Antihemorrhagic, antinucleolytic and other antiophidian properties of the aqueous extract from Pentaclethra macroloba

Journal of Ethnopharmacology

Volumn 100, Issue 1-2, 2005, Pages 145-152

  Da Silva, Jocivânia O ^a   Coppede, Juliana S ^b   Fernandes, Vanessa C ^b   Sant'Ana, Carolina D ^a   Ticli, Fábio K ^a   Mazzi, Maurício V ^a   Giglio, José R ^a   Pereira, Paulo S ^b   Soares, Andreimar M ^a   Sampaio, Suely V ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF RIBEIRÃO PRETO   (Brazil)

Author keywords

Antihemorrhagic; Antilethal; Antimyotoxic; Antinucleolytic activity; Antiophidian Brazilian plants; Bothrops; Pentaclethra macroloba; Snake venoms

Indexed keywords

BATROXOBIN; COAGULATING AGENT; METALLOPROTEINASE; PENTACLETHRA MACROLOBA EXTRACT; PHOSPHOLIPASE; PHOSPHOLIPASE A2; PLANT EXTRACT; PROTEIN; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; ASSAY; BLEEDING; BOTHROPS JARARACUSSU; CONTROLLED STUDY; DEATH; DRUG ACTIVITY; DRUG MECHANISM; EDEMA; ELECTROPHORESIS; ENZYME INHIBITION; FIBRINOGENOLYSIS; IN VIVO STUDY; LETHALITY; MALE; MEDICINAL PLANT; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PENTACLETHRA MACROLOBA; PROTEIN DEGRADATION; PURIFICATION; SNAKE; TOXICITY;

ANIMALS; ANTIVENINS; BOTHROPS; CROTALID VENOMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FABACEAE; HEMORRHAGE; MALE; MICE; PLANT BARK; PLANT EXTRACTS; VIPER VENOMS;

BOTHROPS; BOTHROPS ATROX; BOTHROPS JARARACUSSU; PENTACLETHRA MACROLOBA; SERPENTES;

EID: 22744457809     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2005.01.063     Document Type: Article

References (38)

1. L. de Almeida, A.C. Cintra, E.L. Veronese, A. Nomizo, J.J. Franco, E.C. Arantes, J.R. Giglio, and S.V. Sampaio Anticrotalic and antitumoral activities of gel filtration fractions of aqueous extract from Tabernaemontana catharinensis (Apocynaceae) Comparative Biochemistry and Physiology 137C 2004 19 27
2. 2 in Bothrops snake venoms: effect of chemical modifications on the enzymatic and pharmacological properties of bothropstoxin from Bothrops jararacussu Biochimie 82 2000 755 763
3. M.M. Azevedo-Marques, S.E. Hering, and P. Cupo Evidence that Crotalus durissus terrificus (South American rattlesnake) envenomation in humans causes myolysis rather than hemolysis Toxicon 25 1987 1163 1168
4. M.F.C. Batina, A.C.O. Cintra, E.L.G. Veroese, M.A.S. Lavrador, J.R. Giglio, P.S. Pereira, D.A. Dias, S.C. França, and S.V. Sampaio Inhibition of the lethal and myotoxic activities of Crotalus durissus terrificus venom by Tabernaemontana catharinensis: identification of one of the active components Planta Medica 66 2000 424 428
5. R. Biondo, A.M. Pereira, S. Marcussi, P.S. Pereira, S.C. França, and A.M. Soares Inhibition of enzymatic and pharmacological activities of some snake venoms and toxins by Mandevilla velutina (Apocynaceae) aqueous extract Biochimie 85 2003 1017 1025
6. R. Biondo, A.M. Soares, B.W. Bertoni, S.C. França, and A.M. Pereira Direct organogenesis of Mandevilla illustris (Vell) Woodson and effects of its aqueous extract on the enzymatic and toxic activities of Crotalus durissus terrificus snake venom Plant Cell Report 22 2004 549 552
7. 2 Comparative Biochemistry and Physiology 127 2000 21 31
8. M.H. Borges, A.M. Soares, V.M. Rodrigues, F. Oliveira, A.M. Franshechi, A. Rucavado, J.R. Giglio, and M.I. Homsi-Brandeburgo Neutralization of proteases from Bothrops snake venoms by the aqueous extract from Casearia sylvestris (Flacourtiaceae) Toxicon 39 2001 1863 1869
9. Esmeraldino, L.E., Souza, A.M., Sampaio, S.V., 2005. Evaluation of the effect of aqueous extract extract of Croton urucurana Baillon (Euphorbiaceae) on the hemorrhagic activity induced by the venom of B. jararaca using new techniques to quantify hemorrhagic activity in rat skin. Phytomedicine, in press.
10. N. Fatima, L.A. Tapondjou, D. Lontsi, B.L. Sondengam, Atta-Ur-Rahman, and M.I. Choudhary Quinovic acid glycosides from Mitragyna stipulosa - first examples of natural inhibitors of snake venom phosphodiesterase I Natural Product Letters 16 2002 389 393
11. L.A.F. Ferreira, O.B. Henriques, A.A.S. Andreoni, G.R.F. Vital, M.M.C. Campos, G.G. Habermehl, and V.L.G. Moraes Antivenom and biological effects of ar-tumerone isolated from Curcuma longa (Zingiberiaceae) Toxicon 30 1992 1211 1218
12. J.A. Gené, A. Roy, G. Rojas, J.M. Gutiérrez, and L. Cerdas Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rica crotaline snake venoms and their neutralization by a polyvalent antivenom Toxicon 27 1989 841 848
13. 2 Enzymes: Structure, Function and Mechanism 1997 John Wiley & Sons New York 205 222
14. J.M. Gutiérrez, C. Avila, E. Rojas, and L. Cerdas An alternative in vitro method for testing the potency of the polyvalent antivenom produced in Costa Rica Toxicon 26 1988 411 413
15. 2 Enzymes: Structure, Function and Mechanism 1997 Wiley & Sons UK 321 352
16. J.M. Gutiérrez Comprendiendo los venenos de serpientes: 50 años de investigaciones en América Latina Revista de Biologia Tropical 50 2002 377 394
17. L.F. Izidoro, V.M. Rodrigues, R.S. Rodrigues, E.V. Ferro, A. Hamaguchi, J.R. Giglio, and M.I. Homsi-Brandeburgo Neutralization of some hematological and hemostatic alterations induced by neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi pauloensis snake venom, by the aqueous extract from Casearia mariquitensis (Flacourtiaceae) Biochimie 85 2003 669 675
18. A.H. Januário, S.L. Santos, S. Marcussi, M.V. Mazzi, R.C.L.R. Pietro, D.N. Sato, J. Ellena, S.V. Sampaio, S.C. França, and A.M. Soares Neo-clerodane diterpenoid, a new metalloprotease snake venom inhibitor from Baccharis trimera (Asteraceae): anti-proteolytic and anti-hemorrhagic properties Chemico-Biological Interactions 150 2004 243 251
19. 2 myotoxin inhibitor proteins from snakes, mammals and plants Toxicon 42 2003 963 977
20. F.S. Markland Snake venoms and the hemostatic system Toxicon 36 1998 1749 1800
21. W. Martz Plant with a reputation against snakebite Toxicon 30 1992 1131 1142
22. M.V. Mazzi, S. Marcussi, G.B. Carlos, R.G. Stábeli, J.J. Franco, F.K. Ticli, A.O. Cintra, S.C. França, A.M. Soares, and S.V. Sampaio A new hemorrhagic metalloprotease from Bothrops jararacussu snake venom: isolation and biochemical characterization Toxicon 44 2004 215 223
23. W.B. Mors, M.C. Nascimento, B.M. Pereira, and N.A. Pereira Plant natural products active against snake-bite the molecular approach Phytochemistry 55 2000 627 642
24. A.L. Noe, C. Maillard, N. Rocks, M. Jost, V. Chabottaux, N.E. Sounni, E. Maquoi, D. Cataldo, and J.M. Foidart Membrane associated proteases and their inhibitors in tumor angiogenisis Journal of Clinical Pathology 57 2004 577 584
25. C. Ntayi, W. Hornebeck, and P. Bernar Involvement of matrix metalloproteinases (MMPs) in cutaneousmelanoma progression Pathologie Biologie 52 2004 154 159
26. C.L. Ownby Structure, function and biophysical aspects of the myotoxins from snake venoms Journal of Toxicology-Toxin Reviews 17 1998 213 238
27. J.T. Peterson Matrix metalloproteinase inhibitor development and remodeling of drug discovery Heart Failure Reviews 9 2004 63 79
28. V.M. Rodrigues, A.M. Soares, R. Guerra-Sá, V. Rodrigues, M.R. Fontes, and J.R. Giglio Structural and functional characterization of neuwiedase, a non-hemorrhagic fibrin(ogen)olytic metalloprotease from Bothrops neuwiedi snake venom Archives of Biochemistry and Biophysics 381 2000 213 224
29. A.R. de Roodt, S. Litwin, and S.O. Angel Hydrolysis of DNA by 17 snake venoms Comparative Biochemistry and Physiology C: Toxicology and Pharmacology 135 2003 469 479
30. P. Rosenberg Phospholipases Handbook of Toxinology 1990 Marcel Dekker New York pp. 67-277
31. 2 from Bothrops venoms by the heteromeric protein complex of Didelphis albiventris opossum serum Biochemistry and Molecular Biology International 43 1997 1091 1099
32. 2 from snake venoms: effects on catalytic and pharmacological properties Review Toxicon 42 2003 855 868
33. 2 myotoxins from Bothrops snake venoms: structure-function relationship Current Organic Chemistry 8 2004 1677 1690
34. A.M. Soares, A.H. Januário, M.V. Lourenço, A.M.S. Pereira, and P.S. Pereira Neutralizing effects of snake venoms exhibited by Brazilian plants Drugs Future 29 2004 1105 1117
35. W. Stöcker, F. Grams, U. Baumann, P. Reinemer, F.X. Gomis-Rüth, D.B. Mckay, and W. Bode The metzincins - topological and sequential relation between theastacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases Protein Science 4 1995 823 840
36. Ticli, F.K., Cambraia, R.S., Hage, L.I., Pereira, P.S., Magro, A., Fontes, M.R., França, S.C., Giglio, J.R., Soares, A.M., Sampaio, S.V., 2005. Rosmarinic acid, a new phospholipase A2 snake venom inhibitor from Cordia verbenacea (Boraginaceae): anti-inflammatory and anti-myotoxic properties. Toxicon, in press.
37. E.P. Trento, O. Garcia, C. Batalini, A. Rucavado, S.C. França, J.R. Giglio, and A.M. Soares Inhibitory properties of the anti-bothropic complex from Didelphis albiventris serum on toxic and pharmacological actions of metalloproteases and myotoxins from Bothrops asper venom Biochemistry and Pharmacology 62 2001 1521 1529
38. Veronese, E.L.G., Esmeraldino, L.E., Trombone, A.P.F., Santana, A.E., Bechara, G.H., Ketelhut, I., Cintra, A.C.O., Giglio, J.R., Sampaio, S.V., 2005. Inhibition of the myotoxic activity of Bothrops jararacussu venom and its two major myotoxins BthTX-I and BthTX-II, by the aqueous extract from Tabernaemontana catharinensis A.DC. (Apocynaceae). Phytomedicine 11, in press.