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Volumn 102, Issue 3, 2007, Pages 741-752

The lack of CB1 receptors prevents neuroadapatations of both NMDA and GABAA receptors after chronic ethanol exposure

Author keywords

Cannabinoid; CB1 receptor; Chronic ethanol; Knockout; NMDA

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CANNABINOID 1 RECEPTOR; DIAZEPAM; DIZOCILPINE; ENDOCANNABINOID; MUSCIMOL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PENTOBARBITAL; TRITIUM;

EID: 34447298598     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04577.x     Document Type: Article
Times cited : (21)

References (64)
  • 2
  • 3
    • 0034672570 scopus 로고    scopus 로고
    • Stimulation of cannabinoid receptor agonist 2-arachidonylglycerol by chronic ethanol and its modulation by specific neuromodulators in cerebellar granule neurons
    • Basavarajappa B. S., Saito M., Cooper T. B. Hungund B. L. (2000) Stimulation of cannabinoid receptor agonist 2-arachidonylglycerol by chronic ethanol and its modulation by specific neuromodulators in cerebellar granule neurons. Biochim. Biophys. Acta 1535, 78 86.
    • (2000) Biochim. Biophys. Acta , vol.1535 , pp. 78-86
    • Basavarajappa, B.S.1    Saito, M.2    Cooper, T.B.3    Hungund, B.L.4
  • 4
    • 12244313878 scopus 로고    scopus 로고
    • Chronic ethanol inhibits the anandamide transport and increases extracellular anandamide levels in cerebellar granule neurons
    • Basavarajappa B. S., Saito M., Cooper T. B. Hungund B. L. (2003) Chronic ethanol inhibits the anandamide transport and increases extracellular anandamide levels in cerebellar granule neurons. Eur. J. Pharmacol. 466, 73 83.
    • (2003) Eur. J. Pharmacol. , vol.466 , pp. 73-83
    • Basavarajappa, B.S.1    Saito, M.2    Cooper, T.B.3    Hungund, B.L.4
  • 5
    • 33646701449 scopus 로고    scopus 로고
    • Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice
    • Basavarajappa B. S., Yalamanchili R., Cravatt B. F., Cooper T. B. Hungund B. L. (2006) Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice. Neuropharmacology 50, 834 844.
    • (2006) Neuropharmacology , vol.50 , pp. 834-844
    • Basavarajappa, B.S.1    Yalamanchili, R.2    Cravatt, B.F.3    Cooper, T.B.4    Hungund, B.L.5
  • 6
    • 1642364577 scopus 로고    scopus 로고
    • Differential effects of delta-9-tetrahydrocannabinol and methanandamide on operant behavior in CB1 knockout and wild type mice
    • Baskfield C. Y., Martin B. R. Wiley J. L. (2004) Differential effects of delta-9-tetrahydrocannabinol and methanandamide on operant behavior in CB1 knockout and wild type mice. J. Pharmacol. Exp. Ther. 309, 86 91.
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , pp. 86-91
    • Baskfield, C.Y.1    Martin, B.R.2    Wiley, J.L.3
  • 8
    • 0032407274 scopus 로고    scopus 로고
    • Genetic association of a GABAA receptor 2 subunit variant with severity of acute physiological dependence on alcohol
    • Buck K. J. Hood H. M. (1998) Genetic association of a GABAA receptor 2 subunit variant with severity of acute physiological dependence on alcohol. Mamm. Genome 9, 975 978.
    • (1998) Mamm. Genome , vol.9 , pp. 975-978
    • Buck, K.J.1    Hood, H.M.2
  • 9
    • 0036748948 scopus 로고    scopus 로고
    • SR141716, a central cannabinoid (CB(1)) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats
    • Cohen C., Perrault G., Voltz C., Steinberg R. Soubrie P. (2002) SR141716, a central cannabinoid (CB(1)) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats. Behav. Pharmacol. 13, 451 463.
    • (2002) Behav. Pharmacol. , vol.13 , pp. 451-463
    • Cohen, C.1    Perrault, G.2    Voltz, C.3    Steinberg, R.4    Soubrie, P.5
  • 10
    • 0031926412 scopus 로고    scopus 로고
    • Reduction of voluntary ethanol intake in ethanol-preferring sP rats by the cannabinoid antagonist SR-141716
    • Colombo G., Agabio R. Fa M. (1998) Reduction of voluntary ethanol intake in ethanol-preferring sP rats by the cannabinoid antagonist SR-141716. Alcohol Alcohol. 33, 126 130.
    • (1998) Alcohol Alcohol. , vol.33 , pp. 126-130
    • Colombo, G.1    Agabio, R.2    Fa, M.3
  • 12
    • 4344633808 scopus 로고    scopus 로고
    • Pharmacogenetic studies of alcohol self-administration and withdrawal
    • Crabbe J. C. Phillips T.J. (2004) Pharmacogenetic studies of alcohol self-administration and withdrawal. Psychopharmacology (Berl.) 174, 539 560.
    • (2004) Psychopharmacology (Berl.) , vol.174 , pp. 539-560
    • Crabbe, J.C.1    Phillips, T.J.2
  • 14
    • 0027366620 scopus 로고
    • Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-d-aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats
    • Criswell H. E., Johnson K. B., Mueller R. A. Breese G. R. (1993) Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-d-aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats. J. Pharmacol. Exp. Ther. 265, 1001 1010.
    • (1993) J. Pharmacol. Exp. Ther. , vol.265 , pp. 1001-1010
    • Criswell, H.E.1    Johnson, K.B.2    Mueller, R.A.3    Breese, G.R.4
  • 15
    • 4444321237 scopus 로고    scopus 로고
    • Imbalance between neuroexcitatory and neuroinhibitory amino acids causes craving for ethanol
    • De Witte P. (2004) Imbalance between neuroexcitatory and neuroinhibitory amino acids causes craving for ethanol. Addict. Behav. 29, 1325 1339.
    • (2004) Addict. Behav. , vol.29 , pp. 1325-1339
    • De Witte, P.1
  • 16
    • 0032479880 scopus 로고    scopus 로고
    • Ethanol and neurotransmitter interactions-from molecular to integrative effects
    • Faingold C. L., N'Gouemo P. Riaz A. (1998) Ethanol and neurotransmitter interactions-from molecular to integrative effects. Prog. Neurobiol. 55, 509 535.
    • (1998) Prog. Neurobiol. , vol.55 , pp. 509-535
    • Faingold, C.L.1    N'Gouemo, P.2    Riaz, A.3
  • 17
    • 0344737031 scopus 로고    scopus 로고
    • Chronic ethanol ingestion facilitates N-methyl-d-aspartate receptor function and expression in rat lateral/basolateral amygdala neurons
    • Floyd D. W., Jung K. Y. McCool B. A. (2003) Chronic ethanol ingestion facilitates N-methyl-d-aspartate receptor function and expression in rat lateral/basolateral amygdala neurons. J. Pharmacol. Exp. Ther. 307, 1020 1029.
    • (2003) J. Pharmacol. Exp. Ther. , vol.307 , pp. 1020-1029
    • Floyd, D.W.1    Jung, K.Y.2    McCool, B.A.3
  • 18
    • 0032901227 scopus 로고    scopus 로고
    • The motivation for beer in rats: Effects of ritanserin, naloxone and SR 141716
    • Gallate J. E. McGregor I. S. (1999) The motivation for beer in rats: effects of ritanserin, naloxone and SR 141716. Psychopharmacology (Berl.) 142, 302 308.
    • (1999) Psychopharmacology (Berl.) , vol.142 , pp. 302-308
    • Gallate, J.E.1    McGregor, I.S.2
  • 19
    • 0032952420 scopus 로고    scopus 로고
    • Increased motivation for beer in rats following administration of a cannabinoid CB1 receptor agonist
    • Gallate J. E., Saharov T., Mallet P. E. McGregor I. S. (1999) Increased motivation for beer in rats following administration of a cannabinoid CB1 receptor agonist. Eur. J. Pharmacol. 370, 233 240.
    • (1999) Eur. J. Pharmacol. , vol.370 , pp. 233-240
    • Gallate, J.E.1    Saharov, T.2    Mallet, P.E.3    McGregor, I.S.4
  • 20
    • 20444398090 scopus 로고    scopus 로고
    • Endocannabinoid signaling system and brain reward: Emphasis on dopamine
    • Gardner E. L. (2005) Endocannabinoid signaling system and brain reward: emphasis on dopamine. Pharmacol. Biochem. Behav. 81, 263 284.
    • (2005) Pharmacol. Biochem. Behav. , vol.81 , pp. 263-284
    • Gardner, E.L.1
  • 21
    • 0025731207 scopus 로고
    • Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal
    • Gulya K., Grant K. A., Valverius P., Hoffman P. L. Tabakoff B. (1991) Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal. Brain Res. 547, 129 134.
    • (1991) Brain Res. , vol.547 , pp. 129-134
    • Gulya, K.1    Grant, K.A.2    Valverius, P.3    Hoffman, P.L.4    Tabakoff, B.5
  • 23
    • 0031693278 scopus 로고    scopus 로고
    • The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions
    • Hodge C. W. Cox A. A. (1998) The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions. Psychopharmacology 139, 95 107.
    • (1998) Psychopharmacology , vol.139 , pp. 95-107
    • Hodge, C.W.1    Cox, A.A.2
  • 24
    • 0029609840 scopus 로고
    • GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats
    • Hodge C. W., Chappelle A. M. Samson H. H. (1995) GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats. Alcohol. Clin. Exp. Res. 19, 1486 1493.
    • (1995) Alcohol. Clin. Exp. Res. , vol.19 , pp. 1486-1493
    • Hodge, C.W.1    Chappelle, A.M.2    Samson, H.H.3
  • 25
    • 12344282798 scopus 로고    scopus 로고
    • CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors
    • Houchi H., Babovic D., Pierrefiche O., Ledent C., Daoust M. Naassila M. (2005) CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors. Neuropsychopharmacology 30, 339 349.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 339-349
    • Houchi, H.1    Babovic, D.2    Pierrefiche, O.3    Ledent, C.4    Daoust, M.5    Naassila, M.6
  • 27
    • 0037317155 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens
    • Hungund B. L., Szakall I., Adam A., Basavarajappa B. S. Vadasz C. (2003) Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens. J. Neurochem. 84, 698 704.
    • (2003) J. Neurochem. , vol.84 , pp. 698-704
    • Hungund, B.L.1    Szakall, I.2    Adam, A.3    Basavarajappa, B.S.4    Vadasz, C.5
  • 28
    • 0029665318 scopus 로고    scopus 로고
    • GABAA receptor pharmacology
    • Johnston G. A. R. (1996) GABAA receptor pharmacology. Pharmacol. Ther. 69, 173 198.
    • (1996) Pharmacol. Ther. , vol.69 , pp. 173-198
    • Johnston, G.A.R.1
  • 30
    • 0033555839 scopus 로고    scopus 로고
    • Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
    • Ledent C., Valverde O., Cossu G. et al. (1999) Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283, 401 404.
    • (1999) Science , vol.283 , pp. 401-404
    • Ledent, C.1    Valverde, O.2    Cossu, G.3
  • 31
    • 0034613173 scopus 로고    scopus 로고
    • Molecular and neuronal substrate for the selective attenuation of anxiety
    • Low K., Crestani F., Keist R. et al. (2000) Molecular and neuronal substrate for the selective attenuation of anxiety. Science 290, 131 134.
    • (2000) Science , vol.290 , pp. 131-134
    • Low, K.1    Crestani, F.2    Keist, R.3
  • 33
    • 33645982868 scopus 로고    scopus 로고
    • Involvement of the endocannabinoid system in drug addiction
    • Maldonado R., Valverde O. Berrendero F. (2006) Involvement of the endocannabinoid system in drug addiction. Trends Neurosci. 29, 225 232.
    • (2006) Trends Neurosci. , vol.29 , pp. 225-232
    • Maldonado, R.1    Valverde, O.2    Berrendero, F.3
  • 34
    • 0344417904 scopus 로고    scopus 로고
    • Ifenprodil influences changes in mouse behaviour related to acute and chronic ethanol administration
    • Malinowska B., Napiorkowska-Pawlak D., Pawlak R., Buczko W. Gothert M. (1999) Ifenprodil influences changes in mouse behaviour related to acute and chronic ethanol administration. Eur. J. Pharmacol. 377, 13 19.
    • (1999) Eur. J. Pharmacol. , vol.377 , pp. 13-19
    • Malinowska, B.1    Napiorkowska-Pawlak, D.2    Pawlak, R.3    Buczko, W.4    Gothert, M.5
  • 35
    • 0034108997 scopus 로고    scopus 로고
    • Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype
    • McKernan R. M., Rosahl T. W., Reynolds D. S. et al. (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype. Nat. Neurosci. 3, 587 592.
    • (2000) Nat. Neurosci. , vol.3 , pp. 587-592
    • McKernan, R.M.1    Rosahl, T.W.2    Reynolds, D.S.3
  • 36
    • 0037666070 scopus 로고    scopus 로고
    • Cannabis and alcohol - A close friendship
    • Mechoulam R. Parker L. (2003) Cannabis and alcohol - a close friendship. Trends Pharmacol. Sci. 24, 266 268.
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 266-268
    • Mechoulam, R.1    Parker, L.2
  • 37
    • 0032517172 scopus 로고    scopus 로고
    • Chronic ethanol administration alters the modulatory effect of 5alpha-pregnan-3alpha-ol-20-one on the binding characteristics of various radioligands of GABAA receptors
    • Mehta A. K. Ticku M. K. (1998) Chronic ethanol administration alters the modulatory effect of 5alpha-pregnan-3alpha-ol-20-one on the binding characteristics of various radioligands of GABAA receptors. Brain Res. 805, 88 94.
    • (1998) Brain Res. , vol.805 , pp. 88-94
    • Mehta, A.K.1    Ticku, M.K.2
  • 38
    • 11144336034 scopus 로고    scopus 로고
    • Effect of chronic administration of ethanol on GABAA receptor assemblies derived from alpha2-, alpha3-, beta2- and gamma2-subunits in the rat cerebral cortex
    • Mehta A. K. Ticku M. K. (2005) Effect of chronic administration of ethanol on GABAA receptor assemblies derived from alpha2-, alpha3-, beta2- and gamma2-subunits in the rat cerebral cortex. Brain Res. 1031, 134 137.
    • (2005) Brain Res. , vol.1031 , pp. 134-137
    • Mehta, A.K.1    Ticku, M.K.2
  • 39
    • 0036316216 scopus 로고    scopus 로고
    • Effect of prenatal and postnatal ethanol exposure on the developmental profile of mRNAs encoding NMDA receptor subunits in rat hippocampus
    • Naassila M. Daoust M. (2002) Effect of prenatal and postnatal ethanol exposure on the developmental profile of mRNAs encoding NMDA receptor subunits in rat hippocampus. J. Neurochem. 80, 850 860.
    • (2002) J. Neurochem. , vol.80 , pp. 850-860
    • Naassila, M.1    Daoust, M.2
  • 40
    • 0036897362 scopus 로고    scopus 로고
    • Low ethanol sensitivity and increased ethanol consumption in mice lacking adenosine A2A receptors
    • Naassila M., Ledent C. Daoust M. (2002) Low ethanol sensitivity and increased ethanol consumption in mice lacking adenosine A2A receptors. J. Neurosci. 22, 1087 1093.
    • (2002) J. Neurosci. , vol.22 , pp. 1087-1093
    • Naassila, M.1    Ledent, C.2    Daoust, M.3
  • 41
    • 0347480441 scopus 로고    scopus 로고
    • Decreased alcohol self-administration and increased alcohol sensitivity and withdrawal in CB1 receptor knockout mice
    • Naassila M., Pierrefiche O., Ledent C. Daoust M. (2004) Decreased alcohol self-administration and increased alcohol sensitivity and withdrawal in CB1 receptor knockout mice. Neuropharmacology 46, 243 253.
    • (2004) Neuropharmacology , vol.46 , pp. 243-253
    • Naassila, M.1    Pierrefiche, O.2    Ledent, C.3    Daoust, M.4
  • 42
    • 0028983843 scopus 로고
    • [3H]MK-801 binding in various brain regions of rat lines selected for differential alcohol sensitivity
    • Nakki R., Wong G. Korpi E. R. (1995) [3H]MK-801 binding in various brain regions of rat lines selected for differential alcohol sensitivity. Alcohol 12, 335 340.
    • (1995) Alcohol , vol.12 , pp. 335-340
    • Nakki, R.1    Wong, G.2    Korpi, E.R.3
  • 43
    • 0028855721 scopus 로고
    • Effect of ethanol treatment on rate and equilibrium constants for [3H] muscimol binding to rat brain membranes: Alteration of two affinity states of the GABAA receptor
    • Negro M., Chinchetru M. A., Fernandez A. Calvo P. (1995) Effect of ethanol treatment on rate and equilibrium constants for [3H] muscimol binding to rat brain membranes: alteration of two affinity states of the GABAA receptor. J. Neurochem. 64, 1379 1389.
    • (1995) J. Neurochem. , vol.64 , pp. 1379-1389
    • Negro, M.1    Chinchetru, M.A.2    Fernandez, A.3    Calvo, P.4
  • 44
    • 27844583905 scopus 로고    scopus 로고
    • Involvement of the endogenous cannabinoid system in the effects of alcohol in the mesolimbic reward circuit: Electrophysiological evidence in vivo
    • Perra S., Pillolla G., Melis M., Muntoni A. L., Gessa G. L. Pistis M. (2005) Involvement of the endogenous cannabinoid system in the effects of alcohol in the mesolimbic reward circuit: electrophysiological evidence in vivo. Psychopharmacology (Berl.) 183, 368 377.
    • (2005) Psychopharmacology (Berl.) , vol.183 , pp. 368-377
    • Perra, S.1    Pillolla, G.2    Melis, M.3    Muntoni, A.L.4    Gessa, G.L.5    Pistis, M.6
  • 45
    • 0038548401 scopus 로고    scopus 로고
    • Overeating, alcohol and sucrose consumption decrease in CB1 receptor deleted mice
    • Poncelet M., Maruani J., Calassi R. Soubrie P. (2003) Overeating, alcohol and sucrose consumption decrease in CB1 receptor deleted mice. Neurosci. Lett. 343, 216 218.
    • (2003) Neurosci. Lett. , vol.343 , pp. 216-218
    • Poncelet, M.1    Maruani, J.2    Calassi, R.3    Soubrie, P.4
  • 49
    • 0141569516 scopus 로고    scopus 로고
    • Sedation and anesthesia mediated by distinct GABAA receptor isoforms
    • Reynolds D. S., Rosahl T. W. Cirone J. (2003) Sedation and anesthesia mediated by distinct GABAA receptor isoforms. J. Neurosci. 23, 8608 8617.
    • (2003) J. Neurosci. , vol.23 , pp. 8608-8617
    • Reynolds, D.S.1    Rosahl, T.W.2    Cirone, J.3
  • 50
    • 11844289551 scopus 로고    scopus 로고
    • Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice
    • Rhodes J. S., Best K., Belknap J. K., Finn D. A. Crabbe J. C. (2005) Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice. Physiol. Behav. 84, 53 63.
    • (2005) Physiol. Behav. , vol.84 , pp. 53-63
    • Rhodes, J.S.1    Best, K.2    Belknap, J.K.3    Finn, D.A.4    Crabbe, J.C.5
  • 51
    • 0032794966 scopus 로고    scopus 로고
    • Cannabinoid receptor antagonist SR141716A decreases operant ethanol self administration in rats exposed to ethanol-vapor chambers
    • Rodriguez de Fonseca F., Roberts A. J., Bilbao A. Koob G. F. (1999) Cannabinoid receptor antagonist SR141716A decreases operant ethanol self administration in rats exposed to ethanol-vapor chambers. Acta Pharmacol. Sin. 20, 1109 1114.
    • (1999) Acta Pharmacol. Sin. , vol.20 , pp. 1109-1114
    • Rodriguez De Fonseca, F.1    Roberts, A.J.2    Bilbao, A.3    Koob, G.F.4
  • 52
    • 0029030812 scopus 로고
    • Block of the N-methyl-d-aspartate receptor by phencyclidine-like drugs is influenced by alternative splicing
    • Rodriguez-Paz J. M., Anantharam V. Treistman S. N. (1995) Block of the N-methyl-d-aspartate receptor by phencyclidine-like drugs is influenced by alternative splicing. Neurosci. Lett. 190, 147 150.
    • (1995) Neurosci. Lett. , vol.190 , pp. 147-150
    • Rodriguez-Paz, J.M.1    Anantharam, V.2    Treistman, S.N.3
  • 53
    • 3242776084 scopus 로고    scopus 로고
    • Signaling cascades regulating NMDA receptor sensitivity to ethanol
    • Ron D. (2004) Signaling cascades regulating NMDA receptor sensitivity to ethanol. Neuroscientist 10, 325 336.
    • (2004) Neuroscientist , vol.10 , pp. 325-336
    • Ron, D.1
  • 55
    • 0037123855 scopus 로고    scopus 로고
    • Blockade by the cannabinoid CB(1) receptor antagonist, SR 141716, of alcohol deprivation effect in alcohol-preferring rats
    • Serra S., Brunetti G., Pani M., Vacca G., Carai M. A., Gessa G. L. Colombo G. (2002) Blockade by the cannabinoid CB(1) receptor antagonist, SR 141716, of alcohol deprivation effect in alcohol-preferring rats. Eur. J. Pharmacol. 443, 95 97.
    • (2002) Eur. J. Pharmacol. , vol.443 , pp. 95-97
    • Serra, S.1    Brunetti, G.2    Pani, M.3    Vacca, G.4    Carai, M.A.5    Gessa, G.L.6    Colombo, G.7
  • 58
    • 1842664350 scopus 로고    scopus 로고
    • Impaired action of anxiolytic drugs in mice deficient in cannabinoid CB1 receptors
    • Urigüen L., Pérez-Rial S., Ledent C., Palomo T. Manzanares J. (2004) Impaired action of anxiolytic drugs in mice deficient in cannabinoid CB1 receptors. Neuropharmacology 46, 966 973.
    • (2004) Neuropharmacology , vol.46 , pp. 966-973
    • Urigüen, L.1    Pérez-Rial, S.2    Ledent, C.3    Palomo, T.4    Manzanares, J.5
  • 59
    • 27644581965 scopus 로고    scopus 로고
    • Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice
    • Urigüen L., Berrendero F., Ledent C., Maldonado R. Manzanares J. (2005) Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice. Eur. J. Neurosci. 22, 2106 2110.
    • (2005) Eur. J. Neurosci. , vol.22 , pp. 2106-2110
    • Urigüen, L.1    Berrendero, F.2    Ledent, C.3    Maldonado, R.4    Manzanares, J.5
  • 60
    • 0036015096 scopus 로고    scopus 로고
    • Evaluation of CB1 receptor knockout mice in the Morris water maze
    • Varvel S. A. Lichtman A. H. (2002) Evaluation of CB1 receptor knockout mice in the Morris water maze. J. Pharmacol. Exp. Ther. 301, 915 924.
    • (2002) J. Pharmacol. Exp. Ther. , vol.301 , pp. 915-924
    • Varvel, S.A.1    Lichtman, A.H.2
  • 61
    • 0031787418 scopus 로고    scopus 로고
    • Differences in NMDA receptor antagonist-induced locomotor activity and [3H]MK-801 binding sites in short-sleep and long-sleep mice
    • Velardo M. J., Simpson V. J. Zahniser N. R. (1998) Differences in NMDA receptor antagonist-induced locomotor activity and [3H]MK-801 binding sites in short-sleep and long-sleep mice. Alcohol. Clin. Exp. Res. 22, 1509 1515.
    • (1998) Alcohol. Clin. Exp. Res. , vol.22 , pp. 1509-1515
    • Velardo, M.J.1    Simpson, V.J.2    Zahniser, N.R.3
  • 62
    • 33749536387 scopus 로고    scopus 로고
    • Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system
    • Vinod K. Y., Yalamanchili R., Xie S., Cooper T. B. Hungund B. L. (2006) Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system. Neurochem. Int. 49, 619 625.
    • (2006) Neurochem. Int. , vol.49 , pp. 619-625
    • Vinod, K.Y.1    Yalamanchili, R.2    Xie, S.3    Cooper, T.B.4    Hungund, B.L.5
  • 63
    • 0037417989 scopus 로고    scopus 로고
    • Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice
    • Wang L., Liu J., Harvey-White J., Zimmer A. Kunos G. (2003) Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice. Proc. Natl Acad. Sci. USA 100, 1393 1398.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 1393-1398
    • Wang, L.1    Liu, J.2    Harvey-White, J.3    Zimmer, A.4    Kunos, G.5
  • 64
    • 0030779570 scopus 로고    scopus 로고
    • Key amino acids in the α subunit of the γ-aminobutyric acid a receptor that determine ligand binding and modulation at the benzodiazepine site
    • Wingrove P. B., Thompson S. A., Wafford K. A. Whiting P. J. (1997) Key amino acids in the α subunit of the γ-aminobutyric acid A receptor that determine ligand binding and modulation at the benzodiazepine site. Mol. Pharmacol. 52, 874 881.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 874-881
    • Wingrove, P.B.1    Thompson, S.A.2    Wafford, K.A.3    Whiting, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.