BRCA1 activates a G2-M cell cycle checkpoint following 6-thioguanine-induced DNA mismatch damage

Cancer Research

Volumn 67, Issue 13, 2007, Pages 6286-6292

  Yamane, Kazuhiko ^a,b,c   Schupp, Jane E ^a   Kinsella, Timothy J ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BRCA1 PROTEIN; CHECKPOINT KINASE 1; COMPLEMENTARY DNA; IODODEOXYCYTIDINE; PHOSPHODIESTERASE I; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; SMALL INTERFERING RNA; TIOGUANINE; BRCA1 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; DNA STRAND BREAKAGE; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MISMATCH REPAIR; PRIORITY JOURNAL; BASE MISPAIRING; BIOSYNTHESIS; CELL CYCLE; CELL DIVISION; COMET ASSAY; CONFOCAL MICROSCOPY; MITOSIS; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

BASE PAIR MISMATCH; BRCA1 PROTEIN; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; COMET ASSAY; DNA MISMATCH REPAIR; G2 PHASE; HUMANS; MICROSCOPY, CONFOCAL; MITOSIS; MUTATION; PHOSPHORYLATION; THIOGUANINE; TRANSFECTION;

EID: 34447129610     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-2205     Document Type: Article

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