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Volumn 8, Issue 4, 2004, Pages 335-353

Development of ligand-targeted liposomes for cancer therapy

Author keywords

Immunoliposomes; Ligand directed therapeutics; Ligand targeted liposomes; Receptor mediated endocytosis; Receptor targeted liposomes; Targeted drug delivery

Indexed keywords

ACRIDINE; ALEMTUZUMAB; ANTINEOPLASTIC AGENT; ANTISENSE OLIGODEOXYNUCLEOTIDE; ARGINYLGLYCYLASPARTIC ACID; CETUXIMAB; CISPLATIN; CYTARABINE; CYTARABINE DERIVATIVE; DAUNORUBICIN; DOXORUBICIN; DRUG CARRIER; EPIRUBICIN; EPITOPE; EVACET; GEMTUZUMAB OZOGAMICIN; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; IBRITUMOMAB; IBRITUMOMAB TIUXETAN; IMMUNOLIPOSOME; LIGAND; LIPOSOME; LURTOTECAN; MITOXANTRONE; MYOLTARG; NAVELBINE; OLIGONUCLEOTIDE; PLASMID DNA; RETINOID DERIVATIVE; RITUXIMAB; TRASTUZUMAB; UNINDEXED DRUG; VINCRISTINE;

EID: 4344646266     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.8.4.335     Document Type: Review
Times cited : (146)

References (133)
  • 2
    • 0031055830 scopus 로고    scopus 로고
    • Phase II study of liposomal doxorubicin in refactory ovarian cancer: Antitumor activity and toxicity modification by liposomal encapsulation
    • MUGGIA FM, HAINSWORTH JD, JEFFERS S et al.: Phase II study of liposomal doxorubicin in refactory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation. J. Clin. Oncol. (1997) 15:987-993.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 987-993
    • Muggia, F.M.1    Hainsworth, J.D.2    Jeffers, S.3
  • 3
    • 0035139492 scopus 로고    scopus 로고
    • Caelyx (stealth liposomal doxorubicin) in the treatment of advanced breast cancer
    • RANSON MR, CHEESEMAN S, WHITE S, MARGISON J: Caelyx (stealth liposomal doxorubicin) in the treatment of advanced breast cancer. Crit. Rev. Oncol. Hematol. (2001) 37:115-120.
    • (2001) Crit. Rev. Oncol. Hematol. , vol.37 , pp. 115-120
    • Ranson, M.R.1    Cheeseman, S.2    White, S.3    Margison, J.4
  • 4
    • 0035013358 scopus 로고    scopus 로고
    • The clinical utility of liposomal doxorubicin in recurrent ovarian cancer
    • CAMPOS SM, PENSON RT, MAYS AR et al.: The clinical utility of liposomal doxorubicin in recurrent ovarian cancer. Gynecol. Oncol. (2001) 81:206-212.
    • (2001) Gynecol. Oncol. , vol.81 , pp. 206-212
    • Campos, S.M.1    Penson, R.T.2    Mays, A.R.3
  • 5
    • 0035879099 scopus 로고    scopus 로고
    • Recurrent epithelia] ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan
    • GORDON AN, FLEAGLE JT, GUTHRIE D et al.: Recurrent epithelia] ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J. Clin. Oncol. (2001) 19:3312-3322.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3312-3322
    • Gordon, A.N.1    Fleagle, J.T.2    Guthrie, D.3
  • 6
    • 0035165412 scopus 로고    scopus 로고
    • Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: Analysis of toxicities and predictors of outcome
    • SAFRA T, GROSHEN S, JEFFERS S et al.: Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: analysis of toxicities and predictors of outcome. Cancer (2001) 91:90-100.
    • (2001) Cancer , vol.91 , pp. 90-100
    • Safra, T.1    Groshen, S.2    Jeffers, S.3
  • 7
    • 0031036426 scopus 로고    scopus 로고
    • Efficacy of pegylated-liposomal doxorubicin in the treatment of AIDS-related Kaposi's sarcoma after failure of standard chemotherapy
    • NORTHFELT DW, DEZUBE BJ, THOMMES JA et al.: Efficacy of pegylated-liposomal doxorubicin in the treatment of AIDS-related Kaposi's sarcoma after failure of standard chemotherapy. J. Clin. Oncol. (1997) 15:653-659.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 653-659
    • Northfelt, D.W.1    Dezube, B.J.2    Thommes, J.A.3
  • 8
    • 0035986759 scopus 로고    scopus 로고
    • Cyclophosphamide, pegylated liposomal doxorubicin (Caelyx), vincristine and prednisone (CCOP) in elderly patients with diffuse large B-cell lymphoma: Results from a prospective Phase II study
    • MARTINO R, PEREA G, CABALLERO MD et al.: Cyclophosphamide, pegylated liposomal doxorubicin (Caelyx), vincristine and prednisone (CCOP) in elderly patients with diffuse large B-cell lymphoma: results from a prospective Phase II study. Haematologica (2002) 87:822-827.
    • (2002) Haematologica , vol.87 , pp. 822-827
    • Martino, R.1    Perea, G.2    Caballero, M.D.3
  • 9
    • 0042388408 scopus 로고    scopus 로고
    • Multicenter study of pegylated liposomal doxorubicin in patients with cutaneous T-cell lymphoma
    • WOLLINA U, DRUMMER R, BROCKMEYER NH et al.: Multicenter study of pegylated liposomal doxorubicin in patients with cutaneous T-cell lymphoma. Cancer (2003) 98:993-1001.
    • (2003) Cancer , vol.98 , pp. 993-1001
    • Wollina, U.1    Drummer, R.2    Brockmeyer, N.H.3
  • 10
    • 9444258072 scopus 로고    scopus 로고
    • Randomized Phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma
    • GILL PS, WERNZ J, SCADDEN DT et al.: Randomized Phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma. J. Clin. Oncol. (1996) 14:2353-2364.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2353-2364
    • Gill, P.S.1    Wernz, J.2    Scadden, D.T.3
  • 11
    • 0035282073 scopus 로고    scopus 로고
    • Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer
    • BATIST G, RAMAKRISHNAN G, RAO CS et al.: Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer. J. Clin. Oncol. (2001) 19:1444-1454.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 1444-1454
    • Batist, G.1    Ramakrishnan, G.2    Rao, C.S.3
  • 12
    • 0033973456 scopus 로고    scopus 로고
    • Liposomal vincristine in relapsed non-Hodgkin's lymphomas: Early results of an ongoing Phase II trial
    • SARRIS AH, HAGEMEISTER F, ROMAGUERA J et al.: Liposomal vincristine in relapsed non-Hodgkin's lymphomas: early results of an ongoing Phase II trial. Ann. Oncol. (2000) 11:69-72.
    • (2000) Ann. Oncol. , vol.11 , pp. 69-72
    • Sarris, A.H.1    Hagemeister, F.2    Romaguera, J.3
  • 13
    • 0036499054 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of liposomal lurtotecan, NX 211: Urinary excretion predicts hematologic toxicity
    • KEHRER DF, BOS AM, VERWEIJ J et al.: Phase I and pharmacologic study of liposomal lurtotecan, NX 211: urinary excretion predicts hematologic toxicity. J. Clin. Oncol. (2002) 20:1222-1231.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 1222-1231
    • Kehrer, D.F.1    Bos, A.M.2    Verweij, J.3
  • 14
    • 0036781811 scopus 로고    scopus 로고
    • Ligand-targeted therapeutics in anticancer therapy
    • ALLEN TM: Ligand-targeted therapeutics in anticancer therapy. Nat Rev. Cancer (2002) 2:750-763.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 750-763
    • Allen, T.M.1
  • 15
    • 1642421130 scopus 로고    scopus 로고
    • Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment
    • NORMANNO N, BIANCO C, DE LUCA A, MAIELLO MR, SALOMON DS: Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr. Relat. Cancer (2003) 10:1-21.
    • (2003) Endocr. Relat. Cancer , vol.10 , pp. 1-21
    • Normanno, N.1    Bianco, C.2    De Luca, A.3    Maiello, M.R.4    Salomon, D.S.5
  • 17
    • 0001160175 scopus 로고    scopus 로고
    • In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma
    • LOPES DE MENEZES DE, PILARSKI LM, ALLEN TM: In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma. Cancer Res. (1998) 58:3320-3330.
    • (1998) Cancer Res. , vol.58 , pp. 3320-3330
    • Lopes, D.E.1    Menezes, D.E.2    Pilarski, L.M.3    Allen, T.M.4
  • 18
    • 0036554863 scopus 로고    scopus 로고
    • Anti-HER2 immunoliposomes: Enhanced efficacy attributable to targeted delivery
    • PARK JW, HONG K, KIRPOTIN DB et al.: Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery. Clin. Cancer Res. (2002) 8:1172-1181.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1172-1181
    • Park, J.W.1    Hong, K.2    Kirpotin, D.B.3
  • 19
    • 0027460861 scopus 로고
    • Antibody-targeted delivery of doxorubicin entrapped in sterically stabilized liposomes can eradicate lung cancer in mice
    • AHMAD I, LONGENECKER M, SAMUEL J, ALLEN TM: Antibody-targeted delivery of doxorubicin entrapped in sterically stabilized liposomes can eradicate lung cancer in mice. Cancer Res. (1993) 53:1484-1488.
    • (1993) Cancer Res. , vol.53 , pp. 1484-1488
    • Ahmad, I.1    Longenecker, M.2    Samuel, J.3    Allen, T.M.4
  • 21
    • 0034284335 scopus 로고    scopus 로고
    • Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil®) in metastatic breast carcinoma
    • LYASS O, UZIELY B, BEN-YOSEF R et al.: Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil®) in metastatic breast carcinoma. Cancer (2000) 89:1037-1047.
    • (2000) Cancer , vol.89 , pp. 1037-1047
    • Lyass, O.1    Uziely, B.2    Ben-Yosef, R.3
  • 22
    • 0032516078 scopus 로고    scopus 로고
    • Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
    • HOBBS SK, MONSKY WL, YUAN F et al.: Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc. Natl. Acad. Sci. USA (1998) 95:4607-4612.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 4607-4612
    • Hobbs, S.K.1    Monsky, W.L.2    Yuan, F.3
  • 23
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS
    • MATSUMURA Y, MAEDA H: A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res. (1986) 46:6387-6392.
    • (1986) Cancer Res. , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 24
    • 0026733476 scopus 로고
    • Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice
    • HUANG SK, LEE KD, HONG K, FRIEND DS, PAPAHADJOPOULOS D: Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice. Cancer Res. (1992) 52:5135-5143.
    • (1992) Cancer Res. , vol.52 , pp. 5135-5143
    • Huang, S.K.1    Lee, K.D.2    Hong, K.3    Friend, D.S.4    Papahadjopoulos, D.5
  • 25
    • 0030042023 scopus 로고    scopus 로고
    • Liposome longevity and stability in circulation: Effects on the in vivo delivery to tumors and therapeutic efficacy of encapsulated anthracyclines
    • GABIZON A, CHEMLA M, TZEMACH D, HOROWITZ AT, GOREN D: Liposome longevity and stability in circulation: effects on the in vivo delivery to tumors and therapeutic efficacy of encapsulated anthracyclines. J. Drug Target. (1996) 3:391-398.
    • (1996) J. Drug Target , vol.3 , pp. 391-398
    • Gabizon, A.1    Chemla, M.2    Tzemach, D.3    Horowitz, A.T.4    Goren, D.5
  • 27
    • 0038797831 scopus 로고    scopus 로고
    • Ligand-targeted liposomal anticancer drugs
    • SAPRA P, ALLEN TM: Ligand-targeted liposomal anticancer drugs. Prog. Lipid Res. (2003) 42:439-462.
    • (2003) Prog. Lipid Res. , vol.42 , pp. 439-462
    • Sapra, P.1    Allen, T.M.2
  • 28
    • 0035005359 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin: Metamorphosis of an old drug into a new form of chemotherapy
    • GABIZON AA: Pegylated liposomal doxorubicin: metamorphosis of an old drug into a new form of chemotherapy. Cancer Invest. (2001) 19:424-436.
    • (2001) Cancer Invest. , vol.19 , pp. 424-436
    • Gabizon, A.A.1
  • 30
    • 0027283498 scopus 로고
    • Stability of HER-2/neu expression over time and at multiple metastatic sites
    • NIEHANS GA, SINGLETON TP, DYKOSKI D, KIANG DT: Stability of HER-2/neu expression over time and at multiple metastatic sites. J. Natl. Cancer Inst. (1993) 85:1230-1235.
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1230-1235
    • Niehans, G.A.1    Singleton, T.P.2    Dykoski, D.3    Kiang, D.T.4
  • 31
    • 0031021149 scopus 로고    scopus 로고
    • Sterically stabilized anti-HER2 immunoliposomes: Design and targeting to human breast cancer cells in vitro
    • KIRPOTIN D, PARK JW, HONG K et al.: Sterically stabilized anti-HER2 immunoliposomes: design and targeting to human breast cancer cells in vitro. Biochemistry (1997) 36:66-75.
    • (1997) Biochemistry , vol.36 , pp. 66-75
    • Kirpotin, D.1    Park, J.W.2    Hong, K.3
  • 33
    • 0025359146 scopus 로고
    • Expression of the HERH2/neu proto-oncogene in normal human adult and fetal tissues
    • PRESS MF, CORDON-CARDO C, SLAMON DJ: Expression of the HERH2/neu proto-oncogene in normal human adult and fetal tissues. Oncogene (1990) 5:953-962.
    • (1990) Oncogene , vol.5 , pp. 953-962
    • Press, M.F.1    Cordon-Cardo, C.2    Slamon, D.J.3
  • 34
    • 0032562770 scopus 로고    scopus 로고
    • Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
    • ZHAO YY, SAWYER DR, BALIGA RR et al.: Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J. Biol. Chem. (1998) 273:10261-10269.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10261-10269
    • Zhao, Y.Y.1    Sawyer, D.R.2    Baliga, R.R.3
  • 35
  • 36
    • 0028301752 scopus 로고
    • Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines
    • ROSS JF, CHAUDHURI PK, RATNAM M: Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Cancer (1994) 73:2432-2443.
    • (1994) Cancer , vol.73 , pp. 2432-2443
    • Ross, J.F.1    Chaudhuri, P.K.2    Ratnam, M.3
  • 37
    • 0029828939 scopus 로고    scopus 로고
    • Targeting of stealth liposomes to erbB-2 (Her/2) receptor: In vitro and in vivo studies
    • GOREN D, HOROWITZ AT, ZALIPSKY S et al.: Targeting of stealth liposomes to erbB-2 (Her/2) receptor: in vitro and in vivo studies. Br. J. Cancer (1996) 74:1749-1756.
    • (1996) Br. J. Cancer , vol.74 , pp. 1749-1756
    • Goren, D.1    Horowitz, A.T.2    Zalipsky, S.3
  • 38
    • 0037115543 scopus 로고    scopus 로고
    • Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs
    • SAPRA P, ALLEN TM: Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs. Cancer Res. (2002) 62:7190-7194.
    • (2002) Cancer Res. , vol.62 , pp. 7190-7194
    • Sapra, P.1    Allen, T.M.2
  • 39
    • 0034031080 scopus 로고    scopus 로고
    • Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump
    • GOREN D, HOROWITZ AT, TZEMACH D et al.: Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump. Clin. Cancer Res. (2000) 6:1949-1957.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1949-1957
    • Goren, D.1    Horowitz, A.T.2    Tzemach, D.3
  • 40
    • 0034671316 scopus 로고    scopus 로고
    • Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice
    • SUGANO M, EGILMEZ NK, YOKOTA SJ et al.: Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice. Cancer Res. (2000) 60:6942-6949.
    • (2000) Cancer Res. , vol.60 , pp. 6942-6949
    • Sugano, M.1    Egilmez, N.K.2    Yokota, S.J.3
  • 41
    • 0033573873 scopus 로고    scopus 로고
    • Toward selection of internalizing antibodies from phage libraries
    • BECERRIL B, POUL MA, MARKS JD: Toward selection of internalizing antibodies from phage libraries. Biochem. Biophys. Res. Commun. (1999) 255:386-393.
    • (1999) Biochem. Biophys. Res. Commun. , vol.255 , pp. 386-393
    • Becerril, B.1    Poul, M.A.2    Marks, J.D.3
  • 42
    • 0034283551 scopus 로고    scopus 로고
    • Selection of tumor-specific internalizing human antibodies from phage libraries
    • POUL MA, BECERRIL B, NIELSEN UB, MORISSON P. MARKS JD: Selection of tumor-specific internalizing human antibodies from phage libraries. J. Mol. Biol. (2000) 301:1149-1161.
    • (2000) J. Mol. Biol. , vol.301 , pp. 1149-1161
    • Poul, M.A.1    Becerril, B.2    Nielsen, U.B.3    Morisson, P.4    Marks, J.D.5
  • 43
    • 0024346862 scopus 로고
    • Identification by monoclonal antibodies of an antigen shed by human bladder cancer cells
    • LIEBERT M, WEDEMEYER. GA, STEIN JA et al.: Identification by monoclonal antibodies of an antigen shed by human bladder cancer cells. Cancer Res. (1989) 49:6720-6726.
    • (1989) Cancer Res. , vol.49 , pp. 6720-6726
    • Liebert, M.1    Wedemeyer, G.A.2    Stein, J.A.3
  • 44
    • 0025145460 scopus 로고
    • Characterization of the shed form of the human tumor-associated glycoprotein (TAG-72) horn serous effusions of patients with different types of carcinomas
    • KATARI RS, FERNSTEN PD, SCHLOM J: Characterization of the shed form of the human tumor-associated glycoprotein (TAG-72) horn serous effusions of patients with different types of carcinomas. Cancer Res. (1990) 50:4885-4890.
    • (1990) Cancer Res. , vol.50 , pp. 4885-4890
    • Katari, R.S.1    Fernsten, P.D.2    Schlom, J.3
  • 45
    • 0025912062 scopus 로고
    • Monoclonal antibodies in diagnosis and therapy
    • WALDMANN TA: Monoclonal antibodies in diagnosis and therapy. Science (1991) 252:1657-1662.
    • (1991) Science , vol.252 , pp. 1657-1662
    • Waldmann, T.A.1
  • 46
    • 0031473207 scopus 로고    scopus 로고
    • Targeting of liposomes to solid tumors: The case of sterically stabilized anti-HER2 immunoliposomes
    • KIRPOTIN DB, PARK JW, HONG K et al.: Targeting of liposomes to solid tumors: the case of sterically stabilized anti-HER2 immunoliposomes. J. Liposome Res. (1997) 7:391-417.
    • (1997) J. Liposome Res. , vol.7 , pp. 391-417
    • Kirpotin, D.B.1    Park, J.W.2    Hong, K.3
  • 47
    • 0037135703 scopus 로고    scopus 로고
    • Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis
    • NIELSEN UB, KIRPOTIN DB, PICKERING EM et al.: Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis. Biochim. Biophys. Acta. (2002) 1591:109-118.
    • (2002) Biochim. Biophys. Acta , vol.1591 , pp. 109-118
    • Nielsen, U.B.1    Kirpotin, D.B.2    Pickering, E.M.3
  • 48
    • 1642556761 scopus 로고    scopus 로고
    • Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells
    • LIU B, CONRAD F, COOPERBERG MR, KIRPOTIN DB, MARKS JD: Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells. Cancer Res. (2004) 64:704-710.
    • (2004) Cancer Res. , vol.64 , pp. 704-710
    • Liu, B.1    Conrad, F.2    Cooperberg, M.R.3    Kirpotin, D.B.4    Marks, J.D.5
  • 49
    • 0029932762 scopus 로고    scopus 로고
    • Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer
    • LEE RJ, HUANG L: Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. J. Biol. Chem. (1996) 271:8481-8487.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8481-8487
    • Lee, R.J.1    Huang, L.2
  • 50
    • 0030895405 scopus 로고    scopus 로고
    • Transferrin-liposome-mediated p53 sensitization of squamous cell carcinoma of the head and neck to radiation in vitro
    • XU L, PIROLLO KF, CHANG EH: Transferrin-liposome-mediated p53 sensitization of squamous cell carcinoma of the head and neck to radiation in vitro. Hum. Gene Ther. (1997) 8:467-475.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 467-475
    • Xu, L.1    Pirollo, K.F.2    Chang, E.H.3
  • 51
    • 0035866799 scopus 로고    scopus 로고
    • Liposome-encapsulated doxorubicin targeted to CD44: A strategy to kill CD44-overexpressing tumor cells
    • ELIAZ RE, SZOKA FC Jr: Liposome-encapsulated doxorubicin targeted to CD44: a strategy to kill CD44-overexpressing tumor cells. Cancer Res. (2001) 61:2592-2601.
    • (2001) Cancer Res. , vol.61 , pp. 2592-2601
    • Eliaz, R.E.1    Szoka Jr., F.C.2
  • 52
    • 0029400887 scopus 로고
    • Peptide attachment to extremities of liposomal surface grafted PEG chains: Preparation of the long-circulating form of laminin pentapeptide, YIGSR
    • ZALIPSKYS, PUNTAMBEKAR. B, BOULIKAS P, ENGBERS CM, WOODLE MC: Peptide attachment to extremities of liposomal surface grafted PEG chains: preparation of the long-circulating form of laminin pentapeptide, YIGSR. Bioconjug. Chem. (1995) 6:705-708.
    • (1995) Bioconjug. Chem. , vol.6 , pp. 705-708
    • Zalipsky, S.1    Puntambekar, B.2    Boulikas, P.3    Engbers, C.M.4    Woodle, M.C.5
  • 53
    • 0035479680 scopus 로고    scopus 로고
    • A growth factor antagonist as a targeting agent for sterically stabilized liposomes in human small cell lung cancer
    • MOREIRA JN, HANSEN CB, GASPAR R, ALLEN TM: A growth factor antagonist as a targeting agent for sterically stabilized liposomes in human small cell lung cancer. Biochim. Biophys. Acta (2001) 1514:303-317.
    • (2001) Biochim. Biophys. Acta , vol.1514 , pp. 303-317
    • Moreira, J.N.1    Hansen, C.B.2    Gaspar, R.3    Allen, T.M.4
  • 54
    • 0032170107 scopus 로고    scopus 로고
    • Liposome-anchored vascular endothelial growth factor aptamers
    • WILLIS MC, COLLINS B, ZHANG T et al.: Liposome-anchored vascular endothelial growth factor aptamers. Bioconjug. Chem. (1998) 9:573-582.
    • (1998) Bioconjug. Chem. , vol.9 , pp. 573-582
    • Willis, M.C.1    Collins, B.2    Zhang, T.3
  • 55
    • 0141990623 scopus 로고    scopus 로고
    • Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin
    • SCHIFFELERS RM, KONING GA, TEN HAGEN TL et al.: Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin. J. Control. Release (2003) 91:115-122.
    • (2003) J. Control Release , vol.91 , pp. 115-122
    • Schiffelers, R.M.1    Koning, G.A.2    Ten Hagen, T.L.3
  • 56
    • 0037224431 scopus 로고    scopus 로고
    • Doxorubicin-loaded Fab' fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice
    • PASTORINO F, BRIGNOLE C, MARIMPIETRI D et al.: Doxorubicin-loaded Fab' fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice. Cancer Res. (2003) 63:86-92.
    • (2003) Cancer Res. , vol.63 , pp. 86-92
    • Pastorino, F.1    Brignole, C.2    Marimpietri, D.3
  • 57
    • 3242845082 scopus 로고
    • Immune clearance of liposomes inhibited by an anti-Fc receptor antibody in vivo
    • ARAGNOL D, LESERMAN LD: Immune clearance of liposomes inhibited by an anti-Fc receptor antibody in vivo. Proc. Natl. Acad. Sci. USA (1986) 83:2699-2703.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2699-2703
    • Aragnol, D.1    Leserman, L.D.2
  • 59
    • 13144261717 scopus 로고    scopus 로고
    • Efficient construction of a large nonimmune phage antibody library: The production of high-affinity human single-chain antibodies to protein antigens
    • SHEETS MD, AMERSDORFER P, FINNERN R et al.: Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. Proc. Natl. Acad. Sci. USA (1998) 95:6157-6162.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6157-6162
    • Sheets, M.D.1    Amersdorfer, P.2    Finnern, R.3
  • 60
    • 0034718615 scopus 로고    scopus 로고
    • Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity
    • BODER ET MIDELFORT KS, WITTRUP KD: Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity. Proc. Natl. Acad. Sci. USA (2000) 97:10701-10705.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10701-10705
    • Boder, E.T.1    Midelfort, K.S.2    Wittrup, K.D.3
  • 61
    • 0031729149 scopus 로고    scopus 로고
    • Liposomal drug formulations. Rationale for development and what we can expect in the future
    • ALLEN TM: Liposomal drug formulations. Rationale for development and what we can expect in the future. Drugs (1998) 56:747-756.
    • (1998) Drugs , vol.56 , pp. 747-756
    • Allen, T.M.1
  • 62
    • 0033957887 scopus 로고    scopus 로고
    • Role of drug release and liposome-mediated drug delivery in governing the therapeutic activity of liposomal mitoxantrone used to treat human A431 and LS 180 solid tumors
    • LIM HJ, MASIN D, MCINTOSH NL, MADDEN TD, BALLY MB: Role of drug release and liposome-mediated drug delivery in governing the therapeutic activity of liposomal mitoxantrone used to treat human A431 and LS 180 solid tumors. J. Pharmacol. Exp. Ther. (2000) 292:337-345.
    • (2000) J. Pharmacol. Exp. Ther. , vol.292 , pp. 337-345
    • Lim, H.J.1    Masin, D.2    Mcintosh, N.L.3    Madden, T.D.4    Bally, M.B.5
  • 63
    • 0028366109 scopus 로고
    • Novel taxol formulations: Preparation and characterization of taxol-containing liposomes
    • SHARMA A, STRAUBINGER RM: Novel taxol formulations: preparation and characterization of taxol-containing liposomes. Pharm. Res. (1994) 11:889-896.
    • (1994) Pharm. Res. , vol.11 , pp. 889-896
    • Sharma, A.1    Straubinger, R.M.2
  • 64
    • 0027162899 scopus 로고
    • Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing polyethylene glycol-derivatized phospholipid: Pharmacokinetic studies in rodents and dogs
    • GABIZON AA, BARENHOLZ Y, BIALER M: Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing polyethylene glycol-derivatized phospholipid: pharmacokinetic studies in rodents and dogs. Pharm. Res. (1993) 10:703-708.
    • (1993) Pharm. Res. , vol.10 , pp. 703-708
    • Gabizon, A.A.1    Barenholz, Y.2    Bialer, M.3
  • 65
    • 0028855939 scopus 로고
    • Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models
    • WEBB MS, HARASYM TO, MASIN D, BALLY MB, MAYER LD: Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models. Br. J. Cancer (1995) 72:896-904.
    • (1995) Br. J. Cancer , vol.72 , pp. 896-904
    • Webb, M.S.1    Harasym, T.O.2    Masin, D.3    Bally, M.B.4    Mayer, L.D.5
  • 66
    • 0031689827 scopus 로고    scopus 로고
    • Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): Effects on the pharmacokinetics of liposomal vincristine
    • WEBB MS, SAXON D, WONG FM et al.: Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): effects on the pharmacokinetics of liposomal vincristine. Biochim. Biophys. Acta (1998) 1372:272-282.
    • (1998) Biochim. Biophys. Acta , vol.1372 , pp. 272-282
    • Webb, M.S.1    Saxon, D.2    Wong, F.M.3
  • 67
    • 0028307261 scopus 로고
    • Influence of plasma on the osmotic sensitivity of large unilamellar vesicles prepared by extrusion
    • MUI BL, CULLIS PR, PRITCHARD PH, MADDEN TD: Influence of plasma on the osmotic sensitivity of large unilamellar vesicles prepared by extrusion. J. Biol. Chem. (1994) 269:7364-7370.
    • (1994) J. Biol. Chem. , vol.269 , pp. 7364-7370
    • Mui, B.L.1    Cullis, P.R.2    Pritchard, P.H.3    Madden, T.D.4
  • 69
    • 0030886615 scopus 로고    scopus 로고
    • Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles
    • CULLIS PR, HOPE MJ, BALLY MB et al.: Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles. Biochim. Biophys. Acta (1997) 1331:187-211.
    • (1997) Biochim. Biophys. Acta , vol.1331 , pp. 187-211
    • Cullis, P.R.1    Hope, M.J.2    Bally, M.B.3
  • 70
    • 0029265458 scopus 로고
    • Functionalized poly(ethlene glycol) for preparation of biologically relevant conjugates
    • ZALIPSKY S: Functionalized poly(ethlene glycol) for preparation of biologically relevant conjugates. Bioconjug. Chem. (1995) 6:150-165.
    • (1995) Bioconjug. Chem. , vol.6 , pp. 150-165
    • Zalipsky, S.1
  • 71
    • 0032496747 scopus 로고    scopus 로고
    • Clearance properties of liposomes involving conjugated proteins for targeting
    • HARASYM TO, BALLY MB, TARDI P: Clearance properties of liposomes involving conjugated proteins for targeting. Adv. Drug Deliv. Rev. (1998) 32:99-118.
    • (1998) Adv. Drug Deliv. Rev. , vol.32 , pp. 99-118
    • Harasym, T.O.1    Bally, M.B.2    Tardi, P.3
  • 72
    • 0028884966 scopus 로고
    • Attachment of antibodies to sterically stabilized liposomes: Evaluation, comparison and optimization of coupling procedures
    • HANSEN CB, KAO GY, MOASE EH, ZALIPSKY S, ALLEN TM: Attachment of antibodies to sterically stabilized liposomes: evaluation, comparison and optimization of coupling procedures. Biochim. Biophys. Acta (1995) 1239:133-144.
    • (1995) Biochim. Biophys. Acta , vol.1239 , pp. 133-144
    • Hansen, C.B.1    Kao, G.Y.2    Moase, E.H.3    Zalipsky, S.4    Allen, T.M.5
  • 73
    • 0029120094 scopus 로고
    • A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells
    • ALLEN TM, BRANDEIS E, HANSEN CB, KAO GY, ZALIPSKY S: A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells. Biochim. Biophys. Acta (1995) 1237:99-108.
    • (1995) Biochim. Biophys. Acta , vol.1237 , pp. 99-108
    • Allen, T.M.1    Brandeis, E.2    Hansen, C.B.3    Kao, G.Y.4    Zalipsky, S.5
  • 74
    • 0019874697 scopus 로고
    • Immunospecific targeting of liposomes to cells: A novel and efficient method for covalent attachment of Fab' fragments via disulfide bonds
    • MARTIN FJ, HUBBELL WL, PAPAHADJOPOULOS D: Immunospecific targeting of liposomes to cells: a novel and efficient method for covalent attachment of Fab' fragments via disulfide bonds. Biochemistry (1981) 20:4229-4238.
    • (1981) Biochemistry , vol.20 , pp. 4229-4238
    • Martin, F.J.1    Hubbell, W.L.2    Papahadjopoulos, D.3
  • 75
    • 0028053658 scopus 로고
    • Factors influencing the retention and chemical stability of poly(ethylene glycol)-lipid conjugates incorporated into large unilamellar vesicles
    • PARR MJ, ANSELL SM, CHOI LS, CULLIS PR: Factors influencing the retention and chemical stability of poly(ethylene glycol)-lipid conjugates incorporated into large unilamellar vesicles. Biochim. Biophys. Acta (1994) 1195:21-30.
    • (1994) Biochim. Biophys. Acta , vol.1195 , pp. 21-30
    • Parr, M.J.1    Ansell, S.M.2    Choi, L.S.3    Cullis, P.R.4
  • 76
    • 0028794831 scopus 로고
    • Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro
    • LEE RJ, LOW PS: Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitro. Biochim. Biophys. Acta (1995) 1233:134-144.
    • (1995) Biochim. Biophys. Acta , vol.1233 , pp. 134-144
    • Lee, R.J.1    Low, P.S.2
  • 77
    • 0028001056 scopus 로고
    • Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis
    • LEE RJ, LOW PS: Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis. J. Biol. Chem. (1994) 269:3198-3204.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3198-3204
    • Lee, R.J.1    Low, P.S.2
  • 78
    • 0033106119 scopus 로고    scopus 로고
    • Targeting folate receptor with folate linked to extremeties of poly(ethlene glycol)-grafted liposomes: In vitro studies
    • GABIZON A, HOROWITZ AT, GOREN D et al.: Targeting folate receptor with folate linked to extremeties of poly(ethlene glycol)-grafted liposomes: in vitro studies. Bioconjug. Chem. (1999) 10:289-298.
    • (1999) Bioconjug. Chem. , vol.10 , pp. 289-298
    • Gabizon, A.1    Horowitz, A.T.2    Goren, D.3
  • 79
    • 0027157735 scopus 로고
    • Specific targeting with poly(ethylene glycol)-modified liposomes: Coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times
    • BLUME G, CEVC G, CROMMELIN MD et al.: Specific targeting with poly(ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times. Biochim. Biophys. Acta (1993) 1149:180-184.
    • (1993) Biochim. Biophys. Acta , vol.1149 , pp. 180-184
    • Blume, G.1    Cevc, G.2    Crommelin, M.D.3
  • 80
    • 0028953974 scopus 로고
    • Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol)s conjugated at their distal terminals to monoclonal antibodies
    • MARUYAMA K, TAKIZAWA T, YUDA T et al.: Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol)s conjugated at their distal terminals to monoclonal antibodies. Biochim. Biophys. Acta (1995) 1234:74-80.
    • (1995) Biochim. Biophys. Acta , vol.1234 , pp. 74-80
    • Maruyama, K.1    Takizawa, T.2    Yuda, T.3
  • 81
    • 0032858556 scopus 로고    scopus 로고
    • A combinatorial approach to producing sterically stabilized (Stealth) immunoliposomal drugs
    • ISHIDA T, IDEN DL, ALLEN TM: A combinatorial approach to producing sterically stabilized (Stealth) immunoliposomal drugs. FEBS Lett. (1999) 460:129-133.
    • (1999) FEBS Lett. , vol.460 , pp. 129-133
    • Ishida, T.1    Iden, D.L.2    Allen, T.M.3
  • 82
    • 0035817346 scopus 로고    scopus 로고
    • In vitro and in vivo comparison of immunoliposomes made by conventional coupling techniques with those made by a new post-insertion approach
    • IDEN DL, ALLEN TM: In vitro and in vivo comparison of immunoliposomes made by conventional coupling techniques with those made by a new post-insertion approach. Biochim. Biophys. Acta (2001) 1513:207-216.
    • (2001) Biochim. Biophys. Acta , vol.1513 , pp. 207-216
    • Iden, D.L.1    Allen, T.M.2
  • 83
    • 0037731636 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells
    • MAMOT C, DRUMMOND DC, GREISER U et al.: Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells. Cancer Res. (2003) 63:3154-3161.
    • (2003) Cancer Res. , vol.63 , pp. 3154-3161
    • Mamot, C.1    Drummond, D.C.2    Greiser, U.3
  • 84
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • SALOMON DS, BRANDT R, CLkRDIELLO F, NORMANNO N: Epidermal growth factor-related peptides and their receptors in human malignancies. Crit. Rev. Oncol. Hematol. (1995) 19:183-232.
    • (1995) Crit. Rev. Oncol. Hematol. , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Clardiello, F.3    Normanno, N.4
  • 85
    • 0034722889 scopus 로고    scopus 로고
    • The EGF receptor family as targets for cancer therapy
    • MENDELSOHN J, BASELGA J: The EGF receptor family as targets for cancer therapy. Oncogene (2000) 19:6550-6565.
    • (2000) Oncogene , vol.19 , pp. 6550-6565
    • Mendelsohn, J.1    Baselga, J.2
  • 86
    • 0034799139 scopus 로고    scopus 로고
    • A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
    • CIARDIELLO F, TORTORA G: A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin. Cancer Res. (2001) 7:2958-2970.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2958-2970
    • Ciardiello, F.1    Tortora, G.2
  • 87
    • 0036554863 scopus 로고    scopus 로고
    • Anti-HER2 immunoliposomes: Enhanced efficay attributable to targeted delivery
    • PARK JW, HONG K, KIRPOTIN DB et al.: Anti-HER2 immunoliposomes: enhanced efficay attributable to targeted delivery. Clin. Cancer Res. (2002) 8:1172-1181.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1172-1181
    • Park, J.W.1    Hong, K.2    Kirpotin, D.B.3
  • 88
    • 0034805356 scopus 로고    scopus 로고
    • Biological effects of anti-ErbB2 single chain antibodies selected for internalizing function
    • NEVE RM, NIELSEN UB, KIRPOTIN DB et al.: Biological effects of anti-ErbB2 single chain antibodies selected for internalizing function. Biochem. Biophys. Res. Commun. (2001) 280:274-279.
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 274-279
    • Neve, R.M.1    Nielsen, U.B.2    Kirpotin, D.B.3
  • 90
    • 0035575846 scopus 로고    scopus 로고
    • Targeting Stealth liposomes in a murine model of human small cell lung cancer
    • MOREIRA JN, GASPAR R, ALLEN TM: Targeting Stealth liposomes in a murine model of human small cell lung cancer. Biochim. Biophys. Acta (2001) 1515:167-176.
    • (2001) Biochim. Biophys. Acta , vol.1515 , pp. 167-176
    • Moreira, J.N.1    Gaspar, R.2    Allen, T.M.3
  • 91
    • 0038105280 scopus 로고    scopus 로고
    • Development of Fab' fragments of anti-GD(2) immunoliposomes entrapping doxorubicin for experimental therapy of human neuroblastoma
    • BRIGNOLE C, MARIMPIETRI D, GAMBINI C et al.: Development of Fab' fragments of anti-GD(2) immunoliposomes entrapping doxorubicin for experimental therapy of human neuroblastoma. Cancer Lett. (2003) 197:199-204.
    • (2003) Cancer Lett. , vol.197 , pp. 199-204
    • Brignole, C.1    Marimpietri, D.2    Gambini, C.3
  • 92
    • 0032957035 scopus 로고    scopus 로고
    • GD2-mediated melanoma cell targeting and cytotoxicity of liposome-entrapped fenretinide
    • PAGNAN G, MONTALDO PG, PASTORINO F et al.: GD2-mediated melanoma cell targeting and cytotoxicity of liposome-entrapped fenretinide. Int. J. Cancer (1999) 81:268-274.
    • (1999) Int. J. Cancer , vol.81 , pp. 268-274
    • Pagnan, G.1    Montaldo, P.G.2    Pastorino, F.3
  • 93
    • 0036568415 scopus 로고    scopus 로고
    • Intracellular targeting therapy of cisplatin-encapsulated transferrin-polyethylene glycol liposome on peritoneal dissemination of gastric cancer
    • IINUMA H, MARUYAMA K, OKINAGA K et al.: Intracellular targeting therapy of cisplatin-encapsulated transferrin-polyethylene glycol liposome on peritoneal dissemination of gastric cancer. Int. J. Cancer. (2002) 99:130-137.
    • (2002) Int. J. Cancer , vol.99 , pp. 130-137
    • Iinuma, H.1    Maruyama, K.2    Okinaga, K.3
  • 94
    • 0037401058 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor activity of liposomal Fenretinide targeted to human neuroblastoma
    • RAFFAGHELLO L, PAGNAN G, PASTORINO F et al.: In vitro and in vivo antitumor activity of liposomal Fenretinide targeted to human neuroblastoma. Int. J. Cancer (2003) 104:559-567.
    • (2003) Int. J. Cancer , vol.104 , pp. 559-567
    • Raffaghello, L.1    Pagnan, G.2    Pastorino, F.3
  • 96
    • 0029785716 scopus 로고    scopus 로고
    • Immunoliposome-mediated targeting of doxorubicin to human ovarian carcinoma in vitro and in vivo
    • VINGERHOEDS MH, STEERENBERG PA, HENDRIKS JJ et al.: Immunoliposome-mediated targeting of doxorubicin to human ovarian carcinoma in vitro and in vivo. Br. J. Cancer (1996) 74:1023-1029.
    • (1996) Br. J. Cancer , vol.74 , pp. 1023-1029
    • Vingerhoeds, M.H.1    Steerenberg, P.A.2    Hendriks, J.J.3
  • 97
    • 0035830589 scopus 로고    scopus 로고
    • Anti-MUC-1 immunoliposomal doxorubicin in the treatment of murine models of metastatic breast cancer
    • MOASE EH, QU W, ISHIDA T et al.: Anti-MUC-1 immunoliposomal doxorubicin in the treatment of murine models of metastatic breast cancer. Biochim. Biophys. Acta (2001) 1510:43-55.
    • (2001) Biochim. Biophys. Acta , vol.1510 , pp. 43-55
    • Moase, E.H.1    Qu, W.2    Ishida, T.3
  • 98
    • 0036734093 scopus 로고    scopus 로고
    • A reevaluation of integrins as regulators of angiogenesis
    • HYNES RO: A reevaluation of integrins as regulators of angiogenesis. Nat. Med. (2002) 8:918-921.
    • (2002) Nat. Med. , vol.8 , pp. 918-921
    • Hynes, R.O.1
  • 99
    • 0037453165 scopus 로고    scopus 로고
    • Peptide-targeted PEG-liposomes in anti-angiogenic therapy
    • JANSSEN AP, SCHIFFELERS RM, TEN HAGEN TL et al.: Peptide-targeted PEG-liposomes in anti-angiogenic therapy. Int. J. Pharm. (2003) 254:55-58.
    • (2003) Int. J. Pharm. , vol.254 , pp. 55-58
    • Janssen, A.P.1    Schiffelers, R.M.2    Ten Hagen, T.L.3
  • 100
    • 0034213767 scopus 로고    scopus 로고
    • Targeting of endothelial KDR receptors with 3G2 immunoliposomes in vitro
    • BENZINGER P, MARTINY-BARON G, REUSCH P et al.: Targeting of endothelial KDR receptors with 3G2 immunoliposomes in vitro. Biochim. Biophys. Acta (2000) 1466:71-78.
    • (2000) Biochim. Biophys. Acta , vol.1466 , pp. 71-78
    • Benzinger, P.1    Martiny-Baron, G.2    Reusch, P.3
  • 104
    • 10744233861 scopus 로고    scopus 로고
    • Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy
    • PASTORINO F, BRIGNOLE C, MARIMPIETRI D et al.: Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy. Cancer Res. (2003) 63:7400-7409.
    • (2003) Cancer Res. , vol.63 , pp. 7400-7409
    • Pastorino, F.1    Brignole, C.2    Marimpietri, D.3
  • 106
    • 0023447252 scopus 로고
    • Lipofectin: A highly efficient, lipid-mediated DNA-transfection procedure
    • FELGNER PL, GADEK TR, HOLM M et al.: Lipofectin: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA (1987) 84:7413-7417.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7413-7417
    • Felgner, P.L.1    Gadek, T.R.2    Holm, M.3
  • 107
    • 0033977066 scopus 로고    scopus 로고
    • A new liposomal formulation for antisense oligodeoxynucleotides with small size, high incorporation efficiency and good stability
    • STUART DD, ALLEN TM: A new liposomal formulation for antisense oligodeoxynucleotides with small size, high incorporation efficiency and good stability, Biochim. Biophys. Acta (2000) 1463:219-229.
    • (2000) Biochim. Biophys. Acta , vol.1463 , pp. 219-229
    • Stuart, D.D.1    Allen, T.M.2
  • 108
    • 0030015493 scopus 로고    scopus 로고
    • Formation of stable cationic lipid/DNA complexes for gene transfer
    • HOFLAND HE, SHEPHARD L, SULLIVAN SM: Formation of stable cationic lipid/DNA complexes for gene transfer. Proc. Natl. Acad. Sci. USA (1996) 93:7305-7309.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7305-7309
    • Hofland, H.E.1    Shephard, L.2    Sullivan, S.M.3
  • 109
    • 0035039280 scopus 로고    scopus 로고
    • Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes
    • MAURER N, WONG KF, STARK H et al.: Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes. Biophys. J. (2001) 80:2310-2326.
    • (2001) Biophys. J. , vol.80 , pp. 2310-2326
    • Maurer, N.1    Wong, K.F.2    Stark, H.3
  • 111
    • 0031023264 scopus 로고    scopus 로고
    • Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery
    • HONG KL, ZHENG WW, BAKER A, PAPAHADJOPOULOS D: Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery. FEBS Lett. (1997) 400:233-237.
    • (1997) FEBS Lett. , vol.400 , pp. 233-237
    • Hong, K.L.1    Zheng, W.W.2    Baker, A.3    Papahadjopoulos, D.4
  • 112
    • 0034103894 scopus 로고    scopus 로고
    • Stabilized plasmid-lipid particles: Pharmacokinetics and plasmid delivery to distal tumors following intravenous injection
    • MONCK MA, MORI A, LEE D et al.: Stabilized plasmid-lipid particles: pharmacokinetics and plasmid delivery to distal tumors following intravenous injection. J. Drug Target (2000) 7:439-452.
    • (2000) J. Drug Target , vol.7 , pp. 439-452
    • Monck, M.A.1    Mori, A.2    Lee, D.3
  • 113
    • 0034033621 scopus 로고    scopus 로고
    • A novel, long-circulating, and functional liposomal formulation of anti-sense oligodeoxynucleotides targeted against MDR1
    • STUART DD, KAO GY, ALLEN TM: A novel, long-circulating, and functional liposomal formulation of anti-sense oligodeoxynucleotides targeted against MDR1. Cancer Gene Ther. (2000) 7-466-475.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 466-475
    • Stuart, D.D.1    Kao, G.Y.2    Allen, T.M.3
  • 115
    • 0036859261 scopus 로고    scopus 로고
    • Folate-targeted, cationic liposome-mediated gene transfer into disseminated peritoneal tumors
    • REDDY JA, ABBURI C, HOFLAND H et al.: Folate-targeted, cationic liposome-mediated gene transfer into disseminated peritoneal tumors. Gene Ther. (2002) 9:1542-1550.
    • (2002) Gene Ther. , vol.9 , pp. 1542-1550
    • Reddy, J.A.1    Abburi, C.2    Hofland, H.3
  • 116
    • 0038116522 scopus 로고    scopus 로고
    • Folate-liposome-mediated antisense oligodeoxynucleotide targeting to cells: Evaluation in vitro and in vivo
    • LEAMON CP, COOPER SR, HARDEE GE: Folate-liposome-mediated antisense oligodeoxynucleotide targeting to cells: Evaluation in vitro and in vivo. Bioconjug. Chem. (2003) 14:738-747.
    • (2003) Bioconjug. Chem. , vol.14 , pp. 738-747
    • Leamon, C.P.1    Cooper, S.R.2    Hardee, G.E.3
  • 117
    • 0030180001 scopus 로고    scopus 로고
    • Use of targeted cationic liposomes in enhanced DNA delivery to cancer cells
    • KAO GY, CHANGE LJ, ALLEN TM: Use of targeted cationic liposomes in enhanced DNA delivery to cancer cells. Cancer Gene Ther. (1996) 4:250-256.
    • (1996) Cancer Gene Ther. , vol.4 , pp. 250-256
    • Kao, G.Y.1    Change, L.J.2    Allen, T.M.3
  • 119
    • 10744233586 scopus 로고    scopus 로고
    • Targeted liposomal c-myc antisense oligonucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models
    • PASTORINO F, BRIGNOLE C, MARIMPIETRI D et al.: Targeted liposomal c-myc antisense oligonucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models. Clin. Cancer Res. (2003) 9:4595-4605.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 4595-4605
    • Pastorino, F.1    Brignole, C.2    Marimpietri, D.3
  • 120
    • 0642336863 scopus 로고    scopus 로고
    • Antibody targeted gene transfer to endothelium
    • TAN PH, MANUNTA M, ARDJOMAND N et al.: Antibody targeted gene transfer to endothelium. J. Gene Med. (2003) 5:311-323.
    • (2003) J. Gene Med. , vol.5 , pp. 311-323
    • Tan, P.H.1    Manunta, M.2    Ardjomand, N.3
  • 121
    • 0034691050 scopus 로고    scopus 로고
    • Noninvasive gene targeting to the brain
    • SHI N, PARDRIDGE W: Noninvasive gene targeting to the brain. Proc. Natl. Acad. Sci. USA (2000) 97:7567-7572.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7567-7572
    • Shi, N.1    Pardridge, W.2
  • 123
    • 0032546804 scopus 로고    scopus 로고
    • Cationic liposomes coated with polyethylene glycol as carriers of oligonucleotides
    • MEYER O, KIRPOTIN D, HONG K et al.: Cationic liposomes coated with polyethylene glycol as carriers of oligonucleotides. J. Biol. Chem. (1998) 273:15621-15627.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15621-15627
    • Meyer, O.1    Kirpotin, D.2    Hong, K.3
  • 124
    • 0029880651 scopus 로고    scopus 로고
    • Toward cell-targeting gene therapy vectors: Selection of cell-binding peptides from random peptide-presenting phage libraries
    • BARRY MA, DOWER WJ, JOHNSTON SA: Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries. Nat. Med. (1996) 2-299-305.
    • (1996) Nat. Med. , vol.2 , pp. 299-305
    • Barry, M.A.1    Dower, W.J.2    Johnston, S.A.3
  • 125
    • 0036077205 scopus 로고    scopus 로고
    • Development of EGF-conjugated liposomes for targeted delivery of boronated DNA-binding agents
    • BOHL KULLBERG E, BERGSTRAND N, CARLSSON J et al.: Development of EGF-conjugated liposomes for targeted delivery of boronated DNA-binding agents. Bioconjug. Chem. (2002) 13:737-743.
    • (2002) Bioconjug. Chem. , vol.13 , pp. 737-743
    • Bohl Kullberg, E.1    Bergstrand, N.2    Carlsson, J.3
  • 126
    • 0036518450 scopus 로고    scopus 로고
    • Receptor-mediated delivery of an antisense gene to human brain cancer cells
    • ZHANG Y, JEONG LEE H, BOADO RJ, PARDRIDGE WM: Receptor-mediated delivery of an antisense gene to human brain cancer cells. J. Gene Med (2002) 4:183-194.
    • (2002) J. Gene Med. , vol.4 , pp. 183-194
    • Zhang, Y.1    Jeong Lee, H.2    Boado, R.J.3    Pardridge, W.M.4
  • 127
    • 0032508960 scopus 로고    scopus 로고
    • Diplasmenylcholine-folate liposomes: An efficient vehicle for intracellular drug delivery
    • RUI Y, WANG S, LOW PS, THOMSON DH: Diplasmenylcholine-folate liposomes: an efficient vehicle for intracellular drug delivery. J. Am. Chem. Soc. (1998) 120:11213-11218.
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 11213-11218
    • Rui, Y.1    Wang, S.2    Low, P.S.3    Thomson, D.H.4
  • 128
    • 0030447660 scopus 로고    scopus 로고
    • Brain drug delivery of small moleculaes using immunoliposomes
    • HUWYLER J, WU D, PARDRIDGE WM: Brain drug delivery of small moleculaes using immunoliposomes. Proc. Natl. Acad. Sci. USA (1996) 93:14164-14169.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14164-14169
    • Huwyler, J.1    Wu, D.2    Pardridge, W.M.3
  • 129
    • 0034075131 scopus 로고    scopus 로고
    • Targeted drug delivery to C6 glioma by transferrin-coupled liposomes
    • EAVARONE DA, YU X, BELLAMKONDA RV: Targeted drug delivery to C6 glioma by transferrin-coupled liposomes. J. Biomed. Mater. Res. (2000) 51:10-14.
    • (2000) J. Biomed. Mater. Res. , vol.51 , pp. 10-14
    • Eavarone, D.A.1    Yu, X.2    Bellamkonda, R.V.3
  • 130
    • 0036649819 scopus 로고    scopus 로고
    • Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes
    • MARTY C, ODERMATT B, SCHOTT H et al.: Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes. Br. J. Cancer (2002) 87:106-112.
    • (2002) Br. J. Cancer , vol.87 , pp. 106-112
    • Marty, C.1    Odermatt, B.2    Schott, H.3
  • 131
    • 0141886984 scopus 로고    scopus 로고
    • VIP grafted sterically sterilized liposomes for targeted imaging of breast cancer: In vivo studies
    • DAGAR S, KRISHNADAS A, RUBINSTEIN I, BLEND MJ, ONYUKSEL H: VIP grafted sterically sterilized liposomes for targeted imaging of breast cancer: in vivo studies. J. Control. Release (2003) 91:123-133.
    • (2003) J. Control Release , vol.91 , pp. 123-133
    • Dagar, S.1    Krishnadas, A.2    Rubinstein, I.3    Blend, M.J.4    Onyuksel, H.5
  • 132
    • 1042290308 scopus 로고    scopus 로고
    • Improved therapeutic responses in a xenograft model of human B lymphoma (Namalwa) for liposomal vincristine versus liposomal doxorubicin targeted via anti-CD19 IgG2a or Fab' fragments
    • SAPRA P, MOASE EH, MA J, ALLEN TM: Improved therapeutic responses in a xenograft model of human B lymphoma (Namalwa) for liposomal vincristine versus liposomal doxorubicin targeted via anti-CD19 IgG2a or Fab' fragments. Clin. Cancer Res. (2004) 10:1100-1111.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1100-1111
    • Sapra, P.1    Moase, E.H.2    Ma, J.3    Allen, T.M.4
  • 133
    • 0035834268 scopus 로고    scopus 로고
    • Possibility of the reversal of multidrug resistance and the aviodance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein
    • MATSUO H, WAKASUGI M, TAKANAGA H et al.: Possibility of the reversal of multidrug resistance and the aviodance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein. J. Control. Release (2001) 77:77-86.
    • (2001) J. Control Release , vol.77 , pp. 77-86
    • Matsuo, H.1    Wakasugi, M.2    Takanaga, H.3


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