Bcl-2 activates the transcription factor NFκB through the degradation of the cytoplasmic inhibitor IκBα

Journal of Biological Chemistry

Volumn 273, Issue 37, 1998, Pages 23946-23951

  De Moissac, Danielle ^a   Mustapha, Shareef ^a   Greenberg, Arnold H ^b   Kirshenbaum, Lorrie A ^a,c,d  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c HEART AND STROKE FOUNDATION OF CANADA   (Canada)

^d ST BONIFACE GENERAL HOSPITAL RESEARCH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; CYTOPLASM PROTEIN; ENZYME INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; LACTACYSTIN; PROTEASOME; PROTEIN BCL 2; SYNAPTOTAGMIN; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA BINDING; EMBRYO; HEART MUSCLE CELL; HEART VENTRICLE WALL; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; TRANSCRIPTION REGULATION;

ACETYLCYSTEINE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL LINE; CELLS, CULTURED; CYCLOHEXIMIDE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DNA; DNA-BINDING PROTEINS; HEART VENTRICLES; HUMANS; I-KAPPA B PROTEINS; MULTIENZYME COMPLEXES; MYOCARDIUM; NF-KAPPA B; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032508486     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.37.23946     Document Type: Article

References (47)

1. Sen, R., and Baltimore, D. (1986) Cell 46, 705-716
2. Lenardo, M. J., and Baltimore, D. (1989) Cell 58, 227-229
3. Grilli, M., Chiu, J. J., and Lenardo, M. J. (1993) Int. Rev. Cytol. 143, 1-62
4. Riviere, Y., Blank, V., Kourilsky, P., and Israel, A. (1991) Nature 350, 625-626
5. Baeuerle, P. A., and Baltimore, D. (1989) Genes Dev. 3, 1689-1698
6. Nolan, G. P., Ghosh, S., Liou, H. C., Tempst, P., and Baltimore, D. (1991) Cell 64, 961-969
7. Blank, V., Kourilsky, P., and Israel, A. (1992) Trends Biochem. Sci. 17, 135-140
8. Hansen, S. K., Nerlov, C., Zabel, U., Verde, P., Johnsen, M., Baeuerle, P. A., and Blasi, F. (1992) EMBO J. 11, 205-213
9. Urban, M. B., and Baeuerle, P. A. (1991) New Biol. 3, 279-288
10. Ghosh, S., Gifford, A. M., Riviere, L. R., Tempst, P., Nolan, G. P., and Baltimore, D. (1990) Cell 62, 1019-1029
11. Beg, A. A., Finco, T. S., Nantermet, P. V., and Baldwin, A. S., Jr. (1993) Mol. Cell. Biol. 13, 3301-3310
12. Krasnow, S. W., Zhang, L. Q., Leung, K. Y., Osborn, L., Kunkel, S., and Nabel, G. J. (1991) Cytokine 3, 372-379
13. Baeuerle, P. A., and Baltimore, D. (1988) Science 242, 540-546
14. Williams, R. S. (1993) Am. J. Med. Sci. 306, 129-136
15. Haskill, S., Beg, A. A., Tompkins, S. M., Morris, J. S., Yurochko, A. D., Sampson Johannes, A., Mondai, K., Ralph, P., and Baldwin, A. S., Jr. (1991) Cell 65, 1281-1289
16. Beg, A. A., Ruben, S. M., Scheinman, R. I., Haskill, S., Rosen, C. A., and Baldwin, A. S., Jr. (1992) Genes Dev. 6, 1899-1913
17. Inoue, J., Kerr, L. D., Rashid, D., Davis, N., Bose, H. R., Jr., and Verma, I. M. (1992) Proc. Natl. Acad. Sci U. S. A. 89, 4333-4337
18. Brockman, J. A., Scherer, D. C., McKinsey, T. A., Hall, S. M., Qi, X., Lee, W. Y., and Ballard, D. W. (1995) Mol. Cell Biol. 15, 2809-2818
19. McKinsey, T. A., Brockman, J. A., Scherer, D. C., Al Murrani, S. W., Green, P. L., and Ballard, D. W. (1996) Mol. Cell. Biol. 16, 2083-2090
20. Grimm, S., and Baeuerle, P. A. (1993) Biochem. J. 290, 297-308
21. Brown, K., Gerstberger, S., Carlson, L., Franzoso, G., and Siebenlist, U. (1995) Science 267, 1485-1488
22. Wu, M., Lee, H., Bellas, R. E., Schauer, S. L., Arsura, M., Katz, D., FitzGerald, M. J., Rothstein, T. L., Sherr, D. H., and Sonenshein, G. E. (1996) EMBO J. 15, 4682-4690
23. Wang, C. Y., Mayo, M. W., and Baldwin, A. S., Jr. (1996) Science 274, 784-787
24. Van Antwerp, D. J., Martin, S. J., Kafri, T., Green, D. R., and Verma, I. M. (1996) Science 274, 787-789
25. Beg, A. A., and Baltimore, D. (1996) Science 274, 782-784
26. Bellas, R. E., FitzGerald, M. J., Fausto, N., and Sonenshein, G. E. (1997) Am. J. Pathol. 151, 891-896
27. Tanaka, M., Ito, H., Adachi, S., Akimoto, H., Nishikawa, T., Kasajima, T., Marumo, F., and Hiroe, M. (1994) Circ. Res. 75, 426-433
28. Isner, J. M., Kearney, M., Bortman, S., and Passeri, J. (1995) Circulation 91, 2703-2711
29. Kirshenbaum, L. A., and de Moissac, D. (1997) Circulation 96, 1580-1585
30. Agah, R., Kirshenbaum, L. A., Abdellatif, M., Truong, L. D., Chakraborty, S., Michael, L. H., and Schneider, M. D, (1997) J. Clin. Invest. 100, 2722-2728
31. Shibasaki, F., Kondo, E., Akagi, T., and McKeon, F. (1997) Nature 386, 728-731
32. Ivanov, V. N., Deng, G., Podack, E. R., and Malek, T. R. (1995) Int. Immunol. 7, 1709-1720
33. Kirshenbaum, L. A., and Schneider, M. D. (1995) J. Biol. Chem. 270, 7791-7794
34. Kirshenbaum, L. A., MacLellan, W. R., Mazur, W., French, B. A., and Schneider, M. D. (1993) J. Clin. Invest. 92, 381-387
35. Wahl, C., Liptay, S., Adler, G., and Schmid, R. M. (1998) J. Clin. Invest. 101, 1163-1174
36. Yin, X. M., Oltval, Z. N., and Korsmeyer, S. J. (1994) Nature 369, 321-323
37. Subramanian, T., Tarodi, B., and Chinnadurai, G. (1995) Cell Growth Differ. 6, 131-137
38. Ballard, D. W., Lynn, S. P., Gardner, J. F., and Voss, E. W., Jr. (1984) J. Biol. Chem. 259, 3492-3498
39. Kirshenbaum, L. A., Abdellatif, M., Chakraborty, S., and Schneider, M. D. (1996) Dev. Biol. 179, 402-411
40. White, E., Sabbatini, P., Debbas, M., Wold, W. S., Kusher, D. I., and Gooding, L. R. (1992) Mol. Cell. Biol. 12, 2570-2580
41. Lin, K.-I, Lee, S.-H., Narayanan, R., Baraban, J. M., and Hardwick, J. M. (1995) J. Cell Biol. 131, 1149-1161
42. Linette, G. P., Li, Y., Roth, K., and Korsmeyer, S. J. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 9545-9552
43. Wang, H. G., Rapp, U. R., and Reed, J. C. (1996) Cell 87, 629-638
44. Wang, H. G., Takayama, S., Rapp, U. R., and Reed, J. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 7063-7068
45. Oltvai, Z. N., Milliman, C. L., and Korsmeyer, S. J. (1993) Cell 74, 609-619
46. Takayama, S., Sato, T., Krajewski, S., Kochel, K., Irie, S., Millan, J. A., and Reed, J. C. (1995) Cell 80, 279-284
47. Woronicz, J. D., Gao, X., Cao, Z., Rothe, M., and Goeddel, D. V. (1997) Science 278, 866-869