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Volumn 1, Issue 1, 2006, Pages

An NF-κB and slug regulatory loop active in early vertebrate mesoderm

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MORPHOLINE; PROTEIN BCL X; PROTEIN REL2; PROTEIN REL3; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; ANTISENSE OLIGODEOXYNUCLEOTIDE; BCL XL PROTEIN, XENOPUS; BCL-XL PROTEIN, XENOPUS; PRIMER DNA; PROTEIN BCL 2; SNAIL FAMILY TRANSCRIPTION FACTORS; XENOPUS PROTEIN;

EID: 34447339841     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000106     Document Type: Article
Times cited : (40)

References (143)
  • 1
    • 33244463813 scopus 로고    scopus 로고
    • Complex network epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP (2006) Complex network epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7: 131-42.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 2
    • 12744251650 scopus 로고    scopus 로고
    • Analysis of forkhead and snail expression reveals epithelial-mesenchymal transitions during embryonic and larval development of Nematostella vectensis
    • Fritzenwanker JH, Saina M, Technau U (2004) Analysis of forkhead and snail expression reveals epithelial-mesenchymal transitions during embryonic and larval development of Nematostella vectensis. Dev Biol 275: 389-402.
    • (2004) Dev Biol , vol.275 , pp. 389-402
    • Fritzenwanker, J.H.1    Saina, M.2    Technau, U.3
  • 3
    • 1642430626 scopus 로고    scopus 로고
    • Origin and evolution of endoderm and mesoderm
    • Technau U, Scholz CB (2003) Origin and evolution of endoderm and mesoderm. Int J Dev Biol 47: 531-9.
    • (2003) Int J Dev Biol , vol.47 , pp. 531-539
    • Technau, U.1    Scholz, C.B.2
  • 5
    • 0026577840 scopus 로고
    • The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes
    • Whiteley M, Noguchi PD, Sensabaugh SM, Odenwald WF, Kassis JA (1992) The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes. Mech Dev 36: 117-27.
    • (1992) Mech Dev , vol.36 , pp. 117-127
    • Whiteley, M.1    Noguchi, P.D.2    Sensabaugh, S.M.3    Odenwald, W.F.4    Kassis, J.A.5
  • 6
    • 0033571580 scopus 로고    scopus 로고
    • The mesoderm determinant snail collaborates with related zinc-finger proteins to control Drosophila neurogenesis
    • Ashraf SI, Hu X, Roote J, Ip YT (1999) The mesoderm determinant snail collaborates with related zinc-finger proteins to control Drosophila neurogenesis. EMBO J 18: 6426-38.
    • (1999) EMBO J , vol.18 , pp. 6426-6438
    • Ashraf, S.I.1    Hu, X.2    Roote, J.3    Ip, Y.T.4
  • 7
    • 0035794537 scopus 로고    scopus 로고
    • A family of snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions
    • Cai Y, Chia W, Yang X (2001) A family of snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions. EMBO J 20: 1704-14.
    • (2001) EMBO J , vol.20 , pp. 1704-1714
    • Cai, Y.1    Chia, W.2    Yang, X.3
  • 8
    • 0028856133 scopus 로고
    • scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neuronal development
    • Roark M, Sturtevant MA, Emery J, Vaessin H, Grell E, Bier E (1995) scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neuronal development. Genes Dev 9: 2384-98.
    • (1995) Genes Dev , vol.9 , pp. 2384-2398
    • Roark, M.1    Sturtevant, M.A.2    Emery, J.3    Vaessin, H.4    Grell, E.5    Bier, E.6
  • 9
    • 0035312996 scopus 로고    scopus 로고
    • The increasing complexity of the Snail gene superfamily in metazoan evolution
    • Manzanares M, Locascio A, Nieto MA (2001) The increasing complexity of the Snail gene superfamily in metazoan evolution. Trends Genet 17: 178-81.
    • (2001) Trends Genet , vol.17 , pp. 178-181
    • Manzanares, M.1    Locascio, A.2    Nieto, M.A.3
  • 10
    • 0036943844 scopus 로고    scopus 로고
    • Characterisation of two snail genes in the gastropod mollusc Patella vulgata. Implications for understanding the ancestral function of the snail-related genes in Bilateria
    • Lespinet O, Nederbragt AJ, Cassan M, Dictus WJ, van Loon AE, et al. (2002) Characterisation of two snail genes in the gastropod mollusc Patella vulgata. Implications for understanding the ancestral function of the snail-related genes in Bilateria. Dev Genes Evol 212: 186-95.
    • (2002) Dev Genes Evol , vol.212 , pp. 186-195
    • Lespinet, O.1    Nederbragt, A.J.2    Cassan, M.3    Dictus, W.J.4    van Loon, A.E.5
  • 11
    • 0021220312 scopus 로고
    • Mutations and chromosomal rearrangements affecting the expression of Snail, a gene involved in embryonic patterning in Drosophila melanogaster
    • Grau Y, Carteret C, Simpson P (1984) Mutations and chromosomal rearrangements affecting the expression of Snail, a gene involved in embryonic patterning in Drosophila melanogaster. Genetics 108: 347-360.
    • (1984) Genetics , vol.108 , pp. 347-360
    • Grau, Y.1    Carteret, C.2    Simpson, P.3
  • 12
    • 0021034649 scopus 로고
    • Maternal-zygotic gene interactions during formation of the dorsoventral patternin in Drosophila embryos
    • Simpson P (1983) Maternal-zygotic gene interactions during formation of the dorsoventral patternin in Drosophila embryos. Genetics 105: 615-632.
    • (1983) Genetics , vol.105 , pp. 615-632
    • Simpson, P.1
  • 13
    • 0008125299 scopus 로고
    • Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome
    • Nusslein-Volhard C, Wieschaus E, Kluding H (1984) Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome. Roux's Arch Dev Biol 193: 267-282.
    • (1984) Roux's Arch Dev Biol , vol.193 , pp. 267-282
    • Nusslein-Volhard, C.1    Wieschaus, E.2    Kluding, H.3
  • 14
    • 0035167812 scopus 로고    scopus 로고
    • The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition
    • Carver EA, Jiang R, Lan Y, Oram KF, Gridley T (2001) The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol 21: 8184-8.
    • (2001) Mol Cell Biol , vol.21 , pp. 8184-8188
    • Carver, E.A.1    Jiang, R.2    Lan, Y.3    Oram, K.F.4    Gridley, T.5
  • 15
    • 0032525997 scopus 로고    scopus 로고
    • The Slug gene is not essential for mesoderm or neural crest development in mice
    • Jiang R, Lan Y, Norton CR, Sundberg JP, Gridley T (1998) The Slug gene is not essential for mesoderm or neural crest development in mice. Dev Biol 198: 277-85.
    • (1998) Dev Biol , vol.198 , pp. 277-285
    • Jiang, R.1    Lan, Y.2    Norton, C.R.3    Sundberg, J.P.4    Gridley, T.5
  • 16
    • 33745888092 scopus 로고    scopus 로고
    • Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice
    • Murray SA, Gridley T (2006) Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice. Proc Natl Acad Sci U S A 103: 10300-4.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 10300-10304
    • Murray, S.A.1    Gridley, T.2
  • 18
    • 0037103359 scopus 로고    scopus 로고
    • Zinc-finger transcription factor Slug contributes to the function of the stem cell factor c-kit signaling pathway
    • Perez-Losada J, Sanchez-Martin M, Rodriguez-Garcia A, Sanchez ML, Orfao A, et al. (2002) Zinc-finger transcription factor Slug contributes to the function of the stem cell factor c-kit signaling pathway. Blood 100: 1274-86.
    • (2002) Blood , vol.100 , pp. 1274-1286
    • Perez-Losada, J.1    Sanchez-Martin, M.2    Rodriguez-Garcia, A.3    Sanchez, M.L.4    Orfao, A.5
  • 19
    • 12944260524 scopus 로고    scopus 로고
    • Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes
    • Savagner P, Kusewitt DF, Carver EA, Magnino F, Choi C, et al. (2005) Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes. J Cell Physiol 202: 858-66.
    • (2005) J Cell Physiol , vol.202 , pp. 858-866
    • Savagner, P.1    Kusewitt, D.F.2    Carver, E.A.3    Magnino, F.4    Choi, C.5
  • 20
    • 0028318730 scopus 로고
    • Control of cell behavior during vertebrate development by Slug, a zinc finger gene
    • Nieto MA, Sargent MG, Wilkinson DG, Cooke J (1994) Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science 264: 835-9.
    • (1994) Science , vol.264 , pp. 835-839
    • Nieto, M.A.1    Sargent, M.G.2    Wilkinson, D.G.3    Cooke, J.4
  • 21
    • 0342409273 scopus 로고    scopus 로고
    • A novel function for the Xslug gene: Control of dorsal mesendoderm development by repressing BMP-4
    • Mayor R, Guerrero N, Young RM, Gomez-Skarmeta JL, Cuellar C (2000) A novel function for the Xslug gene: control of dorsal mesendoderm development by repressing BMP-4. Mech Dev 97: 47-56.
    • (2000) Mech Dev , vol.97 , pp. 47-56
    • Mayor, R.1    Guerrero, N.2    Young, R.M.3    Gomez-Skarmeta, J.L.4    Cuellar, C.5
  • 22
    • 0033198463 scopus 로고    scopus 로고
    • Inhibition of Neural Crest Migration in Xenopus Using Antisense Slug RNA
    • Carl TF, Dufton C, Hanken J, Klymkowsky MW (1999) Inhibition of Neural Crest Migration in Xenopus Using Antisense Slug RNA. Dev Biol 213: 101-115.
    • (1999) Dev Biol , vol.213 , pp. 101-115
    • Carl, T.F.1    Dufton, C.2    Hanken, J.3    Klymkowsky, M.W.4
  • 23
    • 0037326619 scopus 로고    scopus 로고
    • Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest
    • Aybar MJ, Nieto MA, Mayor R (2003) Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest. Development 130: 483-94.
    • (2003) Development , vol.130 , pp. 483-494
    • Aybar, M.J.1    Nieto, M.A.2    Mayor, R.3
  • 24
    • 0034193218 scopus 로고    scopus 로고
    • Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration
    • LaBonne C, Bronner-Fraser M (2000) Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migration. Dev Biol 221: 195-205.
    • (2000) Dev Biol , vol.221 , pp. 195-205
    • LaBonne, C.1    Bronner-Fraser, M.2
  • 25
    • 0031668376 scopus 로고    scopus 로고
    • Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo
    • Sefton M, Sanchez S, Nieto MA (1998) Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo. Development 125: 3111-21.
    • (1998) Development , vol.125 , pp. 3111-3121
    • Sefton, M.1    Sanchez, S.2    Nieto, M.A.3
  • 26
    • 0037168522 scopus 로고    scopus 로고
    • Modularity and reshuffling of Snail and Slug expression during vertebrate evolution
    • Locascio A, Manzanares M, Blanco MJ, Nieto MA (2002) Modularity and reshuffling of Snail and Slug expression during vertebrate evolution. Proc Natl Acad Sci USA 99: 16841-6.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16841-16846
    • Locascio, A.1    Manzanares, M.2    Blanco, M.J.3    Nieto, M.A.4
  • 27
    • 33646137784 scopus 로고    scopus 로고
    • Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development
    • Sakai D, Suzuki T, Osumi N, Wakamatsu Y (2006) Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development. Development 133: 1323-33.
    • (2006) Development , vol.133 , pp. 1323-1333
    • Sakai, D.1    Suzuki, T.2    Osumi, N.3    Wakamatsu, Y.4
  • 28
    • 0034680368 scopus 로고    scopus 로고
    • Snail/Slug family of repressors: Slowly going into the fast lane of development and cancer
    • Hemavathy K, Ashraf SI, Ip YT (2000) Snail/Slug family of repressors: slowly going into the fast lane of development and cancer. Gene 257: 1-12.
    • (2000) Gene , vol.257 , pp. 1-12
    • Hemavathy, K.1    Ashraf, S.I.2    Ip, Y.T.3
  • 29
    • 0027511507 scopus 로고
    • Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen
    • Jiang J, Levine M (1993) Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen. Cell 72: 741-52.
    • (1993) Cell , vol.72 , pp. 741-752
    • Jiang, J.1    Levine, M.2
  • 30
    • 0041827179 scopus 로고    scopus 로고
    • The Snail-like CES-1 protein of C. elegans can block the expression of the BH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins
    • Thellmann M, Hatzold J, Conradt B (2003) The Snail-like CES-1 protein of C. elegans can block the expression of the BH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins. Development 130: 4057-71.
    • (2003) Development , vol.130 , pp. 4057-4071
    • Thellmann, M.1    Hatzold, J.2    Conradt, B.3
  • 32
    • 0031005659 scopus 로고    scopus 로고
    • The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition
    • Savagner P, Yamada KM, Thiery JP (1997) The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J Cell Biol 137: 1403-19.
    • (1997) J Cell Biol , vol.137 , pp. 1403-1419
    • Savagner, P.1    Yamada, K.M.2    Thiery, J.P.3
  • 33
    • 15544362735 scopus 로고    scopus 로고
    • Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level
    • Kurrey NK, Amit K, Bapat SA (2005) Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level. Gynecol Oncol 97: 155-65.
    • (2005) Gynecol Oncol , vol.97 , pp. 155-165
    • Kurrey, N.K.1    Amit, K.2    Bapat, S.A.3
  • 34
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A, Perez MM, Rodrigo I, Locascio A, Blanco MJ, et al. (2000) The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2: 76-83.
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez, M.M.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5
  • 36
    • 0035816677 scopus 로고    scopus 로고
    • Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail
    • Poser I, Dominguez D, de Herreros AG, Varnai A, Buettner R, et al. (2001) Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail. J Biol Chem 276: 24661-6.
    • (2001) J Biol Chem , vol.276 , pp. 24661-24666
    • Poser, I.1    Dominguez, D.2    de Herreros, A.G.3    Varnai, A.4    Buettner, R.5
  • 37
    • 0038106228 scopus 로고    scopus 로고
    • Regulation of tight junctions during the epithelium-mesenchyme transition: Direct repression of the gene expression of claudins/occludin by Snail
    • Ikenouchi J, Matsuda M, Furuse M, Tsukita S (2003) Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail. J Cell Sci 116: 1959-67.
    • (2003) J Cell Sci , vol.116 , pp. 1959-1967
    • Ikenouchi, J.1    Matsuda, M.2    Furuse, M.3    Tsukita, S.4
  • 38
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • Bolos V, Peinado H, Perez-Moreno MA, Fraga MF, Esteller M, et al. (2003) The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci 116: 499-511.
    • (2003) J Cell Sci , vol.116 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5
  • 39
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-cadherin in breast cancer
    • Hajra KM, Chen DY, Fearon ER (2002) The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res 62: 1613-8.
    • (2002) Cancer Res , vol.62 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.2    Fearon, E.R.3
  • 40
    • 0033197540 scopus 로고    scopus 로고
    • The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein
    • Metzstein MM, Horvitz HR (1999) The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein. Mol Cell 4: 309-19.
    • (1999) Mol Cell , vol.4 , pp. 309-319
    • Metzstein, M.M.1    Horvitz, H.R.2
  • 41
    • 0033197879 scopus 로고    scopus 로고
    • SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
    • Inukai T, Inoue A, Kurosawa H, Goi K, Shinjyo T, et al. (1999) SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol Cell 4: 343-52.
    • (1999) Mol Cell , vol.4 , pp. 343-352
    • Inukai, T.1    Inoue, A.2    Kurosawa, H.3    Goi, K.4    Shinjyo, T.5
  • 42
    • 19044372843 scopus 로고    scopus 로고
    • Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo
    • Inoue A, Seidel MG, Wu W, Kamizono S, Ferrando AA, et al. (2002) Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo. Cancer Cell 2: 279-88.
    • (2002) Cancer Cell , vol.2 , pp. 279-288
    • Inoue, A.1    Seidel, M.G.2    Wu, W.3    Kamizono, S.4    Ferrando, A.A.5
  • 43
    • 4344662447 scopus 로고    scopus 로고
    • Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress
    • Kajita M, McClinic KN, Wade PA (2004) Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress. Mol Cell Biol 24: 7559-66.
    • (2004) Mol Cell Biol , vol.24 , pp. 7559-7566
    • Kajita, M.1    McClinic, K.N.2    Wade, P.A.3
  • 45
    • 27744547091 scopus 로고    scopus 로고
    • Slug Antagonizes p53-Mediated Apoptosis of Hematopoietic Progenitors by Repressing puma
    • Wu WS, Heinrichs S, Xu D, Garrison SP, Zambetti GP, et al. (2005) Slug Antagonizes p53-Mediated Apoptosis of Hematopoietic Progenitors by Repressing puma. Cell 123: 641-53.
    • (2005) Cell , vol.123 , pp. 641-653
    • Wu, W.S.1    Heinrichs, S.2    Xu, D.3    Garrison, S.P.4    Zambetti, G.P.5
  • 46
    • 25844508786 scopus 로고    scopus 로고
    • The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
    • Gupta PB, Kuperwasser C, Brunet JP, Ramaswamy S, Kuo WL, et al. (2005) The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet 37: 1047-54.
    • (2005) Nat Genet , vol.37 , pp. 1047-1054
    • Gupta, P.B.1    Kuperwasser, C.2    Brunet, J.P.3    Ramaswamy, S.4    Kuo, W.L.5
  • 47
    • 28144456743 scopus 로고    scopus 로고
    • Transcription repressor slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma
    • Shih JY, Tsai MF, Chang TH, Chang YL, Yuan A, et al. (2005) Transcription repressor slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma. Clin Cancer Res 11: 8070-8.
    • (2005) Clin Cancer Res , vol.11 , pp. 8070-8078
    • Shih, J.Y.1    Tsai, M.F.2    Chang, T.H.3    Chang, Y.L.4    Yuan, A.5
  • 48
    • 4444311406 scopus 로고    scopus 로고
    • Roles of the transcription factors snail and slug during mammary morphogenesis and breast carcinoma progression
    • Come C, Arnoux V, Bibeau F, Savagner P (2004) Roles of the transcription factors snail and slug during mammary morphogenesis and breast carcinoma progression. J Mammary Gland Biol Neoplasia 9: 183-93.
    • (2004) J Mammary Gland Biol Neoplasia , vol.9 , pp. 183-193
    • Come, C.1    Arnoux, V.2    Bibeau, F.3    Savagner, P.4
  • 50
    • 23844528776 scopus 로고    scopus 로고
    • The Snail genes as inducers of cell movement and survival: Implications in development and cancer
    • Barrallo-Gimeno A, Nieto MA (2005) The Snail genes as inducers of cell movement and survival: implications in development and cancer. Development 132: 3151-61.
    • (2005) Development , vol.132 , pp. 3151-3161
    • Barrallo-Gimeno, A.1    Nieto, M.A.2
  • 51
    • 0036333522 scopus 로고    scopus 로고
    • Overexpression of Snail family members highlights their ability to promote chick neural crest formation
    • del Barrio MG, Nieto MA (2002) Overexpression of Snail family members highlights their ability to promote chick neural crest formation. Development 129: 1583-93.
    • (2002) Development , vol.129 , pp. 1583-1593
    • del Barrio, M.G.1    Nieto, M.A.2
  • 52
    • 13344259902 scopus 로고    scopus 로고
    • The transcriptional control of trunk neural crest induction, survival, and delamination
    • Cheung M, Chaboissier MC, Mynett A, Hirst E, Schedl A, et al. (2005) The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell 8: 179-92.
    • (2005) Dev Cell , vol.8 , pp. 179-192
    • Cheung, M.1    Chaboissier, M.C.2    Mynett, A.3    Hirst, E.4    Schedl, A.5
  • 53
    • 1942425459 scopus 로고    scopus 로고
    • The repressor function of snail is required for Drosophila gastrulation and is not replaceable by Escargot or Worniu
    • Hemavathy K, Hu X, Ashraf SI, Small SJ, Ip YT (2004) The repressor function of snail is required for Drosophila gastrulation and is not replaceable by Escargot or Worniu. Dev Biol 269: 411-20.
    • (2004) Dev Biol , vol.269 , pp. 411-420
    • Hemavathy, K.1    Hu, X.2    Ashraf, S.I.3    Small, S.J.4    Ip, Y.T.5
  • 54
    • 8744305031 scopus 로고    scopus 로고
    • Induction of stem cell factor/c-Kit/slug signal transduction in multidrug-resistant malignant mesothelioma cells
    • Catalano A, Rodilossi S, Rippo MR, Caprari P, Procopio A (2004) Induction of stem cell factor/c-Kit/slug signal transduction in multidrug-resistant malignant mesothelioma cells. J Biol Chem 279: 46706-14.
    • (2004) J Biol Chem , vol.279 , pp. 46706-46714
    • Catalano, A.1    Rodilossi, S.2    Rippo, M.R.3    Caprari, P.4    Procopio, A.5
  • 55
    • 33750358078 scopus 로고    scopus 로고
    • Genetic profiling of epithelial cells expressing e-cadherin repressors reveals a distinct role for snail, slug, and e47 factors in epithelial-mesenchymal transition
    • Moreno-Bueno G, Cubillo E, Sarrio D, Peinado H, Rodriguez-Pinilla SM, et al. (2006) Genetic profiling of epithelial cells expressing e-cadherin repressors reveals a distinct role for snail, slug, and e47 factors in epithelial-mesenchymal transition. Cancer Res 66: 9543-56.
    • (2006) Cancer Res , vol.66 , pp. 9543-9556
    • Moreno-Bueno, G.1    Cubillo, E.2    Sarrio, D.3    Peinado, H.4    Rodriguez-Pinilla, S.M.5
  • 56
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • Zhou BP, Deng J, Xia W, Xu J, Li YM, et al. (2004) Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol 6: 931-40.
    • (2004) Nat Cell Biol , vol.6 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5
  • 57
    • 15744374449 scopus 로고    scopus 로고
    • Wnt-dependent regulation of the E-cadherin repressor snail
    • Yook JI, Li XY, Ota I, Fearon ER, Weiss SJ (2005) Wnt-dependent regulation of the E-cadherin repressor snail. J Biol Chem 280: 11740-8.
    • (2005) J Biol Chem , vol.280 , pp. 11740-11748
    • Yook, J.I.1    Li, X.Y.2    Ota, I.3    Fearon, E.R.4    Weiss, S.J.5
  • 58
    • 16844377441 scopus 로고    scopus 로고
    • Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions
    • Yang Z, Rayala S, Nguyen D, Vadlamudi RK, Chen S, et al. (2005) Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions. Cancer Res 65: 3179-84.
    • (2005) Cancer Res , vol.65 , pp. 3179-3184
    • Yang, Z.1    Rayala, S.2    Nguyen, D.3    Vadlamudi, R.K.4    Chen, S.5
  • 59
    • 0038450250 scopus 로고    scopus 로고
    • Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor
    • Dominguez D, Montserrat-Sentis B, Virgos-Soler A, Guaita S, Grueso J, et al. (2003) Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor. Mol Cell Biol 23: 5078-89.
    • (2003) Mol Cell Biol , vol.23 , pp. 5078-5089
    • Dominguez, D.1    Montserrat-Sentis, B.2    Virgos-Soler, A.3    Guaita, S.4    Grueso, J.5
  • 60
    • 33749391866 scopus 로고    scopus 로고
    • Vernon AE, LaBonne C (2006) Slug stability is dynamically regulated during neural crest development by the F-box protein Ppa. Development 133: 3359-70.
    • Vernon AE, LaBonne C (2006) Slug stability is dynamically regulated during neural crest development by the F-box protein Ppa. Development 133: 3359-70.
  • 61
    • 14244260205 scopus 로고    scopus 로고
    • A balance between the anti-apoptotic activity of Slug and the apoptotic activity of msx1 is required for the proper development of the neural crest
    • Tribulo C, Aybar MJ, Sanchez SS, Mayor R (2004) A balance between the anti-apoptotic activity of Slug and the apoptotic activity of msx1 is required for the proper development of the neural crest. Dev Biol 275: 325-42.
    • (2004) Dev Biol , vol.275 , pp. 325-342
    • Tribulo, C.1    Aybar, M.J.2    Sanchez, S.S.3    Mayor, R.4
  • 62
    • 0032608362 scopus 로고    scopus 로고
    • Development of neural crest in Xenopus
    • Mayor R, Young R, Vargas A (1999) Development of neural crest in Xenopus. Curr Top Dev Biol 43: 85-113.
    • (1999) Curr Top Dev Biol , vol.43 , pp. 85-113
    • Mayor, R.1    Young, R.2    Vargas, A.3
  • 63
    • 0035839534 scopus 로고    scopus 로고
    • Cloning and characterization of three Xenopus Slug promoters reveal direct regulation by Lef/beta-catenin signaling
    • Vallin J, Thuret R, Giacomello E, Faraldo MM, Thiery JP, et al. (2001) Cloning and characterization of three Xenopus Slug promoters reveal direct regulation by Lef/beta-catenin signaling. J Biol Chem 287: 30350-8.
    • (2001) J Biol Chem , vol.287 , pp. 30350-30358
    • Vallin, J.1    Thuret, R.2    Giacomello, E.3    Faraldo, M.M.4    Thiery, J.P.5
  • 66
    • 0027375874 scopus 로고
    • Basic fibroblast growth factor induces differentiation of neural tube and neural crest lineages of cultured ectoderm cells from Xenopus gastrula
    • Kengaku M, Okamoto H (1993) Basic fibroblast growth factor induces differentiation of neural tube and neural crest lineages of cultured ectoderm cells from Xenopus gastrula. Development 119: 1067-78.
    • (1993) Development , vol.119 , pp. 1067-1078
    • Kengaku, M.1    Okamoto, H.2
  • 67
    • 0031406026 scopus 로고    scopus 로고
    • The origins of the neural crest. Part I: Embryonic induction
    • Baker CV, Bronner-Fraser M (1997) The origins of the neural crest. Part I: embryonic induction. Mech Dev 69: 3-11.
    • (1997) Mech Dev , vol.69 , pp. 3-11
    • Baker, C.V.1    Bronner-Fraser, M.2
  • 68
    • 0032518332 scopus 로고    scopus 로고
    • Paraxial-fated mesoderm is required for neural crest induction in Xenopus embryos
    • Bonstein L, Elias S, Frank D (1998) Paraxial-fated mesoderm is required for neural crest induction in Xenopus embryos. Dev Biol 193: 156-68.
    • (1998) Dev Biol , vol.193 , pp. 156-168
    • Bonstein, L.1    Elias, S.2    Frank, D.3
  • 69
    • 0041669583 scopus 로고    scopus 로고
    • Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals
    • Monsoro-Burq AH, Fletcher RB, Harland RM (2003) Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals. Development 130: 3111-24.
    • (2003) Development , vol.130 , pp. 3111-3124
    • Monsoro-Burq, A.H.1    Fletcher, R.B.2    Harland, R.M.3
  • 70
    • 0028949489 scopus 로고
    • Induction of the prospective neural crest of Xenopus
    • Mayor R, Morgan R, Sargent MG (1995) Induction of the prospective neural crest of Xenopus. Development 121: 767-77.
    • (1995) Development , vol.121 , pp. 767-777
    • Mayor, R.1    Morgan, R.2    Sargent, M.G.3
  • 71
    • 0028788846 scopus 로고
    • Efficient hormone-inducible protein function in Xenopus laevis
    • Kolm PJ, Sive HL (1995) Efficient hormone-inducible protein function in Xenopus laevis. Dev Biol 171: 267-72.
    • (1995) Dev Biol , vol.171 , pp. 267-272
    • Kolm, P.J.1    Sive, H.L.2
  • 73
    • 0032508486 scopus 로고    scopus 로고
    • Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha
    • de Moissac D, Mustapha S, Greenberg AH, Kirshenbaum LA (1998) Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha. J Biol Chem 273: 23946-51.
    • (1998) J Biol Chem , vol.273 , pp. 23946-23951
    • de Moissac, D.1    Mustapha, S.2    Greenberg, A.H.3    Kirshenbaum, L.A.4
  • 74
    • 0033748413 scopus 로고    scopus 로고
    • Bcl-2 intersects the NFkappaB signalling pathway and suppresses apoptosis in ventricular myocytes
    • Kirshenbaum LA (2000) Bcl-2 intersects the NFkappaB signalling pathway and suppresses apoptosis in ventricular myocytes. Clin Invest Med 23: 322-30.
    • (2000) Clin Invest Med , vol.23 , pp. 322-330
    • Kirshenbaum, L.A.1
  • 75
    • 0037064129 scopus 로고    scopus 로고
    • IKK beta is required for Bcl-2-mediated NF-kappa B activation in ventricular myocytes
    • Regula KM, Ens K, Kirshenbaum LA (2002) IKK beta is required for Bcl-2-mediated NF-kappa B activation in ventricular myocytes. J Biol Chem 277: 38676-82.
    • (2002) J Biol Chem , vol.277 , pp. 38676-38682
    • Regula, K.M.1    Ens, K.2    Kirshenbaum, L.A.3
  • 76
    • 6044277953 scopus 로고    scopus 로고
    • Human Bcl-2 activates ERK signaling pathway to regulate activating protein-1, lens epithelium-derived growth factor and downstream genes
    • Feng H, Xiang H, Mao YW, Wang J, Liu JP, et al. (2004) Human Bcl-2 activates ERK signaling pathway to regulate activating protein-1, lens epithelium-derived growth factor and downstream genes. Oncogene 23: 7310-21.
    • (2004) Oncogene , vol.23 , pp. 7310-7321
    • Feng, H.1    Xiang, H.2    Mao, Y.W.3    Wang, J.4    Liu, J.P.5
  • 77
    • 1342325424 scopus 로고    scopus 로고
    • bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation: Involvement of ERK1/ERK2 activity
    • Trisciuoglio D, Iervolino A, Candiloro A, Fibbi G, Fanciulli M, et al. (2004) bcl-2 induction of urokinase plasminogen activator receptor expression in human cancer cells through Sp1 activation: involvement of ERK1/ERK2 activity. J Biol Chem 279: 6737-45.
    • (2004) J Biol Chem , vol.279 , pp. 6737-6745
    • Trisciuoglio, D.1    Iervolino, A.2    Candiloro, A.3    Fibbi, G.4    Fanciulli, M.5
  • 78
    • 0028929371 scopus 로고
    • Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation
    • Brockman JA, Scherer DC, McKinsey TA, Hall SM, Qi X, et al. (1995) Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation. Mol Cell Biol 15: 2809-18.
    • (1995) Mol Cell Biol , vol.15 , pp. 2809-2818
    • Brockman, J.A.1    Scherer, D.C.2    McKinsey, T.A.3    Hall, S.M.4    Qi, X.5
  • 79
    • 14044268207 scopus 로고    scopus 로고
    • Inhibition of IkappaB kinase activity by acetyl-boswellic acids promotes apoptosis in androgen-independent PC-3 prostate cancer cells in vitro and in vivo
    • Syrovets T, Gschwend JE, Buchele B, Laumonnier Y, Zugmaier W, et al. (2005) Inhibition of IkappaB kinase activity by acetyl-boswellic acids promotes apoptosis in androgen-independent PC-3 prostate cancer cells in vitro and in vivo. J Biol Chem 280: 6170-80.
    • (2005) J Biol Chem , vol.280 , pp. 6170-6180
    • Syrovets, T.1    Gschwend, J.E.2    Buchele, B.3    Laumonnier, Y.4    Zugmaier, W.5
  • 80
    • 10844262511 scopus 로고    scopus 로고
    • Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-alpha induction in monocytes by direct interaction with IkappaB kinases
    • Syrovets T, Buchele B, Krauss C, Laumonnier Y, Simmet T (2005) Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-alpha induction in monocytes by direct interaction with IkappaB kinases. J Immunol 174: 498-506.
    • (2005) J Immunol , vol.174 , pp. 498-506
    • Syrovets, T.1    Buchele, B.2    Krauss, C.3    Laumonnier, Y.4    Simmet, T.5
  • 81
    • 33644536397 scopus 로고    scopus 로고
    • Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression
    • Takada Y, Ichikawa H, Badmaev V, Aggarwal BB (2006) Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression. J Immunol 176: 3127-40.
    • (2006) J Immunol , vol.176 , pp. 3127-3140
    • Takada, Y.1    Ichikawa, H.2    Badmaev, V.3    Aggarwal, B.B.4
  • 82
    • 0025771962 scopus 로고
    • Expression of a mRNA related to c-rel and dorsal in early Xenopus laevis embryos
    • Kao KR, Hopwood ND (1991) Expression of a mRNA related to c-rel and dorsal in early Xenopus laevis embryos. Proc Natl Acad Sci USA 88: 2697-701.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2697-2701
    • Kao, K.R.1    Hopwood, N.D.2
  • 83
    • 0028008549 scopus 로고
    • XrelA, a Xenopus maternal and zygotic homologue of the p65 subunit of NF-kappa B. Characterisation of transcriptional properties in the developing embryo and identification of a negative interference mutant
    • Richardson JC, Garcia EA, Woodland HR (1994) XrelA, a Xenopus maternal and zygotic homologue of the p65 subunit of NF-kappa B. Characterisation of transcriptional properties in the developing embryo and identification of a negative interference mutant. Mech Dev 45: 173-89.
    • (1994) Mech Dev , vol.45 , pp. 173-189
    • Richardson, J.C.1    Garcia, E.A.2    Woodland, H.R.3
  • 84
    • 0028786257 scopus 로고
    • Control of axis formation in Xenopus by the NF-kappa B-I kappa B system
    • Tannahill D, Wardle FC (1995) Control of axis formation in Xenopus by the NF-kappa B-I kappa B system. Int J Dev Biol 39: 549-58.
    • (1995) Int J Dev Biol , vol.39 , pp. 549-558
    • Tannahill, D.1    Wardle, F.C.2
  • 85
    • 0035146292 scopus 로고    scopus 로고
    • Xrel3 is required for head development in Xenopus laevis
    • Lake BB, Ford R, Kao KR (2001) Xrel3 is required for head development in Xenopus laevis. Development 128: 263-73.
    • (2001) Development , vol.128 , pp. 263-273
    • Lake, B.B.1    Ford, R.2    Kao, K.R.3
  • 86
    • 0028865575 scopus 로고
    • Molecular cloning of cDNA encoding the Xenopus homolog of mammalian RelB
    • Suzuki K, Yamamoto T, Inoue J (1995) Molecular cloning of cDNA encoding the Xenopus homolog of mammalian RelB. Nucleic Acids Res 23: 4664-9.
    • (1995) Nucleic Acids Res , vol.23 , pp. 4664-4669
    • Suzuki, K.1    Yamamoto, T.2    Inoue, J.3
  • 87
    • 0032484689 scopus 로고    scopus 로고
    • Identification and expression of the Xenopus homolog of mammalian p100-NFkappaB2
    • Suzuki K, Tsuchida J, Yamamoto T, Inoue J (1998) Identification and expression of the Xenopus homolog of mammalian p100-NFkappaB2. Gene 206: 1-9.
    • (1998) Gene , vol.206 , pp. 1-9
    • Suzuki, K.1    Tsuchida, J.2    Yamamoto, T.3    Inoue, J.4
  • 88
    • 0029038507 scopus 로고
    • Cloning, characterization and expression of two Xenopus bcl-2-like cell-survival genes
    • Cruz-Reyes J, Tata JR (1995) Cloning, characterization and expression of two Xenopus bcl-2-like cell-survival genes. Gene 158: 171-9.
    • (1995) Gene , vol.158 , pp. 171-179
    • Cruz-Reyes, J.1    Tata, J.R.2
  • 89
    • 0031602486 scopus 로고    scopus 로고
    • Involvement of NF-kappaB associated proteins in FGF-mediated mesoderm induction
    • Beck CW, Sutherland DJ, Woodland HR (1998) Involvement of NF-kappaB associated proteins in FGF-mediated mesoderm induction. Int J Dev Biol 42: 67-77.
    • (1998) Int J Dev Biol , vol.42 , pp. 67-77
    • Beck, C.W.1    Sutherland, D.J.2    Woodland, H.R.3
  • 90
    • 24344471404 scopus 로고    scopus 로고
    • Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail network in the gastrulating embryo
    • Ganguly A, Jiang J, Ip YT (2005) Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail network in the gastrulating embryo. Development 132: 3419-29.
    • (2005) Development , vol.132 , pp. 3419-3429
    • Ganguly, A.1    Jiang, J.2    Ip, Y.T.3
  • 91
    • 26944485185 scopus 로고    scopus 로고
    • WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity
    • Gordon MD, Dionne MS, Schneider DS, Nusse R (2005) WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity. Nature 437: 746-9.
    • (2005) Nature , vol.437 , pp. 746-749
    • Gordon, M.D.1    Dionne, M.S.2    Schneider, D.S.3    Nusse, R.4
  • 92
    • 0033728564 scopus 로고    scopus 로고
    • A novel member of the Xenopus Zic family, Zic5, mediates neural crest development
    • Nakata K, Koyabu Y, Aruga J, Mikoshiba K (2000) A novel member of the Xenopus Zic family, Zic5, mediates neural crest development. Mech Dev 99: 83-91.
    • (2000) Mech Dev , vol.99 , pp. 83-91
    • Nakata, K.1    Koyabu, Y.2    Aruga, J.3    Mikoshiba, K.4
  • 93
    • 4544378019 scopus 로고    scopus 로고
    • Gene-regulatory interactions in neural crest evolution and development
    • Meulemans D, Bronner-Fraser M (2004) Gene-regulatory interactions in neural crest evolution and development. Dev Cell 7: 291-9.
    • (2004) Dev Cell , vol.7 , pp. 291-299
    • Meulemans, D.1    Bronner-Fraser, M.2
  • 94
    • 8844287717 scopus 로고    scopus 로고
    • Involvement of caspase-9 in execution of the maternal program of apoptosis in Xenopus late blastulae overexpressed with S-adenosylmethionine decarboxylase
    • Takayama E, Higo T, Kai M, Fukasawa M, Nakajima K, et al. (2004) Involvement of caspase-9 in execution of the maternal program of apoptosis in Xenopus late blastulae overexpressed with S-adenosylmethionine decarboxylase. Biochem Biophys Res Commun 325: 1367-75.
    • (2004) Biochem Biophys Res Commun , vol.325 , pp. 1367-1375
    • Takayama, E.1    Higo, T.2    Kai, M.3    Fukasawa, M.4    Nakajima, K.5
  • 95
    • 0032848297 scopus 로고    scopus 로고
    • Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis
    • de Moissac D, Zheng H, Kirshenbaum LA (1999) Linkage of the BH4 domain of Bcl-2 and the nuclear factor kappaB signaling pathway for suppression of apoptosis. J Biol Chem 274: 29505-9.
    • (1999) J Biol Chem , vol.274 , pp. 29505-29509
    • de Moissac, D.1    Zheng, H.2    Kirshenbaum, L.A.3
  • 96
    • 0028999873 scopus 로고
    • bcl-2 overexpression inhibits cell death and promotes the morphogenesis, but not tumorigenesis of human mammary epithelial cells
    • Lu PJ, Lu QL, Rughetti A, Taylor-Papadimitriou J (1995) bcl-2 overexpression inhibits cell death and promotes the morphogenesis, but not tumorigenesis of human mammary epithelial cells. J Cell Biol 129: 1363-78.
    • (1995) J Cell Biol , vol.129 , pp. 1363-1378
    • Lu, P.J.1    Lu, Q.L.2    Rughetti, A.3    Taylor-Papadimitriou, J.4
  • 97
    • 0141613761 scopus 로고    scopus 로고
    • Bcl-2 expression decreases cadherin-mediated cell-cell adhesion
    • Li L, Backer J, Wong AS, Schwanke EL, Stewart BG, et al. (2003) Bcl-2 expression decreases cadherin-mediated cell-cell adhesion. J Cell Sci 116: 3687-700.
    • (2003) J Cell Sci , vol.116 , pp. 3687-3700
    • Li, L.1    Backer, J.2    Wong, A.S.3    Schwanke, E.L.4    Stewart, B.G.5
  • 98
    • 4344612243 scopus 로고    scopus 로고
    • NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
    • Huber MA, Azoitei N, Baumann B, Grunert S, Sommer A, et al. (2004) NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest 114: 569-81.
    • (2004) J Clin Invest , vol.114 , pp. 569-581
    • Huber, M.A.1    Azoitei, N.2    Baumann, B.3    Grunert, S.4    Sommer, A.5
  • 99
    • 12144266241 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: Implications for the epithelial-mesenchymal transition
    • Bachelder RE, Yoon SO, Franci C, de Herreros AG, Mercurio AM (2005) Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition. J Cell Biol 168: 29-33.
    • (2005) J Cell Biol , vol.168 , pp. 29-33
    • Bachelder, R.E.1    Yoon, S.O.2    Franci, C.3    de Herreros, A.G.4    Mercurio, A.M.5
  • 100
    • 0026654687 scopus 로고
    • Individual dorsal morphogen binding sites mediate activation and repression in the Drosophila embryo
    • Jiang J, Rushlow CA, Zhou Q, Small S, Levine M (1992) Individual dorsal morphogen binding sites mediate activation and repression in the Drosophila embryo. EMBO J 11: 3147-54.
    • (1992) EMBO J , vol.11 , pp. 3147-3154
    • Jiang, J.1    Rushlow, C.A.2    Zhou, Q.3    Small, S.4    Levine, M.5
  • 101
    • 0141780826 scopus 로고    scopus 로고
    • NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism
    • Sitcheran R, Cogswell PC, Baldwin Jr AS (2003) NF-kappaB mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism. Genes Dev 17: 2368-73.
    • (2003) Genes Dev , vol.17 , pp. 2368-2373
    • Sitcheran, R.1    Cogswell, P.C.2    Baldwin Jr, A.S.3
  • 102
    • 0037043125 scopus 로고    scopus 로고
    • Rel/ NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer
    • Gilmore T, Gapuzan ME, Kalaitzidis D, Starczynowski D (2002) Rel/ NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer. Cancer Lett 181: 1-9.
    • (2002) Cancer Lett , vol.181 , pp. 1-9
    • Gilmore, T.1    Gapuzan, M.E.2    Kalaitzidis, D.3    Starczynowski, D.4
  • 104
    • 23244457362 scopus 로고    scopus 로고
    • Inflammation and cancer: When NF-kappaB amalgamates the perilous partnership
    • Dobrovolskaia MA, Kozlov SV (2005) Inflammation and cancer: when NF-kappaB amalgamates the perilous partnership. Curr Cancer Drug Targets 5: 325-44.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 325-344
    • Dobrovolskaia, M.A.1    Kozlov, S.V.2
  • 105
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M (2006) Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-6.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 106
    • 4644324186 scopus 로고    scopus 로고
    • NF-kappaB functions as a tumour promoter in inflammation-associated cancer
    • Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, et al. (2004) NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 431: 461-6.
    • (2004) Nature , vol.431 , pp. 461-466
    • Pikarsky, E.1    Porat, R.M.2    Stein, I.3    Abramovitch, R.4    Amit, S.5
  • 107
    • 0028179224 scopus 로고
    • NF-kappa B and I kappa B alpha: An inducible regulatory system in endothelial activation
    • Read MA, Whitley MZ, Williams AJ, Collins T (1994) NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation. J Exp Med 179: 503-12.
    • (1994) J Exp Med , vol.179 , pp. 503-512
    • Read, M.A.1    Whitley, M.Z.2    Williams, A.J.3    Collins, T.4
  • 108
    • 0028170124 scopus 로고
    • Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha
    • Ito CY, Kazantsev AG, Baldwin Jr AS (1994) Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha. Nucleic Acids Res 22: 3787-92.
    • (1994) Nucleic Acids Res , vol.22 , pp. 3787-3792
    • Ito, C.Y.1    Kazantsev, A.G.2    Baldwin Jr, A.S.3
  • 109
    • 0032827012 scopus 로고    scopus 로고
    • Induction of Bcl-x(L) expression by human T-cell leukemia virus type 1 Tax through NF-kappaB in apoptosis-resistant T-cell transfectants with Tax
    • Tsukahara T, Kannagi M, Ohashi T, Kato H, Arai M, Nunez G, et al. (1999) Induction of Bcl-x(L) expression by human T-cell leukemia virus type 1 Tax through NF-kappaB in apoptosis-resistant T-cell transfectants with Tax. J Virol 73: 7981-7.
    • (1999) J Virol , vol.73 , pp. 7981-7987
    • Tsukahara, T.1    Kannagi, M.2    Ohashi, T.3    Kato, H.4    Arai, M.5    Nunez, G.6
  • 110
    • 0034663779 scopus 로고    scopus 로고
    • The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD++ lymphocytes
    • Khoshnan A, Tindell C, Laux I, Bae D, Bennett B, et al. (2000) The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD++ lymphocytes. J Immunol 165: 1743-54.
    • (2000) J Immunol , vol.165 , pp. 1743-1754
    • Khoshnan, A.1    Tindell, C.2    Laux, I.3    Bae, D.4    Bennett, B.5
  • 111
    • 0034053965 scopus 로고    scopus 로고
    • Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation
    • Pise-Masison CA, Mahieux R, Jiang H, Ashcroft M, Radonovich M, et al. (2000) Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation. Mol Cell Biol 20: 3377-86.
    • (2000) Mol Cell Biol , vol.20 , pp. 3377-3386
    • Pise-Masison, C.A.1    Mahieux, R.2    Jiang, H.3    Ashcroft, M.4    Radonovich, M.5
  • 112
    • 1642553460 scopus 로고    scopus 로고
    • To be, or not to be: NF-kappaB is the answer-role of Rel/NF-kappaB in the regulation of apoptosis
    • Kucharczak J, Simmons MJ, Fan Y, Gelinas C (2003) To be, or not to be: NF-kappaB is the answer-role of Rel/NF-kappaB in the regulation of apoptosis. Oncogene 22: 8961-82.
    • (2003) Oncogene , vol.22 , pp. 8961-8982
    • Kucharczak, J.1    Simmons, M.J.2    Fan, Y.3    Gelinas, C.4
  • 113
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q, Verma IM (2002) NF-kappaB regulation in the immune system. Nat Rev Immunol 2: 725-34.
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 114
    • 28444472744 scopus 로고    scopus 로고
    • Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors
    • Gurova KV, Hill JE, Guo C, Prokvolit A, Burdelya LG, et al. (2005) Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-kappaB-dependent mechanism of p53 suppression in tumors. Proc Natl Acad Sci USA 102: 17448-53.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 17448-17453
    • Gurova, K.V.1    Hill, J.E.2    Guo, C.3    Prokvolit, A.4    Burdelya, L.G.5
  • 115
    • 0032954928 scopus 로고    scopus 로고
    • Transcriptional cross talk between NF-kappaB and p53
    • Webster GA, Perkins ND (1999) Transcriptional cross talk between NF-kappaB and p53. Mol Cell Biol 19: 3485-95.
    • (1999) Mol Cell Biol , vol.19 , pp. 3485-3495
    • Webster, G.A.1    Perkins, N.D.2
  • 116
    • 0035970102 scopus 로고    scopus 로고
    • The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage
    • Finkielstein CV, Lewellyn AL, Maller JL (2001) The midblastula transition in Xenopus embryos activates multiple pathways to prevent apoptosis in response to DNA damage. Proc Natl Acad Sci USA 98: 1006-11.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1006-1011
    • Finkielstein, C.V.1    Lewellyn, A.L.2    Maller, J.L.3
  • 117
    • 0030931607 scopus 로고    scopus 로고
    • Developmentally regulated activation of apoptosis early in Xenopus gastrulation results in cyclin A degradation during interphase of the cell cycle
    • Stack JH, Newport JW (1997) Developmentally regulated activation of apoptosis early in Xenopus gastrulation results in cyclin A degradation during interphase of the cell cycle. Development 124: 3185-95.
    • (1997) Development , vol.124 , pp. 3185-3195
    • Stack, J.H.1    Newport, J.W.2
  • 118
    • 0031405590 scopus 로고    scopus 로고
    • A developmental timer that regulates apoptosis at the onset of gastrulation
    • Hensey C, Gautier J (1997) A developmental timer that regulates apoptosis at the onset of gastrulation. Mech Dev 69: 183-95.
    • (1997) Mech Dev , vol.69 , pp. 183-195
    • Hensey, C.1    Gautier, J.2
  • 119
    • 7644223910 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis
    • Li L, Aggarwal BB, Shishodia S, Abbruzzese J, Kurzrock R (2004) Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. Cancer 101: 2351-62.
    • (2004) Cancer , vol.101 , pp. 2351-2362
    • Li, L.1    Aggarwal, B.B.2    Shishodia, S.3    Abbruzzese, J.4    Kurzrock, R.5
  • 120
    • 33645803418 scopus 로고    scopus 로고
    • Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B/p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions
    • Su CC, Chen GW, Lin JG, Wu LT, Chung JG (2006) Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B/p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions. Anticancer Res 26: 1281-8.
    • (2006) Anticancer Res , vol.26 , pp. 1281-1288
    • Su, C.C.1    Chen, G.W.2    Lin, J.G.3    Wu, L.T.4    Chung, J.G.5
  • 121
    • 33745220306 scopus 로고    scopus 로고
    • Plumbagin (5- Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-kappaB Activation and NF-kappaB-regulated Gene Products Through Modulation of p65 and IkappaBalpha Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents
    • Sandur SK, Ichikawa H, Sethi G, Ahn KS, Aggarwal BB (2006) Plumbagin (5- Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-kappaB Activation and NF-kappaB-regulated Gene Products Through Modulation of p65 and IkappaBalpha Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents. J Biol Chem 281: 17023-33.
    • (2006) J Biol Chem , vol.281 , pp. 17023-17033
    • Sandur, S.K.1    Ichikawa, H.2    Sethi, G.3    Ahn, K.S.4    Aggarwal, B.B.5
  • 123
    • 0344925241 scopus 로고    scopus 로고
    • The beta-catenin/ VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation
    • Zhang C, Basta T, Jensen ED, Klymkowsky MW (2003) The beta-catenin/ VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation. Development 130: 5609-24.
    • (2003) Development , vol.130 , pp. 5609-5624
    • Zhang, C.1    Basta, T.2    Jensen, E.D.3    Klymkowsky, M.W.4
  • 124
    • 0015583380 scopus 로고
    • Inhibition of protein synthesis: A mechanism of amebicide action of emetine and other structurally related compounds
    • Entner N, Grollman AP (1973) Inhibition of protein synthesis: a mechanism of amebicide action of emetine and other structurally related compounds. J Protozool 20: 160-3.
    • (1973) J Protozool , vol.20 , pp. 160-163
    • Entner, N.1    Grollman, A.P.2
  • 125
    • 4043094754 scopus 로고    scopus 로고
    • Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes
    • Sinner D, Rankin S, Lee M, Zorn AM (2004) Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. Development 131: 3069-3080.
    • (2004) Development , vol.131 , pp. 3069-3080
    • Sinner, D.1    Rankin, S.2    Lee, M.3    Zorn, A.M.4
  • 126
    • 28444446266 scopus 로고    scopus 로고
    • SOX7 and SOX18 are essential for cardiogenesis in Xenopus
    • Zhang C, Basta T, Klymkowsky MW (2005) SOX7 and SOX18 are essential for cardiogenesis in Xenopus. Dev Dyn 234: 878-891.
    • (2005) Dev Dyn , vol.234 , pp. 878-891
    • Zhang, C.1    Basta, T.2    Klymkowsky, M.W.3
  • 127
    • 12944324694 scopus 로고    scopus 로고
    • SOX7 is an immediate-early target of VegT and regulates Nodal expression in Xenopus
    • Zhang C, Basta T, Fawcett SR, Klymkowsky MW (2005) SOX7 is an immediate-early target of VegT and regulates Nodal expression in Xenopus. Dev Biol 278: 526-41.
    • (2005) Dev Biol , vol.278 , pp. 526-541
    • Zhang, C.1    Basta, T.2    Fawcett, S.R.3    Klymkowsky, M.W.4
  • 128
    • 0030219950 scopus 로고    scopus 로고
    • Negative regulation of dorsal patterning in early embryos by overexpression of XrelA, a Xenopus homologue of NF-kappa B
    • Kao KR, Lockwood A (1996) Negative regulation of dorsal patterning in early embryos by overexpression of XrelA, a Xenopus homologue of NF-kappa B. Mech Dev 58: 129-39.
    • (1996) Mech Dev , vol.58 , pp. 129-139
    • Kao, K.R.1    Lockwood, A.2
  • 129
    • 0032577486 scopus 로고    scopus 로고
    • Overexpression of a novel Xenopus rel mRNA gene induces tumors in early embryos
    • Yang S, Lockwood A, Hollett P, Ford R, Kao K (1998) Overexpression of a novel Xenopus rel mRNA gene induces tumors in early embryos. J Biol Chem 273: 13746-52.
    • (1998) J Biol Chem , vol.273 , pp. 13746-13752
    • Yang, S.1    Lockwood, A.2    Hollett, P.3    Ford, R.4    Kao, K.5
  • 130
    • 0032032469 scopus 로고    scopus 로고
    • Sulfasalazine: A potent and specific inhibitor of nuclear factor kappa B
    • Wahl C, Liptay S, Adler G, Schmid RM (1998) Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J Clin Invest 101: 1163-74.
    • (1998) J Clin Invest , vol.101 , pp. 1163-1174
    • Wahl, C.1    Liptay, S.2    Adler, G.3    Schmid, R.M.4
  • 131
    • 0342646956 scopus 로고    scopus 로고
    • Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha
    • Syrovets T, Buchele B, Gedig E, Slupsky JR, Simmet T (2000) Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha. Mol Pharmacol 58: 71-81.
    • (2000) Mol Pharmacol , vol.58 , pp. 71-81
    • Syrovets, T.1    Buchele, B.2    Gedig, E.3    Slupsky, J.R.4    Simmet, T.5
  • 132
    • 0032989028 scopus 로고    scopus 로고
    • Acetyl-11-keto-beta-boswellic acid induces apoptosis in HL-60 and CCRF-CEM cells and inhibits topoisomerase I
    • Hoernlein RF, Orlikowsky T, Zehrer C, Niethammer D, Sailer ER, et al. (1999) Acetyl-11-keto-beta-boswellic acid induces apoptosis in HL-60 and CCRF-CEM cells and inhibits topoisomerase I. J Pharmacol Exp Ther 288: 613-9.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 613-619
    • Hoernlein, R.F.1    Orlikowsky, T.2    Zehrer, C.3    Niethammer, D.4    Sailer, E.R.5
  • 133
    • 0029035973 scopus 로고
    • Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid
    • Safayhi H, Sailer ER, Ammon HP (1995) Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid. Mol Pharmacol 47: 1212-6.
    • (1995) Mol Pharmacol , vol.47 , pp. 1212-1216
    • Safayhi, H.1    Sailer, E.R.2    Ammon, H.P.3
  • 134
    • 0002159657 scopus 로고    scopus 로고
    • Whole-mount visualization of endogenous and exogenous proteins in Xenopus and other organisms
    • J. Ritcher, ed. New York: Oxford University Press. p
    • Carl T, Klymkowsky MW (1999) Whole-mount visualization of endogenous and exogenous proteins in Xenopus and other organisms. in A comparative methods approach to the study of oocytes and embryos. J. Ritcher, ed. New York: Oxford University Press. p. 291-315.
    • (1999) A comparative methods approach to the study of oocytes and embryos , pp. 291-315
    • Carl, T.1    Klymkowsky, M.W.2
  • 135
    • 0032212681 scopus 로고    scopus 로고
    • Programmed cell death during Xenopus development: A spatio-temporal analysis
    • Hensey C, Gautier J (1998) Programmed cell death during Xenopus development: a spatio-temporal analysis. Dev Biol 203: 36-48.
    • (1998) Dev Biol , vol.203 , pp. 36-48
    • Hensey, C.1    Gautier, J.2
  • 136
    • 4644370139 scopus 로고    scopus 로고
    • Early neural cell death: Dying to become neurons
    • Yeo W, Gautier J (2004) Early neural cell death: dying to become neurons. Dev Biol 274: 233-44.
    • (2004) Dev Biol , vol.274 , pp. 233-244
    • Yeo, W.1    Gautier, J.2
  • 137
    • 0024579759 scopus 로고
    • A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus
    • Dent JA, Polson AG, Klymkowsky MW (1989) A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus. Development 105: 61-74.
    • (1989) Development , vol.105 , pp. 61-74
    • Dent, J.A.1    Polson, A.G.2    Klymkowsky, M.W.3
  • 138
    • 0034010531 scopus 로고    scopus 로고
    • Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm
    • Kishi M, Mizuseki K, Sasai N, Yamazaki H, Shiota K, et al. (2000) Requirement of Sox2-mediated signaling for differentiation of early Xenopus neuroectoderm. Development 127: 791-800.
    • (2000) Development , vol.127 , pp. 791-800
    • Kishi, M.1    Mizuseki, K.2    Sasai, N.3    Yamazaki, H.4    Shiota, K.5
  • 139
    • 0030707867 scopus 로고    scopus 로고
    • Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis
    • Penzel R, Oschwald R, Chen Y, Tacke L, Grunz H (1997) Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis. Int J Dev Biol 41: 667-77.
    • (1997) Int J Dev Biol , vol.41 , pp. 667-677
    • Penzel, R.1    Oschwald, R.2    Chen, Y.3    Tacke, L.4    Grunz, H.5
  • 140
    • 0004498233 scopus 로고
    • Epidermal keratin gene expressed in embryos of Xenopus laevis
    • Jonas E, Sargent TD, Dawid IB (1985) Epidermal keratin gene expressed in embryos of Xenopus laevis. Proc Natl Acad Sci U S A 82(16): 5413-7.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , Issue.16 , pp. 5413-5417
    • Jonas, E.1    Sargent, T.D.2    Dawid, I.B.3
  • 141
    • 0025942785 scopus 로고
    • Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
    • Smith JC, Price BM, Green JB, Weigel D, Herrmann BG (1991) Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67: 79-87.
    • (1991) Cell , vol.67 , pp. 79-87
    • Smith, J.C.1    Price, B.M.2    Green, J.B.3    Weigel, D.4    Herrmann, B.G.5
  • 142
    • 0032771697 scopus 로고    scopus 로고
    • Differential expression of VegT and Antipodean protein isoforms in Xenopus
    • Stennard F, Zorn AM, Ryan K, Garrett N, Gurdon JB (1999) Differential expression of VegT and Antipodean protein isoforms in Xenopus. Mech Dev 86: 87-98.
    • (1999) Mech Dev , vol.86 , pp. 87-98
    • Stennard, F.1    Zorn, A.M.2    Ryan, K.3    Garrett, N.4    Gurdon, J.B.5
  • 143
    • 0036803297 scopus 로고    scopus 로고
    • The nodal target gene Xmenf is a component of an FGF-independent pathway of ventral mesoderm induction in Xenopus
    • Kumano G, Smith WC (2002) The nodal target gene Xmenf is a component of an FGF-independent pathway of ventral mesoderm induction in Xenopus. Mech Dev 118: 45-56.
    • (2002) Mech Dev , vol.118 , pp. 45-56
    • Kumano, G.1    Smith, W.C.2


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