Triterpenoid saponins, new metalloprotease snake venom inhibitors isolated from Pentaclethra macroloba

Toxicon

Volumn 50, Issue 2, 2007, Pages 283-291

  da Silva, Jocivânia O ^a   Fernandes, Renata S ^a   Ticli, Fábio K ^a   Oliveira, Clayton Z ^a   Mazzi, Maurício V ^a   Franco, João J ^a   Giuliatti, Silvana ^a   Pereira, Paulo S ^b   Soares, Andreimar M ^a   Sampaio, Suely V ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF RIBEIRÃO PRETO   (Brazil)

Author keywords

Antihemorrhagic and antiproteolytic activity; Antivenom Brazilian plants; Pentaclethra macroloba; Proteases; Triterpenoid saponins

Indexed keywords

FIBRINOGEN; MACROLOBIN A; MACROLOBIN B; METALLOPROTEASE CLASS P I; METALLOPROTEASE CLASS P III; METALLOPROTEINASE INHIBITOR; SAPONIN; SNAKE VENOM; THROMBIN; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENVENOMATION; ENZYME INHIBITION; FIBRINOGENOLYSIS; MOUSE; NONHUMAN; PENTACLETHRA MACROLOBA; PRIORITY JOURNAL; PROTEINASE INHIBITION; SNAKE; SNAKEBITE;

ANIMALS; BACCHARIS; BLOOD COAGULATION; CARBOHYDRATE SEQUENCE; CIRCULAR DICHROISM; CROTALID VENOMS; FIBRIN; FIBRINOGEN; HEMORRHAGE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A; PLANT EXTRACTS; PLANTS; SAPONINS; SERINE PROTEINASE INHIBITORS; SNAKE VENOMS; SPECTROPHOTOMETRY, ULTRAVIOLET; TRITERPENES;

BOTHROPS; BOTHROPS JARARACUSSU; BOTHROPS NEUWIEDI; PENTACLETHRA MACROLOBA;

EID: 34447332266     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2007.03.024     Document Type: Article

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