Attenuation of kupffer cell function in acute on chronic liver injury enhanced engraftment of transplanted hepatocytes

World Journal of Surgery

Volumn 31, Issue 6, 2007, Pages 1270-1277

  Yuan, Ray Hwang ^a   Chen, Hui Ling ^a   Chen, Huey Ling ^a   Hsu, Ming Kung ^a   Lee, Po Huang ^a   Chang, Mei Hwei ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; LIPOPOLYSACCHARIDE; MESSENGER RNA; PARACETAMOL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSPLANTATION; CONTROLLED STUDY; ENGRAFTMENT; KUPFFER CELL; LIVER CELL; LIVER INJURY; MICROSCOPE; MOUSE; NONHUMAN; STATISTICAL SIGNIFICANCE; SURGICAL TECHNIQUE;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD26; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELL DIVISION; CELL SURVIVAL; HEPATITIS, TOXIC; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LIVER; LIVER FAILURE; LIVER FUNCTION TESTS; LIVER REGENERATION; MICE; MICROSCOPY, FLUORESCENCE; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34447093032     PISSN: 03642313     EISSN: 14322323     Source Type: Journal    
DOI: 10.1007/s00268-007-9044-0     Document Type: Article

References (35)

1. Laconi S, Pillai S, Porcu PP, et al. (2001) Massive liver replacement by transplanted hepatocytes in the absence of exogenous growth stimuli in rats treated with retrorsine. Am J Pathol 158:771-777
2. Laconi E, Oren R, Mukhopadhyay DK, et al. (1998) Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine. Am J Pathol 153:319-329
3. Lazerow SK, Abdi MS, Lewis JH (2005) Drug-induced liver disease 2004. Curr Opin Gastroenterol 21:283-292
4. Mitchell JR, Jollow DJ, Potter WZ, et al. (1973) Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther 187:211-217
5. Qiu Y, Benet LZ, Burlingame AL (1998) Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry. J Biol Chem 273:17940-17953
6. Cohen SD, Khairallah EA (1997) Selective protein arylation and acetaminophen-induced hepatotoxicity. Drug Metab Rev 29:59-77
7. Michael SL, Pumford NR, Mayeux PR, et al. (1999) Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species. Hepatology 30:186-195
8. Nguyen TH, Mai G, Villiger P, et al. (2005) Treatment of acetaminophen-induced acute liver failure in the mouse with conditionally immortalized human hepatocytes. J Hepatol 43:1031-1037
9. Gupta S, Rajvanshi P, Sokhi RP, et al. (1999) Entry and integration of transplanted hepatocytes in liver plates occur by disruption of hepatic sinusoidal endothelium. Hepatology 29:509-519
10. Gupta S, Rajvanshi P, Malhi H, et al. (2000) Cell transplantation causes loss of gap junctions and activates GGT expression permanently in host liver. Am J Physiol Gastrointest Liver Physiol 279:G815-G826
11. Slehria S, Rajvanshi P, Ito Y, et al. (2002) Hepatic sinusoidal vasodilators improve transplanted cell engraftment and ameliorate microcirculatory perturbations in the liver. Hepatology 35:1320-1328
12. Lemasters JJ, Thurman RG (1997) Reperfusion injury after liver preservation for transplantation. Annu Rev Pharmacol Toxicol 37:327-338
13. Serracino-Inglott F, Habib NA, Mathie RT (2001) Hepatic ischemia-reperfusion injury. Am J Surg 181:160-166
14. Luckey SW, Petersen DR (2001) Activation of Kupffer cells during the course of carbon tetrachloride-induced liver injury and fibrosis in rats. Exp Mol Pathol 71:226-240
15. Blazka ME, Wilmer JL, Holladay SD, et al. (1995) Role of proinflammatory cytokines in acetaminophen hepatotoxicity. Toxicol Appl Pharmacol 13:43-52
16. Bruccoleri A, Gallucci R, Germolec DR, et al. (1997) Induction of early-immediate genes by tumor necrosis factor-α contributes to liver repair following chemical-induced hepatotoxicity. Hepatology 25:133-140
17. Yuan RH, Ogawa A, Ogawa E, et al. (2003) p27Kip1 inactivation provides a proliferative advantage to transplanted hepatocytes in DPPIV/Rag2 double knockout mice after repeated host liver injury. Cell Transplant 12:907-919
18. Mathew J, Hines JE, Toole K, et al. (1994) Quantitative analysis of macrophages and perisinusoidal cells in primary biliary cirrhosis. Histopathology 25:65-70
19. Micklen K, Rigney E, Cordell J, et al. (1989) A human macrophage-associated antigen (CD68) detected by six different monoclonal antibodies. Br J Haematol 73:6-11
20. Brown KE, Brunt EM, Heinecke JW (2001) Immunohistochemical detection of myeloperoxidase and its oxidation products in Kupffer cells of human liver. Am J Pathol 159:2081-2088
21. Su GL, Klein RD, Aminlari A, et al. (2000) Kupffer cell activation by lipopolysaccharide in rats: role for lipopolysaccharide binding protein and toll-like receptor 4. Hepatology 31:932-936
22. Yuan RH, Jeng YM, Chen HL, et al. (2005) Opposite roles of human PAP and REG1A expression in hepatocellular carcinoma (HCC): association of PAP expression with low-stage HCC, β-catenin mutation, and favorable prognosis. Clin Cancer Res 11:2568-2575
23. Nagayama T, Nagayama M, Kohara S, et al. (2004) Post-ischemic delayed expression of hepatocyte growth factor and c-Met in mouse brain following focal cerebral ischemia. Brain Res 999:155-166
24. Gujral JS, Knight TR, Farhood A, et al. (2002) Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis? Toxicol Sci 67:322-328
25. Crofton RW, Diesselhoff-den Dulk MM, Van Furth R (1978) The origin, kinetics and characteristics of the Kupffer cells in the normal steady state. J Exp Med 148:1-17
26. Joseph B, Malhi H, Bhargava KK, et al. (2002) Kupffer cells participate in early clearance of syngeneic hepatocytes transplanted in the rat liver. Gastroenterology 123:1677-1685
27. Fukuda M, Yokoyama H, Mizukami T, et al. (2004) Kupffer cell depletion attenuates superoxide anion release into the hepatic sinusoids after lipopolysaccharide treatment. J Gastroenterol Hepatol 19:1155-1162
28. Ishizaki-Koizumi S, Sonaka I, Takei Y, et al. (2004) The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-alpha in isolated rat Kupffer cells and exerts hepatoprotective effects in mice. Biochem Biophys Res Commun 322:514-519
29. Barshes NR, Wyllie S, Goss JA (2005) Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic grafts. J Leukocyte Biol 77:587-597
30. Bottino R, Fernandez LA, Ricordi C, et al. (1988) Transplantation of allogeneic islets of Langerhans in the rat liver: effects of macrophage depletion on graft survival and microenvironment activation. Diabetes 47:316-323
31. Laskin DL, Pendino KJ (1995) Macrophages and inflammatory mediators in tissue injury. Annu Rev Pharmacol Toxicol 35:655-677
32. Ito Y, Bethea NW, Abril ER, et al. (2003) Early hepatic microvascular injury in response to acetaminophen toxicity. Microcirculation 10:391-400
33. Michalopoulos GK, DeFrances MC (1997) Liver regeneration. Science 276:60-66
34. Kaido T, Imamura M (2001) Hepatocyte growth factor: clinical implications in hepatobiliary pancreatic surgery. J Hepatobiliary Pancreat Surg 8:65-75
35. Matsumoto K, Nakamura T (1991) Hepatocyte growth factor: molecular structure and implications for a central role in liver regeneration. J Gastroenterol Hepatol 6:509-519