Cerebral uptake of drugs in humans

Clinical and Experimental Pharmacology and Physiology

Volumn 34, Issue 8, 2007, Pages 695-701

  Upton, Richard N ^a  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

Author keywords

Brain; Human; Mass balance; Microdialysis; Pharmacodynamics; Pharmacokinetics; Pharmacology; Positron emission tomography (PET); Review; Uptake

Indexed keywords

ALFENTANIL; ANTICONVULSIVE AGENT; BENZODIAZEPINE RECEPTOR; CARBON 11; CENTRAL NERVOUS SYSTEM AGENTS; CYCLODEXTRIN; FENTANYL; FLUORINE 18; GLYCOPROTEIN P; LOPERAMIDE; NITROGEN 13; OXYGEN 15; PROPOFOL; QUINIDINE; RADIOISOTOPE; RIFAMPICIN; VANCOMYCIN; VERAPAMIL; VINPOCETINE;

ANESTHESIA; ARTERIAL BLOOD; BLOOD BRAIN BARRIER; BRAIN ARTERY; BRAIN BLOOD FLOW; BRAIN VEIN; CENTRAL NERVOUS SYSTEM; DNA POLYMORPHISM; DOSE RESPONSE; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG EFFECT; DRUG HALF LIFE; DRUG METABOLISM; DRUG TOLERANCE; DRUG UPTAKE; FIRST PASS EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER CLEARANCE; MICRODIALYSIS; NEUROIMAGING; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT MONITORING; PHARMACODYNAMICS; POSITRON EMISSION TOMOGRAPHY; SHORT SURVEY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; VENOUS BLOOD;

BLOOD-BRAIN BARRIER; BRAIN; CENTRAL NERVOUS SYSTEM AGENTS; DRUG ADMINISTRATION ROUTES; HUMANS; JUGULAR VEINS; MICRODIALYSIS; MODELS, BIOLOGICAL; PHARMACOLOGY, CLINICAL; POSITRON-EMISSION TOMOGRAPHY; TISSUE DISTRIBUTION;

EID: 34347338588     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2007.04649.x     Document Type: Short Survey

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