C-terminal tail residue Arg1400 enables NADPH to regulate electron transfer in neuronal nitric-oxide synthase

Journal of Biological Chemistry

Volumn 280, Issue 47, 2005, Pages 39208-39219

  Tiso, Mauro ^a,b   Konas, David W ^a   Panda, Koustubh ^a   Garcin, Elsa D ^c   Sharma, Manisha ^a   Getzoff, Elizabeth D ^c   Stuehr, Dennis J ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CLEVELAND STATE UNIVERSITY   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; CYTOLOGY; IRON COMPOUNDS; NEUROLOGY; NITRIC ACID; PHOSPHATES; PROTEINS; REDUCTION;

CALMODULIN (CAM); CYTOCHROME; ELECTRON FLUX; FLAVIN AUTO-OXIDATION; FLAVOPROTEIN; NEURONAL NITRIC-OXIDE SYNTHASE (NNOS);

BIOCHEMISTRY;

ARGININE; CALMODULIN; CYTOCHROME C; FERRIC ION; FLAVOPROTEIN; GLUTAMIC ACID; HEME; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SERINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; AUTOOXIDATION; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ELECTRON TRANSPORT; ENZYME ACTIVITY; HUMAN; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; REDUCTION; STEADY STATE; WILD TYPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; BASE SEQUENCE; CALMODULIN; DNA, COMPLEMENTARY; ELECTRON TRANSPORT; HEME; HUMANS; KINETICS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NADP; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; OXIDATION-REDUCTION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 28244474850     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M507775200     Document Type: Article

References (78)

1. Ignarro, L. J. (2000) Nitric Oxide: Biology and Pathobiology, 1st Ed., Academic Press, San Diego
2. Moncada, S. (1999) J. R. Soc. Med. 92, 164-169
3. Michel, T., and Feron, O. (1997) J. Clin. Invest. 100, 2146 -2152
4. Mize, R. R. (1998) Nitric Oxide in Brain Development, Plasticity, and Disease, Elsevier, New York
5. Gross, S. S., and Wolin, M. S. (1995) Annu. Rev. Physiol. 57, 737-769
6. Ricciardolo, F. L., Sterk, P. J., Gaston, B., and Folkerts, G. (2004) Physiol. Rev. 84, 731-765
7. Ignarro, L. J., and Napoli, C. (2005) Curr. Diab. Rep. 5, 17-23
8. Stuehr, D. J. (1997) Annu. Rev. Pharmacol. Toxicol. 37, 339-359
9. Masters, B. S., McMillan, K., Sheta, E. A., Nishimura, J. S., Roman, L. J., and Martasek, P. (1996) FASEB J. 10, 552-558
10. Stuehr, D. J. (1999) Biochim. Biophys. Acta 1411, 217-230
11. Alderton, W. K., Cooper, C. E., and Knowles, R. G. (2001) Biochem. J. 357, 593-615
12. Zhang, M., and Vogel, H. J. (1994) J. Biol. Chem. 269, 981-985
13. Aoyagi, M., Arvai, A. S., Tainer, J. A., and Getzoff, E. D. (2003) EMBO J. 22, 766-775
14. Abu-Soud, H. M., and Stuehr, D. J. (1993) Proc. Natl Acad. Sci. U. S. A. 90, 10769-10772
15. Abu-Soud, H. M., Yoho, L. L., and Stuehr, D. J. (1994) J. Biol. Chem. 269, 32047-32050
16. Panda, K., Ghosh, S., and Stuehr, D. J. (2001) J. Biol. Chem. 276, 23349-23356
17. Daff, S., Noble, M. A., Craig, D. H., Rivers, S. L., Chapman, S. K., Munro, A. W., Fujiwara, S., Rozhkova, E., Sagami, I., and Shimizu, T. (2001) Biochem. Soc Trans 29, 147-152
18. Sagami, I., Daff, S., and Shimizu, T. (2001) J. Biol. Chem. 276, 30036-30042
19. Wei, C. C., Crane, B. R., and Stuehr, D. J. (2003) Chem. Rev. 103, 2365-2383
20. Hurshman, A. R., and Marletta, M. A. (2002) Biochemistry 41, 3439-3456
21. Bredt, D. S., Hwang, P. M., Glatt, C. E., Lowenstein, C., Reed, R. R., and Snyder, S. H. (1991) Nature 351, 714-718
22. Zhang, J., Martasek, P., Paschke, R., Shea, T., Siler Masters, B. S., and Kim, J. J. (2001) J. Biol. Chem. 276, 37506-37513
23. Porter, T. D. (1991) Trends Biochem. Sci. 16, 154-158
24. Karplus, P. A., Daniels, M. J., and Herriott, J. R. (1991) Science 251, 60-66
25. Murataliev, M. B., Feyereisen, R., and Walker, F. A. (2004) Biochim. Biophys. Acta 1698, 1-26
26. Wang, M., Roberts, D. L., Paschke, R., Shea, T. M., Masters, B. S., and Kim, J. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 8411-8416
27. Neeli, R., Roitel, O., Scrutton, N. S., and Munro, A. W. (2005) J. Biol. Chem. 280, 17634-17644
28. Matsuda, H., and Iyanagi, T. (1999) Biochim. Biophys. Acta 1473, 345-355
29. Garnaud, P. E., Koetsier, M., Ost, T. W., and Daff, S. (2004) Biochemistry 43, 11035-11044
30. Garcin, E. D., Bruns, C. M., Lloyd, S. J., Hosfield, D. J., Tiso, M., Gachhui, R., Stuehr, D. J., Tainer, J. A., and Getzoff, E. D. (2004) J. Biol. Chem. 279, 37918-37927
31. Newman, E., Spratt, D. E., Mosher, J., Cheyne, B., Montgomery, H. J., Wilson, D. L., Weinberg, J. B., Smith, S. M., Salerno, J. C., Ghosh, D. K., and Guillemette, J. G. (2004) J. Biol. Chem. 279, 33547-33557
32. Craig, D. H., Chapman, S. K., and Daff, S. (2002) J. Biol. Chem. 277, 33987-33994
33. Adak, S., Sharma, M., Meade, A. L., and Stuehr, D. J. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13516-13521
34. Konas, D. W., Zhu, K., Sharma, M., Aulak, K. S., Brudvig, G. W., and Stuehr, D. J. (2004) J. Biol. Chem. 279, 35412-35425
35. Siddhanta, U., Presta, A., Fan, B., Wolan, D., Rousseau, D. L., and Stuehr, D. J. (1998) J. Biol. Chem. 273, 18950-18958
36. Ortiz de Montellano, P. R., Nishida, C., Rodriguez-Crespo, I., and Gerber, N. (1998) Drug Metab. Dispos. 26, 1185-1189
37. Adak, S., Aulak, K. S., and Stuehr, D. J. (2001) J. Biol. Chem. 276, 23246-23252
38. Salerno, J. C., Harris, D. E., Irizarry, K., Patel, B., Morales, A. J., Smith, S. M., Martasek, P., Roman, L. J., Masters, B. S., Jones, C. L., Weissman, B. A., Lane, P., Liu, Q., and Gross, S. S. (1997) J. Biol. Chem. 272, 29769-29777
39. Daff, S., Sagami, I., and Shimizu, T. (1999) J. Biol. Chem. 274, 30589-30595
40. Knudsen, G. M., Nishida, C. R., Mooney, S. D., and Ortiz de Montellano, P. R. (2003) J. Biol. Chem. 278, 31814-31824
41. Roman, L. J., Miller, R. T., de La Garza, M. A., Kim, J. J., and Masters, B. S. (2000) J. Biol. Chem. 275, 21914-21919
42. Roman, L. J., Martasek, P., Miller, R. T., Harris, D. E., de La Garza, M. A., Shea, T. M., Kim, J. J., and Masters, B. S. (2000) J. Biol. Chem. 275, 29225-29232
43. Montgomery, H. J., Romanov, V., and Guillemette, J. G. (2000) J. Biol. Chem. 275, 5052-5058
44. Nishida, C. R., and Ortiz de Montellano, P. R. (2001) J. Biol. Chem. 276, 20116-20124
45. Lane, P., and Gross, S. S. (2002) J. Biol. Chem. 277, 19087-19094
46. Chen, P. F., and Wu, K. K. (2000) J. Biol. Chem. 275, 13155-13163
47. Siddhanta, U., Wu, C., Abu-Soud, H. M., Zhang, J., Ghosh, D. K., and Stuehr, D. J. (1996) J. Biol. Chem. 271, 7309-7312
48. Gachhui, R., Ghosh, D. K., Wu, C., Parkinson, J., Crane, B. R., and Stuehr, D. J. (1997) Biochemistry 36, 5097-5103
49. George, S. E., Su, Z., Fan, D., and Means, A. R. (1993) J. Biol. Chem. 268, 25213-25220
50. George, S. E., Su, Z., Fan, D., Wang, S., and Johnson, J. D. (1996) Biochemistry 35, 8307-8313
51. Su, Z., Blazing, M. A., Fan, D., and George, S. E. (1995) J. Biol. Chem. 270, 29117-29122
52. Kondo, R., Tikunova, S. B., Cho, M. J., and Johnson, J. D. (1999) J. Biol. Chem. 274, 36213-36218
53. Panda, K., Adak, S., Konas, D., Sharma, M., and Stuehr, D. J. (2004) J. Biol. Chem. 279, 18323-18333
54. Stuehr, D. J. (1996) Methods Enzymol. 268, 324-333
55. Adak, S., Ghosh, S., Abu-Soud, H. M., and Stuehr, D. J. (1999) J. Biol. Chem. 274, 22313-22320
56. Adak, S., Santolini, J., Tikunova, S., Wang, Q., Johnson, J. D., and Stuehr, D. J. (2001) J. Biol. Chem. 276, 1244-1252
57. Abu-Soud, H. M., Wang, J., Rousseau, D. L., Fukuto, J. M., Ignarro, L. J., and Stuehr, D. J. (1995) J. Biol. Chem. 270, 22997-23006
58. Knight, K., and Scrutton, N. S. (2002) Biochem. J. 367, 19-30
59. Gachhui, R., Presta, A., Bentley, D. F., Abu-Soud, H. M., McArthur, R., Brudvig, G., Ghosh, D. K., and Stuehr, D. J. (1996) J. Biol. Chem. 271, 20594-20602
60. Noble, M. A., Munro, A. W., Rivers, S. L., Robledo, L., Daff, S. N., Yellowlees, L. J., Shimizu, T., Sagami, I., Guillemette, J. G., and Chapman, S. K. (1999) Biochemistry 38, 16413-16418
61. Santolini, J., Adak, S., Curran, C. M., and Stuehr, D. J. (2001) J. Biol. Chem. 276, 1233-1243
62. Gachhui, R., Abu-Soud, H. M., Ghosha, D. K., Presta, A., Blazing, M. A., Mayer, B., George, S. E., and Stuehr, D. J. (1998) J. Biol. Chem. 273, 5451-5454
63. Batie, C. J., and Kamin, H. (1986) J. Biol. Chem. 261, 11214-11223
64. Tejero, J., Martinez-Julvez, M., Mayoral, T., Luquita, A., Sanz-Aparicio, J., Hermoso, J. A., Hurley, J. K., Tollin, G., Gomez-Moreno, C., and Medina, M. (2003) J. Biol. Chem. 278, 49203-49214
65. Dunford, A. J., Marshall, K. R., Munro, A. W., and Scrutton, N. S. (2004) Eur. J. Biochem. 271, 2548-2560
66. Deng, Z., Aliverti, A., Zanetti, G., Arakaki, A. K., Ottado, J., Orellano, E. G., Calcaterra, N. B., Ceccarelli, E. A., Carrillo, N., and Karplus, P. A. (1999) Nat. Struct. Biol. 6, 847-853
67. Martinez-Julvez, M., Tejero, J., Peregrina, J. R., Nogues, I., Frago, S., Gomez-Moreno, C., and Medina, M. (2005) Biophys. Chem. 115, 219-224
68. Gutierrez, A., Lian, L. Y., Wolf, C. R., Scrutton, N. S., and Roberts, G. C. (2001) Biochemistry 40, 1964-1975
69. Gutierrez, A., Munro, A. W., Grunau, A., Wolf, C. R., Scrutton, N. S., and Roberts, G. C. (2003) Eur. J. Biochem. 270, 2612-2621
70. Guan, Z. W., and Iyanagi, T. (2003) Arch. Biochem. Biophys. 412, 65-76
71. Guan, Z. W., Kamatani, D., Kimura, S., and Iyanagi, T. (2003) J. Biol. Chem. 278, 30859-30868
72. Nogues, I., Tejero, J., Hurley, J. K., Paladini, D., Frago, S., Tollin, G., Mayhew, S. G., Gomez-Moreno, C., Ceccarelli, E. A., Carrillo, N., and Medina, M. (2004) Biochemistry 43, 6127-6137
73. Batie, C. J., and Kamin, H. (1984) J. Biol. Chem. 259, 8832-8839
74. Abu-Soud, H. M., Presta, A., Mayer, B., and Stuehr, D. J. (1997) Biochemistry 36, 10811-10816
75. Stuehr, D. J., Santolini, J., Wang, Z. Q., Wei, C. C., and Adak, S. (2004) J. Biol. Chem. 279, 36167-36170
76. Stevens-Truss, R., Beckingham, K., and Marietta, M. A. (1997) Biochemistry 36, 12337-12345
77. Dimmeler, S., Fleming, I., Fisslthaler, B., Hermann, C., Busse, R., and Zeiher, A. M. (1999) Nature 399, 601-605
78. Fulton, D., Fontana, J., Sowa, G., Gratton, J. P., Lin, M., Li, K. X., Michell, B., Kemp, B. E., Rodman, D., and Sessa, W. C. (2002) J. Biol. Chem. 277, 4277-4284