Measurement of blood-brain barrier permeability of rats with alpha-aminoisobutyric acid during microdialysis: Possible application to behavioral studies

Physiology and Behavior

Volumn 67, Issue 4, 1999, Pages 587-598

  Choi, Yang Ho ^a   Fletcher, Paul J ^a   Wong, Cecilia C S ^a   Anderson, G Harvey ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Amino acids; Brain transport; Evans blue dye; Feeding behavior

Indexed keywords

2 AMINO 2 METHYLPROPIONIC ACID;

AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; BLOOD BRAIN BARRIER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032849868     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(99)00110-9     Document Type: Article

References (46)

1. Aasmundstad T.A., Morland J., Paulsen R.E. Distribution of morphine 6-glucuronide and morphine across the blood-brain barrier in awake, freely moving rats investigated by in vivo microdialysis sampling. J. Pharmacol. Exp. Ther. 275:1995;435-441.
2. Ablett R.F., MacMillan M., Sole M.J., Toal C.B., Anderson G.H. Free tyrosine levels of rat brain and tissues with sympathetic innervation following administration of L-tyrosine in the presence and absence of large neutral amino acids. J. Nutr. 114:1984;835-839.
3. Allen D.D., Crooks P.A., Yokel R.A. 4-Trimethylammonium antipyrine. A quaternary ammonium nonradionuclide marker for blood-brain barrier integrity during in vivo microdialysis J. Pharmacol. Toxicol. Methods. 28:1992;129-135.
4. Anderson G.H. Metabolic regulation of food intake. Shils M.E., Young V.R. Modern nutrition in health and disease. 3rd ed:1999;557-569 Lea & Febiger, Philadelphia.
5. Anderson G.H., Luo S., Trigazis L., Kubis G., Li E.T.S. Effects of essential amino acids on food and water intake of rats. Can. J. Physiol. Pharmacol. 72:1994;841-848.
6. Begley D.J., Reichel A., Ermisch A. Simple high-performance liquid chromatographic analysis of free primary amino acid concentrations in rat plasma and cisternal cerebrospinal fluid. J. Chromatogr. B Biomed. Appl. 657:1994;185-191.
7. Benrabh H., Lefauconnier J.M. Blood-endothelial cell and blood-brain transport of L-proline, alpha-aminoisobutyric acid, and L-alanine. Neurochem. Res. 21:1996;1227-1235.
8. Benveniste H. Brain microdialysis. J. Neurochem. 52:1989;1667-1689.
9. Benveniste H., Diemer N.H. Cellular reactions to implantation of a microdialysis tube in the rat hippocampus. Acta Neuropathol. 74:1987;234-238.
10. Benveniste H., Drejer J., Schousboe A., Diemer N.H. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43:1984;1369-1374.
11. Bereiter D.A., Benetti A.P. Excitatory amino release within spinal trigeminal nucleus after mustard oil injection into the temporomandibular joint region of the rat. Pain. 67:1996;451-459.
12. Betz A.L., Goldenstein G.W., Katzman R. Blood-brain-cerebrospinal fluid barriers. Siegel G.J., Agranoff B.W., Albers R.W., Molinoff P.B. Basic neurochemistry. Molecular, cellular, and medical aspects 5th ed:1994;681-699 Raven Press, New York.
13. Blasberg R.G., Fenstermacher J.D., Patlak C.S. Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes. J. Cereb. Blood Flow Metab. 3:1983;8-32.
14. Blasberg R.G., Gazendam J., Patlak C.S., Fenstermacher J.D. Quantitative autoradiographic studies of brain edema and a comparison of multi-isotope autoradiographic technique. Adv. Neurol. 28:1980;255-270.
15. Christensen H.N., Cullen A.M. Effects of non-metabolizable analogs on the distribution of amino acids in the rat. Biochim. Biophys. Acta. 150:1968;237-252.
16. Currie P.J., Chang N., Luo S., Anderson G.H. Microdialysis as a tool to measure dietary and regional effects on the complete profile of extracellular amino acids in the hypothalamus of rats. Life Sci. 57:1995;1911-1923.
17. Davson H. The blood-brain barrier. J. Physiol. 255:1976;1-28.
18. Davson H., Begley D.J., Chain D.G., Briggs F.O., Shepard M.T. Steady-state distribution of cycloleucine and alpha-aminoisobutyric acid between plasma and cerebrospinal fluid. Exp. Neurol. 91:1986;163-173.
19. De Lange E.C.M., Danhof M., de Boer A.G., Breimer D.D. Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood-brain barrier. Brain Res. Rev. 25:1997;27-49.
20. De Lange E.C.M., Danhof M., Zurcher C., de Boer A.G., Breimer D.D. Repeated microdialysis perfusions. Periprobe tissue reactions and BBB permeability Brain Res. 702:1995;261-265.
21. Dickson P.R., Feifel D., Vaccarino F.J. Blockade of endogenous GRF at dark onset selectively suppresses protein intake. Peptides. 16:1995;7-9.
22. Dykstra K.H., Hsiao J.K., Morrison P.F., Bungay P.M., Mefford I.N., Scully M.M., Dedrick R.L. Quantitative examination of tissue concentration profiles associated with microdialysis. J. Neurochem. 58:1992;931-940.
23. Ennis S.R., Ren X.D., Betz A.L. Transport of alpha-aminoisobutyric acid across the blood-brain barrier studied with in situ perfusion of rat brain. Brain Res. 643:1994;100-107.
24. Glanville N.T., Anderson G.H. The effect of insulin deficiency, dietary protein intake, and plasma amino acid concentrations on brain amino acid levels in rats. Can. J. Physiol. Pharmacol. 63:1985;487-494.
25. Goldsmith J.D., Kujawa S.G., McLaren J.D., Bledsoe S.C. Jr. In vivo release of neuroactive amino acids from the inferior colliculus of the guinea pig using brain microdialysis. Hear. Res. 83:1995;80-88.
26. Groothuis D.R., Ward S., Schlageter K.E., Itskovich A.C., Schwerin S.C., Allen C.V., Dills C., Levy R.M. Changes in blood-brain barrier permeability associated with insertion of brain cannulas and microdialysis probes. Brain Res. 803:1998;218-230.
27. Jaeger C.B., Winn S.R., Tresco P.A., Aebischer P. Repair of the blood-brain barrier following implantation of polymer capsules. Brain Res. 551:1991;163-170.
28. Jones H.C., Keep R.C. The control of potassium concentration in the cerebrospinal fluid and brain interstitial fluid of developing rats. J. Physiol. 383:1987;441-453.
29. 51-EDTA by microdialysis following probe injury. Acta Neurochir. Suppl. (Wien). 51:1990;46-48.
30. McAdoo D.J., Hughes M.G., Xu G.Y., Robak G., de Castro R. Jr. Microdialysis studies of the role of chemical agents in secondary damage upon spinal cord injury. J. Neurotrauma. 14:1997;507-515.
31. Morgan M.E., Singhal D., Anderson B.D. Quantitative assessment of blood-brain barrier damage during microdialysis. J. Pharmacol. Exp. Ther. 277:1996;1167-1176.
32. Oldendorf W.H. Brain uptake of radiolabeled amino acids, amines, and hexoses after art assignment to one of three blood-brain barrier amino acid carriers. Am. J. Physiol. 221:1971;1629-1639.
33. Oldendorf W.H., Szabo J. Amino acid assignment to one of three blood-brain barrier amino acid carriers. Am. J. Physiol. 230:1976;94-98.
34. Orosco M., Gerozissis K., Rouch C., Meile M.J., Nicolaidis S. Hypothalamic monoamines and insulin in relation to feeding in the genetically obese Zucker rat as reveled by microdialysis. Obes. Res. 3(Suppl 5):1995;655S-665S.
35. Pardridge W.M., Oldendorf W.H. Kinetic analysis of blood-brain barrier transport of amino acids. Biochim. Biophys. Acta. 401:1975;128-136.
36. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 2nd ed:1986;Academy Press, New York.
37. Pont F., Collet A., Lallement G. Early and transient increase of rat hippocampal blood-brain barrier permeability to amino acids during kainic acid-induced seizures. Neurosci. Lett. 184:1995;52-54.
38. Reichel A., Begley D.J., Ermisch A. Changes in amino acid levels in rat plasma, cisternal cerebrospinal fluid, and brain tissue induced by intravenously infused arginine-vasopressin. Peptides. 16:1995;965-971.
39. Sage J.I., Duffy T.E. Pentobarbital anesthesia. Influence on amino acid transport across the blood-brain barrier J. Neurochem. 33:1979;963-965.
40. Segal M.B., Zlokovic B. Amino acids and the blood-brain barrier. The blood-brain barrier, amino acids and peptides. 1990;13-46 Kluwer Academic Publishers, Dordercht, The Netherlands.
41. Stewart P.A., Hayakawa E.M., Carlen P.L. Ethanol and pentobarbital in combination increase blood-brain barrier permeability to horseradish peroxidase. Brain Res. 443:1988;12-20.
42. Tossman U., Ungerstedt U. Microdialysis in the study of extracellular levels of amino acids in the rat brain. Acta Physiol. Scand. 128:1986;9-14.
43. Vaccarino F.J., Taube M.R. Intra-arcuate opiate actions stimulate GRF-dependent and protein selective feeding. Peptides. 18:1997;197-205.
44. Westergren I., Nystrom B., Hamberger A., Johansson B.B. Intracerebral dialysis and the blood-brain barrier. J. Neurochem. 64:1995;229-234.
45. Westergren I., Nystrom B., Hamberger A., Nordborg C., Johansson B.B. Concentrations of amino acids in extracellular fluid after opening of the blood-brain barrier by intracarotid infusion of protamine sulfate. J. Neurochem. 62:1994;159-165.
46. Zhang J., Benveniste H., Klitzman B., Piantadosi C.L. Nitric oxide synthase inhibition and extracellular glutamate concentration after cerebral ischemia/reperfusion. Stroke. 26:1995;298-304.