Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance

Brain Research

Volumn 1159, Issue 1, 2007, Pages 86-93

  Gabra, Bichoy H ^a   Bailey, Chris P ^b   Kelly, Eamonn ^b   Sanders, Amanda V ^a   Henderson, Graeme ^b   Smith, Forrest L ^c   Dewey, William L ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c HARDING UNIVERSITY   (United States)

Author keywords

Antinociception; Morphine; Okadaic acid; Protein kinase A; Protein kinase C; Protein phosphatase; Tolerance

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; BISINDOLYLMALEIMIDE; MORPHINE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG INHIBITION; DRUG POTENTIATION; ENZYME ACTIVITY; MALE; MORPHINE TOLERANCE; MOUSE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; DRUG INTERACTIONS; DRUG TOLERANCE; ENZYME INHIBITORS; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MORPHINE; NARCOTICS; PAIN MEASUREMENT; PERIAQUEDUCTAL GRAY; PHOSPHOPROTEIN PHOSPHATASE; REACTION TIME;

ANIMALIA; MUS;

EID: 34447326444     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.05.017     Document Type: Article

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