretion. Diabetes Metab Res Rev 18: 451-463, 2002.
    • (2002) Diabetes Metab Res Rev , vol.18 , pp. 451-463
    • Straub, S.G.1    Sharp, G.W.2
  • 68
    • 0029797652 scopus 로고    scopus 로고
    • Effect of a glucokinase inhibitor on energy production and insulin release in pancreatic islets
    • Sweet IR, Li G, Najafi H, Berner D, and Matschinsky FM. Effect of a glucokinase inhibitor on energy production and insulin release in pancreatic islets. Am J Physiol Endocrinol Metab 271: E606-E625, 1996.
    • (1996) Am J Physiol Endocrinol Metab , vol.271
    • Sweet, I.R.1    Li, G.2    Najafi, H.3    Berner, D.4    Matschinsky, F.M.5
  • 69
    • 0030756468 scopus 로고    scopus 로고
    • Are metabolic oscillations responsible for normal oscillatory insulin secretion?
    • Tornheim K. Are metabolic oscillations responsible for normal oscillatory insulin secretion? Diabetes 46: 1375-1380, 1997.
    • (1997) Diabetes , vol.46 , pp. 1375-1380
    • Tornheim, K.1
  • 71
    • 0037636269 scopus 로고    scopus 로고
    • Model of phosphofructokinase and glycolytic oscillations in the pancreatic beta-cell
    • Westermark PO and Lansner AA. Model of phosphofructokinase and glycolytic oscillations in the pancreatic beta-cell. Biophys J 85: 126-139, 2003.
    • (2003) Biophys J , vol.85 , pp. 126-139
    • Westermark, P.O.1    Lansner, A.A.2
  • 72
    • 0029653395 scopus 로고
    • Human beta-cell glucokinase. Dual role of Ser-151 in catalysis and hexose affinity
    • Xu LZ, Harrison RW, Weber IT, and Pilkis SJ. Human beta-cell glucokinase. Dual role of Ser-151 in catalysis and hexose affinity. J Biol Chem 270: 9939-9946, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 9939-9946
    • Xu, L.Z.1    Harrison, R.W.2    Weber, I.T.3    Pilkis, S.J.4
  • 73
    • 0037961599 scopus 로고    scopus 로고
    • 2+ dynamics of isolated mouse beta-cells and islets: Implications for mathematical models
    • 2+ dynamics of isolated mouse beta-cells and islets: implications for mathematical models. Biophys J 84: 2852-2870, 2003.
    • (2003) Biophys J , vol.84 , pp. 2852-2870
    • Zhang, M.1    Goforth, P.2    Bertram, R.3    Sherman, A.4    Satin, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.