Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes

Journal of Molecular Biology

Volumn 371, Issue 1, 2007, Pages 93-111

  Singh, Umesh P ^a   Ardelt, Wojciech ^b   Saxena, Shailendra K ^b   Holloway, Daniel E ^a   Vidunas, Eugene ^b   Lee, Hung Suen ^b   Saxena, Abha ^b   Shogen, Kuslima ^b   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b Alfacell Corporation   (United States)

Author keywords

Amphinase; cytotoxic RNase; enzyme efficiency; substrate specificity; X ray crystallography

Indexed keywords

ADENINE; AMINO ACID; AMPHINASE; CYSTEINE; CYTOSINE; GLYCAN; GUANINE; RANPIRNASE; RECOMBINANT ENZYME; RIBONUCLEASE; RIBONUCLEASE A; RIBONUCLEASE INHIBITOR; RNA; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; URACIL;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; AMPHIBIA; ANIMAL CELL; ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME GLYCOSYLATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; FEMALE; FROG; MOLECULAR DYNAMICS; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN FOLDING; SEQUENCE ANALYSIS;

AMPHIBIA; RANA PIPIENS;

EID: 34447094846     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.04.071     Document Type: Article

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