메뉴 건너뛰기




Volumn 25, Issue 5, 2007, Pages 483-514

Micropumps, microvalves, and micromixers within PCR microfluidic chips: Advances and trends

Author keywords

Microfluidic chip; Micromixers; Micropumps; Microvalves; Polymerase chain reaction (PCR)

Indexed keywords

MICROFLUIDIC CHIPS; MICROMIXERS; MICROPUMPS; MICROVALVES; POLYMERASE CHAIN REACTIONS (PCR);

EID: 34447299421     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2007.05.003     Document Type: Review
Times cited : (353)

References (97)
  • 1
    • 0034658921 scopus 로고    scopus 로고
    • A miniature integrated device for automated multistep genetic assays
    • Anderson R.C., Su X., Bogdan G.J., and Fenton J. A miniature integrated device for automated multistep genetic assays. Nucleic Acids Res 28 (2000) e60
    • (2000) Nucleic Acids Res , vol.28
    • Anderson, R.C.1    Su, X.2    Bogdan, G.J.3    Fenton, J.4
  • 2
    • 0037096670 scopus 로고    scopus 로고
    • Micro total analysis systems: 2. Analytical standard operations and applications
    • Auroux P.-A., Iossifidis D., Reyes D.R., and Manz A. Micro total analysis systems: 2. Analytical standard operations and applications. Anal Chem 74 (2002) 2637-2652
    • (2002) Anal Chem , vol.74 , pp. 2637-2652
    • Auroux, P.-A.1    Iossifidis, D.2    Reyes, D.R.3    Manz, A.4
  • 3
    • 0034812658 scopus 로고    scopus 로고
    • High-density microvalve arrays for sample processing in PCR chips
    • Baechi D., Buser R., and Dual J. High-density microvalve arrays for sample processing in PCR chips. Biomed Microdevices 3 3 (2001) 183-190
    • (2001) Biomed Microdevices , vol.3 , Issue.3 , pp. 183-190
    • Baechi, D.1    Buser, R.2    Dual, J.3
  • 4
    • 0035888342 scopus 로고    scopus 로고
    • A minute magneto hydro dynamic (MHD) mixer
    • Bau H.H., Zhong J., and Yi M. A minute magneto hydro dynamic (MHD) mixer. Sens Actuators B Chem 79 (2001) 207-215
    • (2001) Sens Actuators B Chem , vol.79 , pp. 207-215
    • Bau, H.H.1    Zhong, J.2    Yi, M.3
  • 8
    • 18544374127 scopus 로고    scopus 로고
    • Real-time PCR detection of Listeria monocytogenes using an integrated microfluidics platform
    • Cady N.C., Stelick S., Kunnavakkam M.V., and Batt C.A. Real-time PCR detection of Listeria monocytogenes using an integrated microfluidics platform. Sens Actuators B Chem 107 (2005) 332-341
    • (2005) Sens Actuators B Chem , vol.107 , pp. 332-341
    • Cady, N.C.1    Stelick, S.2    Kunnavakkam, M.V.3    Batt, C.A.4
  • 9
    • 33751212797 scopus 로고    scopus 로고
    • Automated microdroplet platform for sample manipulation and polymerase chain reaction
    • Chabert M., Dorfman K.D., de Cremoux P., Roeraade J., and Viovy J.L. Automated microdroplet platform for sample manipulation and polymerase chain reaction. Anal Chem 78 22 (2006) 7722-7728
    • (2006) Anal Chem , vol.78 , Issue.22 , pp. 7722-7728
    • Chabert, M.1    Dorfman, K.D.2    de Cremoux, P.3    Roeraade, J.4    Viovy, J.L.5
  • 10
    • 33747062694 scopus 로고    scopus 로고
    • Integrated polymerase chain reaction chips utilizing digital microfluidics
    • Chang Y.H., Lee G.B., Huang F.C., Chen Y.Y., and Lin J.L. Integrated polymerase chain reaction chips utilizing digital microfluidics. Biomed Microdevices 8 3 (2006) 215-225
    • (2006) Biomed Microdevices , vol.8 , Issue.3 , pp. 215-225
    • Chang, Y.H.1    Lee, G.B.2    Huang, F.C.3    Chen, Y.Y.4    Lin, J.L.5
  • 11
    • 12244290582 scopus 로고    scopus 로고
    • Electrokinetically synchronized polymerase chain reaction microchip fabricated in polycarbonate
    • Chen J.F., Wabuyele M., Chen H.W., Patterson D., Hupert M., Shadpour H., et al. Electrokinetically synchronized polymerase chain reaction microchip fabricated in polycarbonate. Anal Chem 77 2 (2005) 658-666
    • (2005) Anal Chem , vol.77 , Issue.2 , pp. 658-666
    • Chen, J.F.1    Wabuyele, M.2    Chen, H.W.3    Patterson, D.4    Hupert, M.5    Shadpour, H.6
  • 12
    • 27744534115 scopus 로고    scopus 로고
    • Thermal-actuated, phase change flow control for microfluidic systems
    • Chen Z.Y., Wang J., Qian S.Z., and Bau H.H. Thermal-actuated, phase change flow control for microfluidic systems. Lab Chip 5 (2005) 1277-1285
    • (2005) Lab Chip , vol.5 , pp. 1277-1285
    • Chen, Z.Y.1    Wang, J.2    Qian, S.Z.3    Bau, H.H.4
  • 14
    • 0037233259 scopus 로고    scopus 로고
    • Continuous segmented-flow polymerase chain reaction for high-throughput miniaturized DNA amplification
    • Curcio M., and Roeraade J. Continuous segmented-flow polymerase chain reaction for high-throughput miniaturized DNA amplification. Anal Chem 75 1 (2003) 1-7
    • (2003) Anal Chem , vol.75 , Issue.1 , pp. 1-7
    • Curcio, M.1    Roeraade, J.2
  • 15
    • 34447313613 scopus 로고    scopus 로고
    • Demer F.M., Ink jet printer. US Patent 3 787 884 (1974).
  • 16
    • 33745254515 scopus 로고    scopus 로고
    • Micro total analysis systems. Latest advancements and trends
    • Dittrich P.S., Tachikawa K., and Manz A. Micro total analysis systems. Latest advancements and trends. Anal Chem 78 (2006) 3887-3908
    • (2006) Anal Chem , vol.78 , pp. 3887-3908
    • Dittrich, P.S.1    Tachikawa, K.2    Manz, A.3
  • 17
    • 20444390163 scopus 로고    scopus 로고
    • Contamination-free continuous flow microfluidic polymerase chain reaction for quantitative and clinical applications
    • Dorfman K.D., Chabert M., Codarbox J.H., Rousseau G., de Cremoux P., and Viovy J.L. Contamination-free continuous flow microfluidic polymerase chain reaction for quantitative and clinical applications. Anal Chem 77 11 (2005) 3700-3704
    • (2005) Anal Chem , vol.77 , Issue.11 , pp. 3700-3704
    • Dorfman, K.D.1    Chabert, M.2    Codarbox, J.H.3    Rousseau, G.4    de Cremoux, P.5    Viovy, J.L.6
  • 18
    • 33745685152 scopus 로고    scopus 로고
    • On-chip pressure injection for integration of infrared-mediated DNA amplification with electrophoretic separation
    • Easley C.J., Karlinsey J.M., and Landers J.P. On-chip pressure injection for integration of infrared-mediated DNA amplification with electrophoretic separation. Lab Chip 6 (2006) 601-610
    • (2006) Lab Chip , vol.6 , pp. 601-610
    • Easley, C.J.1    Karlinsey, J.M.2    Landers, J.P.3
  • 20
    • 0141993635 scopus 로고    scopus 로고
    • The new generation of microvalves
    • Felton M.J. The new generation of microvalves. Anal Chem 75 19 (2003) 429A-432A
    • (2003) Anal Chem , vol.75 , Issue.19
    • Felton, M.J.1
  • 22
    • 33746446015 scopus 로고    scopus 로고
    • Microfluidic handling of PCR solution and DNA amplification on a reaction chamber array biochip
    • Gong H., Ramalingam N., Chen L., Che J., Wang Q., Wang Y., et al. Microfluidic handling of PCR solution and DNA amplification on a reaction chamber array biochip. Biomed Microdevices 8 (2006) 167-176
    • (2006) Biomed Microdevices , vol.8 , pp. 167-176
    • Gong, H.1    Ramalingam, N.2    Chen, L.3    Che, J.4    Wang, Q.5    Wang, Y.6
  • 23
    • 0037378989 scopus 로고    scopus 로고
    • Monolithic membrane valves and diaphragm pumps for practical large-scale integration into glass microfluidic devices
    • Grover W.H., Skelley A.M., Liu C.N., Lagally E.T., and Mathies R.A. Monolithic membrane valves and diaphragm pumps for practical large-scale integration into glass microfluidic devices. Sens Actuators B Chem 89 (2003) 315-323
    • (2003) Sens Actuators B Chem , vol.89 , pp. 315-323
    • Grover, W.H.1    Skelley, A.M.2    Liu, C.N.3    Lagally, E.T.4    Mathies, R.A.5
  • 24
    • 1242310196 scopus 로고    scopus 로고
    • Ice valve for a mini/micro flow channel
    • Gui L., and Liu J. Ice valve for a mini/micro flow channel. J Micromechanics Microengineering 14 (2004) 242-246
    • (2004) J Micromechanics Microengineering , vol.14 , pp. 242-246
    • Gui, L.1    Liu, J.2
  • 25
    • 33748509104 scopus 로고    scopus 로고
    • Numerical simulation of heat transfer and electrokinetic flow in an electroosmosis-based continuous-flow PCR chip
    • Gui L., and Ren C.L. Numerical simulation of heat transfer and electrokinetic flow in an electroosmosis-based continuous-flow PCR chip. Anal Chem 78 17 (2006) 6215-6222
    • (2006) Anal Chem , vol.78 , Issue.17 , pp. 6215-6222
    • Gui, L.1    Ren, C.L.2
  • 27
    • 0035444118 scopus 로고    scopus 로고
    • Mathematical modeling of drop mixing in a slit-type microchannel
    • Handique K., and Burns M.A. Mathematical modeling of drop mixing in a slit-type microchannel. J Micromechanics Microengineering 11 (2001) 548-554
    • (2001) J Micromechanics Microengineering , vol.11 , pp. 548-554
    • Handique, K.1    Burns, M.A.2
  • 28
    • 33645223640 scopus 로고    scopus 로고
    • Polymerase chain reaction/ligase detection reaction/hybridization assays using flow-through microfluidic devices for the detection of low-abundant DNA point mutations
    • Hashimoto M., Barany F., and Soper S.A. Polymerase chain reaction/ligase detection reaction/hybridization assays using flow-through microfluidic devices for the detection of low-abundant DNA point mutations. Biosens Bioelectron 21 10 (2006) 1915-1923
    • (2006) Biosens Bioelectron , vol.21 , Issue.10 , pp. 1915-1923
    • Hashimoto, M.1    Barany, F.2    Soper, S.A.3
  • 29
    • 13444257560 scopus 로고    scopus 로고
    • Rapid microvolume PCR of DNA confirmed by microchip electrophoresis
    • Hataoka Y., Zhang L.H., Yukimasa T., and Baba Y. Rapid microvolume PCR of DNA confirmed by microchip electrophoresis. Anal Sci 21 (2005) 53-56
    • (2005) Anal Sci , vol.21 , pp. 53-56
    • Hataoka, Y.1    Zhang, L.H.2    Yukimasa, T.3    Baba, Y.4
  • 30
    • 0035958613 scopus 로고    scopus 로고
    • Capillary-based fully integrated and automated system for nanoliter polymerase chain reaction analysis directly from cheek cells
    • He Y., Zhang Y.H., and Yeung E.S. Capillary-based fully integrated and automated system for nanoliter polymerase chain reaction analysis directly from cheek cells. J Chromatogr A 924 (2001) 271-284
    • (2001) J Chromatogr A , vol.924 , pp. 271-284
    • He, Y.1    Zhang, Y.H.2    Yeung, E.S.3
  • 31
    • 14544286392 scopus 로고    scopus 로고
    • Micromixers - a review on passive and active mixing principles
    • Hessel V., Löwe H., and Schönfeld F. Micromixers - a review on passive and active mixing principles. Chem Eng Sci 60 (2005) 2479-2501
    • (2005) Chem Eng Sci , vol.60 , pp. 2479-2501
    • Hessel, V.1    Löwe, H.2    Schönfeld, F.3
  • 32
    • 33847348965 scopus 로고    scopus 로고
    • Integrated microelectronic device for label-free nucleic acid amplification and detection
    • Hou C.-S.J., Godin M., Payer K., Chakrabarti R., and Manalis S.R. Integrated microelectronic device for label-free nucleic acid amplification and detection. Lab Chip 7 (2007) 347-354
    • (2007) Lab Chip , vol.7 , pp. 347-354
    • Hou, C.-S.J.1    Godin, M.2    Payer, K.3    Chakrabarti, R.4    Manalis, S.R.5
  • 33
    • 30744457329 scopus 로고    scopus 로고
    • Electrokinetically controlled real-time polymerase chain reaction in microchannel using Joule heating effect
    • Hu G.Q., Xiang Q., Fu R., Xu B., Venditti R., and Li D.Q. Electrokinetically controlled real-time polymerase chain reaction in microchannel using Joule heating effect. Anal Chim Acta 557 (2006) 146-151
    • (2006) Anal Chim Acta , vol.557 , pp. 146-151
    • Hu, G.Q.1    Xiang, Q.2    Fu, R.3    Xu, B.4    Venditti, R.5    Li, D.Q.6
  • 34
    • 33748348843 scopus 로고    scopus 로고
    • An integrated microfluidic chip for DNA/RNA amplification, electrophoresis separation and on-line optical detection
    • Huang F.C., Liao C.S., and Lee G.B. An integrated microfluidic chip for DNA/RNA amplification, electrophoresis separation and on-line optical detection. Electrophoresis 27 (2006) 3297-3305
    • (2006) Electrophoresis , vol.27 , pp. 3297-3305
    • Huang, F.C.1    Liao, C.S.2    Lee, G.B.3
  • 35
    • 0032748858 scopus 로고    scopus 로고
    • Microfluidic devices for electrokinematically driven parallel and serial mixing
    • Jacobson S.C., McKnight T.E., and Ramsey J.M. Microfluidic devices for electrokinematically driven parallel and serial mixing. Anal Chem 71 (1999) 4455-4459
    • (1999) Anal Chem , vol.71 , pp. 4455-4459
    • Jacobson, S.C.1    McKnight, T.E.2    Ramsey, J.M.3
  • 36
    • 4344632456 scopus 로고    scopus 로고
    • The science and applications of droplets in microfluidic devices
    • Jensen K., and Lee A. The science and applications of droplets in microfluidic devices. Lab Chip 4 (2004) 31N-32N
    • (2004) Lab Chip , vol.4
    • Jensen, K.1    Lee, A.2
  • 37
    • 33750224432 scopus 로고    scopus 로고
    • Automated screening using microfluidic chip-based PCR and product detection to assess risk of BK virus-associated nephropathy in renal transplant recipients
    • Kaigala G.V., Huskins R.J., Preiksaitis J., Pang X.-L., Pilarski L.M., and Backhouse C.J. Automated screening using microfluidic chip-based PCR and product detection to assess risk of BK virus-associated nephropathy in renal transplant recipients. Electrophoresis 27 (2006) 3753-3763
    • (2006) Electrophoresis , vol.27 , pp. 3753-3763
    • Kaigala, G.V.1    Huskins, R.J.2    Preiksaitis, J.3    Pang, X.-L.4    Pilarski, L.M.5    Backhouse, C.J.6
  • 38
    • 0041837248 scopus 로고    scopus 로고
    • Integrating polymerase chain reaction, valving, and electrophoresis in a plastic device for bacterial detection
    • Koh C.G., Tan W., Zhao M., Ricco A.J., and Fan Z.H. Integrating polymerase chain reaction, valving, and electrophoresis in a plastic device for bacterial detection. Anal Chem 75 17 (2003) 4591-4598
    • (2003) Anal Chem , vol.75 , Issue.17 , pp. 4591-4598
    • Koh, C.G.1    Tan, W.2    Zhao, M.3    Ricco, A.J.4    Fan, Z.H.5
  • 39
    • 0033741544 scopus 로고    scopus 로고
    • Thin film shape memory microvalves with adjustable operation temperature
    • Kohl M., Dittmann D., Quandt E., and Winzek B. Thin film shape memory microvalves with adjustable operation temperature. Sens Actuators A Phys 83 (2000) 214-219
    • (2000) Sens Actuators A Phys , vol.83 , pp. 214-219
    • Kohl, M.1    Dittmann, D.2    Quandt, E.3    Winzek, B.4
  • 40
    • 0032524099 scopus 로고    scopus 로고
    • Chemical amplification: continuous-flow PCR on a chip
    • Kopp M.U., de Mello A.J., and Manz A. Chemical amplification: continuous-flow PCR on a chip. Science 280 (1998) 1046-1048
    • (1998) Science , vol.280 , pp. 1046-1048
    • Kopp, M.U.1    de Mello, A.J.2    Manz, A.3
  • 41
    • 0033743165 scopus 로고    scopus 로고
    • Monolithic integrated microfluidic DNA amplification and capillary electrophoresis analysis system
    • Lagally E.T., Simpson P.C., and Mathies R.A. Monolithic integrated microfluidic DNA amplification and capillary electrophoresis analysis system. Sens Actuators B Chem 63 (2000) 138-146
    • (2000) Sens Actuators B Chem , vol.63 , pp. 138-146
    • Lagally, E.T.1    Simpson, P.C.2    Mathies, R.A.3
  • 42
    • 0141995822 scopus 로고    scopus 로고
    • Fully integrated PCR-capillary electrophoresis microsystem for DNA analysis
    • Lagally E.T., Emrich C.A., and Mathies R.A. Fully integrated PCR-capillary electrophoresis microsystem for DNA analysis. Lab Chip 1 (2001) 102-107
    • (2001) Lab Chip , vol.1 , pp. 102-107
    • Lagally, E.T.1    Emrich, C.A.2    Mathies, R.A.3
  • 43
    • 0035253329 scopus 로고    scopus 로고
    • Single-molecule DNA amplification and analysis in an integrated microfluidic device
    • Lagally E.T., Medintz I., and Mathies R.A. Single-molecule DNA amplification and analysis in an integrated microfluidic device. Anal Chem 73 3 (2001) 565-570
    • (2001) Anal Chem , vol.73 , Issue.3 , pp. 565-570
    • Lagally, E.T.1    Medintz, I.2    Mathies, R.A.3
  • 45
    • 2642554646 scopus 로고    scopus 로고
    • Integrated portable genetic analysis microsystem for pathogen/infectious disease detection
    • Lagally E.T., Scherer J.R., Blazej R.G., Toriello N.M., Diep B.A., Ramchandani M., et al. Integrated portable genetic analysis microsystem for pathogen/infectious disease detection. Anal Chem 76 11 (2004) 3162-3170
    • (2004) Anal Chem , vol.76 , Issue.11 , pp. 3162-3170
    • Lagally, E.T.1    Scherer, J.R.2    Blazej, R.G.3    Toriello, N.M.4    Diep, B.A.5    Ramchandani, M.6
  • 47
    • 18744404791 scopus 로고    scopus 로고
    • Integrated microfluidic systems for cell lysis, mixing/pumping and DNA amplification
    • Lee C.Y., Lee G.B., Lin J.L., Huang F.C., and Liao C.S. Integrated microfluidic systems for cell lysis, mixing/pumping and DNA amplification. J Micromechanics Microengineering 15 (2005) 1215-1223
    • (2005) J Micromechanics Microengineering , vol.15 , pp. 1215-1223
    • Lee, C.Y.1    Lee, G.B.2    Lin, J.L.3    Huang, F.C.4    Liao, C.S.5
  • 48
    • 33644746296 scopus 로고    scopus 로고
    • A simple, valveless microfluidic sample preparation device for extraction and amplification of DNA from nanoliter-volume samples
    • Legendre L.A., Bienvenue J.M., Roper M.G., Ferrance J.P., and Landers J.P. A simple, valveless microfluidic sample preparation device for extraction and amplification of DNA from nanoliter-volume samples. Anal Chem 78 5 (2006) 1444-1451
    • (2006) Anal Chem , vol.78 , Issue.5 , pp. 1444-1451
    • Legendre, L.A.1    Bienvenue, J.M.2    Roper, M.G.3    Ferrance, J.P.4    Landers, J.P.5
  • 49
    • 0033743245 scopus 로고    scopus 로고
    • An AC magnetohydrodynamic micropump
    • Lemoff A.V., and Lee A.P. An AC magnetohydrodynamic micropump. Sens Actuators B Chem 63 3 (2000) 138-146
    • (2000) Sens Actuators B Chem , vol.63 , Issue.3 , pp. 138-146
    • Lemoff, A.V.1    Lee, A.P.2
  • 51
    • 33846587591 scopus 로고    scopus 로고
    • Integrated reverse transcription polymerase chain reaction systems for virus detection
    • Lien K.Y., Lee W.C., Lei H.Y., and Lee G.B. Integrated reverse transcription polymerase chain reaction systems for virus detection. Biosens Bioelectron 22 (2007) 1739-1748
    • (2007) Biosens Bioelectron , vol.22 , pp. 1739-1748
    • Lien, K.Y.1    Lee, W.C.2    Lei, H.Y.3    Lee, G.B.4
  • 53
    • 0036079139 scopus 로고    scopus 로고
    • A nanoliter rotary device for polymerase chain reaction
    • Liu J., Enzelberger M., and Quake S. A nanoliter rotary device for polymerase chain reaction. Eletrophoresis 23 (2002) 1531-1536
    • (2002) Eletrophoresis , vol.23 , pp. 1531-1536
    • Liu, J.1    Enzelberger, M.2    Quake, S.3
  • 55
    • 0036645755 scopus 로고    scopus 로고
    • DNA amplification and hybridization assays in integrated plastic monolithic devices
    • Liu Y., Rauch C.B., Stevens R.L., Lenigk R., Yang J., Rhine D.B., et al. DNA amplification and hybridization assays in integrated plastic monolithic devices. Anal Chem 74 13 (2002) 3063-3070
    • (2002) Anal Chem , vol.74 , Issue.13 , pp. 3063-3070
    • Liu, Y.1    Rauch, C.B.2    Stevens, R.L.3    Lenigk, R.4    Yang, J.5    Rhine, D.B.6
  • 56
    • 0141816971 scopus 로고    scopus 로고
    • Solving the 'World-to-Chip' interface problem with a microfluidic matrix
    • Liu J., Hansen C., and Quake S.R. Solving the 'World-to-Chip' interface problem with a microfluidic matrix. Anal Chem 75 (2003) 4718-4723
    • (2003) Anal Chem , vol.75 , pp. 4718-4723
    • Liu, J.1    Hansen, C.2    Quake, S.R.3
  • 58
    • 1342285628 scopus 로고    scopus 로고
    • Single-use, thermally actuated paraffin valves for microfluidic applications
    • Liu R.H., Yang J., Lenigk R., Bonanno J., and Grodzinski P. Single-use, thermally actuated paraffin valves for microfluidic applications. Sens Actuators B Chem 98 (2004) 328-336
    • (2004) Sens Actuators B Chem , vol.98 , pp. 328-336
    • Liu, R.H.1    Yang, J.2    Lenigk, R.3    Bonanno, J.4    Grodzinski, P.5
  • 59
    • 1842477059 scopus 로고    scopus 로고
    • Self-contained, fully integrated biochip for sample preparation, polymerase chain reaction amplification, and DNA microarray detection
    • Liu R.H., Yang J., Lenigk R., Bonanno J., and Grodzinski P. Self-contained, fully integrated biochip for sample preparation, polymerase chain reaction amplification, and DNA microarray detection. Anal Chem 76 7 (2004) 1824-1831
    • (2004) Anal Chem , vol.76 , Issue.7 , pp. 1824-1831
    • Liu, R.H.1    Yang, J.2    Lenigk, R.3    Bonanno, J.4    Grodzinski, P.5
  • 60
    • 33746798062 scopus 로고    scopus 로고
    • Multichannel PCR-CE microdevice for genetic analysis
    • Liu C.N., Toriello N.M., and Mathies R.A. Multichannel PCR-CE microdevice for genetic analysis. Anal Chem 78 15 (2006) 5474-5479
    • (2006) Anal Chem , vol.78 , Issue.15 , pp. 5474-5479
    • Liu, C.N.1    Toriello, N.M.2    Mathies, R.A.3
  • 61
    • 33847676392 scopus 로고    scopus 로고
    • Integrated portable PCR-capillary electrophoresis microsystem for rapid forensic short tandem repeat typing
    • Liu P., Seo T.S., Beyor N., Shin K., Scherer J.R., and Mathies R.A. Integrated portable PCR-capillary electrophoresis microsystem for rapid forensic short tandem repeat typing. Anal Chem, 79 5 (2007) 1881-1889
    • (2007) Anal Chem , vol.79 , Issue.5 , pp. 1881-1889
    • Liu, P.1    Seo, T.S.2    Beyor, N.3    Shin, K.4    Scherer, J.R.5    Mathies, R.A.6
  • 62
    • 0025207507 scopus 로고
    • Miniaturized total analysis systems: a novel concept for chemical sensing
    • Manz A., Graber N., and Widmer H.M. Miniaturized total analysis systems: a novel concept for chemical sensing. Sens Actuators B Chem 1 1 (1990) 244-248
    • (1990) Sens Actuators B Chem , vol.1 , Issue.1 , pp. 244-248
    • Manz, A.1    Graber, N.2    Widmer, H.M.3
  • 65
    • 22044437415 scopus 로고    scopus 로고
    • Automated chip-based device for simple and fast nucleic acid amplification
    • Münchow G., Dadic D., Doffing F., Hardt S., and Drese K.S. Automated chip-based device for simple and fast nucleic acid amplification. Expert Rev Mol Diagn 5 4 (2005) 613-620
    • (2005) Expert Rev Mol Diagn , vol.5 , Issue.4 , pp. 613-620
    • Münchow, G.1    Dadic, D.2    Doffing, F.3    Hardt, S.4    Drese, K.S.5
  • 69
    • 23644432068 scopus 로고    scopus 로고
    • World-to-chip microfluidic interface with built-in valves for multichamber chip-based PCR assays
    • Oh K.W., Park C., Namkoong K., Kim J., Ock K.S., Kim S., et al. World-to-chip microfluidic interface with built-in valves for multichamber chip-based PCR assays. Lab Chip 5 (2005) 845-850
    • (2005) Lab Chip , vol.5 , pp. 845-850
    • Oh, K.W.1    Park, C.2    Namkoong, K.3    Kim, J.4    Ock, K.S.5    Kim, S.6
  • 70
    • 26844540072 scopus 로고    scopus 로고
    • A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip
    • Oh K.W., Park C., and Namkoong K. A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro PCR chip. Proc. IEEE MEMS (2005) 714-717
    • (2005) Proc. IEEE MEMS , pp. 714-717
    • Oh, K.W.1    Park, C.2    Namkoong, K.3
  • 71
    • 3042778214 scopus 로고    scopus 로고
    • Phase change microvalve for integrated devices
    • Pal R., Yang M., Johnson B.N., Burke D.T., and Burns M.A. Phase change microvalve for integrated devices. Anal Chem 76 13 (2004) 3740-3748
    • (2004) Anal Chem , vol.76 , Issue.13 , pp. 3740-3748
    • Pal, R.1    Yang, M.2    Johnson, B.N.3    Burke, D.T.4    Burns, M.A.5
  • 72
    • 26844507929 scopus 로고    scopus 로고
    • An integrated microfluidic device for influenza and other genetic analyses
    • Pal R., Yang M., Lin R., Johnson B.N., Srivastava N., Razzacki S.Z., et al. An integrated microfluidic device for influenza and other genetic analyses. Lab Chip 5 (2005) 1024-1032
    • (2005) Lab Chip , vol.5 , pp. 1024-1032
    • Pal, R.1    Yang, M.2    Lin, R.3    Johnson, B.N.4    Srivastava, N.5    Razzacki, S.Z.6
  • 73
    • 26244459115 scopus 로고    scopus 로고
    • An adaptable microvalving system for on-chip polymerase chain reactions
    • Pilarski P.M., Adamia S., and Backhouse C.J. An adaptable microvalving system for on-chip polymerase chain reactions. J Immunol Methods 305 (2005) 48-58
    • (2005) J Immunol Methods , vol.305 , pp. 48-58
    • Pilarski, P.M.1    Adamia, S.2    Backhouse, C.J.3
  • 76
    • 33847140162 scopus 로고    scopus 로고
    • An integrated genetic analysis microfluidic platform with valves and a PCR chip reusability method to avoid contamination
    • Prakash R., and Kaler K.V.I.S. An integrated genetic analysis microfluidic platform with valves and a PCR chip reusability method to avoid contamination. Microfluid Nanofluid 3 (2007) 177-187
    • (2007) Microfluid Nanofluid , vol.3 , pp. 177-187
    • Prakash, R.1    Kaler, K.V.I.S.2
  • 77
    • 0034711410 scopus 로고    scopus 로고
    • From micro to nano fabrication with soft materials
    • Quake S.R., and Scherer A. From micro to nano fabrication with soft materials. Science 290 (2000) 1536-1540
    • (2000) Science , vol.290 , pp. 1536-1540
    • Quake, S.R.1    Scherer, A.2
  • 78
    • 0037096666 scopus 로고    scopus 로고
    • Micro total analysis systems: 1. Introduction, theory, and technology
    • Reyes D.R., Iossifidis D., Auroux P.-A., and Manz A. Micro total analysis systems: 1. Introduction, theory, and technology. Anal Chem 74 (2002) 2623-2636
    • (2002) Anal Chem , vol.74 , pp. 2623-2636
    • Reyes, D.R.1    Iossifidis, D.2    Auroux, P.-A.3    Manz, A.4
  • 79
    • 0022372670 scopus 로고
    • Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia
    • Saiki R.K., Scharf F., Faloona F., Mullis K.B., Horn G.T., Erlich H.A., et al. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230 (1985) 1350-1354
    • (1985) Science , vol.230 , pp. 1350-1354
    • Saiki, R.K.1    Scharf, F.2    Faloona, F.3    Mullis, K.B.4    Horn, G.T.5    Erlich, H.A.6
  • 80
    • 0025698138 scopus 로고
    • Piezoelectric micropump with three valves working peristaltically
    • Smits J.G. Piezoelectric micropump with three valves working peristaltically. Sens Actuators A Phys 21-23 (1990) 203-206
    • (1990) Sens Actuators A Phys , vol.21-23 , pp. 203-206
    • Smits, J.G.1
  • 81
    • 0033745074 scopus 로고    scopus 로고
    • Microactuators and their technologies
    • Thielicke E., and Obermeier E. Microactuators and their technologies. Mechatronics, 10 (2000) 431-455
    • (2000) Mechatronics , vol.10 , pp. 431-455
    • Thielicke, E.1    Obermeier, E.2
  • 82
    • 0037131390 scopus 로고    scopus 로고
    • Microfluidic large-scale integration
    • Thorsen T., Maerkl S.J., and Quake S.R. Microfluidic large-scale integration. Science 298 (2002) 580-584
    • (2002) Science , vol.298 , pp. 580-584
    • Thorsen, T.1    Maerkl, S.J.2    Quake, S.R.3
  • 83
    • 33845327545 scopus 로고    scopus 로고
    • Multichannel reverse transcription-polymerase chain reaction microdevice for rapid gene expression and biomarker analysis
    • Toriello N.M., Liu C.N., and Mathies R.A. Multichannel reverse transcription-polymerase chain reaction microdevice for rapid gene expression and biomarker analysis. Anal Chem 78 23 (2006) 7997-8003
    • (2006) Anal Chem , vol.78 , Issue.23 , pp. 7997-8003
    • Toriello, N.M.1    Liu, C.N.2    Mathies, R.A.3
  • 84
    • 0034615958 scopus 로고    scopus 로고
    • Monolithic microfabricated valves and pumps by multilayer soft lithography
    • Unger M.A., Chou H.-P., Thorsen T., Scherer A., and Quake S.R. Monolithic microfabricated valves and pumps by multilayer soft lithography. Science 288 (2000) 113-116
    • (2000) Science , vol.288 , pp. 113-116
    • Unger, M.A.1    Chou, H.-P.2    Thorsen, T.3    Scherer, A.4    Quake, S.R.5
  • 86
    • 0024101674 scopus 로고
    • A piezoelectric micropump based on micromachining of silicon
    • Van Lintel H.T.G., van de Pol F.C.M., and Bouwstra S. A piezoelectric micropump based on micromachining of silicon. Sens Actuators 15 (1988) 153-167
    • (1988) Sens Actuators , vol.15 , pp. 153-167
    • Van Lintel, H.T.G.1    van de Pol, F.C.M.2    Bouwstra, S.3
  • 87
    • 2942547450 scopus 로고    scopus 로고
    • Micro total analysis systems: recent developments
    • Vilkner T., Janasek D., and Manz A. Micro total analysis systems: recent developments. Anal Chem 76 (2004) 3373-3386
    • (2004) Anal Chem , vol.76 , pp. 3373-3386
    • Vilkner, T.1    Janasek, D.2    Manz, A.3
  • 88
    • 33645231834 scopus 로고    scopus 로고
    • Segmenting fluid effect on PCR reactions in microfluidic platforms
    • Walsh E.J., King C., Grimes R., and Gonzalez A. Segmenting fluid effect on PCR reactions in microfluidic platforms. Biomed Microdevices 7 4 (2005) 269-272
    • (2005) Biomed Microdevices , vol.7 , Issue.4 , pp. 269-272
    • Walsh, E.J.1    King, C.2    Grimes, R.3    Gonzalez, A.4
  • 89
    • 33645222934 scopus 로고    scopus 로고
    • Self-actuated, thermo-responsive hydrogel valves for lab on a chip
    • Wang J., Chen Z.Y., Mauk M., Hong K.-S., Li M.Y., Yang S., et al. Self-actuated, thermo-responsive hydrogel valves for lab on a chip. Biomed Microdevices 7 4 (2005) 313-322
    • (2005) Biomed Microdevices , vol.7 , Issue.4 , pp. 313-322
    • Wang, J.1    Chen, Z.Y.2    Mauk, M.3    Hong, K.-S.4    Li, M.Y.5    Yang, S.6
  • 90
    • 33644842733 scopus 로고    scopus 로고
    • A disposable microfluidic cassette for DNA amplification and detection
    • Wang J., Chen Z.Y., Corstjens P.L.A.M., Mauk M.G., and Bau H.H. A disposable microfluidic cassette for DNA amplification and detection. Lab Chip 6 (2006) 46-53
    • (2006) Lab Chip , vol.6 , pp. 46-53
    • Wang, J.1    Chen, Z.Y.2    Corstjens, P.L.A.M.3    Mauk, M.G.4    Bau, H.H.5
  • 91
  • 93
    • 13244251242 scopus 로고    scopus 로고
    • Micropumps - past, progress and future prospects
    • Woias P. Micropumps - past, progress and future prospects. Sens Actuators B Chem 105 (2005) 28-38
    • (2005) Sens Actuators B Chem , vol.105 , pp. 28-38
    • Woias, P.1
  • 94
    • 0034272872 scopus 로고    scopus 로고
    • Semi-disposable microvalves for use with microfabricated devices or microchips
    • Yuen P.K., Kricka L.J., and Wilding P. Semi-disposable microvalves for use with microfabricated devices or microchips. J Micromech Microeng 10 (2000) 401-409
    • (2000) J Micromech Microeng , vol.10 , pp. 401-409
    • Yuen, P.K.1    Kricka, L.J.2    Wilding, P.3
  • 97
    • 33645844551 scopus 로고    scopus 로고
    • PCR microfluidic devices for DNA amplification
    • Zhang C.S., Xu J.L., Ma W.L., and Zheng W.L. PCR microfluidic devices for DNA amplification. Biotech Adv 24 3 (2006) 243-284
    • (2006) Biotech Adv , vol.24 , Issue.3 , pp. 243-284
    • Zhang, C.S.1    Xu, J.L.2    Ma, W.L.3    Zheng, W.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.