His···Asp catalytic dyad of ribonuclease A: Structure and function of the wild-type, D121N, and D121A enzymes

Biochemistry

Volumn 37, Issue 25, 1998, Pages 8886-8898

  Wayne Schultz, L ^a   Quirk, David J ^a   Raines, Ronald T ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEASE; ALANINE; ASPARAGINE; ASPARTIC ACID; HISTIDINE; LYSINE; PANCREATIC RIBONUCLEASE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANIMAL; BINDING SITE; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; PH; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

ALANINE; ANIMALS; ASPARAGINE; ASPARTIC ACID; BINDING SITES; CATALYSIS; CATTLE; CRYSTALLOGRAPHY, X-RAY; HISTIDINE; HYDROGEN-ION CONCENTRATION; LYSINE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; RIBONUCLEASE, PANCREATIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032560446     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972766q     Document Type: Article

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