Effects of spinal versus supraspinal administration of cyclic nucleotide-dependent protein kinase inhibitors on morphine tolerance in mice

Drug and Alcohol Dependence

Volumn 44, Issue 1, 1997, Pages 41-46

  Bernstein, M A ^a   Welch, S P ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Antinociception; Hyperalgesia; Morphine tolerance; Protein kinase

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; KT 5720; KT 5823; MORPHINE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

ANALGESIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; HYPERALGESIA; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; MALE; MORPHINE TOLERANCE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RESPIRATION DEPRESSION; SPINAL CORD; SUBCUTANEOUS DRUG ADMINISTRATION; TAIL FLICK TEST;

ALKALOIDS; ANIMALS; BRAIN; CARBAZOLES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; ENZYME INHIBITORS; INDOLES; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SUBCUTANEOUS; MICE; MICE, INBRED ICR; MORPHINE DEPENDENCE; PAIN THRESHOLD; PYRROLES; SPINAL CORD; UP-REGULATION;

EID: 0031561764     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-8716(96)01320-8     Document Type: Article

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