Applications and safety of microbial oils in food

Modifying Lipids for Use in Food

Volumn , Issue , 2006, Pages 567-586

  Ratledge, C ^a   Hopkins, S ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 34447520179     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1533/9781845691684.3.567     Document Type: Chapter

References (76)

1. Abril R., Barclay W. Production of docosahexaenoic acid-enriched poultry eggs and meat using an algae-based feed ingredient. World Rev Nutr Diet 1998, 83:77-88.
2. tm) in laying hen feed for the production of DHA. Enriched eggs. Egg Nutrition and Biotechnology 2000, 197-202. CAB International, Wallingford. J.S. Sim, S. Nakai, W. Guenter (Eds.).
3. Abril R., Garrett J., Zeller S.G., Sander W.J., Mast R.W. Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 2003, 37(1):73-82.
4. Arterburn L.M., Boswell K.D., Lawlor T., Cifone M.A., Murli H., Kyle D.J. In vitro genotoxicity testing of Arasco and Dhasco oils. Food Chem Toxicol 2000, 38(11):971-976.
5. Babcock T., Helton W.S., Espat N.J. Eicosapentaenoic acid (EPA): an antiinflammatory omega-3 fat with potential clinical applications. Nutrition 2000, 16(11-12):1116-1118.
6. Barclay W., Zeller S. Nutritional enhancement of n-3 and n-6 fatty acids in rotifers and artemia nauplii by feeding spray-dried Schizochytrium sp. J World Aquacult Soc 1996, 27(3):314-322.
7. Barclay W., Abril R., Abril P., Weaver C., Ashford A. Production of docosahexaenoic acid from microalgae and its benefits for use in animal feeds. World Rev Nutr Diet 1998, 83:61-76.
8. Barclay W.R., Weaver C., Metz J. Development of a docosahexaenoic acid production technology using Schizochytrium: a historical perspective. Single Cell Oils 2005, 36-52. AOCS Press, Champaign, Ill. Z. Cohen, C. Ratledge (Eds.).
9. Borod E., Atkinson R., Barclay W.R., Carlson S.E. Effects of third trimester consumption of eggs high in docosahexaenoic acid on docosahexaenoic acid status and pregnancy. Lipids 1999, 34:S231. Suppl).
10. Brash A.R. Arachidonic acid as a bioactive molecule. J Clin Invest 2001, 107(11):1339-1345.
11. Brown M.R. Nutritional value of microalgae for aquaculture. Avances en Nutrición Acuícola VI. Memorias del VI, Simposium Internacional de Nutrición Acuícola 2002, 3 al 6 de Septiembre del 2002, Cancún, Quintana Roo, México. L.E. Cruz-Suárez, D. Ricque-Marie, M. Tapia-Salazar, M.G. Gaxiola-Cortés, N. Simoes (Eds.).
12. Bucher H.C., Hengstler P., Schindler C., Meier G. N-3 polyunsaturated fatty acids in coronary heart disease: A meta-analysis of randomized controlled trials. Am J Med 2002, 112:298-304.
13. Burdge G.C., Jones A.E., Wootton S.A. Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men. Br J Nutr 2002, 88(4):355-363.
14. Burns R.A., Wibert G.J., Diersen-Schade D.A., Kelly C.M. Evaluation of single-cell sources of docosahexaenoic acid and arachidonic acid: 3-month rat oral safety study with an in utero phase. Food Chem Toxicol 1999, 37(1):23-36.
15. Carlson S.E. The role of PUFA in infant nutrition. INFORM 1995, 6(8):940-946.
16. Connor W.E. Importance of n-3 fatty acids in health and disease. Am J Clin Nutr 2000, 71(1 Suppl):171S-175S.
17. Crawford M.A., Golfetto I., Ghebremeskel K., Min Y., Moodley T., Poston L., Phylactos A., Cunnane S., Schmidt W. The potential role for arachidonic and docosahexaenoic acids in protection against some central nervous system injuries in preterm infants. Lipids 2003, 38(4):303-315.
18. Ewin J. Fine wines & fish oil: The life of Hugh MacDonald Sinclair 2001, Oxford University Press, Oxford, New York.
19. Farquharson J., Jamieson E.C., Abbasi K.A., Patrick W.J., Logan R.W., Cockburn F. Effect of diet on the fatty acid composition of the major phospholipids of infant cerebral cortex. Arch Dis Child 1995, 72(3):198-203.
20. Farrell D.J. Enrichment of hen eggs with n-3 long-chain fatty acids and evaluation of enriched eggs in humans. Am J Clin Nutr 1998, 68(3):538-544.
21. Forsyth J.S., Willatts P., Agostoni C., Bissenden J., Casaer P., Boehm G. Long chain polyunsaturated fatty acid supplementation in infant formula and blood pressure in later childhood: follow up of a randomised controlled trial. BMJ 2003, 326(7396):953.
22. Fsanz DHASCO and ARASCO oils as sources of long-chain polyunsaturated fatty acids in infant formula: A safety assessment Technical report series No. 22, Food Standards Australia New Zealand, available at. http://www.foodstandards.gov.au/_srcfilesDHASCO%20and%20ARASCO%20in%20infant%20formula.pdf.
23. Gibson R.A., Makrides M., Neumann M.A., Simmer K., Mantzioris E., James M.J. Ratios of linoleic acid to alpha-linolenic acid in formulas for term infants. J Pediatr 1994, 125(5 Pt 2):S48-55.
24. Gibson R.A., Neumann M.A., Makrides M. The effects of diets rich in docosahexaenoic acid and/or γ-linolenic acid on plasma fatty acid profiles in term infants. Lipids in Infant Nutrition 1998, 19-28. AOCS Press, Champaign, Ill. Y.-S. Huang, A. Sinclair (Eds.).
25. Hammond B.G., Mayhew D.A., Holson J.F., Nemec M.D., Mast R.W., Sander W.J. Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 2001, 33(2):205-217.
26. Hammond B.G., Mayhew D.A., Naylor M.W., Ruecker F.A., Mast R.W., Sander W.J. Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 2001, 33(2):192-204.
27. Hammond B.G., Mayhew D.A., Robinson K., Mast R.W., Sander W.J. Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 2001, 33(3):356-362.
28. Hammond B.G., Mayhew D.A., Kier L.D., Mast R.W., Sander W.J. Safety assessment of DHA-rich microalgae from Schizochytrium sp. Regul Toxicol Pharmacol 2002, 35(2 Pt 1):255-265.
29. Harel M., Koven W., Lein I., Bar Y., Behrens P., Stubblefield J., Zohar Y., Place A.R. Advanced DHA, EPA and ARA enrichment materials for marine aquaculture using single cell heterotrophs. Aquaculture 2002, 213(1-4):347-362.
30. Haumann B. Alternative sources for n-3 fatty acids. INFORM 1998, 9(12):1108-1119.
31. Hempenius R.A., Van Delft J.M., Prinsen M., Lina B.A. Preliminary safety assessment of an arachidonic acid-enriched oil derived from Mortierella alpina: summary of toxicological data. Food Chem Toxicol 1997, 35(6):573-581.
32. Hempenius R.A., Lina B.A., Haggitt R.C. Evaluation of a subchronic (13-week) oral toxicity study, preceded by an in utero exposure phase, with arachidonic acid oil derived from Mortierella alpina in rats. Food Chem Toxicol 2000, 38(2-3):127-139.
33. Hoffman D., Uauy R. Essentiality of dietary omega 3 fatty acids for premature infants: plasma and red blood cell fatty acid composition. Lipids 1992, 27:886-895.
34. Horrobin D.F. Cardiovascular disease, affective disorders and impaired fatty acid and phospholipid metabolism. Vascular Disease and Affective Disorders 2002, 75-94. London, Martin Dunitz. E.A. Chiu, O. Ames, C. Katona (Eds.).
35. Horrocks L.A., Yeo Y.K. Health benefits of docosahexaenoic acid (DHA). Pharmacol Res 1999, 40(3):211-225.
36. Huang M.C., Chao A., Kirwan R., Tschanz C., Peralta J.M., Diersen-Schade D.A., Cha S., Brenna J.T. Negligible changes in piglet serum clinical indicators or organ weights due to dietary single-cell long-chain polyunsaturated oils. Food Chem Toxicol 2002, 40(4):453-460.
37. Huang Y.-S., Sinclair A. Lipids in Infant Nutrition 1998, AOCS Press, Champaign, Ill.
38. Huang Y.-S., Ziboh V.A. γ-Linolenic Acid: Recent Advances in Biotechnology and Clinical Applications 2001, AOCS Press, Champaign, Ill.
39. Keller J.R. Omega-3 fatty acids may be effective in the treatment of depression. Topics Clin Nutr 2002, 17(5):21-27.
40. Kiy T., Rusing M., Fabritius D. Production of docosahexaenoic acid by the marine microalga. Single Cell Oils 2005, 99-106. AOCS Press, Champaign, Ill, Ulkenia sp. Z. Cohen, C. Ratledge (Eds.).
41. Krawczyk T. Do infants need extra DHA, AA?. INFORM 2001, 12(11):1064-1074.
42. Kris-Etherton P.M., Harris W.S., Appel L.J. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002, 106(21):2747-2757.
43. Kroes R., Schaefer E.J., Squire R.A., Williams G.M. A review of the safety of DHA45-oil. Food Chem Toxicol 2003, 41(11):1433-1446.
44. Kyle D.J. Safety and bioavailability of single cell oil enriched in arachidonic acid. Lipid Technol Newsl 1997, 3(5):100-103.
45. Kyle D.J. Production and use of a single cell oil highly enriched in arachidonic acid. Lipid Technol 1997, 9:116-121.
46. Kyle D.J. The large-scale production and use of a single-cell oil highly enriched in docosahexaenoic acid. Omega-3 Fatty Acids: Chemistry, Nutrition and Health Effects 2001, 92-107. American Chemical Society, Washington, DC, ACS Symposium Series 788. F. Shahidi, J.W. Finley (Eds.).
47. Leaf A., Kang J.X., Xiao Y.F., Billman G.E. Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils. Circulation 2003, 107(21):2452-2646.
48. Lewis T.E., Nichols P.D., Mcmeekin T.A. The biotechnological potential of thraustochytrids. Mar Biotechnol (NY) 1999, 1(6):580-587.
49. Marchioli R., Schweiger C., Tavazzi L., Valagussa F. Efficacy of n-3 polyunsaturated fatty acids after myocardial infarction: results of gissi-prevenzione trial. Gruppo italiano per lo studio della sopravvivenza nell'infarto miocardico. Lipids 2001, 36:S119-S126. (Suppl).
50. Marchioli R., Barzi F., Bomba E., et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction. Circulation 2002, 5(16):1897-1903.
51. Marriott N.G., Garrett J.E., Sims M.D., Abril J.R. Performance characteristics and fatty acid composition of pigs fed a diet with docosahexaenoic acid. J Muscle Foods 2002, 13(4):265-277.
52. Marriott N.G., Garrett J.E., Sims M.D., Wang H., Abril J.R. Characteristics of pork with docosahexaenoic acid supplemented in the diet. J Muscle Foods 2002, 13(4):253-263.
53. Nordoy A. Dietary fatty acids and coronary heart disease. Lipids 1999, 34:S19-S22. Suppl).
54. Otto S.J., Van Houwelingen A.A.C., Hornstra G. The effect of supplementation with docosahexaenoic and arachidonic acid derived from single cell oils on plasma and erythrocyte fatty acids of pregnant women in the second trimester. Prostaglandins Leukot Essent Fatty Acids 2000, 63(5):323-328.
55. Palakurthi S.S., Fluckiger R., Aktas H., Changolkar A.K., Shahsafaei A., Harneit S., Kilic E., Halperin J.A. Inhibition of translation initiation mediates the anticancer effect of the n-3 polyunsaturated fatty acid eicosapentaenoic acid. Cancer Res 2000, 60(11):2919-2925.
56. Puri B.K. Monomodal rigid-body registration and applications to the investigation of the effects of eicosapentaenoic acid intervention in neuropsychiatric disorders. Prostaglandins Leukot Essent Fatty Acids 2004, 71(3):177-179.
57. Rahman M., Wright J.T., Douglas J.G. The role of the cytochrome p450-dependent metabolites of arachidonic acid in blood pressure regulation and renal function: a review. Am J Hypertens 1997, 10(3):356-365.
58. Ratledge C. Single cell oils for the 21st century. Single Cell Oils 2005, 1-20. AOCS Press, Champaign, Ill. Z. Cohen, C. Ratledge (Eds.).
59. Reitan K.I., Rainuzzo J.R., Oie G., Olsen Y. A review of the nutritional effects of algae in marine fish larvae. Aquaculture 1997, 155(1-4):207-221.
60. Ruxton C.H., Reed S.C., Simpson M.J., Millington K.J. The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence. J Hum Nutr Diet 2004, 17(5):449-459.
61. Sangiovanni J.P., Chew E.Y. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res 2005, 24(1):87-138.
62. Schmidt E.B., Christensen J.H., Aardestrup I., Madsen T., Riahi S., Hansen V.E., Skou H.A. Marine n-3 fatty acids: basic features and background. Lipids 2001, 36(Suppl):S65-68.
63. Seyberth H.W., Oelz O., Kennedy T., Sweetman B.J., Danon A., Frolich J.C., Heimberg M., Oates J.A. Increased arachidonate in lipids after administration to man: effects on prostaglandin biosynthesis. Clin Pharmacol Ther 1975, 18(5 Pt 1):521-529.
64. Siddiqui R.A., Shaikh S.R., Sech L.A., Yount H.R., Stillwell W., Zaloga G.P. Omega 3-fatty acids: health benefits and cellular mechanisms of action. Mini Rev Med Chem 2004, 4(8):859-871.
65. Sinclair A., Attar-Bashi N., Anura Jayasooriya, Gibson R., Makrides M. Nutritional aspects of single cell oils: Uses and applications of arachidonic acid and docosahexaenoic acid oils. Single Cell Oils 2005, 182-201. AOCS Press, Champaign, Ill. Z. Cohen, C. Ratledge (Eds.).
66. Sinclair A.J. Long-chain polyunsaturated fatty acids in the mammalian brain. Proc Nutr Soc 1975, 34(3):287-291.
67. Sinclair H.M. The diet of Canadian indians and eskimos. Proc Nutr Soc 1953, 12:69-82.
68. Smuts C.M., Borod E., Peeples J.M., Carlson S.E. High-DHA eggs: feasibility as a means to enhance circulating DHA in mother and infant. Lipids 2003, 38(4):407-414.
69. Streekstra H. On the safety of Mortierella alpina for the production of food ingredients, such as arachidonic acid. J Biotechnol 1997, 56(3):153-165.
70. Tam P.S.Y., Umeda-Sawada R., Yaguchi T., Akimoto K., Kiso Y., Igarashi O. The metabolism and distribution of docosapentaenoic acid (n-6) in rats and rat hepatocytes. Lipids 2000, 35(1):71-75.
71. Uauy R., Birch D., Birch E., Tyson J., Hoffman D. Effect of dietary omega-3 fatty acids on retinal function of very-low-birth-weight neonates. Pediatr Res 1990, 28:485-492.
72. Watkins C. Infant formula update. INFORM 2004, 15(6):381-382.
73. Wen Z., Chen F. Prospects for eicosapentaenoic acid production using microorganisms. Single Cell Oils 2005, 138-160. AOCS Press, Champaign, Ill. Z. Cohen, C. Ratledge (Eds.).
74. Wheeler T.G., Benolken R.M., Anderson R.E. Visual membranes: specificity of fatty acid precursors for the electrical response to illumination. Science 1975, 188(4195):1312-1314.
75. Wynn J.P., Ratledge C. Microbial production of oils and fats. Food Biotechnology 2005, 443-472. CRC Press, Boca Raton, FL. K. Shetty (Ed.).
76. Zeller S. Safety evaluation of single cell oils and the regulatory requirements for use as food ingredients. Single Cell Oils 2005, 161-181. AOCS Press, Champaign, Ill. Z. Cohen, C. Ratledge (Eds.).