-
1
-
-
33645523067
-
Prevalence of overweight and obesity in the United States, 1999-2004
-
Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006;295:1549-55.
-
(2006)
JAMA
, vol.295
, pp. 1549-1555
-
-
Ogden, C.L.1
Carroll, M.D.2
Curtin, L.R.3
-
2
-
-
0036745457
-
Mechanisms of obesity-associated cardiovascular and renal disease
-
Hall JE, Crook ED, Jones DW, et al. Mechanisms of obesity-associated cardiovascular and renal disease. Am J Sci 2002;324:127-37.
-
(2002)
Am J Sci
, vol.324
, pp. 127-137
-
-
Hall, J.E.1
Crook, E.D.2
Jones, D.W.3
-
3
-
-
0023204243
-
Incidence and precursors of hypertension in young adults: The Framingham Offspring Study
-
Garrison RJ, Kannel WB, Stokes J, et al. Incidence and precursors of hypertension in young adults: the Framingham Offspring Study. Prev Med 1987;16:235-51.
-
(1987)
Prev Med
, vol.16
, pp. 235-251
-
-
Garrison, R.J.1
Kannel, W.B.2
Stokes, J.3
-
4
-
-
29244465117
-
Fat as an endocrine organ: Relationship to the metabolic syndrome
-
Hutley L, Prins J. Fat as an endocrine organ: relationship to the metabolic syndrome. Am J Med Sci 2005;330:280-9.
-
(2005)
Am J Med Sci
, vol.330
, pp. 280-289
-
-
Hutley, L.1
Prins, J.2
-
5
-
-
0141542617
-
Role of leptin in the regulation of body fluid volume and pressures
-
Guha PK, Villarreal D, Reams GP, et al. Role of leptin in the regulation of body fluid volume and pressures. Am J Ther 2003;10:211-8.
-
(2003)
Am J Ther
, vol.10
, pp. 211-218
-
-
Guha, P.K.1
Villarreal, D.2
Reams, G.P.3
-
6
-
-
18044394757
-
The emerging roles of leptin and ghrelin in cardiovascular physiology and pathophysiology
-
Sharma V, McNeill J. The emerging roles of leptin and ghrelin in cardiovascular physiology and pathophysiology. Curr Vasc Pharmacol 2005;3:169-80.
-
(2005)
Curr Vasc Pharmacol
, vol.3
, pp. 169-180
-
-
Sharma, V.1
McNeill, J.2
-
7
-
-
33646360219
-
Role of leptin in blood pressure regulation and arterial hypertension
-
Beltowski J. Role of leptin in blood pressure regulation and arterial hypertension. J Hypertens 2006;24:789-901.
-
(2006)
J Hypertens
, vol.24
, pp. 789-901
-
-
Beltowski, J.1
-
8
-
-
0030876805
-
Receptor-mediated regional sympathetic nerve activation by leptin
-
Haynes WG, Morgan DA, Walsh SA, et al. Receptor-mediated regional sympathetic nerve activation by leptin. J Clin Invest 1997;100:270-8.
-
(1997)
J Clin Invest
, vol.100
, pp. 270-278
-
-
Haynes, W.G.1
Morgan, D.A.2
Walsh, S.A.3
-
9
-
-
0030830662
-
Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats
-
Dunbar JC, Hu Y, Lu H. Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats. Diabetes 1997;46:2040-3.
-
(1997)
Diabetes
, vol.46
, pp. 2040-2043
-
-
Dunbar, J.C.1
Hu, Y.2
Lu, H.3
-
10
-
-
0032440815
-
Renal effects of leptin in normotensive, hypertensive and obese rats
-
Villarreal D, Reams G, Freeman RH, et al. Renal effects of leptin in normotensive, hypertensive and obese rats. Am J of Physiol 1998;275:R2056-60.
-
(1998)
Am J of Physiol
, vol.275
-
-
Villarreal, D.1
Reams, G.2
Freeman, R.H.3
-
11
-
-
11244349747
-
Obesity-associated hypertension: New insights into mechanisms
-
Rahmouni K, Correia LG, Haynes W, et al. Obesity-associated hypertension: new insights into mechanisms. Hypertension 2005;45:9-14.
-
(2005)
Hypertension
, vol.45
, pp. 9-14
-
-
Rahmouni, K.1
Correia, L.G.2
Haynes, W.3
-
12
-
-
0033978467
-
Leptin induces direct vasodilation through distinct endothelial mechanisms
-
Lembo L, Vecchione C, Fratta L. Leptin induces direct vasodilation through distinct endothelial mechanisms. Diabetes 2000;49:293-7.
-
(2000)
Diabetes
, vol.49
, pp. 293-297
-
-
Lembo, L.1
Vecchione, C.2
Fratta, L.3
-
13
-
-
0036091969
-
Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway
-
Vecchione C, Maffei A, Colella S, et al. Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway. Diabetes 2002;51:168-73.
-
(2002)
Diabetes
, vol.51
, pp. 168-173
-
-
Vecchione, C.1
Maffei, A.2
Colella, S.3
-
14
-
-
0037907471
-
Pivotal role of nitric oxide in the control of blood pressure after leptin administration
-
Fruhbeck G. Pivotal role of nitric oxide in the control of blood pressure after leptin administration. Diabetes 1999;48:903-8.
-
(1999)
Diabetes
, vol.48
, pp. 903-908
-
-
Fruhbeck, G.1
-
15
-
-
0035725056
-
Does leptin stimulate nitric oxide to oppose the effects of sympathetic activation?
-
Mitchell JL, Morgan DA, Correia ML, et al. Does leptin stimulate nitric oxide to oppose the effects of sympathetic activation? Hypertension 2001;38:1081-6.
-
(2001)
Hypertension
, vol.38
, pp. 1081-1086
-
-
Mitchell, J.L.1
Morgan, D.A.2
Correia, M.L.3
-
16
-
-
0034121709
-
Regional hemodynamic effects of recombinant murine or human leptin in conscious rats
-
Gardiner SM, Kemp PA, March JE, et al. Regional hemodynamic effects of recombinant murine or human leptin in conscious rats. Br J Pharmacol 2000;130:805-10.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 805-810
-
-
Gardiner, S.M.1
Kemp, P.A.2
March, J.E.3
-
17
-
-
0037023656
-
Leptin induces endothelin-1 endothelial cells in vitro
-
Quehenberger P, Exner M, Sunder-Plassmann R, et al. Leptin induces endothelin-1 endothelial cells in vitro. Circ Res 2002;90:711-8.
-
(2002)
Circ Res
, vol.90
, pp. 711-718
-
-
Quehenberger, P.1
Exner, M.2
Sunder-Plassmann, R.3
-
18
-
-
0032999682
-
Leptin induces oxidative stress in human endothelial cells
-
Bouloumine A, Marumo T, Lofanton M, et al. Leptin induces oxidative stress in human endothelial cells. FASEB J 1999;13:1231-8.
-
(1999)
FASEB J
, vol.13
, pp. 1231-1238
-
-
Bouloumine, A.1
Marumo, T.2
Lofanton, M.3
-
19
-
-
0036066483
-
The concept of selective leptin resistance: Evidence from agouti yellow obese mice
-
Correia MI, Haynes WG, Rahmouni K. The concept of selective leptin resistance: evidence from agouti yellow obese mice. Diabetes 2002;51:439-42.
-
(2002)
Diabetes
, vol.51
, pp. 439-442
-
-
Correia, M.I.1
Haynes, W.G.2
Rahmouni, K.3
-
20
-
-
0031606279
-
Chronic leptin infusion increases arterial pressure
-
Shek EW, Brands MW, Hall JE. Chronic leptin infusion increases arterial pressure. Hypertension 1998;31:409-14.
-
(1998)
Hypertension
, vol.31
, pp. 409-414
-
-
Shek, E.W.1
Brands, M.W.2
Hall, J.E.3
-
21
-
-
0035094738
-
Inhibition of NO synthesis enhances chronic cardiovascular and renal actions of leptin
-
Kuo JJ, Jones O, Hall J. Inhibition of NO synthesis enhances chronic cardiovascular and renal actions of leptin. Hypertension 2001;1:37:670-6.
-
(2001)
Hypertension
, vol.1
, Issue.37
, pp. 670-676
-
-
Kuo, J.J.1
Jones, O.2
Hall, J.3
-
22
-
-
12944257370
-
Pathophysiological role of leptin in obesity-related hypertension
-
Aizawa-Abe M, Ogawa Y, Masuzaki H, et al. Pathophysiological role of leptin in obesity-related hypertension. J Clin Invest 2000;105:1243-52.
-
(2000)
J Clin Invest
, vol.105
, pp. 1243-1252
-
-
Aizawa-Abe, M.1
Ogawa, Y.2
Masuzaki, H.3
-
23
-
-
0031052428
-
Characterization and localization of leptin receptors in the rat kidney
-
Serradeil-Le G, Raufaste D, Brossard G, et al. Characterization and localization of leptin receptors in the rat kidney. FEBS Lett 1997;404:185-91.
-
(1997)
FEBS Lett
, vol.404
, pp. 185-191
-
-
Serradeil-Le, G.1
Raufaste, D.2
Brossard, G.3
-
24
-
-
0032552112
-
The stomach is a source of leptin
-
Bado A, Levasseur S, Attoub S, et al. The stomach is a source of leptin. Nature 1998;394:790-3.
-
(1998)
Nature
, vol.394
, pp. 790-793
-
-
Bado, A.1
Levasseur, S.2
Attoub, S.3
-
25
-
-
0030771886
-
Human leptin has natriuretic activity in the rat
-
Jackson EK, Li P. Human leptin has natriuretic activity in the rat. Am J Physiol 1997;272:333-8.
-
(1997)
Am J Physiol
, vol.272
, pp. 333-338
-
-
Jackson, E.K.1
Li, P.2
-
26
-
-
0033849818
-
Effects of renal denervation on the sodium excretory action of leptin in hypertensive rats
-
Villarreal D, Reams G, Freeman RH. Effects of renal denervation on the sodium excretory action of leptin in hypertensive rats. Kidney Int 2000;58:989-94.
-
(2000)
Kidney Int
, vol.58
, pp. 989-994
-
-
Villarreal, D.1
Reams, G.2
Freeman, R.H.3
-
27
-
-
0036280459
-
+-ATPase activity in the rat-impaired effect in dietary-induced obesity
-
+-ATPase activity in the rat-impaired effect in dietary-induced obesity. Med Sci Monit 2002;8:BR221-9.
-
(2002)
Med Sci Monit
, vol.8
-
-
Beltowski, J.1
Wojcicka, G.2
-
28
-
-
4644363328
-
Effects of chronic nitric oxide inhibition on the renal excretory response to leptin
-
Villarreal D, Reams G, Samar H, et al. Effects of chronic nitric oxide inhibition on the renal excretory response to leptin. Obes Res 2004;12:1006-10.
-
(2004)
Obes Res
, vol.12
, pp. 1006-1010
-
-
Villarreal, D.1
Reams, G.2
Samar, H.3
-
29
-
-
33645758046
-
Leptin blockade attenuates sodium excretion in saline-loaded normotensive rats
-
Villarreal D, Reams G, Samar H. Leptin blockade attenuates sodium excretion in saline-loaded normotensive rats. Mol Cell Biochem 2006;283:153-7.
-
(2006)
Mol Cell Biochem
, vol.283
, pp. 153-157
-
-
Villarreal, D.1
Reams, G.2
Samar, H.3
-
30
-
-
0141478841
-
Effect of salt on hypertension and oxidative stress in rat model on diet-induced obesity
-
Dobrian AD, Schriver SD, Lynch T, et al. Effect of salt on hypertension and oxidative stress in rat model on diet-induced obesity. Am J Physiol 2003;285:F619-28.
-
(2003)
Am J Physiol
, vol.285
-
-
Dobrian, A.D.1
Schriver, S.D.2
Lynch, T.3
-
31
-
-
0030965884
-
Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
-
Emilsson V, Liu YL, Cawthorne MA, et al. Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 1997;46:313-36.
-
(1997)
Diabetes
, vol.46
, pp. 313-336
-
-
Emilsson, V.1
Liu, Y.L.2
Cawthorne, M.A.3
-
32
-
-
0035179087
-
Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity
-
Konstantinides S, Schafer K, Koschnick S, et al. Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity. J Clin Invest 2001;108:1533-40.
-
(2001)
J Clin Invest
, vol.108
, pp. 1533-1540
-
-
Konstantinides, S.1
Schafer, K.2
Koschnick, S.3
-
33
-
-
0032508682
-
Biological action of leptin as an angiogenic factor
-
Sierra-Honigmann MR, Nath AK, Murakami C, et al. Biological action of leptin as an angiogenic factor, Science 1998;281:1683-6.
-
(1998)
Science
, vol.281
, pp. 1683-1686
-
-
Sierra-Honigmann, M.R.1
Nath, A.K.2
Murakami, C.3
-
34
-
-
0030736770
-
Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells
-
Umemoto Y, Tsuji K, Yang FC, et al. Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells. Blood 1997;90:3438-43.
-
(1997)
Blood
, vol.90
, pp. 3438-3443
-
-
Umemoto, Y.1
Tsuji, K.2
Yang, F.C.3
-
35
-
-
0032707747
-
Plasma leptin level is associated with myocardial wall thickness in hypertensive insulin resistant men
-
Paolisso G, Tangliamonte MR, Galderisi M, et al. Plasma leptin level is associated with myocardial wall thickness in hypertensive insulin resistant men. Hypertension 1999;34:1047-52.
-
(1999)
Hypertension
, vol.34
, pp. 1047-1052
-
-
Paolisso, G.1
Tangliamonte, M.R.2
Galderisi, M.3
-
37
-
-
0041857804
-
The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes
-
Rajapurohitam V, Gan XT, Kirshenbaum LA, et al. The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes. Circ Res 2003;93:277-9.
-
(2003)
Circ Res
, vol.93
, pp. 277-279
-
-
Rajapurohitam, V.1
Gan, X.T.2
Kirshenbaum, L.A.3
-
38
-
-
0042018759
-
Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice
-
Barouch LA, Berkowitz DE, Harrison RW, et al. Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice. Circulation 2003;108:754-9.
-
(2003)
Circulation
, vol.108
, pp. 754-759
-
-
Barouch, L.A.1
Berkowitz, D.E.2
Harrison, R.W.3
-
39
-
-
1642464978
-
Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase-and phosphatidylinositol 3-kinase-dependent signaling pathways
-
Tajmir P, Ceddia RB, Li RK, et al. Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase-and phosphatidylinositol 3-kinase-dependent signaling pathways; Endocrinology 2004;145:1550-5.
-
(2004)
Endocrinology
, vol.145
, pp. 1550-1555
-
-
Tajmir, P.1
Ceddia, R.B.2
Li, R.K.3
-
40
-
-
0037119410
-
Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylasemalonyl-CoA axis
-
Atkinson LL, Fischer MA, Lopaschuk GD. Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylasemalonyl-CoA axis. J Biol Chem 2002;277:29424-30.
-
(2002)
J Biol Chem
, vol.277
, pp. 29424-29430
-
-
Atkinson, L.L.1
Fischer, M.A.2
Lopaschuk, G.D.3
-
41
-
-
0033775092
-
Leptin attenuates cardiac contraction in rat ventricular myocytes: Role of
-
Nickola M, Wold L, Colligan P, et al. Leptin attenuates cardiac contraction in rat ventricular myocytes: role of NO hypertension 2000;36:501-5.
-
(2000)
hypertension
, vol.36
, pp. 501-505
-
-
Nickola, M.1
Wold, L.2
Colligan, P.3
-
43
-
-
0036157726
-
Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: Role of JAK/STAT pathway
-
Wold LE, Relling DP, Duan J, et al. Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of JAK/STAT pathway. Hypertension 2002;39:69-74.
-
(2002)
Hypertension
, vol.39
, pp. 69-74
-
-
Wold, L.E.1
Relling, D.P.2
Duan, J.3
-
44
-
-
2442696860
-
Role of leptin in the development of cardiac hypertrophy in experimental animals and humans
-
Tritos NA, Manning WJ, Danias PG, et al. Role of leptin in the development of cardiac hypertrophy in experimental animals and humans. Circulation 2004;109:e67.
-
(2004)
Circulation
, vol.109
-
-
Tritos, N.A.1
Manning, W.J.2
Danias, P.G.3
-
45
-
-
12244309089
-
Elevated serum levels of leptin and soluble leptin receptor in patients with advanced chronic heart failure
-
Schulze PC, Kratzsch J, Linke A, et al. Elevated serum levels of leptin and soluble leptin receptor in patients with advanced chronic heart failure. Eur J Heart Fail 2003;5:33-40.
-
(2003)
Eur J Heart Fail
, vol.5
, pp. 33-40
-
-
Schulze, P.C.1
Kratzsch, J.2
Linke, A.3
-
46
-
-
0029067621
-
Prospective study of intentional weight loss and mortality in never smoking overweight US white women aged 40-64
-
Williamson DF, Pamuk E, Thun M, et al. Prospective study of intentional weight loss and mortality in never smoking overweight US white women aged 40-64. Am J Epidemiol 1995;141:1128-41.
-
(1995)
Am J Epidemiol
, vol.141
, pp. 1128-1141
-
-
Williamson, D.F.1
Pamuk, E.2
Thun, M.3
-
47
-
-
0035793139
-
Long term weight loss and changes in blood pressure: Results of the trials of hypertension prevention, phase II
-
Stevens VJ, Obarzanek E, Cook NR, et al. Long term weight loss and changes in blood pressure: results of the trials of hypertension prevention, phase II. Ann Intern Med 2001;134:1-11.
-
(2001)
Ann Intern Med
, vol.134
, pp. 1-11
-
-
Stevens, V.J.1
Obarzanek, E.2
Cook, N.R.3
-
49
-
-
0034739524
-
AHA Dietary Guidelines: Revision 2000
-
Krauss RM, Eckel RH, Howard B, et al. AHA Dietary Guidelines: revision 2000. Circulation 2000;102:2284-99.
-
(2000)
Circulation
, vol.102
, pp. 2284-2299
-
-
Krauss, R.M.1
Eckel, R.H.2
Howard, B.3
-
50
-
-
0028959193
-
Changes in energy expenditure resulting from altered body weight
-
Liebel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med 1995;332:621-8.
-
(1995)
N Engl J Med
, vol.332
, pp. 621-628
-
-
Liebel, R.L.1
Rosenbaum, M.2
Hirsch, J.3
-
51
-
-
15944373229
-
Pharmacologic and surgical management of obesity in primary care: A clinical practice guideline from the American College of Physicians
-
Snow V, Barry P, Fitterman N, et al. Pharmacologic and surgical management of obesity in primary care: a clinical practice guideline from the American College of Physicians. Ann Intern Med 2005;142:525-31.
-
(2005)
Ann Intern Med
, vol.142
, pp. 525-531
-
-
Snow, V.1
Barry, P.2
Fitterman, N.3
-
52
-
-
15944367788
-
Meta-analysis: Pharmacologic treatment of obesity
-
Li Z, Maglione M, Tu W, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med 2005;142:532-46.
-
(2005)
Ann Intern Med
, vol.142
, pp. 532-546
-
-
Li, Z.1
Maglione, M.2
Tu, W.3
-
53
-
-
33745506695
-
New approaches for the management of patients with multiple cardiometabolic risk factors
-
Van Gaal LF, Peiffer F. New approaches for the management of patients with multiple cardiometabolic risk factors. J Endocrinol Invest 2006;29:83-9.
-
(2006)
J Endocrinol Invest
, vol.29
, pp. 83-89
-
-
Van Gaal, L.F.1
Peiffer, F.2
-
55
-
-
0035072525
-
Choice of drug treatment for obesity-related hypertension: Where is the evidence?
-
Sharma AM, Pischon T, Engeli S, et al. Choice of drug treatment for obesity-related hypertension: where is the evidence? J Hypertens 2001;19:667-74.
-
(2001)
J Hypertens
, vol.19
, pp. 667-674
-
-
Sharma, A.M.1
Pischon, T.2
Engeli, S.3
-
57
-
-
1342302883
-
Sympathetic activity and response to ACE inhibitor (Enalapril) in normotensive obese and nonobese subjects
-
Amador N, Guizar J-M, Malacara J-M, et al. Sympathetic activity and response to ACE inhibitor (Enalapril) in normotensive obese and nonobese subjects, Arch Med Res 2004;35: 54-8.
-
(2004)
Arch Med Res
, vol.35
, pp. 54-58
-
-
Amador, N.1
Guizar, J.-M.2
Malacara, J.-M.3
-
58
-
-
20444479426
-
Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients
-
Forgari R, Derosa G, Zoppi A, et al. Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients. Hypertens Res 2005;28:209-14.
-
(2005)
Hypertens Res
, vol.28
, pp. 209-214
-
-
Forgari, R.1
Derosa, G.2
Zoppi, A.3
|